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The map label for this gene is argC [H]

Identifier: 170026296

GI number: 170026296

Start: 4517117

End: 4518121

Strand: Reverse

Name: argC [H]

Synonym: YPK_4089

Alternate gene names: 170026296

Gene position: 4518121-4517117 (Counterclockwise)

Preceding gene: 170026300

Following gene: 170026295

Centisome position: 96.35

GC content: 50.65

Gene sequence:

>1005_bases
ATGTTAAATACGTTGATTGTTGGTGCCAGTGGCTATGCCGGCGCGGAGCTTACGGCTTACCTTAATCGTCACCCACATAT
GAACATAACCGGTTTAGCGGTTTCAGCGCAAAGTGCAGATGCAGGAAAATTACTTTCCGAACTGCATCCGCAGTTAAAAG
GCATCCTTGATCTCCCGCTACAGCCCTTGGTAGATGTGGCTCAGGCGGCTAAAGGTATCGATGTGGTTTTCCTCGCTACC
GCTCATGAGGTCAGCCATGATTTGGCACCACAATTTTTAGCCGCTGGCTGTGTGGTATTTGATCTTTCCGGTGCATTCCG
TGTGCGTGATGCGGCGTTTTACAGCCAATATTACGGTTTTGAACACCAACATCCCGATTGGCTCGATAAGGCGGTTTATG
GCCTGGCAGAATGGCAATCAGAAGACATTAAGCAAGCTCAATTGATTGCTGTTCCTGGTTGTTATCCAACCGCATCACAA
CTGGCGCTTAAACCGTTGGTTGATGGGCAATTACTGAACGATGCACAGTGGCCAGTCATTAATGCCGTCAGTGGTGTCAG
CGGTGCAGGGCGTAAAGCCAGCATGGGCAACAGCTTCTGTGAAGTTAGCTTGCAGCCATATGGCCTATTTACCCACCGTC
ACCAGCCAGAAATTGTTGCCCATCTTGGCACCCCCGTCATTTTTACACCGCATCTGGGGAATTTTGCCCGAGGGATCTTG
GCGACGATTACCTGCCGCCTGAAAGCTGGGGTCACGGCGCAAAACATCGCCGATGCCTATCACCATGCTTATCAGAATAA
GCCACTGGTGCGGTTGTATCAACAAGGTGTCCCGGCGCTGAAAGCCGTGGTCGGCCTACCTTTCTGTGATATTGGTTTCT
CGGTACAAGGCGAGCATTTAATTATTGTTGCCACCGAAGATAACCTGCTGAAAGGTGCTGCGGCTCAGGCCGTACAATGT
ATGAATATCCGTTTTGGCTTCCCGGAAACGCAGTCCCTGTTGTAG

Upstream 100 bases:

>100_bases
CCTTGCTGAGAACCCGAATACCAGTTTTGACTATTTATGTTTTTATATGCATAGGCTTTTATTGACATAAATAAAAATAC
TCAGAAGGTGAACTGAACCC

Downstream 100 bases:

>100_bases
CGTTCGGTTGCAAGCAATAGATTGTAAATGATTGATTGTAAGTGATTGATTGTAATTAATGGATTGCAAGAAATAGATTG
CAGTAAACAGATTGTGAGCC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLNTLIVGASGYAGAELTAYLNRHPHMNITGLAVSAQSADAGKLLSELHPQLKGILDLPLQPLVDVAQAAKGIDVVFLAT
AHEVSHDLAPQFLAAGCVVFDLSGAFRVRDAAFYSQYYGFEHQHPDWLDKAVYGLAEWQSEDIKQAQLIAVPGCYPTASQ
LALKPLVDGQLLNDAQWPVINAVSGVSGAGRKASMGNSFCEVSLQPYGLFTHRHQPEIVAHLGTPVIFTPHLGNFARGIL
ATITCRLKAGVTAQNIADAYHHAYQNKPLVRLYQQGVPALKAVVGLPFCDIGFSVQGEHLIIVATEDNLLKGAAAQAVQC
MNIRFGFPETQSLL

Sequences:

>Translated_334_residues
MLNTLIVGASGYAGAELTAYLNRHPHMNITGLAVSAQSADAGKLLSELHPQLKGILDLPLQPLVDVAQAAKGIDVVFLAT
AHEVSHDLAPQFLAAGCVVFDLSGAFRVRDAAFYSQYYGFEHQHPDWLDKAVYGLAEWQSEDIKQAQLIAVPGCYPTASQ
LALKPLVDGQLLNDAQWPVINAVSGVSGAGRKASMGNSFCEVSLQPYGLFTHRHQPEIVAHLGTPVIFTPHLGNFARGIL
ATITCRLKAGVTAQNIADAYHHAYQNKPLVRLYQQGVPALKAVVGLPFCDIGFSVQGEHLIIVATEDNLLKGAAAQAVQC
MNIRFGFPETQSLL
>Mature_334_residues
MLNTLIVGASGYAGAELTAYLNRHPHMNITGLAVSAQSADAGKLLSELHPQLKGILDLPLQPLVDVAQAAKGIDVVFLAT
AHEVSHDLAPQFLAAGCVVFDLSGAFRVRDAAFYSQYYGFEHQHPDWLDKAVYGLAEWQSEDIKQAQLIAVPGCYPTASQ
LALKPLVDGQLLNDAQWPVINAVSGVSGAGRKASMGNSFCEVSLQPYGLFTHRHQPEIVAHLGTPVIFTPHLGNFARGIL
ATITCRLKAGVTAQNIADAYHHAYQNKPLVRLYQQGVPALKAVVGLPFCDIGFSVQGEHLIIVATEDNLLKGAAAQAVQC
MNIRFGFPETQSLL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=334, Percent_Identity=77.5449101796407, Blast_Score=540, Evalue=1e-155,
Organism=Saccharomyces cerevisiae, GI6320913, Length=333, Percent_Identity=30.03003003003, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 35855; Mature: 35855

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS01224 ARGC ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTLIVGASGYAGAELTAYLNRHPHMNITGLAVSAQSADAGKLLSELHPQLKGILDLPL
CCCEEEEECCCCCCCHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHCHHHHHHHCCCC
QPLVDVAQAAKGIDVVFLATAHEVSHDLAPQFLAAGCVVFDLSGAFRVRDAAFYSQYYGF
HHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCEEEEECCCCEEHHHHHHHHHHCCC
EHQHPDWLDKAVYGLAEWQSEDIKQAQLIAVPGCYPTASQLALKPLVDGQLLNDAQWPVI
CCCCCHHHHHHHHHHHHHCHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCHH
NAVSGVSGAGRKASMGNSFCEVSLQPYGLFTHRHQPEIVAHLGTPVIFTPHLGNFARGIL
HHHCCCCCCCCCCCCCCCEEEEEECCEEEECCCCCCHHHHHCCCCEEECCCCCHHHHHHH
ATITCRLKAGVTAQNIADAYHHAYQNKPLVRLYQQGVPALKAVVGLPFCDIGFSVQGEHL
HHHEEHHCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCCEECCCCEECCCEE
IIVATEDNLLKGAAAQAVQCMNIRFGFPETQSLL
EEEECCCCHHHHHHHHHHHHEEEEECCCCHHHCC
>Mature Secondary Structure
MLNTLIVGASGYAGAELTAYLNRHPHMNITGLAVSAQSADAGKLLSELHPQLKGILDLPL
CCCEEEEECCCCCCCHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHCHHHHHHHCCCC
QPLVDVAQAAKGIDVVFLATAHEVSHDLAPQFLAAGCVVFDLSGAFRVRDAAFYSQYYGF
HHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHCCEEEEECCCCEEHHHHHHHHHHCCC
EHQHPDWLDKAVYGLAEWQSEDIKQAQLIAVPGCYPTASQLALKPLVDGQLLNDAQWPVI
CCCCCHHHHHHHHHHHHHCHHCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCHH
NAVSGVSGAGRKASMGNSFCEVSLQPYGLFTHRHQPEIVAHLGTPVIFTPHLGNFARGIL
HHHCCCCCCCCCCCCCCCEEEEEECCEEEECCCCCCHHHHHCCCCEEECCCCCHHHHHHH
ATITCRLKAGVTAQNIADAYHHAYQNKPLVRLYQQGVPALKAVVGLPFCDIGFSVQGEHL
HHHEEHHCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCCEECCCCEECCCEE
IIVATEDNLLKGAAAQAVQCMNIRFGFPETQSLL
EEEECCCCHHHHHHHHHHHHEEEEECCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]