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The map label for this gene is rpfC [H]

Identifier: 170077312

GI number: 170077312

Start: 716577

End: 718901

Strand: Reverse

Name: rpfC [H]

Synonym: SYNPCC7002_A0689

Alternate gene names: 170077312

Gene position: 718901-716577 (Counterclockwise)

Preceding gene: 170077313

Following gene: 170077311

Centisome position: 23.9

GC content: 49.89

Gene sequence:

>2325_bases
TTGTCCCGTGGTTTCAGCGTGCGGCCTGAAATTTTGATCTACATCTGCTCTTTGGAGAGGAGCGGTCTGATTTTTCTTCC
CATTATCTCCTGCCCTGAGGTTTGCAATTTTGTCATGATTTTAGTCGGTGAGCACCAAGCCCATTTCCTTGAATTTTTCC
TGGAGACCCTCCGGGGTATTGCCGCAGTGCAGGTTGCCCCCAGCGCCGCCCATCTGTCGGCTTTGGCGATCGCCAATCAT
CCAGAACTGATCATTGTGAACCTCGATTTTGTGTCCCGTCCGGAGCGCAAACTGTTTGCCCAGCTTAAAAGTGATCTGCA
CAGCCGCGATATCCCCCTGATTATTACCACCACGGATATCCATGCCCAAACCCGGGCCGAGGCTTTCTCGTTTGGGGCCG
ATGATGTGTTGCTATTGCCCTGCACCAGCACCGAATTACAAAAACGTGTCCAACAACAACTTAACCACAAACATCTCCAA
GCCCTGTGGTCAAACCAAACCGAGCAACTGCAACGGACAATCACCCGCCAAAGAATTCTCCGCGTCGTGATCAATCGGAT
TCGTCGTACCCTCAACCTCAACGAAATTTTTCAGAGCACGACTAAAGAAATCCATGATGCCCTGCACTGTGACCGGGTGG
TGATCTACAAGTTTAACCCCGACTGGAGTGGTCACTTTGTAGCTGAGGCCATGTCTCCCCAATGGCGATCGCTGATGAAT
GACGCCAGTGCGCGACAGCGTGAACTCCTAAAATATTCCGCAGTGCGTGATGACCGTTGTATTGTCAAAGTTTTTGAAAG
TGAGCTACCGGGCTGGGTAGAAGATACCTATCTCCAGGAAACCCAGGGGGGGATTTATCGTCAAGGCAATACCTACCGGG
CAGTCCATGATATTTACAAAGCCGGGTTTCCTCCCTGTTACATCGAGCTCCTCGAAAACTTCCAAGCCAAAGCCTATATC
ACCCTACCGATTTTTCTAGGCGATCGCCTTTGGGGACTCCTCGGCATCTACCAAAACAACGCCCCCCGCACCTGGCTTAC
CGAGGAAATTGAAATGCTGCGGCAGATCGCCACCCAACTGGGTGTGGCCCTCCAACAGGCCAAACTCCTAGAAACCCTAC
AGGCAGCCAAGGAAGAGGCAGAAAAGGCAAACCAAGCAAAAAGTCAATTTTTGGCCAATATGAGCCATGAACTCCGCACA
CCCCTCAGCGCCATTTTGGGGTTTACGGAGCTACTCACGGGGGATACTAACCTCACTTCTGATCAACTCGAATCCCTCGA
CATCATTACCCAGAGTGCCCAGCACCTGCTGAACCTGATCAACGATATTCTCTCCCTCTCAAAAATTGAGGCCGGGGAGA
CCAGCGTCCTTCGAGAAGCCTTTAATCTCGTTGAAGCTCTCAATGTTATCTACGATTTTGTTGTCCTTGCGGCGAAACAA
AAGCAACTAGAACTGATCTTTGAGCGTGATGCCAATGTACCGGAGGTGATTTACCTCGATGAAAAAAAGCTCAAGCAAGT
CTTAATTAATCTCTTGAGTAATGCCATTAAATTTACTGAGGTGGGTCGCGTTACCCTCAAAATTACCTATGATGCCCACC
AACAGAACTTACACTTTGCGGTAATTGATACGGGGCCTGGCATCCCAGAACATGAGCAGAACAAATTATTTCAGGTTTTT
CAGCAAACCAGCACAGGAATCCGTTCGCGCCAAGGTACGGGCCTGGGCCTCGCCATCAGTCAGCAGTTGGTACAGCTCAT
GGGGGGAGAGATCCGGGTAACAACGGCAGAAAATCAGGGTAGTTGCTTTTGGTTTGAGCTGTCCCTCGCCTCGCCAGAAA
AAGATCAAGCAGACATTTCAATTCAGGCTTTTGTAGAACACACGGGGCGATCGCCCAAAATTTTGCTCCTCAAGGATCAA
GTCGAGCAGCGGGAATTACTCTGTCAGCGACTGGCCAGGGCTGGTATCGAAACCCAGGCGATCGCCATGGAAGCAATCTC
CAATCACCCATGGCAACAATGGACACCAGACCTAATTTTGGTTGACCTGAAACTGGCCTCCGTCAATGGTGCGGAGATCT
TGAGCAATATCCAACAACAGCTCCAAACAGTCCCCCTAACCGAAGACCCAAAACTCATCGTGATTACCGCTGATATCTTT
CAAAATCAGCAAGATGAGCATTCGCGGTTAGCTTGTGATGACATTATTTATCACCCGGTCTCTTTGGAGGAACTTCTAGG
TAAGGTTGCCCATCATTTAGAGCAACATAGGGGAATCTTGAATCCCGTTGATGCCCACCCAAAATCACAAACCTCCCCGT
CCTAA

Upstream 100 bases:

>100_bases
CATTATTGCCGCCCAGATCCCCCCGTGCCAACCCACTGGAAGAGACAACCCCAGCCCTTAATCTAGATTATTTTTTCTGG
CTGAGCTACCGGGGAACTTT

Downstream 100 bases:

>100_bases
ATCCAGTTCGTTATGCTGAAGTTACCAGCGATTACCTTGTTTTAATCCCCTTGGCCTAAAGGCTACTAATCTTTAAATTT
TGTCACCGCCGATGGCTTCT

Product: two-component hybrid sensor and regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 774; Mature: 773

Protein sequence:

>774_residues
MSRGFSVRPEILIYICSLERSGLIFLPIISCPEVCNFVMILVGEHQAHFLEFFLETLRGIAAVQVAPSAAHLSALAIANH
PELIIVNLDFVSRPERKLFAQLKSDLHSRDIPLIITTTDIHAQTRAEAFSFGADDVLLLPCTSTELQKRVQQQLNHKHLQ
ALWSNQTEQLQRTITRQRILRVVINRIRRTLNLNEIFQSTTKEIHDALHCDRVVIYKFNPDWSGHFVAEAMSPQWRSLMN
DASARQRELLKYSAVRDDRCIVKVFESELPGWVEDTYLQETQGGIYRQGNTYRAVHDIYKAGFPPCYIELLENFQAKAYI
TLPIFLGDRLWGLLGIYQNNAPRTWLTEEIEMLRQIATQLGVALQQAKLLETLQAAKEEAEKANQAKSQFLANMSHELRT
PLSAILGFTELLTGDTNLTSDQLESLDIITQSAQHLLNLINDILSLSKIEAGETSVLREAFNLVEALNVIYDFVVLAAKQ
KQLELIFERDANVPEVIYLDEKKLKQVLINLLSNAIKFTEVGRVTLKITYDAHQQNLHFAVIDTGPGIPEHEQNKLFQVF
QQTSTGIRSRQGTGLGLAISQQLVQLMGGEIRVTTAENQGSCFWFELSLASPEKDQADISIQAFVEHTGRSPKILLLKDQ
VEQRELLCQRLARAGIETQAIAMEAISNHPWQQWTPDLILVDLKLASVNGAEILSNIQQQLQTVPLTEDPKLIVITADIF
QNQQDEHSRLACDDIIYHPVSLEELLGKVAHHLEQHRGILNPVDAHPKSQTSPS

Sequences:

>Translated_774_residues
MSRGFSVRPEILIYICSLERSGLIFLPIISCPEVCNFVMILVGEHQAHFLEFFLETLRGIAAVQVAPSAAHLSALAIANH
PELIIVNLDFVSRPERKLFAQLKSDLHSRDIPLIITTTDIHAQTRAEAFSFGADDVLLLPCTSTELQKRVQQQLNHKHLQ
ALWSNQTEQLQRTITRQRILRVVINRIRRTLNLNEIFQSTTKEIHDALHCDRVVIYKFNPDWSGHFVAEAMSPQWRSLMN
DASARQRELLKYSAVRDDRCIVKVFESELPGWVEDTYLQETQGGIYRQGNTYRAVHDIYKAGFPPCYIELLENFQAKAYI
TLPIFLGDRLWGLLGIYQNNAPRTWLTEEIEMLRQIATQLGVALQQAKLLETLQAAKEEAEKANQAKSQFLANMSHELRT
PLSAILGFTELLTGDTNLTSDQLESLDIITQSAQHLLNLINDILSLSKIEAGETSVLREAFNLVEALNVIYDFVVLAAKQ
KQLELIFERDANVPEVIYLDEKKLKQVLINLLSNAIKFTEVGRVTLKITYDAHQQNLHFAVIDTGPGIPEHEQNKLFQVF
QQTSTGIRSRQGTGLGLAISQQLVQLMGGEIRVTTAENQGSCFWFELSLASPEKDQADISIQAFVEHTGRSPKILLLKDQ
VEQRELLCQRLARAGIETQAIAMEAISNHPWQQWTPDLILVDLKLASVNGAEILSNIQQQLQTVPLTEDPKLIVITADIF
QNQQDEHSRLACDDIIYHPVSLEELLGKVAHHLEQHRGILNPVDAHPKSQTSPS
>Mature_773_residues
SRGFSVRPEILIYICSLERSGLIFLPIISCPEVCNFVMILVGEHQAHFLEFFLETLRGIAAVQVAPSAAHLSALAIANHP
ELIIVNLDFVSRPERKLFAQLKSDLHSRDIPLIITTTDIHAQTRAEAFSFGADDVLLLPCTSTELQKRVQQQLNHKHLQA
LWSNQTEQLQRTITRQRILRVVINRIRRTLNLNEIFQSTTKEIHDALHCDRVVIYKFNPDWSGHFVAEAMSPQWRSLMND
ASARQRELLKYSAVRDDRCIVKVFESELPGWVEDTYLQETQGGIYRQGNTYRAVHDIYKAGFPPCYIELLENFQAKAYIT
LPIFLGDRLWGLLGIYQNNAPRTWLTEEIEMLRQIATQLGVALQQAKLLETLQAAKEEAEKANQAKSQFLANMSHELRTP
LSAILGFTELLTGDTNLTSDQLESLDIITQSAQHLLNLINDILSLSKIEAGETSVLREAFNLVEALNVIYDFVVLAAKQK
QLELIFERDANVPEVIYLDEKKLKQVLINLLSNAIKFTEVGRVTLKITYDAHQQNLHFAVIDTGPGIPEHEQNKLFQVFQ
QTSTGIRSRQGTGLGLAISQQLVQLMGGEIRVTTAENQGSCFWFELSLASPEKDQADISIQAFVEHTGRSPKILLLKDQV
EQRELLCQRLARAGIETQAIAMEAISNHPWQQWTPDLILVDLKLASVNGAEILSNIQQQLQTVPLTEDPKLIVITADIFQ
NQQDEHSRLACDDIIYHPVSLEELLGKVAHHLEQHRGILNPVDAHPKSQTSPS

Specific function: Involved in the positive regulation of synthesis of extracellular enzymes and polysaccharide, and hence in pathogenicity. Can restore function to the non-pathogenic mutant 8237 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=241, Percent_Identity=42.7385892116183, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI48994928, Length=373, Percent_Identity=32.4396782841823, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI87081816, Length=386, Percent_Identity=33.6787564766839, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1788713, Length=406, Percent_Identity=29.5566502463054, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=39.9209486166008, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI1786912, Length=296, Percent_Identity=30.4054054054054, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=30.9417040358744, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=31.4159292035398, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=28.0487804878049, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790436, Length=251, Percent_Identity=26.6932270916335, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788549, Length=261, Percent_Identity=28.3524904214559, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1790861, Length=324, Percent_Identity=25.3086419753086, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1790346, Length=216, Percent_Identity=26.3888888888889, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786783, Length=286, Percent_Identity=24.1258741258741, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790300, Length=252, Percent_Identity=27.3809523809524, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788279, Length=203, Percent_Identity=26.1083743842365, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788545, Length=266, Percent_Identity=24.812030075188, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87460; Mature: 87329

