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The map label for this gene is can [H]

Identifier: 170025693

GI number: 170025693

Start: 3820237

End: 3821112

Strand: Direct

Name: can [H]

Synonym: YPK_3478

Alternate gene names: 170025693

Gene position: 3820237-3821112 (Clockwise)

Preceding gene: 170025689

Following gene: 170025696

Centisome position: 81.46

GC content: 44.75

Gene sequence:

>876_bases
ATGGGGCTCTTGGTGGTCCTGCGTACCCATGACGTATTTAACCCTCCCCACATGAGGGACGTTACGGGTAACATAAAAAA
TCAAACAGGCACCGAGAAGATATTACGCAGACAATATCGCGTTATTACCGAAACTACTGTTCCGATTTCAAAATCGGAAT
CCTTGCCGTATATTATTCTATCGCAACCCGAACACTACAGGCTATTTACATTGATGAAAGAAATAGAAAAGCTCATCGCG
AACAATCGAACTTGGTCAAACACCATTTGTAAAGATGATCCCGGTTTTTTTGAGCACTTGGCACAATCTCAGAAACCGCG
CTTCTTATGGATTGGTTGTTCAGACAGTCGCGTTCCCGCAGAGCAGTTAACTGGATTGAAATCAGGCGAGTTATTTGTTC
ACCGTAACGTTGCCAATCTGGTTATCCATACCGATCTTAACTGCCTATCGGTCGTCCAATACGCTATTGATGTTCTTCAG
GTAGAACACATTATTATCTGTGGCCACCTTGGCTGTGGTGGTGTTGAAGCGGCCATCAAAGGCGAAGAGATGGGGCTTAT
CGATAACTGGTTACTGCACATTCGGGACCTTTGGTATAAACACAGTTCATTGTTGGGTGAACTGCCACAAGAAGAACGCA
GTAATGTGTTGTGTCAGATAAACGTAGTAGAGCAAGTGTATAACCTTGGTCATTCAACCATTGTGCGTTCAGCCTGGAAG
CGCGGGCAAAAAGCCATGATCCACGGCTGGGTATATGGTATTGAAAATGGCCTGCTGCGTGATCTAGAAGTCTCAGCCAC
CAGCCTTGGTAGCCTGGAAATGGTGTATCGCAAAGCAATGGCTGAGTTATTACAAAACAATAAAGAAGACCATTAA

Upstream 100 bases:

>100_bases
CAGATCGATACCACGCAGTGCCTGAACGCCACCCATATAGGTTTTGGTCAACTGCGTTATTTCCAGTGCATATGTCATAA
GTAAAAAGGAACCTTATTCA

Downstream 100 bases:

>100_bases
GTCGCTCTGGGAGGGTACGTTAAAACGCGCCCTCTCCCACAAACCCTTCCGCTAAATTAAGCGTCCCAGCGCGCAAGAAC
CGGAGCGTACATGCAGTACG

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MGLLVVLRTHDVFNPPHMRDVTGNIKNQTGTEKILRRQYRVITETTVPISKSESLPYIILSQPEHYRLFTLMKEIEKLIA
NNRTWSNTICKDDPGFFEHLAQSQKPRFLWIGCSDSRVPAEQLTGLKSGELFVHRNVANLVIHTDLNCLSVVQYAIDVLQ
VEHIIICGHLGCGGVEAAIKGEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQINVVEQVYNLGHSTIVRSAWK
RGQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMAELLQNNKEDH

Sequences:

>Translated_291_residues
MGLLVVLRTHDVFNPPHMRDVTGNIKNQTGTEKILRRQYRVITETTVPISKSESLPYIILSQPEHYRLFTLMKEIEKLIA
NNRTWSNTICKDDPGFFEHLAQSQKPRFLWIGCSDSRVPAEQLTGLKSGELFVHRNVANLVIHTDLNCLSVVQYAIDVLQ
VEHIIICGHLGCGGVEAAIKGEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQINVVEQVYNLGHSTIVRSAWK
RGQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMAELLQNNKEDH
>Mature_290_residues
GLLVVLRTHDVFNPPHMRDVTGNIKNQTGTEKILRRQYRVITETTVPISKSESLPYIILSQPEHYRLFTLMKEIEKLIAN
NRTWSNTICKDDPGFFEHLAQSQKPRFLWIGCSDSRVPAEQLTGLKSGELFVHRNVANLVIHTDLNCLSVVQYAIDVLQV
EHIIICGHLGCGGVEAAIKGEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQINVVEQVYNLGHSTIVRSAWKR
GQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMAELLQNNKEDH

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=212, Percent_Identity=73.1132075471698, Blast_Score=340, Evalue=4e-95,
Organism=Escherichia coli, GI1786534, Length=174, Percent_Identity=35.0574712643678, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324292, Length=216, Percent_Identity=31.0185185185185, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 33117; Mature: 32985

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLVVLRTHDVFNPPHMRDVTGNIKNQTGTEKILRRQYRVITETTVPISKSESLPYIIL
CCEEEEEEECCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
SQPEHYRLFTLMKEIEKLIANNRTWSNTICKDDPGFFEHLAQSQKPRFLWIGCSDSRVPA
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCH
EQLTGLKSGELFVHRNVANLVIHTDLNCLSVVQYAIDVLQVEHIIICGHLGCGGVEAAIK
HHHCCCCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHCEEEEEECCCCCCCHHEEC
GEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQINVVEQVYNLGHSTIVRSAWK
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEEHHHHHHHCCHHHHHHHHHH
RGQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMAELLQNNKEDH
CCCHHHHHHHHHHHCCCCHHHHECCHHCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GLLVVLRTHDVFNPPHMRDVTGNIKNQTGTEKILRRQYRVITETTVPISKSESLPYIIL
CEEEEEEECCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
SQPEHYRLFTLMKEIEKLIANNRTWSNTICKDDPGFFEHLAQSQKPRFLWIGCSDSRVPA
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCH
EQLTGLKSGELFVHRNVANLVIHTDLNCLSVVQYAIDVLQVEHIIICGHLGCGGVEAAIK
HHHCCCCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHHHCEEEEEECCCCCCCHHEEC
GEEMGLIDNWLLHIRDLWYKHSSLLGELPQEERSNVLCQINVVEQVYNLGHSTIVRSAWK
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEEEEEEHHHHHHHCCHHHHHHHHHH
RGQKAMIHGWVYGIENGLLRDLEVSATSLGSLEMVYRKAMAELLQNNKEDH
CCCHHHHHHHHHHHCCCCHHHHECCHHCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]