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The map label for this gene is rnr

Identifier: 170762284

GI number: 170762284

Start: 70271

End: 72436

Strand: Direct

Name: rnr

Synonym: UPA3_0056

Alternate gene names: 170762284

Gene position: 70271-72436 (Clockwise)

Preceding gene: 170761913

Following gene: 170762068

Centisome position: 9.35

GC content: 27.38

Gene sequence:

>2166_bases
ATGAGTGATTTTACGAAACAAACTATTACCGAAGTAATTTCTAAGGAAGAGCGCCCAATACCCGCTGCTATTCTTGCTAA
AAAAGTGTTAGAAAAAATACCCACTTTAAATAAAACTGATGTTTATAAACTAATTGATTTATTAATTCAAGAAAATACTA
TTAAAAAATTAGAAAATAATCGATTGGTTATTGGTTATCTAGATTATGAATTTGATCACGAGATCAAACAAGGAATAATT
ACTATCAATTCAAAAGGTGATGGCTTCATTAAAGAAGATAATACTGAAATTGAATATTACGTCAACAAAAAATATTTAAA
TGGGGCTTTAAAAAAAGATTCAGTTAAATTTGTAAAGTTAAAAAAAGAACCTAAAAACAACCTGCAAGATGCTGCTGTAA
TTGAAATTGTTGGGCATGCTAAAGACCATTATGTTGGTCAATTTATAACTCTTCCTAATGGTGGTTATTACATTTTTGTT
GACGATCCTTTATTTTACTTAAATATAAATTTAAAAGATACTACCGGTTTAGTTAATGGTCACAAAATTCTTTTTAAAAT
TATTTCGCAAACAACAAAAGATGCTATTGCAGAATTAGTTCATATCATAGGTCATAAAAACGATGTTGGTTCTGATGTTT
TATCAATCGTTTATGATAATGGTATTGATCCAACTTTTGATCCACAAGTTGTTGATTTGGCTTCAAAATTAGAATTTTAT
GTTGATGAACATCAAAACAAAATTCGACGTTCAATAATTGATCGTGAAATTATTTCTATTGATCCTGTTGGTTCTAAAGA
TATTGATGATGCTGTTTATGTTAAAAAATTAAATGATCAACGTTACTTTTTAGGTATTTCTATTGCTGATGTTAGTTTTT
ATGTACAACCTAACACCATTCTTGATGCTGATGCTTTTAAAAGGGGAACATCAACATATTTAGTTGATCGTGTTATTCCA
ATGCTTCCGCATAATATTTCTAATAATATTTGTTCATTAAACGAAGGTGAGTTTCGCATGTGTATAACATGTGATATGGT
AATTGACAAAGATGGAAAAATATGTTGAAAAGATGTTTATCCTGCTATCATGAAAAATTATCGTCAAATGTCATATGATG
AAGTTAATGATTTTTATGAAGGAAAATCACGTTTTGAATCAGCAACATTAACTATGAAAGAAATGTTATTAGAAGCTAAA
GAATTGCACCATATTTTAAGAAATAAAAAAATTAAAGATGGTTATGTTGATTTTGATATTAAAGAACCAAAAATTATTTT
AGATGAAACTGGTGTCCCTATTGATATTAAAATTTACGAACGTAAAACTGCTCAAATGATGGTTGAAGATTTTATGATTG
CAGCTAATGAGGCTGTAACTATGTTTGCTGAAGAACACATGGATAAAACACTAAAAGAATTTAATTTAGAAATGCCTTTT
ATCTATCGTGTTCATGATAAACCATCAATTATTAACTTACAAAAATTTGAAATTGAGGCAAAAAAATTGAGTTTCAATAT
CTCACATGATTTTGAGAACATTCAACCTAACACTATTTCAAATTGACTAAAAATGAATGATAATCATGTTAACTTACCAT
TAATTAGTAAATTATTATTAAGATCAATGGCTAAAGCTTCTTATGAAATTATTAATACGGGACATTTTGGTTTAGCATCT
GATAACTATACACACTTTACATCACCAATACGGCGTTATCCAGATTTAATTGTACACCGTTTATTATGAATGTTTATTTT
TGATTCTCAAAGTTATACAGATAAACAACGAGTAGAATTAGTAAATAAACTGAAGTTAATTACTGAAGAATCAAATAAAA
ATGAAATTATAGCAGTTAAGACTGAACGTGATGTTAATGCTGCTAAATTTGCTGAATATATGAATTTACATATTGGTAAA
GAATTTATTGGTGTGGTAACAACAGTTTCTAGTTTTGGTGTTTTTGTTGAACTCGAAAATACGATTGAAGGTTTAATTAG
AATTAAAAATTTAAAAGATGATTTTTATGATTTTATTCCTGAAAACATGACTTTAGTTGGTCAAAAAAGAAAGAAAATTA
TTACTGTTGGCAATAAAGTTCGTGTACGTGTTATTGAAGCTAACAAACTTACAAGAAAAATTGATTTTGAACTAGTTGCA
CAATAA

