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The map label for this gene is yeiR [H]

Identifier: 170025007

GI number: 170025007

Start: 3070231

End: 3071214

Strand: Direct

Name: yeiR [H]

Synonym: YPK_2782

Alternate gene names: 170025007

Gene position: 3070231-3071214 (Clockwise)

Preceding gene: 170025004

Following gene: 170025008

Centisome position: 65.47

GC content: 49.09

Gene sequence:

>984_bases
ATGACAAAGACCAATTTAATTACCGGGTTTTTAGGTTGTGGCAAAACCACGACTATCCGGCACTTACTCGCACAGAAGCC
GGAACATGAAAAATGGGCGGTGCTGGTCAATGAATTTGGTGAGATTGGTATTGATGGCGCTCTGTTGGCGGATAGCGGTG
CTGTCTTAAAAGAGATCCCAGGGGGCTGCATGTGCTGTGTTAATGGGCTACCGATGCAAATTGGCCTGAACATGCTGTTG
CAGCAGGCAAAACTAGATCGCCTGCTCATTGAGCCAACCGGGCTGGGCCACCCGAAACAAATTCTGTCATTATTAACGTC
TGATATTTATCAGCCTTGGATTGACTTACGCGCCACACTTTGTCTGCTGGATGCCCGCCAACTGAGTGAACCCCGCTATA
CCGAAAATGAAAATTTCCGTGACCAACTGGCGGCGGCAGATATCATTGTGGCCAACAAGCAAGACACTTACCGCTCGGCC
GATAACGCGGTGTTACAACAATGGCAACAAAAGCAGCCATTATCGCGGCCGCTGTATCATAGCGAATATGGCAAACTCGA
CGTGGCCCTGCTCGACCAACCACACCGTAATAAAGACGAACTTCCTTCTGGTACGCATCATCACGGCACATCACAGCCAA
AAGGATTAGCCGCATTACGTCTGAAAGGGGCCGAACCCTGGCGTCGGGCATTAAATCGGGGGCAAGGGTATCTGAGCTGC
GGCTGGGTATTTGATGCCAACACCGTTTTTGATACCGTGCCATTATTGGAGTGGGTACGATTGAACCCAGCAGAACGGGT
AAAAGGTGTCATGCGCATCCCGGAAGGAACCTTGATGGTTAATCGACAAGGTAATGACTTACAAATAGACACTCGCCAAA
TACCCCCGCTGGATAGCCGCATTGAATTGATTAGCGCCACTGATATTGATTGGAACGTATTGCAACATGATTTATTAAAA
ATTCGTTTACGTAACGGGGTATGA

Upstream 100 bases:

>100_bases
AAGCCTAATTGGCCTTATTTCCTTTCTGGTTGAAAGGGTAATAAATAGCCATATAATTTGTAAATCATATAAAAATATTT
TTGTATTTTGGAGATCCAGC

Downstream 100 bases:

>100_bases
TGTCTCCCCGTTTTTATTTTCTTCCCGTTGTGTACATTTTTAATTTATAGGTTGCCGCATGACTCGTCGTAATTTACCGA
CAATATTGCTCCTCAATTTA

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTKTNLITGFLGCGKTTTIRHLLAQKPEHEKWAVLVNEFGEIGIDGALLADSGAVLKEIPGGCMCCVNGLPMQIGLNMLL
QQAKLDRLLIEPTGLGHPKQILSLLTSDIYQPWIDLRATLCLLDARQLSEPRYTENENFRDQLAAADIIVANKQDTYRSA
DNAVLQQWQQKQPLSRPLYHSEYGKLDVALLDQPHRNKDELPSGTHHHGTSQPKGLAALRLKGAEPWRRALNRGQGYLSC
GWVFDANTVFDTVPLLEWVRLNPAERVKGVMRIPEGTLMVNRQGNDLQIDTRQIPPLDSRIELISATDIDWNVLQHDLLK
IRLRNGV

Sequences:

>Translated_327_residues
MTKTNLITGFLGCGKTTTIRHLLAQKPEHEKWAVLVNEFGEIGIDGALLADSGAVLKEIPGGCMCCVNGLPMQIGLNMLL
QQAKLDRLLIEPTGLGHPKQILSLLTSDIYQPWIDLRATLCLLDARQLSEPRYTENENFRDQLAAADIIVANKQDTYRSA
DNAVLQQWQQKQPLSRPLYHSEYGKLDVALLDQPHRNKDELPSGTHHHGTSQPKGLAALRLKGAEPWRRALNRGQGYLSC
GWVFDANTVFDTVPLLEWVRLNPAERVKGVMRIPEGTLMVNRQGNDLQIDTRQIPPLDSRIELISATDIDWNVLQHDLLK
IRLRNGV
>Mature_326_residues
TKTNLITGFLGCGKTTTIRHLLAQKPEHEKWAVLVNEFGEIGIDGALLADSGAVLKEIPGGCMCCVNGLPMQIGLNMLLQ
QAKLDRLLIEPTGLGHPKQILSLLTSDIYQPWIDLRATLCLLDARQLSEPRYTENENFRDQLAAADIIVANKQDTYRSAD
NAVLQQWQQKQPLSRPLYHSEYGKLDVALLDQPHRNKDELPSGTHHHGTSQPKGLAALRLKGAEPWRRALNRGQGYLSCG
WVFDANTVFDTVPLLEWVRLNPAERVKGVMRIPEGTLMVNRQGNDLQIDTRQIPPLDSRIELISATDIDWNVLQHDLLKI
RLRNGV

Specific function: Unknown

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=175, Percent_Identity=33.1428571428571, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI223941779, Length=175, Percent_Identity=33.1428571428571, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI33469141, Length=174, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI148727351, Length=174, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI146231952, Length=174, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788499, Length=324, Percent_Identity=67.5925925925926, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI87082430, Length=194, Percent_Identity=30.9278350515464, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 36650; Mature: 36518

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTNLITGFLGCGKTTTIRHLLAQKPEHEKWAVLVNEFGEIGIDGALLADSGAVLKEIP
CCCCCEEEEHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHCC
GGCMCCVNGLPMQIGLNMLLQQAKLDRLLIEPTGLGHPKQILSLLTSDIYQPWIDLRATL
CCEEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
CLLDARQLSEPRYTENENFRDQLAAADIIVANKQDTYRSADNAVLQQWQQKQPLSRPLYH
HHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
SEYGKLDVALLDQPHRNKDELPSGTHHHGTSQPKGLAALRLKGAEPWRRALNRGQGYLSC
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCEEEE
GWVFDANTVFDTVPLLEWVRLNPAERVKGVMRIPEGTLMVNRQGNDLQIDTRQIPPLDSR
EEEEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCC
IELISATDIDWNVLQHDLLKIRLRNGV
EEEEEECCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKTNLITGFLGCGKTTTIRHLLAQKPEHEKWAVLVNEFGEIGIDGALLADSGAVLKEIP
CCCCEEEEHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHCC
GGCMCCVNGLPMQIGLNMLLQQAKLDRLLIEPTGLGHPKQILSLLTSDIYQPWIDLRATL
CCEEEECCCCCHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
CLLDARQLSEPRYTENENFRDQLAAADIIVANKQDTYRSADNAVLQQWQQKQPLSRPLYH
HHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
SEYGKLDVALLDQPHRNKDELPSGTHHHGTSQPKGLAALRLKGAEPWRRALNRGQGYLSC
CCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHCCCCEEEE
GWVFDANTVFDTVPLLEWVRLNPAERVKGVMRIPEGTLMVNRQGNDLQIDTRQIPPLDSR
EEEEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCEEEECCCCCCCCCC
IELISATDIDWNVLQHDLLKIRLRNGV
EEEEEECCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]