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The map label for this gene is argB

Identifier: 170026295

GI number: 170026295

Start: 4516161

End: 4516937

Strand: Reverse

Name: argB

Synonym: YPK_4088

Alternate gene names: 170026295

Gene position: 4516937-4516161 (Counterclockwise)

Preceding gene: 170026296

Following gene: 170026294

Centisome position: 96.32

GC content: 51.09

Gene sequence:

>777_bases
ATGATGAACCCGTTGGTCATTAAATTAGGTGGCGTATTGCTGGACAGCGAAGAAGCACTGGAACGCCTGTTTACTGCATT
GGTGACCTATCGTGAGAAACATGAGCGCCCGCTTGTGATTATGCACGGTGGTGGCTGTCTGGTGGACGAATTGATGAAAA
GACTCGCCTTGCCAGTAGTGAAGAAGAACGGCCTGCGCGTCACCCCCGCTGATCAGATTGATATCATTACTGGCGCACTG
GCGGGTACCGCGAATAAAACGCTCTTGGCTTGGGCGGTGAAACATCAGATCAATGCTGTTGGCTTGTGCCTGGCTGATGG
TAATACTGTGACGGTTACTCTGCTGGATGCTGAATTGGGCCACGTGGGTAAAGCGCAACCGGGTTCTGCGGCACTGGTAC
AAACTTTGTTGGCGGCAGGTTATATGCCAATCATCAGCTCAATTGGTATTACTGTTGAAGGGCAATTGATGAATGTAAAT
GCCGATCAAGCGGCAACCGCATTAGCAGCAACGCTCGGTGCTGATTTAATCTTATTGTCCGATGTCAGTGGCATTCTCGA
TGGTAAAGGGCAGCGGATTGCTGAAATGACGGCGCAAAAAGCAGAGCAATTAATCGCTCAGGGCATCATCACCGATGGTA
TGGTCGTCAAAGTGAATGCGGCACTGGATGCCGCGCGTTCATTAGGTCGCCCGGTTGATATCGCCAGTTGGCGTCATTCT
GAGCAACTCCCCGCACTGTTCAACGGTGTACCGATTGGTACGCGTATTTCGGTCTAA

Upstream 100 bases:

>100_bases
GCAGTAAACAGATTGTGAGCCATAAATTGTGAGCAACAGAACCGGCAGATACGCATATTTTATCTGATTATATTTTATCC
GATTATATTGAGGCAAAAGC

Downstream 100 bases:

>100_bases
TATTATTGACGATGACTATAAAGTTATACCCAAAGTCATTGGCGTTACAGGTAGGCAGCCAGCAAACTCATCCGTAAGTA
AGTGATTCGGGTGAGTGGGC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MMNPLVIKLGGVLLDSEEALERLFTALVTYREKHERPLVIMHGGGCLVDELMKRLALPVVKKNGLRVTPADQIDIITGAL
AGTANKTLLAWAVKHQINAVGLCLADGNTVTVTLLDAELGHVGKAQPGSAALVQTLLAAGYMPIISSIGITVEGQLMNVN
ADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWRHS
EQLPALFNGVPIGTRISV

Sequences:

>Translated_258_residues
MMNPLVIKLGGVLLDSEEALERLFTALVTYREKHERPLVIMHGGGCLVDELMKRLALPVVKKNGLRVTPADQIDIITGAL
AGTANKTLLAWAVKHQINAVGLCLADGNTVTVTLLDAELGHVGKAQPGSAALVQTLLAAGYMPIISSIGITVEGQLMNVN
ADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWRHS
EQLPALFNGVPIGTRISV
>Mature_258_residues
MMNPLVIKLGGVLLDSEEALERLFTALVTYREKHERPLVIMHGGGCLVDELMKRLALPVVKKNGLRVTPADQIDIITGAL
AGTANKTLLAWAVKHQINAVGLCLADGNTVTVTLLDAELGHVGKAQPGSAALVQTLLAAGYMPIISSIGITVEGQLMNVN
ADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWRHS
EQLPALFNGVPIGTRISV

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=256, Percent_Identity=84.765625, Blast_Score=418, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_YERP3 (A7FD00)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001399128.1
- ProteinModelPortal:   A7FD00
- SMR:   A7FD00
- STRING:   A7FD00
- GeneID:   5385361
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_0128
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MVLCGST
- ProtClustDB:   PRK00942
- BioCyc:   YPSE349747:YPSIP31758_0128-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 26987; Mature: 26987

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: BINDING 66-66 BINDING 158-158

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNPLVIKLGGVLLDSEEALERLFTALVTYREKHERPLVIMHGGGCLVDELMKRLALPVV
CCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCC
KKNGLRVTPADQIDIITGALAGTANKTLLAWAVKHQINAVGLCLADGNTVTVTLLDAELG
CCCCCEECCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEEECCCEEEEEEEECCCC
HVGKAQPGSAALVQTLLAAGYMPIISSIGITVEGQLMNVNADQAATALAATLGADLILLS
CCCCCCCCHHHHHHHHHHCCHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEE
DVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWRHS
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCHHCCCCC
EQLPALFNGVPIGTRISV
CCCCHHHCCCCCCEEECC
>Mature Secondary Structure
MMNPLVIKLGGVLLDSEEALERLFTALVTYREKHERPLVIMHGGGCLVDELMKRLALPVV
CCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCC
KKNGLRVTPADQIDIITGALAGTANKTLLAWAVKHQINAVGLCLADGNTVTVTLLDAELG
CCCCCEECCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEEECCCEEEEEEEECCCC
HVGKAQPGSAALVQTLLAAGYMPIISSIGITVEGQLMNVNADQAATALAATLGADLILLS
CCCCCCCCHHHHHHHHHHCCHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHCCCEEEEE
DVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWRHS
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCHHCCCCC
EQLPALFNGVPIGTRISV
CCCCHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA