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The map label for this gene is cysS

Identifier: 170761946

GI number: 170761946

Start: 162492

End: 163802

Strand: Direct

Name: cysS

Synonym: UPA3_0129

Alternate gene names: 170761946

Gene position: 162492-163802 (Clockwise)

Preceding gene: 170762155

Following gene: 170761850

Centisome position: 21.62

GC content: 23.72

Gene sequence:

>1311_bases
ATGAAATTATATGATTCTTATTCTAATCAATTAGTAGAAATTAATGATGAATTAATTTCAATTTATAATTGTGGACCAAC
CGTTTATAATCATATCCATATTGGCAATGCTCGGCCTTTAATTACTATGGACGTGTTATATCGTTTTTTAAAAAAACATA
ATATCAAAACTAAATATGTTTTAAATATTACTGATATTGATGACAAAATCATTAATTATGCTCTAGCTAATAACCTAAAA
GAATTAGAGGTTAGTGAATATTATTTTAATGAATATTTAAAAATTAAAAAAGCTTTAAATACACTAGAAATGATTAATCC
TAAAGTATCAACACATATGGATAAAATTATTGATTATATCCAAAAATTGATTGATAAACAAGCAGGTTATTTTATTGGTG
ATGATGTTTATTTTGATACAAAAAAAGCTTTAAATTACGGACAATTATCGAAACGTGATTTAGAAAATGATATTGTTGGT
ATGCGTATTGAAAGCGCAGCTAATAAACACAATCCTAATGATTTTATTTTATGAAAGAAAACAAATAAAGGTATTATGTG
AAATACACCTTGAGGAATCGGTCGCCCAGGTTGGCATTCTGAATGCTCATGTTTGATCAACACTTATATTGGTGAACAAG
TTAGTATTCATGGTGGTGGAATTGATTTAAAATTTCCCCACCATGAAAATGAAAATGCTCAAAATCAAGTTTTATATAAT
AAAAATTTAGCAAAAGTATGAATGCATTTTGGATTAGTTAATATTAATAATGAGAAAATGTCAAAATCTTTAAATAATTT
TATTTTAGTAAAAGATTTATTAGCTGAATACGATTATCAAGTTGTGCGTTGGTTTTTTTATCAAGCAGATTATAAGCAAC
CAATTAAATTTTCGCATGAAATCATGAAGCAGAACGAAAAAGAAATTCTTAAAATTAAAAATGCTATTTATAACGCAAAA
AACTATTTATACTTCAATAATCAACTAAAATCATTAACACAAATTGATCATTTTGAGCTTTTTGATGAACGCATTAATGA
TGATTTAGATTTTGTAGGTATTGTTGATCTAATTCATATTAGTGTTAAAAAAATAAATATTTTAATTAAAGAAAATAAGG
ATATGAATGAATTAAAACTGAATTTAACTCAATTATTATATATGTTAGATATATTGGGTATTAATTTTGTTGATTTGCAT
AATGATGAGAATTTAGCATTATTAAATACTTGAAAAAATTACGTTGATAAAAAAGATTATGTTAAAGCTGATGAATTAAG
AAAACAATTAATTAATATAGGAATTTTATAA

Upstream 100 bases:

>100_bases
AATTTAATTAAAAACATCATTATTAGTTTTATATCATTAACTATATTAAAAATTTTTGCAGATAAAAAAACGATTATTAC
ATATTAACAAGGAATAATTT

Downstream 100 bases:

>100_bases
AATGAATTATAATTTTGGCAAAAAAGCATTATTAGATGCAATTGGTAACAAACAATCAATTTCAAAAGTGTATTTATTAT
CAAAAAATTATGAGTTAATT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MKLYDSYSNQLVEINDELISIYNCGPTVYNHIHIGNARPLITMDVLYRFLKKHNIKTKYVLNITDIDDKIINYALANNLK
ELEVSEYYFNEYLKIKKALNTLEMINPKVSTHMDKIIDYIQKLIDKQAGYFIGDDVYFDTKKALNYGQLSKRDLENDIVG
MRIESAANKHNPNDFILWKKTNKGIMWNTPWGIGRPGWHSECSCLINTYIGEQVSIHGGGIDLKFPHHENENAQNQVLYN
KNLAKVWMHFGLVNINNEKMSKSLNNFILVKDLLAEYDYQVVRWFFYQADYKQPIKFSHEIMKQNEKEILKIKNAIYNAK
NYLYFNNQLKSLTQIDHFELFDERINDDLDFVGIVDLIHISVKKINILIKENKDMNELKLNLTQLLYMLDILGINFVDLH
NDENLALLNTWKNYVDKKDYVKADELRKQLINIGIL

Sequences:

>Translated_436_residues
MKLYDSYSNQLVEINDELISIYNCGPTVYNHIHIGNARPLITMDVLYRFLKKHNIKTKYVLNITDIDDKIINYALANNLK
ELEVSEYYFNEYLKIKKALNTLEMINPKVSTHMDKIIDYIQKLIDKQAGYFIGDDVYFDTKKALNYGQLSKRDLENDIVG
MRIESAANKHNPNDFIL*KKTNKGIM*NTP*GIGRPGWHSECSCLINTYIGEQVSIHGGGIDLKFPHHENENAQNQVLYN
KNLAKV*MHFGLVNINNEKMSKSLNNFILVKDLLAEYDYQVVRWFFYQADYKQPIKFSHEIMKQNEKEILKIKNAIYNAK
NYLYFNNQLKSLTQIDHFELFDERINDDLDFVGIVDLIHISVKKINILIKENKDMNELKLNLTQLLYMLDILGINFVDLH
NDENLALLNT*KNYVDKKDYVKADELRKQLINIGIL
>Mature_436_residues
MKLYDSYSNQLVEINDELISIYNCGPTVYNHIHIGNARPLITMDVLYRFLKKHNIKTKYVLNITDIDDKIINYALANNLK
ELEVSEYYFNEYLKIKKALNTLEMINPKVSTHMDKIIDYIQKLIDKQAGYFIGDDVYFDTKKALNYGQLSKRDLENDIVG
MRIESAANKHNPNDFIL*KKTNKGIM*NTP*GIGRPGWHSECSCLINTYIGEQVSIHGGGIDLKFPHHENENAQNQVLYN
KNLAKV*MHFGLVNINNEKMSKSLNNFILVKDLLAEYDYQVVRWFFYQADYKQPIKFSHEIMKQNEKEILKIKNAIYNAK
NYLYFNNQLKSLTQIDHFELFDERINDDLDFVGIVDLIHISVKKINILIKENKDMNELKLNLTQLLYMLDILGINFVDLH
NDENLALLNT*KNYVDKKDYVKADELRKQLINIGIL

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=379, Percent_Identity=31.9261213720317, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI62240992, Length=258, Percent_Identity=32.1705426356589, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI303304987, Length=258, Percent_Identity=32.1705426356589, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI21269877, Length=258, Percent_Identity=32.1705426356589, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI10835051, Length=258, Percent_Identity=32.1705426356589, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1786737, Length=438, Percent_Identity=33.1050228310502, Blast_Score=217, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI17509795, Length=244, Percent_Identity=33.1967213114754, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17509797, Length=244, Percent_Identity=33.1967213114754, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324082, Length=223, Percent_Identity=36.322869955157, Blast_Score=123, Evalue=5e-29,
Organism=Drosophila melanogaster, GI19922218, Length=402, Percent_Identity=32.3383084577114, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI19922364, Length=258, Percent_Identity=30.6201550387597, Blast_Score=121, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 50276; Mature: 50276

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYDSYSNQLVEINDELISIYNCGPTVYNHIHIGNARPLITMDVLYRFLKKHNIKTKYV
CCCCCCCCCCEEEECCCEEEEEECCCHHEEEEEECCCCCEEEHHHHHHHHHHCCCCEEEE
LNITDIDDKIINYALANNLKELEVSEYYFNEYLKIKKALNTLEMINPKVSTHMDKIIDYI
EEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QKLIDKQAGYFIGDDVYFDTKKALNYGQLSKRDLENDIVGMRIESAANKHNPNDFILKKT
HHHHHHCCCEEECCCEEECHHHHCCCCCCCHHHHCCCCCCEEEHHHCCCCCCCCEEEEEC
NKGIMNTPGIGRPGWHSECSCLINTYIGEQVSIHGGGIDLKFPHHENENAQNQVLYNKNL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCEEEECCCCCCCCCCCCEEECCCH
AKVMHFGLVNINNEKMSKSLNNFILVKDLLAEYDYQVVRWFFYQADYKQPIKFSHEIMKQ
HHHHHHCEEEECHHHHHHHHHCEEHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHC
NEKEILKIKNAIYNAKNYLYFNNQLKSLTQIDHFELFDERINDDLDFVGIVDLIHISVKK
CHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEE
INILIKENKDMNELKLNLTQLLYMLDILGINFVDLHNDENLALLNTKNYVDKKDYVKADE
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCHHCCCHHH
LRKQLINIGIL
HHHHHHHCCCC
>Mature Secondary Structure
MKLYDSYSNQLVEINDELISIYNCGPTVYNHIHIGNARPLITMDVLYRFLKKHNIKTKYV
CCCCCCCCCCEEEECCCEEEEEECCCHHEEEEEECCCCCEEEHHHHHHHHHHCCCCEEEE
LNITDIDDKIINYALANNLKELEVSEYYFNEYLKIKKALNTLEMINPKVSTHMDKIIDYI
EEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QKLIDKQAGYFIGDDVYFDTKKALNYGQLSKRDLENDIVGMRIESAANKHNPNDFILKKT
HHHHHHCCCEEECCCEEECHHHHCCCCCCCHHHHCCCCCCEEEHHHCCCCCCCCEEEEEC
NKGIMNTPGIGRPGWHSECSCLINTYIGEQVSIHGGGIDLKFPHHENENAQNQVLYNKNL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCEEEECCCCCCCCCCCCEEECCCH
AKVMHFGLVNINNEKMSKSLNNFILVKDLLAEYDYQVVRWFFYQADYKQPIKFSHEIMKQ
HHHHHHCEEEECHHHHHHHHHCEEHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHC
NEKEILKIKNAIYNAKNYLYFNNQLKSLTQIDHFELFDERINDDLDFVGIVDLIHISVKK
CHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEE
INILIKENKDMNELKLNLTQLLYMLDILGINFVDLHNDENLALLNTKNYVDKKDYVKADE
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCCCCCHHCCCHHH
LRKQLINIGIL
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11048724 [H]