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS50046 PHYTOCHROME_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRGFSVRPEILIYICSLERSGLIFLPIISCPEVCNFVMILVGEHQAHFLEFFLETLRGI
CCCCCCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHHHEECCCHHHHHHHHHHHHHCC
AAVQVAPSAAHLSALAIANHPELIIVNLDFVSRPERKLFAQLKSDLHSRDIPLIITTTDI
EEEEECCCHHHHHHHEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCC
HAQTRAEAFSFGADDVLLLPCTSTELQKRVQQQLNHKHLQALWSNQTEQLQRTITRQRIL
CHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RVVINRIRRTLNLNEIFQSTTKEIHDALHCDRVVIYKFNPDWSGHFVAEAMSPQWRSLMN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHCCHHHHHHHH
DASARQRELLKYSAVRDDRCIVKVFESELPGWVEDTYLQETQGGIYRQGNTYRAVHDIYK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEECCCCHHHHHHHHH
AGFPPCYIELLENFQAKAYITLPIFLGDRLWGLLGIYQNNAPRTWLTEEIEMLRQIATQL
CCCCHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
GVALQQAKLLETLQAAKEEAEKANQAKSQFLANMSHELRTPLSAILGFTELLTGDTNLTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DQLESLDIITQSAQHLLNLINDILSLSKIEAGETSVLREAFNLVEALNVIYDFVVLAAKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQLELIFERDANVPEVIYLDEKKLKQVLINLLSNAIKFTEVGRVTLKITYDAHQQNLHFA
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHEECCEEEEEEEECCCCCCEEEE
VIDTGPGIPEHEQNKLFQVFQQTSTGIRSRQGTGLGLAISQQLVQLMGGEIRVTTAENQG
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCC
SCFWFELSLASPEKDQADISIQAFVEHTGRSPKILLLKDQVEQRELLCQRLARAGIETQA
CEEEEEEEECCCCCCCCCEEHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHH
IAMEAISNHPWQQWTPDLILVDLKLASVNGAEILSNIQQQLQTVPLTEDPKLIVITADIF
HHHHHHCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHH
QNQQDEHSRLACDDIIYHPVSLEELLGKVAHHLEQHRGILNPVDAHPKSQTSPS
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRGFSVRPEILIYICSLERSGLIFLPIISCPEVCNFVMILVGEHQAHFLEFFLETLRGI
CCCCCCCCEEEEEEEECCCCCEEEEECCCCHHHHHHHHHEECCCHHHHHHHHHHHHHCC
AAVQVAPSAAHLSALAIANHPELIIVNLDFVSRPERKLFAQLKSDLHSRDIPLIITTTDI
EEEEECCCHHHHHHHEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCC
HAQTRAEAFSFGADDVLLLPCTSTELQKRVQQQLNHKHLQALWSNQTEQLQRTITRQRIL
CHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RVVINRIRRTLNLNEIFQSTTKEIHDALHCDRVVIYKFNPDWSGHFVAEAMSPQWRSLMN
HHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHCCHHHHHHHH
DASARQRELLKYSAVRDDRCIVKVFESELPGWVEDTYLQETQGGIYRQGNTYRAVHDIYK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEECCCCHHHHHHHHH
AGFPPCYIELLENFQAKAYITLPIFLGDRLWGLLGIYQNNAPRTWLTEEIEMLRQIATQL
CCCCHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
GVALQQAKLLETLQAAKEEAEKANQAKSQFLANMSHELRTPLSAILGFTELLTGDTNLTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DQLESLDIITQSAQHLLNLINDILSLSKIEAGETSVLREAFNLVEALNVIYDFVVLAAKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQLELIFERDANVPEVIYLDEKKLKQVLINLLSNAIKFTEVGRVTLKITYDAHQQNLHFA
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHEECCEEEEEEEECCCCCCEEEE
VIDTGPGIPEHEQNKLFQVFQQTSTGIRSRQGTGLGLAISQQLVQLMGGEIRVTTAENQG
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCC
SCFWFELSLASPEKDQADISIQAFVEHTGRSPKILLLKDQVEQRELLCQRLARAGIETQA
CEEEEEEEECCCCCCCCCEEHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHH
IAMEAISNHPWQQWTPDLILVDLKLASVNGAEILSNIQQQLQTVPLTEDPKLIVITADIF
HHHHHHCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHH
QNQQDEHSRLACDDIIYHPVSLEELLGKVAHHLEQHRGILNPVDAHPKSQTSPS
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1645442 [H]