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The map label for this gene is ydcR [H]

Identifier: 170682466

GI number: 170682466

Start: 1739827

End: 1741233

Strand: Reverse

Name: ydcR [H]

Synonym: EcSMS35_1735

Alternate gene names: 170682466

Gene position: 1741233-1739827 (Counterclockwise)

Preceding gene: 170682851

Following gene: 170681458

Centisome position: 34.35

GC content: 50.68

Gene sequence:

>1407_bases
ATGAAAAAATACCAGCAGCTTGCAGAACAATTACGCGAGCAGATTGCGTCGGGTATCTGGCAACCCGGAGATCGTTTGCC
TTCGTTGCGTGACCAGGTGGCACTTTCTGGCATGAGCTTTATGACCGTGAGCCATGCCTATCAGTTGCTCGAAAGTCAGG
GATATATTATCGCACGACCGCAGTCGGGTTATTACGTTGCGCCACAGGCAATAAAAATGCCGAAAGCGCCAGTCATTCCA
GTCACTCGAGATGAAGCAGTCGATATCAACACTTATATTTTTGATATGTTGCAGGCCAGTCGCGATCCGTCGGTCGTTCC
GTTTGCCTCGGCCTTTCCCGACCCGCGACTTTTCCCCCTCCAACAACTAAACCGCTCGCTGGCGCAGGTAAGCAAAACCG
CCACAGCGATGAGCGTGATTGAAAACTTACCGCCAGGAAACGCAGAACTGCGTCAGGCTATTGCTCGTCGCTATGCCTTA
CAGGGCATCACTATTTCTCCAGATGAAATTGCCATTACCGCCGGGGCGTTAGAGGCATTAAACCTCAGTTTGCAAGTGGT
AACTGAACCGGGCGATTGGGTGATAGTAGAGAATCCTTGTTTCTACGGCGCTTTGCAGGCGCTGGAGCGGTTACGGCTGA
AGGCGTTATCGGTGGCGACGGACGTTAAAGAAGGGATCGATCTTCAGGCGCTGGAACTGGCGTTGCAGGAGTATCCGGTG
AAAGCGTGCTGGCTGATGACTAATAGCCAGAATCCACTCGGATTTACCTTAACACCGCAAAAAAAAGCACAACTGGTGGC
GTTGCTCAATCAGTACAACGTAACGCTGATTGAAGATGACGTTTACAGCGAACTTTATTTTGGACGGGAAAAACCGCTGC
CTGCGAAAGCGTGGGATCACCACGATGGTGTTTTGCATTGCTCTTCGTTTTCGAAATGTCTGGTGCCTGGTTTTCGTATT
GGTTGGGTCGCCGCCGGAAAACATGCACGTAAAATTCAACGCTTGCAGTTGATGAGTACGCTTTCCACCAGCTCACCGAT
GCAGCTTGCGCTGGTGGATTACCTTTCTACTCGCCGATACGATGCTCATCTTCGTCGTCTGCGTCGCCAGCTTGCGGAAC
GTAAACAACGCGCCTGGCAGGCTTTGCTGCGTTATCTGCCTGCGGAAGTCAAAATTCATCACAATGACAGCGGTTATTTT
CTCTGGCTGGAGCTCCCCGAGCCGTTAGATGCAGGAGAATTAAGCCTGGTGGCACTGACGCATCATATCAGTATTGCGCC
GGGTAAAATGTTTTCTACCGGTGAAAACTGGTCACGTTTTTTTCGTTTTAATACCGCGTGGCAGTGGGGAGAACGTGAAG
AACAGGCGGTAAAACAATTAGGCAAACTTATTCAAGAACGGCTGTAA

Upstream 100 bases:

>100_bases
GTTATCACTGGTGATGGTTTGATAACAGTTAATGAAAAGTTGTCATTTTTAACAACTGATATAGACTGCCGAATCACCTG
CACATAATAACGATTCGATA

Downstream 100 bases:

>100_bases
TAGCGTTTAATTTAATTCCTCTCAGGATGGGTAATATGAATTTCGAATAGCAGTCATATTTCCTAACTCCTTGTCTATAC
TCCAGAATATAACCTTACAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSGYYVAPQAIKMPKAPVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
QGITISPDEIAITAGALEALNLSLQVVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQEYPV
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDHHDGVLHCSSFSKCLVPGFRI
GWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYF
LWLELPEPLDAGELSLVALTHHISIAPGKMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL

Sequences:

>Translated_468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSGYYVAPQAIKMPKAPVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
QGITISPDEIAITAGALEALNLSLQVVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQEYPV
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDHHDGVLHCSSFSKCLVPGFRI
GWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYF
LWLELPEPLDAGELSLVALTHHISIAPGKMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL
>Mature_468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSGYYVAPQAIKMPKAPVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
QGITISPDEIAITAGALEALNLSLQVVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQEYPV
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDHHDGVLHCSSFSKCLVPGFRI
GWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYF
LWLELPEPLDAGELSLVALTHHISIAPGKMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=401, Percent_Identity=25.6857855361596, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI33469970, Length=401, Percent_Identity=25.6857855361596, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI4507369, Length=236, Percent_Identity=24.5762711864407, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1787710, Length=468, Percent_Identity=99.1452991452991, Blast_Score=954, Evalue=0.0,
Organism=Escherichia coli, GI1790797, Length=466, Percent_Identity=34.7639484978541, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI1788722, Length=312, Percent_Identity=25.6410256410256, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17567663, Length=184, Percent_Identity=25, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356535, Length=331, Percent_Identity=23.8670694864048, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI18859735, Length=224, Percent_Identity=27.2321428571429, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52802; Mature: 52802

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARP
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECC
QSGYYVAPQAIKMPKAPVIPVTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPL
CCCEEECCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEHHCCCCCCCCCH
QQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYALQGITISPDEIAITAGALEAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEHHHHHHH
NLSLQVVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQEYPV
CEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDH
EEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCCCCCCC
HDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRY
CCCEEEECCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYFLWLELPEPLDAGELSLVALT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCEEEEEEE
HHISIAPGKMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL
EEEEECCCCCCCCCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARP
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECC
QSGYYVAPQAIKMPKAPVIPVTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPL
CCCEEECCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEHHCCCCCCCCCH
QQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYALQGITISPDEIAITAGALEAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEHHHHHHH
NLSLQVVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQEYPV
CEEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDH
EEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCCCCCCC
HDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRY
CCCEEEECCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYFLWLELPEPLDAGELSLVALT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCEEEEEEE
HHISIAPGKMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQERL
EEEEECCCCCCCCCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]