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The map label for this gene is yncB [H]

Identifier: 170682763

GI number: 170682763

Start: 1731172

End: 1732209

Strand: Reverse

Name: yncB [H]

Synonym: EcSMS35_1723

Alternate gene names: 170682763

Gene position: 1732209-1731172 (Counterclockwise)

Preceding gene: 170681585

Following gene: 170681762

Centisome position: 34.18

GC content: 52.89

Gene sequence:

>1038_bases
ATGGGGCAACAAAAGCAGCGTAACCGCCGTTGGGTTCTGGCCTCGCGTCCGCATGGCGCGCCGGTTCCGGAGAATTTCCG
TCTTGAAGAAGATGATGTCGCCACACCGGGTGAAGGTCAGGTGTTACTGCGCACAGTTTATTTGTCACTGGACCCGTATA
TGCGTGGACGTATGAGCGATGAGCCATCTTATTCACCGCCGGTTGATATTGGCGGCGTGATGGTCGGCGGTACGGTGAGC
CGTGTCGTGGAGTCGAATCATCCTGATTATCAGCCTGGCGACTGGGTGCTGGGCTACAGTGGATGGCAGGACTATGACAT
ATCCAGTGGTGATGATCTGGTGAAACTTGGCGATCATCCGCAAAATCCATCGTGGTCGCTGGGTGTGCTGGGGATGCCAG
GCTTTACCGCTTATATGGGGCTGCTGGATATCGGTCAGCCTAAAGAGGGCGAAACGCTGGTGGTAGCTGCGGCGACAGGA
CCAGTGGGGGCGACGGTGGGGCAAATCGGCAAACTTAAAGGTTGCAGGGTGGTGGGGGTTGCCGGTGGCGCGGAAAAATG
CCGCCATGCCACCGAAGTGCTGGGTTTTGATGTTTGCCTTGACCATCACGCGGATGATTTTGCCGAACAACTGGCGAAAG
CGTGCCCAAAAGGTATTGATATCTATTATGAAAACGTTGGTGGTAAGGTATTTGATGCGGTGCTACCGTTACTCAATACA
TCTGCGCGCATTCCCGTCTGCGGCTTAGTGAGCAGCTATAACGCTACAGAGCTACCACCCGGTCCGGATCGTTTACCCCT
GTTGATGGCTACGGTGCTGAAAAAACGCATTCGATTACAAGGGTTTATTATTGGTCAGGATTATGGTCACCGTATCCATG
AGTTTCAGCAGGAGATGGGACAATGGGTGAAAGAGGGGAAAATTCACTATCGTGAACAAATTACCAACGGTTTGGAGAAC
GCCCCACAGACGTTTATTGGCCTGCTGAACGGCAAAAACTTCGGTAAAGTTGTTATTCGCGTCGCGGATGATGATTAA

Upstream 100 bases:

>100_bases
TTATTGCGTGTTGCAGAGGGGATGTGACGGCTGCAAACAAAACCAATCCCGTGAGCCTGCTACTATTGATGGATTCATGC
CAAAAGCACAGGAGAGCACT

Downstream 100 bases:

>100_bases
AGATACGACGGCGGCATAAAGCCGCCATAAAAATCCAGGCAAAAATCTTTTTTCCAGCTTTAATTAACTTACCACTTCTC
TGTTCTGTAGCTAATAACAA

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSDEPSYSPPVDIGGVMVGGTVS
RVVESNHPDYQPGDWVLGYSGWQDYDISSGDDLVKLGDHPQNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATG
PVGATVGQIGKLKGCRVVGVAGGAEKCRHATEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNT
SARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIGQDYGHRIHEFQQEMGQWVKEGKIHYREQITNGLEN
APQTFIGLLNGKNFGKVVIRVADDD

Sequences:

>Translated_345_residues
MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSDEPSYSPPVDIGGVMVGGTVS
RVVESNHPDYQPGDWVLGYSGWQDYDISSGDDLVKLGDHPQNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATG
PVGATVGQIGKLKGCRVVGVAGGAEKCRHATEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNT
SARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIGQDYGHRIHEFQQEMGQWVKEGKIHYREQITNGLEN
APQTFIGLLNGKNFGKVVIRVADDD
>Mature_344_residues
GQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSDEPSYSPPVDIGGVMVGGTVSR
VVESNHPDYQPGDWVLGYSGWQDYDISSGDDLVKLGDHPQNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATGP
VGATVGQIGKLKGCRVVGVAGGAEKCRHATEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNTS
ARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIGQDYGHRIHEFQQEMGQWVKEGKIHYREQITNGLENA
PQTFIGLLNGKNFGKVVIRVADDD

Specific function: Unknown

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226246682, Length=352, Percent_Identity=38.3522727272727, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI226246680, Length=352, Percent_Identity=38.3522727272727, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI22748929, Length=352, Percent_Identity=38.3522727272727, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI226059159, Length=338, Percent_Identity=37.8698224852071, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI226059133, Length=338, Percent_Identity=37.8698224852071, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI226056130, Length=310, Percent_Identity=36.4516129032258, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI28557745, Length=342, Percent_Identity=28.6549707602339, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI194239674, Length=239, Percent_Identity=28.8702928870293, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI13236495, Length=239, Percent_Identity=28.8702928870293, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI226510941, Length=345, Percent_Identity=97.6811594202899, Blast_Score=692, Evalue=0.0,
Organism=Caenorhabditis elegans, GI133901712, Length=360, Percent_Identity=32.5, Blast_Score=170, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI133901710, Length=360, Percent_Identity=32.5, Blast_Score=170, Evalue=9e-43,
Organism=Saccharomyces cerevisiae, GI6323504, Length=371, Percent_Identity=26.6846361185984, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37562; Mature: 37431

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSD
CCCCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCEEEEEEEECCCHHHHCCCCC
EPSYSPPVDIGGVMVGGTVSRVVESNHPDYQPGDWVLGYSGWQDYDISSGDDLVKLGDHP
CCCCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCC
QNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATGPVGATVGQIGKLKGCRVVGV
CCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEE
AGGAEKCRHATEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNT
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCC
SARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIGQDYGHRIHEFQQEMG
CCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHHHHHH
QWVKEGKIHYREQITNGLENAPQTFIGLLNGKNFGKVVIRVADDD
HHHHHCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEEECCC
>Mature Secondary Structure 
GQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSD
CCCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCEEEEEEEECCCHHHHCCCCC
EPSYSPPVDIGGVMVGGTVSRVVESNHPDYQPGDWVLGYSGWQDYDISSGDDLVKLGDHP
CCCCCCCCCCCCEEECCHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECCCC
QNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATGPVGATVGQIGKLKGCRVVGV
CCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEE
AGGAEKCRHATEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNT
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCC
SARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIGQDYGHRIHEFQQEMG
CCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECHHHHHHHHHHHHHH
QWVKEGKIHYREQITNGLENAPQTFIGLLNGKNFGKVVIRVADDD
HHHHHCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]