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The map label for this gene is glnP [H]

Identifier: 170026443

GI number: 170026443

Start: 4678179

End: 4678934

Strand: Direct

Name: glnP [H]

Synonym: YPK_4239

Alternate gene names: 170026443

Gene position: 4678179-4678934 (Clockwise)

Preceding gene: 170026442

Following gene: 170026445

Centisome position: 99.76

GC content: 49.47

Gene sequence:

>756_bases
ATGGATTTTACCATTATCGTTGATAACTGGCGTTATCTGCTGTGGGGGACTTTCCCTGATGGCCCTCTGGGAGGGGCGGC
ATTGACCGTGGTGATCAGTATCATGGCTGGGGTAACCTCAGCCGTATTAGGCACTGTGTTGGGCGTGGCATTGGCGATGT
CCCGTGGTGTCTGGGCGGGAATATTGGCCGCTGTTTTGGGCTTCTTCCGTGCGATTCCGGTGATTATGTTGATTTTTTGG
ACGTATTTCCTGCTACCGATCGTTTTTGGTGTGGATATACCTGAAATCACCACTGTGGTGTGTGCACTGGCGCTGATTGC
TTCTGCTTATCTGGCTCATGCGGTAAAGGCCGGGATAATGGCTATTGGTGCCGGGCAGTGGCAAGCGGGGCTGTCGTTAG
GTTTTAATCGCTGGCAGACCCTGTGGTTTATTGTATTGCCACAAGCGCTGCGCATGATGGTGCCGTCCTTTATTAATCAA
TGGATATCATTGATTAAAGATACATCGCTGGCTTATATCGTCGGAGTGAATGAGCTGACCTTTTTGGCTACACAGGTTAA
TAACCGCAGTATGGTTTACCCGATGGAAGTCTTTCTGTTTGTGGCATTGGTCTATTTTGTTTTATGTCTGGCGCTGGATC
TACTGGCTAACGGCCTTAATCGCCGCTTTAGCCCACAGCATGCCATTAAAAAACAAAGCGCCATGGCACGTTCATGGCGC
TGGTGGTGTAACAAGCTAACACTGCAATCGAGTTAA

Upstream 100 bases:

>100_bases
GCATTCGGGGTTGCAACCCTATTGTATATTTTCATCATCGCGCTAATTGAGGCTTGGGGTATGTGGCGTCAACAGCGAAC
CGTCGTCCGAGGGCACTGAG

Downstream 100 bases:

>100_bases
TTGATTACAGGCAGGCTAATTCATTACAGGTAAATTAATCGCGGGTGATATGCCAGCCTCTTTCCTTCCACAAATCAGGC
AGTTGCTGAATATCCGTGAA

Product: polar amino acid ABC transporter inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MDFTIIVDNWRYLLWGTFPDGPLGGAALTVVISIMAGVTSAVLGTVLGVALAMSRGVWAGILAAVLGFFRAIPVIMLIFW
TYFLLPIVFGVDIPEITTVVCALALIASAYLAHAVKAGIMAIGAGQWQAGLSLGFNRWQTLWFIVLPQALRMMVPSFINQ
WISLIKDTSLAYIVGVNELTFLATQVNNRSMVYPMEVFLFVALVYFVLCLALDLLANGLNRRFSPQHAIKKQSAMARSWR
WWCNKLTLQSS

Sequences:

>Translated_251_residues
MDFTIIVDNWRYLLWGTFPDGPLGGAALTVVISIMAGVTSAVLGTVLGVALAMSRGVWAGILAAVLGFFRAIPVIMLIFW
TYFLLPIVFGVDIPEITTVVCALALIASAYLAHAVKAGIMAIGAGQWQAGLSLGFNRWQTLWFIVLPQALRMMVPSFINQ
WISLIKDTSLAYIVGVNELTFLATQVNNRSMVYPMEVFLFVALVYFVLCLALDLLANGLNRRFSPQHAIKKQSAMARSWR
WWCNKLTLQSS
>Mature_251_residues
MDFTIIVDNWRYLLWGTFPDGPLGGAALTVVISIMAGVTSAVLGTVLGVALAMSRGVWAGILAAVLGFFRAIPVIMLIFW
TYFLLPIVFGVDIPEITTVVCALALIASAYLAHAVKAGIMAIGAGQWQAGLSLGFNRWQTLWFIVLPQALRMMVPSFINQ
WISLIKDTSLAYIVGVNELTFLATQVNNRSMVYPMEVFLFVALVYFVLCLALDLLANGLNRRFSPQHAIKKQSAMARSWR
WWCNKLTLQSS

Specific function: Part of the ABC transporter complex glnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=214, Percent_Identity=35.5140186915888, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788226, Length=214, Percent_Identity=34.1121495327103, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=31.8627450980392, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI87082239, Length=209, Percent_Identity=30.622009569378, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787087, Length=222, Percent_Identity=25.6756756756757, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48994930, Length=136, Percent_Identity=33.8235294117647, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788646, Length=227, Percent_Identity=25.5506607929515, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786874, Length=232, Percent_Identity=23.2758620689655, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788645, Length=228, Percent_Identity=26.3157894736842, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27694; Mature: 27694

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTIIVDNWRYLLWGTFPDGPLGGAALTVVISIMAGVTSAVLGTVLGVALAMSRGVWAG
CCEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ILAAVLGFFRAIPVIMLIFWTYFLLPIVFGVDIPEITTVVCALALIASAYLAHAVKAGIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGAGQWQAGLSLGFNRWQTLWFIVLPQALRMMVPSFINQWISLIKDTSLAYIVGVNELT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHH
FLATQVNNRSMVYPMEVFLFVALVYFVLCLALDLLANGLNRRFSPQHAIKKQSAMARSWR
HHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
WWCNKLTLQSS
HHHHHHCCCCC
>Mature Secondary Structure
MDFTIIVDNWRYLLWGTFPDGPLGGAALTVVISIMAGVTSAVLGTVLGVALAMSRGVWAG
CCEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ILAAVLGFFRAIPVIMLIFWTYFLLPIVFGVDIPEITTVVCALALIASAYLAHAVKAGIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGAGQWQAGLSLGFNRWQTLWFIVLPQALRMMVPSFINQWISLIKDTSLAYIVGVNELT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHH
FLATQVNNRSMVYPMEVFLFVALVYFVLCLALDLLANGLNRRFSPQHAIKKQSAMARSWR
HHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
WWCNKLTLQSS
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 9384377 [H]