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The map label for this gene is tcp [H]

Identifier: 170025057

GI number: 170025057

Start: 3116566

End: 3118353

Strand: Direct

Name: tcp [H]

Synonym: YPK_2833

Alternate gene names: 170025057

Gene position: 3116566-3118353 (Clockwise)

Preceding gene: 170025055

Following gene: 170025059

Centisome position: 66.46

GC content: 50.39

Gene sequence:

>1788_bases
ATGCTTGATTCCATTCGCTCACGTATTTTGGCAGCCTGTATTATCATCGTTGCGGGTTCGCTCGCCATTAACACCTTCCT
CAACTATTCCGTTGCCAATAAATATAATAACAGCGCCATCGATAATACCCTGACGGCACTCACTGTTAGCCACAGTGTCA
GCATTGCTGAATGGGTGGCATCCAAAACACAAATGATTATGTCGCTCAAAGACAGCGCATTGACCGCCGATCCACTCGCA
GCACTAAAGCAAGTGGCTGCAGCAGGCGGCTTTATTAATGTCTATATTGGCTATGCCGATAAAACGGCTATTTTTTCCAA
CCCGGATGGCATTCCTGCCGATTATGACCCCACCGGACGCCCGTGGTATCTACAAGCCGTGAATGCAGGCAAGCCAGTGG
TGACACCTCCGTATATCGATGCGGGGACCCAGCAGTTAGTCGTCACATTTGCATGGTCCATCGTTCAGGATGGGGTTCTT
AAAGGCGTGATCGCTGCCGATGTCACTATGGGAAGTGTCATTGCCAATGTAAATGCTATACACCCAACCGATAATAGCTT
CGGAATGCTAATCGGGGCTGATGGCACAATCATCGCCCATCCTGAGACGCTGCTGACCCTTAAGCCATTGGCCGATATCG
CGCCGAACCTGAATTTACAAACCCTGCTGACGGCAACGGTACCTGTTTCAACGGATATTAGCGGCAGCAGCAAATTATTG
CTCGCCCAGGCGGTCCCTGGAACCCAGTGGTTTACCGTCGTTGCGCTGGATAAATCTCAAGCAACTGCGGGAATACATTC
ATTATTAACGACATCATTAGTAACATTGGTGATAATTATCTTCATCTCGGCGGGGGTGATAGCGCTGATCACCCAACGCG
CCCTGACACCATTAACACATATTCAGCAAGCGATGGATGCTATCAGTTCCGGCTCGGCAGACCTCACTCAACGCCTCCCG
ATCGAAGGCCGTGATGAAGTAGCACAGATTGCCCGTTCATTTAATCAGTTTGCGGATAAGCTCAGTCTGGTTATGGCTCA
AATCCGTGGTACCAGCGAGTCTGTCCGGGTAGCAGCGAATGAAATCGCAGCAGGCAACCAAGACTTATCGGGTAGAACAG
AATCAGCCGCCGCCAGTTTGCAGCAAACCTCAGCAGCGCTGGAACAAATTTCGGCAACCGTCGCTCAATCAGCCAGTGCC
GCACGGCAAGCTAACAACGCGGTATTTTCTGCCTCTGAGGATGCTTCTCGCGGTGGCGACGTTATCACTAAAGTCATCAC
AACGATGGAGTCAATTGAAAAGGCCTCGGGAAAAATTGGCGATATCACTAGCGTCATTGATGGCATTGCTTTCCAAACAA
ATATTCTGGCACTGAATGCTGCCGTCGAGGCCGCTCGAGCAGGAGAACAAGGACGAGGTTTTGCCGTGGTTGCAGGCGAA
GTCCGTATACTGGCACAACGCAGTGCACAAGCGGCTAAAGAGATAAAAGCCCTGATCGAATCGACGGTCAGCAGTGTGGC
ATCCGGCTCCAGCCAAGTGCGCCAAGCCAGTAATGCCATGACCGATATTGTCAGTAGTGTCTCTGATGTCACGACCATTA
TGTCGGAGATCACCAATGCCGCTGATGAACAAATGCGTGGTATTCACGAAATAAATAGTGCAGTAGCGCAATTAGATACA
ATGGTGCAACAGAATGCCGCACTGGTGCAGGAGTCAACGGCCGCTTCAGCCGCCTTACAAGCTCAGGCCGCTGATTTAAC
TGATACCGTTAATCAATTTAAGATCTAA

Upstream 100 bases:

>100_bases
ACAGTAGTCATTAATTACAGTTTATTACTGTGACTCAGCTCAAGTTTTTTCCTGCCAAGCCGTTACTTGAATCATGTTTT
CCTTTCTATTAGGACACTCT

Downstream 100 bases:

>100_bases
CGCGCTGCTGCTATCAACCAGAACCGCCGTCATTCAGTTCCAGCAGGTTATTCATCCACCCGCTGGAACGTGACTATTCC
AGTATGATCCGTGCACCTAT

Product: Cache sensor-containing methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MLDSIRSRILAACIIIVAGSLAINTFLNYSVANKYNNSAIDNTLTALTVSHSVSIAEWVASKTQMIMSLKDSALTADPLA
ALKQVAAAGGFINVYIGYADKTAIFSNPDGIPADYDPTGRPWYLQAVNAGKPVVTPPYIDAGTQQLVVTFAWSIVQDGVL
KGVIAADVTMGSVIANVNAIHPTDNSFGMLIGADGTIIAHPETLLTLKPLADIAPNLNLQTLLTATVPVSTDISGSSKLL
LAQAVPGTQWFTVVALDKSQATAGIHSLLTTSLVTLVIIIFISAGVIALITQRALTPLTHIQQAMDAISSGSADLTQRLP
IEGRDEVAQIARSFNQFADKLSLVMAQIRGTSESVRVAANEIAAGNQDLSGRTESAAASLQQTSAALEQISATVAQSASA
ARQANNAVFSASEDASRGGDVITKVITTMESIEKASGKIGDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRILAQRSAQAAKEIKALIESTVSSVASGSSQVRQASNAMTDIVSSVSDVTTIMSEITNAADEQMRGIHEINSAVAQLDT
MVQQNAALVQESTAASAALQAQAADLTDTVNQFKI

Sequences:

>Translated_595_residues
MLDSIRSRILAACIIIVAGSLAINTFLNYSVANKYNNSAIDNTLTALTVSHSVSIAEWVASKTQMIMSLKDSALTADPLA
ALKQVAAAGGFINVYIGYADKTAIFSNPDGIPADYDPTGRPWYLQAVNAGKPVVTPPYIDAGTQQLVVTFAWSIVQDGVL
KGVIAADVTMGSVIANVNAIHPTDNSFGMLIGADGTIIAHPETLLTLKPLADIAPNLNLQTLLTATVPVSTDISGSSKLL
LAQAVPGTQWFTVVALDKSQATAGIHSLLTTSLVTLVIIIFISAGVIALITQRALTPLTHIQQAMDAISSGSADLTQRLP
IEGRDEVAQIARSFNQFADKLSLVMAQIRGTSESVRVAANEIAAGNQDLSGRTESAAASLQQTSAALEQISATVAQSASA
ARQANNAVFSASEDASRGGDVITKVITTMESIEKASGKIGDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRILAQRSAQAAKEIKALIESTVSSVASGSSQVRQASNAMTDIVSSVSDVTTIMSEITNAADEQMRGIHEINSAVAQLDT
MVQQNAALVQESTAASAALQAQAADLTDTVNQFKI
>Mature_595_residues
MLDSIRSRILAACIIIVAGSLAINTFLNYSVANKYNNSAIDNTLTALTVSHSVSIAEWVASKTQMIMSLKDSALTADPLA
ALKQVAAAGGFINVYIGYADKTAIFSNPDGIPADYDPTGRPWYLQAVNAGKPVVTPPYIDAGTQQLVVTFAWSIVQDGVL
KGVIAADVTMGSVIANVNAIHPTDNSFGMLIGADGTIIAHPETLLTLKPLADIAPNLNLQTLLTATVPVSTDISGSSKLL
LAQAVPGTQWFTVVALDKSQATAGIHSLLTTSLVTLVIIIFISAGVIALITQRALTPLTHIQQAMDAISSGSADLTQRLP
IEGRDEVAQIARSFNQFADKLSLVMAQIRGTSESVRVAANEIAAGNQDLSGRTESAAASLQQTSAALEQISATVAQSASA
ARQANNAVFSASEDASRGGDVITKVITTMESIEKASGKIGDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRILAQRSAQAAKEIKALIESTVSSVASGSSQVRQASNAMTDIVSSVSDVTTIMSEITNAADEQMRGIHEINSAVAQLDT
MVQQNAALVQESTAASAALQAQAADLTDTVNQFKI

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=328, Percent_Identity=51.219512195122, Blast_Score=268, Evalue=5e-73,
Organism=Escherichia coli, GI1787690, Length=325, Percent_Identity=47.6923076923077, Blast_Score=267, Evalue=2e-72,
Organism=Escherichia coli, GI1788195, Length=306, Percent_Identity=53.5947712418301, Blast_Score=265, Evalue=5e-72,
Organism=Escherichia coli, GI1788194, Length=340, Percent_Identity=48.5294117647059, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI1789453, Length=318, Percent_Identity=38.0503144654088, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 61788; Mature: 61788

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDSIRSRILAACIIIVAGSLAINTFLNYSVANKYNNSAIDNTLTALTVSHSVSIAEWVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECCCHHHHHHHH
SKTQMIMSLKDSALTADPLAALKQVAAAGGFINVYIGYADKTAIFSNPDGIPADYDPTGR
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCC
PWYLQAVNAGKPVVTPPYIDAGTQQLVVTFAWSIVQDGVLKGVIAADVTMGSVIANVNAI
CEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
HPTDNSFGMLIGADGTIIAHPETLLTLKPLADIAPNLNLQTLLTATVPVSTDISGSSKLL
CCCCCCCEEEEECCCEEEECCHHHEEECCHHHHCCCCCHHEEEEEECCCCCCCCCCCCEE
LAQAVPGTQWFTVVALDKSQATAGIHSLLTTSLVTLVIIIFISAGVIALITQRALTPLTH
EEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQQAMDAISSGSADLTQRLPIEGRDEVAQIARSFNQFADKLSLVMAQIRGTSESVRVAAN
HHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EIAAGNQDLSGRTESAAASLQQTSAALEQISATVAQSASAARQANNAVFSASEDASRGGD
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHH
VITKVITTMESIEKASGKIGDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCEEEEECC
VRILAQRSAQAAKEIKALIESTVSSVASGSSQVRQASNAMTDIVSSVSDVTTIMSEITNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADEQMRGIHEINSAVAQLDTMVQQNAALVQESTAASAALQAQAADLTDTVNQFKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDSIRSRILAACIIIVAGSLAINTFLNYSVANKYNNSAIDNTLTALTVSHSVSIAEWVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHEEECCCHHHHHHHH
SKTQMIMSLKDSALTADPLAALKQVAAAGGFINVYIGYADKTAIFSNPDGIPADYDPTGR
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCCEEEECCCCCCCCCCCCCCC
PWYLQAVNAGKPVVTPPYIDAGTQQLVVTFAWSIVQDGVLKGVIAADVTMGSVIANVNAI
CEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
HPTDNSFGMLIGADGTIIAHPETLLTLKPLADIAPNLNLQTLLTATVPVSTDISGSSKLL
CCCCCCCEEEEECCCEEEECCHHHEEECCHHHHCCCCCHHEEEEEECCCCCCCCCCCCEE
LAQAVPGTQWFTVVALDKSQATAGIHSLLTTSLVTLVIIIFISAGVIALITQRALTPLTH
EEECCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQQAMDAISSGSADLTQRLPIEGRDEVAQIARSFNQFADKLSLVMAQIRGTSESVRVAAN
HHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EIAAGNQDLSGRTESAAASLQQTSAALEQISATVAQSASAARQANNAVFSASEDASRGGD
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHH
VITKVITTMESIEKASGKIGDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCEEEEECC
VRILAQRSAQAAKEIKALIESTVSSVASGSSQVRQASNAMTDIVSSVSDVTTIMSEITNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADEQMRGIHEINSAVAQLDTMVQQNAALVQESTAASAALQAQAADLTDTVNQFKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]