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The map label for this gene is lpxD [H]

Identifier: 170077563

GI number: 170077563

Start: 972180

End: 973205

Strand: Reverse

Name: lpxD [H]

Synonym: SYNPCC7002_A0941

Alternate gene names: 170077563

Gene position: 973205-972180 (Counterclockwise)

Preceding gene: 170077568

Following gene: 170077558

Centisome position: 32.35

GC content: 54.0

Gene sequence:

>1026_bases
ATGAACGTTTCTGAATTAATTCAAGTTTTAAAGTCTGATCTCATTATCGATCATTCCCTCGGAAGTGACCCGGAGATTAC
GGGGGTCGCCGCCATTGATGCCGCAAAATCCCAGGAAATCAGCTACATCGAAGGGGGGAAATTTGCCGCAAGGGTCGATA
CAACGGCAGCTTCGGCGTTAATCTTGCCTGCGGATGAAGATTTGCAACAACGAGCCACAGATCGCGGCCTAGCTTGGCTG
AGTACCAAGGAACCGCGTTTATTGTTCGCGGCGGCAATCAAGGTCTTTTATCAACCCTTCCGTCCGGCACCGGGGATTCA
CCCCACCGCAGTAATTGATCCGTCGGTGCAGTTGGGCGAGGCTGTCTCGGTGGGTGCCCATGTGGTGCTTTATCCGGGGG
TAAAAATTGGCGATCGCACTTGCATTATGGCCAATGCGGTGATTTATCCCGATGTGGAAATTGGTGCGGATACCTTACTC
CATGCCAATTGCACGATCCACGAGCGGGCCAAGATTGGTAATCATTGTGTAATCCACAGCGGCGCGGTAATCGGGGCAGA
AGGATTCGGCTTTGTGCCCACGGCCCAGGGCTGGTTCAAGATGGAACAGTCGGGAATTGTTGTCCTCGAAGATGGCGTTG
AAATTGGCTGTAACAGTGCGGTGGATCGGCCCGCCGTCGGGGAAACGCGCATTAAAACCCAAACCAAATTGGATAATCTC
GTCCATGTAGCCCATGGGGGAACCATTGGCTCGAACTGTGCCCTTGCCGCCCAGGTGGGTTTAGCAGGGGGCGTCACCGT
TGGGAATAATGTGCTCCTTGGGGGTCAGGTGGGCGTCGCGAACCAAGCAGTGATCGGTGATGGGGCGATCGCCACGGCCC
AAACCGGGATTAACAGTCGGGTTGCCCCTGGGGAAATTGTCTCTGGTAGTCCAGCGGTGCCCAATGCGGTTTACCGGAAA
GTTTCGGCCATCTACAAGCGTTTACCGGAAATGTACGAGGTGTTTCGTAAACTCAAAAAGGGTTAA

Upstream 100 bases:

>100_bases
TAAACCAATAAAAGCGGCGGTGAGGCTTGGTGCAGCTTTCTTGAGGGAAATGCCTTGGCCCTTGTTTAGATTAATCGTCA
TTTTCTATAGCTAAAATTCG

Downstream 100 bases:

>100_bases
ATCACCGCCAATTGGGGTGTTTGGATGGCGGGAATGCTGGCTTGGTTTTGTACTTGCTCAATGGCTTCATCCAGGAGGGC
TTGACCTTCGGCGACGGTGT

Product: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNVSELIQVLKSDLIIDHSLGSDPEITGVAAIDAAKSQEISYIEGGKFAARVDTTAASALILPADEDLQQRATDRGLAWL
STKEPRLLFAAAIKVFYQPFRPAPGIHPTAVIDPSVQLGEAVSVGAHVVLYPGVKIGDRTCIMANAVIYPDVEIGADTLL
HANCTIHERAKIGNHCVIHSGAVIGAEGFGFVPTAQGWFKMEQSGIVVLEDGVEIGCNSAVDRPAVGETRIKTQTKLDNL
VHVAHGGTIGSNCALAAQVGLAGGVTVGNNVLLGGQVGVANQAVIGDGAIATAQTGINSRVAPGEIVSGSPAVPNAVYRK
VSAIYKRLPEMYEVFRKLKKG

Sequences:

>Translated_341_residues
MNVSELIQVLKSDLIIDHSLGSDPEITGVAAIDAAKSQEISYIEGGKFAARVDTTAASALILPADEDLQQRATDRGLAWL
STKEPRLLFAAAIKVFYQPFRPAPGIHPTAVIDPSVQLGEAVSVGAHVVLYPGVKIGDRTCIMANAVIYPDVEIGADTLL
HANCTIHERAKIGNHCVIHSGAVIGAEGFGFVPTAQGWFKMEQSGIVVLEDGVEIGCNSAVDRPAVGETRIKTQTKLDNL
VHVAHGGTIGSNCALAAQVGLAGGVTVGNNVLLGGQVGVANQAVIGDGAIATAQTGINSRVAPGEIVSGSPAVPNAVYRK
VSAIYKRLPEMYEVFRKLKKG
>Mature_341_residues
MNVSELIQVLKSDLIIDHSLGSDPEITGVAAIDAAKSQEISYIEGGKFAARVDTTAASALILPADEDLQQRATDRGLAWL
STKEPRLLFAAAIKVFYQPFRPAPGIHPTAVIDPSVQLGEAVSVGAHVVLYPGVKIGDRTCIMANAVIYPDVEIGADTLL
HANCTIHERAKIGNHCVIHSGAVIGAEGFGFVPTAQGWFKMEQSGIVVLEDGVEIGCNSAVDRPAVGETRIKTQTKLDNL
VHVAHGGTIGSNCALAAQVGLAGGVTVGNNVLLGGQVGVANQAVIGDGAIATAQTGINSRVAPGEIVSGSPAVPNAVYRK
VSAIYKRLPEMYEVFRKLKKG

Specific function: Lipid A biosynthesis; third step. [C]

COG id: COG1044

COG function: function code M; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786376, Length=341, Percent_Identity=32.8445747800587, Blast_Score=176, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR011004
- InterPro:   IPR007691
- InterPro:   IPR020573 [H]

Pfam domain/function: PF00132 Hexapep; PF04613 LpxD [H]

EC number: 2.3.1.-

Molecular weight: Translated: 35569; Mature: 35569

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSELIQVLKSDLIIDHSLGSDPEITGVAAIDAAKSQEISYIEGGKFAARVDTTAASAL
CCHHHHHHHHHHHEEEECCCCCCCCEEEEEEECCCCCCCCEEECCCCEEEEEECCCCCEE
ILPADEDLQQRATDRGLAWLSTKEPRLLFAAAIKVFYQPFRPAPGIHPTAVIDPSVQLGE
EECCCHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHCC
AVSVGAHVVLYPGVKIGDRTCIMANAVIYPDVEIGADTLLHANCTIHERAKIGNHCVIHS
CCCCCEEEEEECCEEECCCEEEEECEEEECCCCCCCCEEEECCCEEEHHHCCCCEEEEEC
GAVIGAEGFGFVPTAQGWFKMEQSGIVVLEDGVEIGCNSAVDRPAVGETRIKTQTKLDNL
CEEECCCCCCCCCCCCCCEEECCCCEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHE
VHVAHGGTIGSNCALAAQVGLAGGVTVGNNVLLGGQVGVANQAVIGDGAIATAQTGINSR
EEEECCCCCCCCCEEEEEECCCCCEEECCCEEECCCCCCCCCEEECCCCEEEECCCCCCC
VAPGEIVSGSPAVPNAVYRKVSAIYKRLPEMYEVFRKLKKG
CCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure
MNVSELIQVLKSDLIIDHSLGSDPEITGVAAIDAAKSQEISYIEGGKFAARVDTTAASAL
CCHHHHHHHHHHHEEEECCCCCCCCEEEEEEECCCCCCCCEEECCCCEEEEEECCCCCEE
ILPADEDLQQRATDRGLAWLSTKEPRLLFAAAIKVFYQPFRPAPGIHPTAVIDPSVQLGE
EECCCHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHCC
AVSVGAHVVLYPGVKIGDRTCIMANAVIYPDVEIGADTLLHANCTIHERAKIGNHCVIHS
CCCCCEEEEEECCEEECCCEEEEECEEEECCCCCCCCEEEECCCEEEHHHCCCCEEEEEC
GAVIGAEGFGFVPTAQGWFKMEQSGIVVLEDGVEIGCNSAVDRPAVGETRIKTQTKLDNL
CEEECCCCCCCCCCCCCCEEECCCCEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHE
VHVAHGGTIGSNCALAAQVGLAGGVTVGNNVLLGGQVGVANQAVIGDGAIATAQTGINSR
EEEECCCCCCCCCEEEEEECCCCCEEECCCEEECCCCCCCCCEEECCCCEEEECCCCCCC
VAPGEIVSGSPAVPNAVYRKVSAIYKRLPEMYEVFRKLKKG
CCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA