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The map label for this gene is yscC [H]

Identifier: 170026130

GI number: 170026130

Start: 4313699

End: 4315216

Strand: Reverse

Name: yscC [H]

Synonym: YPK_3917

Alternate gene names: 170026130

Gene position: 4315216-4313699 (Counterclockwise)

Preceding gene: 170026133

Following gene: 170026129

Centisome position: 92.02

GC content: 43.87

Gene sequence:

>1518_bases
ATGTCGCTAATCTATATCATGAGAAAAATAACGGGTCTGATATTACTTTTTTTTGCCACATTGTTGCCTTATGGGAAATT
TTCTTATGGAAAAGCGATTCCTTGGCAAGGCGAGCCTTTTTTTATTTATAGCCGAGGCATGACAGTTTCTGAATTATTAA
AAGATTTGGGGATGAATTACGGTATTCCTGTGGTGATCAGTTCGGAAATAAACGAGCACTTTACTGGAAAGATTAGGGAT
AAGACACCTGAAAAAATCCTATCGGAGTTGGCTGGGCGATATAATATAACGTGGTATTACGATGGTGAAACACTCTATTT
TTACCCAGTTCAATCAATCAAGCGGGAGTTTATATCCCCCGATGGTCTGGCTGCCAATACGTTAGTTAAATATCTCCAGC
GCGGTGACGTGCTGGCGGGGAAAAACTGTGCCATAAAAGCGATCCCCCACCTTGATACCCTTGAGGTCAAGGGAGTGCCT
ATCTGCATCGAACGCGTAAAGTCAGTAAGCAAAATGCTTTCTGAGCAAGTTCGTCACCAAAACCAAAATAAAGAAACAGT
GAAAGTTTTCCCGCTGAAATATGCTTCAGCAGCGGATTCGGATTATCAGTACCGAGATCAAAACGTCAGATTACCGGGGT
TGGTCAGTGTGTTACGTGAGTTGAACCAAGGGAATAATTTGCCTTTGGCGGGCGGTAACCAACCAGATGGAAATCAAGCA
AGCTCACCGGTGTTTTCGGCTGATCCTCGGCAAAATGCCGTCATTATTCGCGATCGCCAGGCTAATATGCCGATTTATCG
CAGCTTGATTACCCAACTGGATCAGCGGCCAATTCAGATAGAAATTTCTGTCACTATTATTGATGTTGATGCGGGAGATA
TCAGCCAACTGGGTGTTGATTGGTCTGCATCTGCTTCTATTGGTGGAACGGGGGTCTCATTTAATAGCACCTTCGCCAAG
AATAATGCTGAAGGCTTTTCTACCGTGATTGGTGATACGGGGAACTTTATGGTTCGTCTGAATGCGTTACAAAAAAATTC
ACGAGCCAGAATTTTATCTCAACCTTCAGTGGTGACCCTGAACAATATTCAGGCGGTACTGGATAAAAACGTGACGTTTT
ATACCAAGCTGCAAGGTGAGAAAGTGGCCAAACTTGAATCTGTCACTTCAGGGTCATTACTGCGAGTGACGCCAAGAATG
ATCGAGACCGAAGGGGTACAAGAGGTTTTACTGAATCTCAATATTCAGGATGGTCAGCAGCAAGCTTCTACCAATAGTAA
TGAGCCATTACCCGAAATACGAAACTCAGATATTTCGACGCAGGCCACGCTACAGGTTGGACAAAGTTTACTCTTGGGCG
GATTTATTCAGGACACGCAGATTGAGTCACAAAATAAAATTCCTTTACTGGGCGATATTCCGCTATTAGGTGGGTTGTTC
CGTAGTACAGATAAACAATCTCACAGCGTGGTCAGACTCTTCCTGATCAAGGCCGTTCCGGTTAATGCAGGGGAATAA

Upstream 100 bases:

>100_bases
ACCTTATTGTGGCTTTCAGATTGTATAAGGATAATTATTCAATATATTGATAGTCGGTTTACGCCAAAAACCGTATTTAA
ATTTAAGAAATTATAAGTGG

Downstream 100 bases:

>100_bases
CATGACCACCGTATTCAAGCTTCGCCTGTTAAATGGTGATCTCAATGGTCGTGAGCTGATATTACCGGAAGGTGAATTTA
CACTGGGGGAGCAGGGGTGT

Product: YscC/HrcC family type III secretion outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MSLIYIMRKITGLILLFFATLLPYGKFSYGKAIPWQGEPFFIYSRGMTVSELLKDLGMNYGIPVVISSEINEHFTGKIRD
KTPEKILSELAGRYNITWYYDGETLYFYPVQSIKREFISPDGLAANTLVKYLQRGDVLAGKNCAIKAIPHLDTLEVKGVP
ICIERVKSVSKMLSEQVRHQNQNKETVKVFPLKYASAADSDYQYRDQNVRLPGLVSVLRELNQGNNLPLAGGNQPDGNQA
SSPVFSADPRQNAVIIRDRQANMPIYRSLITQLDQRPIQIEISVTIIDVDAGDISQLGVDWSASASIGGTGVSFNSTFAK
NNAEGFSTVIGDTGNFMVRLNALQKNSRARILSQPSVVTLNNIQAVLDKNVTFYTKLQGEKVAKLESVTSGSLLRVTPRM
IETEGVQEVLLNLNIQDGQQQASTNSNEPLPEIRNSDISTQATLQVGQSLLLGGFIQDTQIESQNKIPLLGDIPLLGGLF
RSTDKQSHSVVRLFLIKAVPVNAGE

Sequences:

>Translated_505_residues
MSLIYIMRKITGLILLFFATLLPYGKFSYGKAIPWQGEPFFIYSRGMTVSELLKDLGMNYGIPVVISSEINEHFTGKIRD
KTPEKILSELAGRYNITWYYDGETLYFYPVQSIKREFISPDGLAANTLVKYLQRGDVLAGKNCAIKAIPHLDTLEVKGVP
ICIERVKSVSKMLSEQVRHQNQNKETVKVFPLKYASAADSDYQYRDQNVRLPGLVSVLRELNQGNNLPLAGGNQPDGNQA
SSPVFSADPRQNAVIIRDRQANMPIYRSLITQLDQRPIQIEISVTIIDVDAGDISQLGVDWSASASIGGTGVSFNSTFAK
NNAEGFSTVIGDTGNFMVRLNALQKNSRARILSQPSVVTLNNIQAVLDKNVTFYTKLQGEKVAKLESVTSGSLLRVTPRM
IETEGVQEVLLNLNIQDGQQQASTNSNEPLPEIRNSDISTQATLQVGQSLLLGGFIQDTQIESQNKIPLLGDIPLLGGLF
RSTDKQSHSVVRLFLIKAVPVNAGE
>Mature_504_residues
SLIYIMRKITGLILLFFATLLPYGKFSYGKAIPWQGEPFFIYSRGMTVSELLKDLGMNYGIPVVISSEINEHFTGKIRDK
TPEKILSELAGRYNITWYYDGETLYFYPVQSIKREFISPDGLAANTLVKYLQRGDVLAGKNCAIKAIPHLDTLEVKGVPI
CIERVKSVSKMLSEQVRHQNQNKETVKVFPLKYASAADSDYQYRDQNVRLPGLVSVLRELNQGNNLPLAGGNQPDGNQAS
SPVFSADPRQNAVIIRDRQANMPIYRSLITQLDQRPIQIEISVTIIDVDAGDISQLGVDWSASASIGGTGVSFNSTFAKN
NAEGFSTVIGDTGNFMVRLNALQKNSRARILSQPSVVTLNNIQAVLDKNVTFYTKLQGEKVAKLESVTSGSLLRVTPRMI
ETEGVQEVLLNLNIQDGQQQASTNSNEPLPEIRNSDISTQATLQVGQSLLLGGFIQDTQIESQNKIPLLGDIPLLGGLFR
STDKQSHSVVRLFLIKAVPVNAGE