Upstream 100 bases:

>100_bases
AAAAACAAAAGACCGTGGTTGAATTAAAGGTTTACAAGTCTTTATGTTTTTATTAACAATTGTTATGATTTTAATAATAA
TTTTTTATAGAGTGAGCTAG

Downstream 100 bases:

>100_bases
AAAATATAAGACTTAAAAAAATTTATTTATAATACACAAAGAAGATGACTAAAGTAAATATTTAGTCGTTTTTTAATTGC
TAATTATCATAAAATGTTAC

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 721; Mature: 720

Protein sequence:

>721_residues
MSDFTKQTITEVISKEERPIPAAILAKKVLEKIPTLNKTDVYKLIDLLIQENTIKKLENNRLVIGYLDYEFDHEIKQGII
TINSKGDGFIKEDNTEIEYYVNKKYLNGALKKDSVKFVKLKKEPKNNLQDAAVIEIVGHAKDHYVGQFITLPNGGYYIFV
DDPLFYLNINLKDTTGLVNGHKILFKIISQTTKDAIAELVHIIGHKNDVGSDVLSIVYDNGIDPTFDPQVVDLASKLEFY
VDEHQNKIRRSIIDREIISIDPVGSKDIDDAVYVKKLNDQRYFLGISIADVSFYVQPNTILDADAFKRGTSTYLVDRVIP
MLPHNISNNICSLNEGEFRMCITCDMVIDKDGKICWKDVYPAIMKNYRQMSYDEVNDFYEGKSRFESATLTMKEMLLEAK
ELHHILRNKKIKDGYVDFDIKEPKIILDETGVPIDIKIYERKTAQMMVEDFMIAANEAVTMFAEEHMDKTLKEFNLEMPF
IYRVHDKPSIINLQKFEIEAKKLSFNISHDFENIQPNTISNWLKMNDNHVNLPLISKLLLRSMAKASYEIINTGHFGLAS
DNYTHFTSPIRRYPDLIVHRLLWMFIFDSQSYTDKQRVELVNKLKLITEESNKNEIIAVKTERDVNAAKFAEYMNLHIGK
EFIGVVTTVSSFGVFVELENTIEGLIRIKNLKDDFYDFIPENMTLVGQKRKKIITVGNKVRVRVIEANKLTRKIDFELVA
Q

Sequences:

>Translated_721_residues
MSDFTKQTITEVISKEERPIPAAILAKKVLEKIPTLNKTDVYKLIDLLIQENTIKKLENNRLVIGYLDYEFDHEIKQGII
TINSKGDGFIKEDNTEIEYYVNKKYLNGALKKDSVKFVKLKKEPKNNLQDAAVIEIVGHAKDHYVGQFITLPNGGYYIFV
DDPLFYLNINLKDTTGLVNGHKILFKIISQTTKDAIAELVHIIGHKNDVGSDVLSIVYDNGIDPTFDPQVVDLASKLEFY
VDEHQNKIRRSIIDREIISIDPVGSKDIDDAVYVKKLNDQRYFLGISIADVSFYVQPNTILDADAFKRGTSTYLVDRVIP
MLPHNISNNICSLNEGEFRMCITCDMVIDKDGKIC*KDVYPAIMKNYRQMSYDEVNDFYEGKSRFESATLTMKEMLLEAK
ELHHILRNKKIKDGYVDFDIKEPKIILDETGVPIDIKIYERKTAQMMVEDFMIAANEAVTMFAEEHMDKTLKEFNLEMPF
IYRVHDKPSIINLQKFEIEAKKLSFNISHDFENIQPNTISN*LKMNDNHVNLPLISKLLLRSMAKASYEIINTGHFGLAS
DNYTHFTSPIRRYPDLIVHRLL*MFIFDSQSYTDKQRVELVNKLKLITEESNKNEIIAVKTERDVNAAKFAEYMNLHIGK
EFIGVVTTVSSFGVFVELENTIEGLIRIKNLKDDFYDFIPENMTLVGQKRKKIITVGNKVRVRVIEANKLTRKIDFELVA
Q
>Mature_720_residues
SDFTKQTITEVISKEERPIPAAILAKKVLEKIPTLNKTDVYKLIDLLIQENTIKKLENNRLVIGYLDYEFDHEIKQGIIT
INSKGDGFIKEDNTEIEYYVNKKYLNGALKKDSVKFVKLKKEPKNNLQDAAVIEIVGHAKDHYVGQFITLPNGGYYIFVD
DPLFYLNINLKDTTGLVNGHKILFKIISQTTKDAIAELVHIIGHKNDVGSDVLSIVYDNGIDPTFDPQVVDLASKLEFYV
DEHQNKIRRSIIDREIISIDPVGSKDIDDAVYVKKLNDQRYFLGISIADVSFYVQPNTILDADAFKRGTSTYLVDRVIPM
LPHNISNNICSLNEGEFRMCITCDMVIDKDGKIC*KDVYPAIMKNYRQMSYDEVNDFYEGKSRFESATLTMKEMLLEAKE
LHHILRNKKIKDGYVDFDIKEPKIILDETGVPIDIKIYERKTAQMMVEDFMIAANEAVTMFAEEHMDKTLKEFNLEMPFI
YRVHDKPSIINLQKFEIEAKKLSFNISHDFENIQPNTISN*LKMNDNHVNLPLISKLLLRSMAKASYEIINTGHFGLASD
NYTHFTSPIRRYPDLIVHRLL*MFIFDSQSYTDKQRVELVNKLKLITEESNKNEIIAVKTERDVNAAKFAEYMNLHIGKE
FIGVVTTVSSFGVFVELENTIEGLIRIKNLKDDFYDFIPENMTLVGQKRKKIITVGNKVRVRVIEANKLTRKIDFELVAQ

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=425, Percent_Identity=30.5882352941176, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI190014625, Length=425, Percent_Identity=30.5882352941176, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI134288890, Length=412, Percent_Identity=27.1844660194175, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI19115966, Length=423, Percent_Identity=27.4231678486998, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI219521928, Length=423, Percent_Identity=27.4231678486998, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI156105695, Length=376, Percent_Identity=22.8723404255319, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI156105693, Length=364, Percent_Identity=22.8021978021978, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI87082383, Length=653, Percent_Identity=27.8713629402757, Blast_Score=273, Evalue=3e-74,
Organism=Escherichia coli, GI1787542, Length=426, Percent_Identity=24.8826291079812, Blast_Score=126, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI212645896, Length=481, Percent_Identity=27.2349272349272, Blast_Score=158, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17553506, Length=427, Percent_Identity=28.3372365339578, Blast_Score=151, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6324552, Length=479, Percent_Identity=28.1837160751566, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24649634, Length=363, Percent_Identity=29.4765840220386, Blast_Score=165, Evalue=1e-40,
Organism=Drosophila melanogaster, GI19922976, Length=471, Percent_Identity=25.9023354564756, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24654597, Length=471, Percent_Identity=25.9023354564756, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24654592, Length=471, Percent_Identity=25.9023354564756, Blast_Score=149, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 82562; Mature: 82431

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFTKQTITEVISKEERPIPAAILAKKVLEKIPTLNKTDVYKLIDLLIQENTIKKLENN
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHCCC
RLVIGYLDYEFDHEIKQGIITINSKGDGFIKEDNTEIEYYVNKKYLNGALKKDSVKFVKL
EEEEEEECCCCCCHHCCCEEEEECCCCCCEECCCCEEEEEEEHHHHCCCCCCCCEEEEEE
KKEPKNNLQDAAVIEIVGHAKDHYVGQFITLPNGGYYIFVDDPLFYLNINLKDTTGLVNG
ECCCCCCCCHHHHEEEECCCCCCCCEEEEECCCCCEEEEECCCEEEEEEEEECCCCCCCH
HKILFKIISQTTKDAIAELVHIIGHKNDVGSDVLSIVYDNGIDPTFDPQVVDLASKLEFY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
VDEHQNKIRRSIIDREIISIDPVGSKDIDDAVYVKKLNDQRYFLGISIADVSFYVQPNTI
HHHHHHHHHHHHHCCHHEEECCCCCCCCCCHHEEEECCCCEEEEEEEEEEEEEEECCCCE
LDADAFKRGTSTYLVDRVIPMLPHNISNNICSLNEGEFRMCITCDMVIDKDGKICKDVYP
ECHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHH
AIMKNYRQMSYDEVNDFYEGKSRFESATLTMKEMLLEAKELHHILRNKKIKDGYVDFDIK
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
EPKIILDETGVPIDIKIYERKTAQMMVEDFMIAANEAVTMFAEEHMDKTLKEFNLEMPFI
CCEEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEE
YRVHDKPSIINLQKFEIEAKKLSFNISHDFENIQPNTISNLKMNDNHVNLPLISKLLLRS
EEECCCCCEEEEEEEEEEEEEEEEEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHH
MAKASYEIINTGHFGLASDNYTHFTSPIRRYPDLIVHRLLMFIFDSQSYTDKQRVELVNK
HHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LKLITEESNKNEIIAVKTERDVNAAKFAEYMNLHIGKEFIGVVTTVSSFGVFVELENTIE
HHHEEECCCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCEEEEEEHHHHH
GLIRIKNLKDDFYDFIPENMTLVGQKRKKIITVGNKVRVRVIEANKLTRKIDFELVAQ
HHHHHHCCCHHHHHHCCCCEEEEECCCCEEEEECCEEEEEEEECCCCCEEECEEEECC
>Mature Secondary Structure 
SDFTKQTITEVISKEERPIPAAILAKKVLEKIPTLNKTDVYKLIDLLIQENTIKKLENN
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHCCC
RLVIGYLDYEFDHEIKQGIITINSKGDGFIKEDNTEIEYYVNKKYLNGALKKDSVKFVKL
EEEEEEECCCCCCHHCCCEEEEECCCCCCEECCCCEEEEEEEHHHHCCCCCCCCEEEEEE
KKEPKNNLQDAAVIEIVGHAKDHYVGQFITLPNGGYYIFVDDPLFYLNINLKDTTGLVNG
ECCCCCCCCHHHHEEEECCCCCCCCEEEEECCCCCEEEEECCCEEEEEEEEECCCCCCCH
HKILFKIISQTTKDAIAELVHIIGHKNDVGSDVLSIVYDNGIDPTFDPQVVDLASKLEFY
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
VDEHQNKIRRSIIDREIISIDPVGSKDIDDAVYVKKLNDQRYFLGISIADVSFYVQPNTI
HHHHHHHHHHHHHCCHHEEECCCCCCCCCCHHEEEECCCCEEEEEEEEEEEEEEECCCCE
LDADAFKRGTSTYLVDRVIPMLPHNISNNICSLNEGEFRMCITCDMVIDKDGKICKDVYP
ECHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHH
AIMKNYRQMSYDEVNDFYEGKSRFESATLTMKEMLLEAKELHHILRNKKIKDGYVDFDIK
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
EPKIILDETGVPIDIKIYERKTAQMMVEDFMIAANEAVTMFAEEHMDKTLKEFNLEMPFI
CCEEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEE
YRVHDKPSIINLQKFEIEAKKLSFNISHDFENIQPNTISNLKMNDNHVNLPLISKLLLRS
EEECCCCCEEEEEEEEEEEEEEEEEECCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHH
MAKASYEIINTGHFGLASDNYTHFTSPIRRYPDLIVHRLLMFIFDSQSYTDKQRVELVNK
HHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LKLITEESNKNEIIAVKTERDVNAAKFAEYMNLHIGKEFIGVVTTVSSFGVFVELENTIE
HHHEEECCCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCEEEEEEHHHHH
GLIRIKNLKDDFYDFIPENMTLVGQKRKKIITVGNKVRVRVIEANKLTRKIDFELVAQ
HHHHHHCCCHHHHHHCCCCEEEEECCCCEEEEECCEEEEEEEECCCCCEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11048724 [H]