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The map label for this gene is bcsB [H]

Identifier: 170681414

GI number: 170681414

Start: 3914806

End: 3917115

Strand: Reverse

Name: bcsB [H]

Synonym: EcSMS35_3841

Alternate gene names: 170681414

Gene position: 3917115-3914806 (Counterclockwise)

Preceding gene: 170679974

Following gene: 170683128

Centisome position: 77.29

GC content: 55.5

Gene sequence:

>2310_bases
GTGGCTATGGGGATGAGTGCGTTCCCCTCTTTCATGACGCAGGCGACGCCAGCAACGCAACCACTGATCAATGCTGAGCC
AGCTGTAGCCGCCCAGACGGAACAAAATCCGCAGGTGGGGCAAGTGATGCCGGGCGTGCAGGGCGCTGATGCCCCCATCG
TGGCGCAGAACGGTCCTTCGCGTGATGTGAAGCTGACCTTTGCGCAAATTGCGCCGCCGCCGGGCAGCATGGTGCTACGT
GGCATTAACCCGAACGGCAGCATTGAGTTTGGTATGCGCAGTGATGAAGTGGTGACGAAGGCGATGCTCAACCTCGAATA
CACGCCATCGCCATCGTTACTGCCTGTCCAGTCGCAGTTAAAGGTTTATCTCAATGATGAACTGATGGGCGTGCTGCCAG
TGACCAAAGAACAGTTGGGTAAAAAAACGCTGGCGCAAATGCCCATTAACCCACTGTTTATTACCGACTTCAACCGTGTG
CGGCTGGAGTTTGTCGGCCATTATCAGGACGTGTGCGAAAACCCGGCCAGCACCACGCTTTGGCTGGATGTTGGGCGGAG
CAGTGGACTGGATTTGACCTATCAGACCCTGAATGTGAAGAATGACCTGTCACACTTCCCGGTGCCATTCTTTGACCCGC
GTGATAACCGCACCAACACCTTGCCGATGGTCTTTGCGGGTGCGCCGGATGTTGGGCTGCAACAAGCATCTGCCATTGTC
GCCTCGTGGTTTGGTTCGCGTTCTGGCTGGCGTGGGCAGAACTTCCCGGTGCTCTATAACCAACTGCCGGATCGCAATGC
CATTGTTTTTGCCACTAATGACAAACGGCCGGACTTCCTGCGCGATCATCCGGCGGTAAAAGCCCCGGTGATTGAAATGA
TCAACCATCCGCAGAATCCTTACGTCAAACTGCTGGTGGTCTTTGGTCGTGACGACAAAGACCTGTTGCAGGCAGCGAAA
GGTATCGCTCAGGGTAACATTCTGTTCCGTGGTGAAAGCGTGGTAGTGAATGAAGTGAAACCGCTGCTACCGCGTAAGCC
GTACGATGCGCCGAACTGGGTGCGTACCGATCGTCCGGTCACCTTTGGTGAACTGAAAACCTATGAAGAACAGTTACAAT
CCAGCGGTCTTGAGCCAGCAGCGATTAACGTTTCGCTAAATCTGCCGCCGGATCTCTACCTGATGCGCAGTACCGGCATT
GATATGGATATCAACTATCGCTACACCATGCCGCCGGTGAAAGACAGTTCGCGGATGGATATCAGCCTGAATAACCAGTT
CCTGCAATCCTTCAACCTGAGCAGTAAACAGGAGGCGAACCGCCTGCTGCTGCGGATTCCGGTATTACAAGGTTTGCTGG
ATGGCAAAACGGATGTCTCTATTCCGGCGCTGAAACTGGGCGCGACCAACCAGTTGCGGTTCGACTTTGAGTATATGAAC
CCGATGCCGGGCGGTTCGGTGGATAACTGTATTACCTTCCAGCCGGTGCAGAATCATGTGGTGATTGGTGACGACTCCAC
CATCGACTTCTCGAAGTATTACCACTTCATCCCGATGCCGGATCTACGCGCCTTTGCTAACGCGGGCTTCCCGTTCAGCC
GGATGGCGGATCTGTCACAAACCATCACCGTGATGCCGAAAGCGCCTAACGAAGCACAGATGGAAACCTTGCTGAATACC
GTTGGCTTTATCGGTGCGCAGACGGGCTTCCCGGCGATTAACCTGACGGTGACCGATGATGGCAGCACCATTCAGGGCAA
AGATGCCGACATCATGATCGTCGGTGGTATCCCGGACAAACTGAAAGACGACAAGCAGATCGACCTGTTGGTGCAGGCGA
CCGAAAGCTGGGTGAAAACGCCGATGCGCCAGACCCCGTTCCCCGGCATTGTACCGGACGAGAGCGATCGCGCGGCAGAA
ACTCAGTCAACGCTGACCTCTTCCGGTGCGATGGCAGCGGTGATTGGCTTCCAGTCGCCGTATAACGACCAGCGTAGCGT
GATTGCGCTGCTGGCAGATAGCCCACGCGGTTATGAAATGCTTAACGATGCGGTGAACGATAGCGGCAAACGCGCCACCA
TGTTCGGTTCGGTCGCGGTGATCCGCGAGTCCGGTATCAATAGCCTGCGTGTTGGCGACGTCTATTACGTTGGCCATCTG
CCGTGGTTCGAACGCTTATGGTATGCCCTGGCAAACCATCCGATTCTGCTGGCGGTGCTGGCGGCAATCAGCGTCGTGCT
GCTGGCATGGGTACTGTGGCGTTTGCTGCGTATTATCAGCCGTCGTCGTCTTAACCCGGATAACGAGTAA

Upstream 100 bases:

>100_bases
CGCCGCCCGGAGCGGAGCGAAACGGCACAACCATCGGATCAGGCTTTGGCTCAACAATGATGATAACGCGATGAAAAGAA
AACTATTCTGGATTTGTGCA

Downstream 100 bases:

>100_bases
TTGAAGATGAATGTGTTGCGTAGTGGACTCGTGACGATGCTGCTGCTGGCTGCCTTTAGTGTTCAGGCAGCCTGCAACTG
GCCTGCCTGGGAGCAATTCA

Product: cellulose synthase regulator protein

Products: NA

Alternate protein names: Cellulose synthase regulatory subunit [H]

Number of amino acids: Translated: 769; Mature: 768

Protein sequence:

>769_residues
MAMGMSAFPSFMTQATPATQPLINAEPAVAAQTEQNPQVGQVMPGVQGADAPIVAQNGPSRDVKLTFAQIAPPPGSMVLR
GINPNGSIEFGMRSDEVVTKAMLNLEYTPSPSLLPVQSQLKVYLNDELMGVLPVTKEQLGKKTLAQMPINPLFITDFNRV
RLEFVGHYQDVCENPASTTLWLDVGRSSGLDLTYQTLNVKNDLSHFPVPFFDPRDNRTNTLPMVFAGAPDVGLQQASAIV
ASWFGSRSGWRGQNFPVLYNQLPDRNAIVFATNDKRPDFLRDHPAVKAPVIEMINHPQNPYVKLLVVFGRDDKDLLQAAK
GIAQGNILFRGESVVVNEVKPLLPRKPYDAPNWVRTDRPVTFGELKTYEEQLQSSGLEPAAINVSLNLPPDLYLMRSTGI
DMDINYRYTMPPVKDSSRMDISLNNQFLQSFNLSSKQEANRLLLRIPVLQGLLDGKTDVSIPALKLGATNQLRFDFEYMN
PMPGGSVDNCITFQPVQNHVVIGDDSTIDFSKYYHFIPMPDLRAFANAGFPFSRMADLSQTITVMPKAPNEAQMETLLNT
VGFIGAQTGFPAINLTVTDDGSTIQGKDADIMIVGGIPDKLKDDKQIDLLVQATESWVKTPMRQTPFPGIVPDESDRAAE
TQSTLTSSGAMAAVIGFQSPYNDQRSVIALLADSPRGYEMLNDAVNDSGKRATMFGSVAVIRESGINSLRVGDVYYVGHL
PWFERLWYALANHPILLAVLAAISVVLLAWVLWRLLRIISRRRLNPDNE

Sequences:

>Translated_769_residues
MAMGMSAFPSFMTQATPATQPLINAEPAVAAQTEQNPQVGQVMPGVQGADAPIVAQNGPSRDVKLTFAQIAPPPGSMVLR
GINPNGSIEFGMRSDEVVTKAMLNLEYTPSPSLLPVQSQLKVYLNDELMGVLPVTKEQLGKKTLAQMPINPLFITDFNRV
RLEFVGHYQDVCENPASTTLWLDVGRSSGLDLTYQTLNVKNDLSHFPVPFFDPRDNRTNTLPMVFAGAPDVGLQQASAIV
ASWFGSRSGWRGQNFPVLYNQLPDRNAIVFATNDKRPDFLRDHPAVKAPVIEMINHPQNPYVKLLVVFGRDDKDLLQAAK
GIAQGNILFRGESVVVNEVKPLLPRKPYDAPNWVRTDRPVTFGELKTYEEQLQSSGLEPAAINVSLNLPPDLYLMRSTGI
DMDINYRYTMPPVKDSSRMDISLNNQFLQSFNLSSKQEANRLLLRIPVLQGLLDGKTDVSIPALKLGATNQLRFDFEYMN
PMPGGSVDNCITFQPVQNHVVIGDDSTIDFSKYYHFIPMPDLRAFANAGFPFSRMADLSQTITVMPKAPNEAQMETLLNT
VGFIGAQTGFPAINLTVTDDGSTIQGKDADIMIVGGIPDKLKDDKQIDLLVQATESWVKTPMRQTPFPGIVPDESDRAAE
TQSTLTSSGAMAAVIGFQSPYNDQRSVIALLADSPRGYEMLNDAVNDSGKRATMFGSVAVIRESGINSLRVGDVYYVGHL
PWFERLWYALANHPILLAVLAAISVVLLAWVLWRLLRIISRRRLNPDNE
>Mature_768_residues
AMGMSAFPSFMTQATPATQPLINAEPAVAAQTEQNPQVGQVMPGVQGADAPIVAQNGPSRDVKLTFAQIAPPPGSMVLRG
INPNGSIEFGMRSDEVVTKAMLNLEYTPSPSLLPVQSQLKVYLNDELMGVLPVTKEQLGKKTLAQMPINPLFITDFNRVR
LEFVGHYQDVCENPASTTLWLDVGRSSGLDLTYQTLNVKNDLSHFPVPFFDPRDNRTNTLPMVFAGAPDVGLQQASAIVA
SWFGSRSGWRGQNFPVLYNQLPDRNAIVFATNDKRPDFLRDHPAVKAPVIEMINHPQNPYVKLLVVFGRDDKDLLQAAKG
IAQGNILFRGESVVVNEVKPLLPRKPYDAPNWVRTDRPVTFGELKTYEEQLQSSGLEPAAINVSLNLPPDLYLMRSTGID
MDINYRYTMPPVKDSSRMDISLNNQFLQSFNLSSKQEANRLLLRIPVLQGLLDGKTDVSIPALKLGATNQLRFDFEYMNP
MPGGSVDNCITFQPVQNHVVIGDDSTIDFSKYYHFIPMPDLRAFANAGFPFSRMADLSQTITVMPKAPNEAQMETLLNTV
GFIGAQTGFPAINLTVTDDGSTIQGKDADIMIVGGIPDKLKDDKQIDLLVQATESWVKTPMRQTPFPGIVPDESDRAAET
QSTLTSSGAMAAVIGFQSPYNDQRSVIALLADSPRGYEMLNDAVNDSGKRATMFGSVAVIRESGINSLRVGDVYYVGHLP
WFERLWYALANHPILLAVLAAISVVLLAWVLWRLLRIISRRRLNPDNE

Specific function: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass type I membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcsB/BcsB family [H]

Homologues:

Organism=Escherichia coli, GI1789952, Length=769, Percent_Identity=98.8296488946684, Blast_Score=1559, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003920
- InterPro:   IPR018513 [H]

Pfam domain/function: PF03170 BcsB [H]

EC number: NA

Molecular weight: Translated: 84820; Mature: 84689

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMGMSAFPSFMTQATPATQPLINAEPAVAAQTEQNPQVGQVMPGVQGADAPIVAQNGPS
CCCCCHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCCCCCCCEEECCCCC
RDVKLTFAQIAPPPGSMVLRGINPNGSIEFGMRSDEVVTKAMLNLEYTPSPSLLPVQSQL
CCEEEEEEEECCCCCCEEEEECCCCCCEEECCCCHHHHHHHHHEEEECCCCCEEECCCCE
KVYLNDELMGVLPVTKEQLGKKTLAQMPINPLFITDFNRVRLEFVGHYQDVCENPASTTL
EEEECCCEEEEECCCHHHHCHHHHHHCCCCEEEEECCCEEEEEEHHHHHHHHCCCCCEEE
WLDVGRSSGLDLTYQTLNVKNDLSHFPVPFFDPRDNRTNTLPMVFAGAPDVGLQQASAIV
EEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHH
ASWFGSRSGWRGQNFPVLYNQLPDRNAIVFATNDKRPDFLRDHPAVKAPVIEMINHPQNP
HHHHCCCCCCCCCCCCCCEECCCCCCEEEEEECCCCCCHHHCCCCCHHHHHHHHCCCCCC
YVKLLVVFGRDDKDLLQAAKGIAQGNILFRGESVVVNEVKPLLPRKPYDAPNWVRTDRPV
EEEEEEEECCCCHHHHHHHHCCCCCCEEEECCEEEEECHHHHCCCCCCCCCCCCCCCCCC
TFGELKTYEEQLQSSGLEPAAINVSLNLPPDLYLMRSTGIDMDINYRYTMPPVKDSSRMD
CHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCEEEEEEEECCCCCCCCEEE
ISLNNQFLQSFNLSSKQEANRLLLRIPVLQGLLDGKTDVSIPALKLGATNQLRFDFEYMN
EEECHHHHHHCCCCCHHHHCCEEEEEHHHHHHHCCCCCCCCCEEEECCCCEEEEEEEECC
PMPGGSVDNCITFQPVQNHVVIGDDSTIDFSKYYHFIPMPDLRAFANAGFPFSRMADLSQ
CCCCCCCCCEEEEEECCCEEEECCCCCEEHHHEEEECCCCHHHHHHCCCCCHHHHHHCCC
TITVMPKAPNEAQMETLLNTVGFIGAQTGFPAINLTVTDDGSTIQGKDADIMIVGGIPDK
EEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEECCCCCCEEEECCCCHH
LKDDKQIDLLVQATESWVKTPMRQTPFPGIVPDESDRAAETQSTLTSSGAMAAVIGFQSP
HCCCCCEEEEEEHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCC
YNDQRSVIALLADSPRGYEMLNDAVNDSGKRATMFGSVAVIRESGINSLRVGDVYYVGHL
CCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEEEEEEECCCCCEEEECCEEEECCC
PWFERLWYALANHPILLAVLAAISVVLLAWVLWRLLRIISRRRLNPDNE
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AMGMSAFPSFMTQATPATQPLINAEPAVAAQTEQNPQVGQVMPGVQGADAPIVAQNGPS
CCCCHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHCCCCCCCCCCEEECCCCC
RDVKLTFAQIAPPPGSMVLRGINPNGSIEFGMRSDEVVTKAMLNLEYTPSPSLLPVQSQL
CCEEEEEEEECCCCCCEEEEECCCCCCEEECCCCHHHHHHHHHEEEECCCCCEEECCCCE
KVYLNDELMGVLPVTKEQLGKKTLAQMPINPLFITDFNRVRLEFVGHYQDVCENPASTTL
EEEECCCEEEEECCCHHHHCHHHHHHCCCCEEEEECCCEEEEEEHHHHHHHHCCCCCEEE
WLDVGRSSGLDLTYQTLNVKNDLSHFPVPFFDPRDNRTNTLPMVFAGAPDVGLQQASAIV
EEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHH
ASWFGSRSGWRGQNFPVLYNQLPDRNAIVFATNDKRPDFLRDHPAVKAPVIEMINHPQNP
HHHHCCCCCCCCCCCCCCEECCCCCCEEEEEECCCCCCHHHCCCCCHHHHHHHHCCCCCC
YVKLLVVFGRDDKDLLQAAKGIAQGNILFRGESVVVNEVKPLLPRKPYDAPNWVRTDRPV
EEEEEEEECCCCHHHHHHHHCCCCCCEEEECCEEEEECHHHHCCCCCCCCCCCCCCCCCC
TFGELKTYEEQLQSSGLEPAAINVSLNLPPDLYLMRSTGIDMDINYRYTMPPVKDSSRMD
CHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCCEEEEEEEECCCCCCCCEEE
ISLNNQFLQSFNLSSKQEANRLLLRIPVLQGLLDGKTDVSIPALKLGATNQLRFDFEYMN
EEECHHHHHHCCCCCHHHHCCEEEEEHHHHHHHCCCCCCCCCEEEECCCCEEEEEEEECC
PMPGGSVDNCITFQPVQNHVVIGDDSTIDFSKYYHFIPMPDLRAFANAGFPFSRMADLSQ
CCCCCCCCCEEEEEECCCEEEECCCCCEEHHHEEEECCCCHHHHHHCCCCCHHHHHHCCC
TITVMPKAPNEAQMETLLNTVGFIGAQTGFPAINLTVTDDGSTIQGKDADIMIVGGIPDK
EEEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEECCCCCCEEEECCCCHH
LKDDKQIDLLVQATESWVKTPMRQTPFPGIVPDESDRAAETQSTLTSSGAMAAVIGFQSP
HCCCCCEEEEEEHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCC
YNDQRSVIALLADSPRGYEMLNDAVNDSGKRATMFGSVAVIRESGINSLRVGDVYYVGHL
CCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEEEEEEEEECCCCCEEEECCEEEECCC
PWFERLWYALANHPILLAVLAAISVVLLAWVLWRLLRIISRRRLNPDNE
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]