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The map label for this gene is yafC [H]

Identifier: 170025127

GI number: 170025127

Start: 3199594

End: 3200505

Strand: Direct

Name: yafC [H]

Synonym: YPK_2905

Alternate gene names: 170025127

Gene position: 3199594-3200505 (Clockwise)

Preceding gene: 170025125

Following gene: 170025131

Centisome position: 68.23

GC content: 54.06

Gene sequence:

>912_bases
ATGAGAAGAACAGATCATCTTGGCGGTATCACTGCTTTTGTCACCACGGCTCAGCAGGGAAGTTTCACCGCTGCCGCAGA
AAAACTGGGACTGACTAAATCTGCTGTTGGGAAAAGTGTCAGTCGCCTTGAGGATCGTCTCGGGCTGAAGCTATTTCAGC
GTTCGACACGACGGCTCAGCCTGACACCGGATGGCGAGCGATTTCTTGCCAGTTGTCAGAGTGCGATAGACATCCTGGAA
CAGGCTGAAGCGGAACTGATGTCTCATATCTGCCAGCCTTCAGGGCGGCTCAGGGTTGATTTACCGGCCGCTTTTGGGCG
ACAGCGTATACTTCCTATCCTGCTGGACATTATCCGACTTTACCCAGAGCTGGCTCTGACCGTCACATTCAGTGAGCGTT
TTGTCGACCTTATTGAGGAAGGCATTGACCTTGTCATTCGCATTGGGGAACTGGCGGACAGCAGCGGTCTGGTCGCCAGA
AGGCTCACGACGCAAAAACTGGTTATCTGCGCTTCACCGGATTATCTGCTTTATCACGGCGAGCCTGTCAGTACGGATGA
ACTGAGCCAGCATCAGTGCGTTGTCGGATTTCGCCGCAGTCAGCCTATTTCCTGGTTGCTGAAGGAGAGTGACGGCCAAA
TCAGTCGCTTTGCGCCACCTCCTACACATGAATTTGGTGATGGTGACGCTATGCTTGCTGCCACGCTGGCAGGGGGCGGG
TTGTCACAGTTACCCTTGTGGCTGGTTGGTAAATACCTTGAGAGTGGTGAACTGCGGGAAGTTCTTCCGGGGCATTCCGG
AGGTGAAATGCCGATCAGTGCGCTGTGGCCGAAAAACCGTCAACTGCTGCCTAAAATACGCTACGTTGTGGACACGCTGG
TTAAGGCAGCAGAAGACGGCCTCCTCGACTGA

Upstream 100 bases:

>100_bases
AGGAGATGCATGGAAACTGAACCTGGCCCTGGCTGAAACAGCGGGCCGCTATCTGACAATCCGACATACCACGCAGGACG
GAGACGTCTGACGGGAAATT

Downstream 100 bases:

>100_bases
TTATGCCTGGGTATCGGACCAGACCGGATAGTCTGTATACCCTTTTTCATCCCCGCCATACATTGTTGCCCGATCAACCT
GATTTAATGGCCAGTCATTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MRRTDHLGGITAFVTTAQQGSFTAAAEKLGLTKSAVGKSVSRLEDRLGLKLFQRSTRRLSLTPDGERFLASCQSAIDILE
QAEAELMSHICQPSGRLRVDLPAAFGRQRILPILLDIIRLYPELALTVTFSERFVDLIEEGIDLVIRIGELADSSGLVAR
RLTTQKLVICASPDYLLYHGEPVSTDELSQHQCVVGFRRSQPISWLLKESDGQISRFAPPPTHEFGDGDAMLAATLAGGG
LSQLPLWLVGKYLESGELREVLPGHSGGEMPISALWPKNRQLLPKIRYVVDTLVKAAEDGLLD

Sequences:

>Translated_303_residues
MRRTDHLGGITAFVTTAQQGSFTAAAEKLGLTKSAVGKSVSRLEDRLGLKLFQRSTRRLSLTPDGERFLASCQSAIDILE
QAEAELMSHICQPSGRLRVDLPAAFGRQRILPILLDIIRLYPELALTVTFSERFVDLIEEGIDLVIRIGELADSSGLVAR
RLTTQKLVICASPDYLLYHGEPVSTDELSQHQCVVGFRRSQPISWLLKESDGQISRFAPPPTHEFGDGDAMLAATLAGGG
LSQLPLWLVGKYLESGELREVLPGHSGGEMPISALWPKNRQLLPKIRYVVDTLVKAAEDGLLD
>Mature_303_residues
MRRTDHLGGITAFVTTAQQGSFTAAAEKLGLTKSAVGKSVSRLEDRLGLKLFQRSTRRLSLTPDGERFLASCQSAIDILE
QAEAELMSHICQPSGRLRVDLPAAFGRQRILPILLDIIRLYPELALTVTFSERFVDLIEEGIDLVIRIGELADSSGLVAR
RLTTQKLVICASPDYLLYHGEPVSTDELSQHQCVVGFRRSQPISWLLKESDGQISRFAPPPTHEFGDGDAMLAATLAGGG
LSQLPLWLVGKYLESGELREVLPGHSGGEMPISALWPKNRQLLPKIRYVVDTLVKAAEDGLLD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=305, Percent_Identity=37.0491803278689, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=30.4347826086957, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI87081978, Length=260, Percent_Identity=33.8461538461538, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=29.757785467128, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1789440, Length=302, Percent_Identity=32.7814569536424, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1787128, Length=280, Percent_Identity=28.9285714285714, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787589, Length=264, Percent_Identity=27.6515151515151, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788706, Length=174, Percent_Identity=32.7586206896552, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786448, Length=254, Percent_Identity=27.5590551181102, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789173, Length=192, Percent_Identity=31.25, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786508, Length=251, Percent_Identity=26.6932270916335, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787806, Length=272, Percent_Identity=25, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082132, Length=253, Percent_Identity=26.4822134387352, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787879, Length=291, Percent_Identity=24.3986254295533, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788481, Length=262, Percent_Identity=27.0992366412214, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33211; Mature: 33211

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRTDHLGGITAFVTTAQQGSFTAAAEKLGLTKSAVGKSVSRLEDRLGLKLFQRSTRRLS
CCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LTPDGERFLASCQSAIDILEQAEAELMSHICQPSGRLRVDLPAAFGRQRILPILLDIIRL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHCCHHHHHHHHHHHHHH
YPELALTVTFSERFVDLIEEGIDLVIRIGELADSSGLVARRLTTQKLVICASPDYLLYHG
CHHHEEEEEHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHCCEEEEEEECCCEEEECC
EPVSTDELSQHQCVVGFRRSQPISWLLKESDGQISRFAPPPTHEFGDGDAMLAATLAGGG
CCCCHHHHCCCHHEEEECCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCEEHHHHCCCC
LSQLPLWLVGKYLESGELREVLPGHSGGEMPISALWPKNRQLLPKIRYVVDTLVKAAEDG
HHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCC
LLD
CCC
>Mature Secondary Structure
MRRTDHLGGITAFVTTAQQGSFTAAAEKLGLTKSAVGKSVSRLEDRLGLKLFQRSTRRLS
CCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LTPDGERFLASCQSAIDILEQAEAELMSHICQPSGRLRVDLPAAFGRQRILPILLDIIRL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHCCHHHHHHHHHHHHHH
YPELALTVTFSERFVDLIEEGIDLVIRIGELADSSGLVARRLTTQKLVICASPDYLLYHG
CHHHEEEEEHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHCCEEEEEEECCCEEEECC
EPVSTDELSQHQCVVGFRRSQPISWLLKESDGQISRFAPPPTHEFGDGDAMLAATLAGGG
CCCCHHHHCCCHHEEEECCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCEEHHHHCCCC
LSQLPLWLVGKYLESGELREVLPGHSGGEMPISALWPKNRQLLPKIRYVVDTLVKAAEDG
HHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCC
LLD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]