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The map label for this gene is frdD [H]

Identifier: 170026030

GI number: 170026030

Start: 4207151

End: 4207507

Strand: Direct

Name: frdD [H]

Synonym: YPK_3816

Alternate gene names: 170026030

Gene position: 4207151-4207507 (Clockwise)

Preceding gene: 170026029

Following gene: 170026033

Centisome position: 89.72

GC content: 49.58

Gene sequence:

>357_bases
ATGAATCAAGTCCCTAAACGCTCCGATGAACCGATCTTCTGGGGTCTGTTTGGTGCGGGTGGCATGTGGGGTGCAATTAT
TGCCCCTGTGATTATTCTGCTGGTCGCGATTTTGTTGCCATTGGGTGCATTCCCAGGCGACGCGCTGAGCTACGAACGCA
TTCTGGCATTTTGTCAGAGCTTTATTAGCCGGGTATTCCTGCTGCTGATGATCATTTTGCCTTTGTGGTGCGGTTTACAC
CGTATTCATCATGCAATGCATGATTTGAAAATCCACGTCCCGGCAGGGAAATGGGTATTCTATGGCCTTGCGGCAATCTT
GAGTGTGGTCACTTTTATCGGTGTACTGACGCTGTAG

Upstream 100 bases:

>100_bases
ATGGGTCCAGAGCCAATGATTAAGGCGCTATGGGTTGTGACTGTCGTGGCTAGCGCGATTATCCTGGCTGTCGCCTTACT
CTAACCCGGAGGAGAAAAAG

Downstream 100 bases:

>100_bases
CCGTAGTCACCACATGCCATATTCGCGGCCTGCTGTTCTGGCAGGCCGTTCTTTGGTTAAAGCGCTCAGTTCGGTTGCCA
AAATTTTACGACTCATTTGA

Product: fumarate reductase subunit D

Products: fumarate; reduced acceptor

Alternate protein names: Fumarate reductase 13 kDa hydrophobic protein [H]

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MNQVPKRSDEPIFWGLFGAGGMWGAIIAPVIILLVAILLPLGAFPGDALSYERILAFCQSFISRVFLLLMIILPLWCGLH
RIHHAMHDLKIHVPAGKWVFYGLAAILSVVTFIGVLTL

Sequences:

>Translated_118_residues
MNQVPKRSDEPIFWGLFGAGGMWGAIIAPVIILLVAILLPLGAFPGDALSYERILAFCQSFISRVFLLLMIILPLWCGLH
RIHHAMHDLKIHVPAGKWVFYGLAAILSVVTFIGVLTL
>Mature_118_residues
MNQVPKRSDEPIFWGLFGAGGMWGAIIAPVIILLVAILLPLGAFPGDALSYERILAFCQSFISRVFLLLMIILPLWCGLH
RIHHAMHDLKIHVPAGKWVFYGLAAILSVVTFIGVLTL

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane [H]

COG id: COG3080

COG function: function code C; Fumarate reductase subunit D

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdD family [H]

Homologues:

Organism=Escherichia coli, GI1790594, Length=118, Percent_Identity=84.7457627118644, Blast_Score=206, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003418
- ProDom:   PD015693 [H]

Pfam domain/function: PF02313 Fumarate_red_D [H]

EC number: 1.3.99.1

Molecular weight: Translated: 13020; Mature: 13020

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQVPKRSDEPIFWGLFGAGGMWGAIIAPVIILLVAILLPLGAFPGDALSYERILAFCQS
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FISRVFLLLMIILPLWCGLHRIHHAMHDLKIHVPAGKWVFYGLAAILSVVTFIGVLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQVPKRSDEPIFWGLFGAGGMWGAIIAPVIILLVAILLPLGAFPGDALSYERILAFCQS
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FISRVFLLLMIILPLWCGLHRIHHAMHDLKIHVPAGKWVFYGLAAILSVVTFIGVLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]