Specific function: Very likely required for the export process of the yop proteins [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI87082242, Length=410, Percent_Identity=27.3170731707317, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1789793, Length=252, Percent_Identity=25, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR003522 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 55700; Mature: 55569

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIYIMRKITGLILLFFATLLPYGKFSYGKAIPWQGEPFFIYSRGMTVSELLKDLGMNY
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCC
GIPVVISSEINEHFTGKIRDKTPEKILSELAGRYNITWYYDGETLYFYPVQSIKREFISP
CCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCEEEEEEHHHHHHHHCCC
DGLAANTLVKYLQRGDVLAGKNCAIKAIPHLDTLEVKGVPICIERVKSVSKMLSEQVRHQ
CCCHHHHHHHHHHCCCEEECCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHC
NQNKETVKVFPLKYASAADSDYQYRDQNVRLPGLVSVLRELNQGNNLPLAGGNQPDGNQA
CCCCCEEEEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SSPVFSADPRQNAVIIRDRQANMPIYRSLITQLDQRPIQIEISVTIIDVDAGDISQLGVD
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHCCCC
WSASASIGGTGVSFNSTFAKNNAEGFSTVIGDTGNFMVRLNALQKNSRARILSQPSVVTL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHEECCCCCEEEEEEECCCCCCCEEECCCCEEEE
NNIQAVLDKNVTFYTKLQGEKVAKLESVTSGSLLRVTPRMIETEGVQEVLLNLNIQDGQQ
CCHHHHHCCCCEEEEEECCCHHHHHHHCCCCCEEEECHHHHHHCCHHHHHHCCCCCCCHH
QASTNSNEPLPEIRNSDISTQATLQVGQSLLLGGFIQDTQIESQNKIPLLGDIPLLGGLF
HHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCEECCEECCCCCCCEEECCHHHHHHH
RSTDKQSHSVVRLFLIKAVPVNAGE
HCCCCHHHHHEEEEEEEEECCCCCC
>Mature Secondary Structure 
SLIYIMRKITGLILLFFATLLPYGKFSYGKAIPWQGEPFFIYSRGMTVSELLKDLGMNY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCC
GIPVVISSEINEHFTGKIRDKTPEKILSELAGRYNITWYYDGETLYFYPVQSIKREFISP
CCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCEEEEEEHHHHHHHHCCC
DGLAANTLVKYLQRGDVLAGKNCAIKAIPHLDTLEVKGVPICIERVKSVSKMLSEQVRHQ
CCCHHHHHHHHHHCCCEEECCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHC
NQNKETVKVFPLKYASAADSDYQYRDQNVRLPGLVSVLRELNQGNNLPLAGGNQPDGNQA
CCCCCEEEEEEEEECCCCCCCCEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SSPVFSADPRQNAVIIRDRQANMPIYRSLITQLDQRPIQIEISVTIIDVDAGDISQLGVD
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHCCCC
WSASASIGGTGVSFNSTFAKNNAEGFSTVIGDTGNFMVRLNALQKNSRARILSQPSVVTL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHEECCCCCEEEEEEECCCCCCCEEECCCCEEEE
NNIQAVLDKNVTFYTKLQGEKVAKLESVTSGSLLRVTPRMIETEGVQEVLLNLNIQDGQQ
CCHHHHHCCCCEEEEEECCCHHHHHHHCCCCCEEEECHHHHHHCCHHHHHHCCCCCCCHH
QASTNSNEPLPEIRNSDISTQATLQVGQSLLLGGFIQDTQIESQNKIPLLGDIPLLGGLF
HHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCEECCEECCCCCCCEEECCHHHHHHH
RSTDKQSHSVVRLFLIKAVPVNAGE
HCCCCHHHHHEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1860816 [H]