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The map label for this gene is uxuR [H]

Identifier: 170025005

GI number: 170025005

Start: 3068680

End: 3069423

Strand: Reverse

Name: uxuR [H]

Synonym: YPK_2780

Alternate gene names: 170025005

Gene position: 3069423-3068680 (Counterclockwise)

Preceding gene: 170025006

Following gene: 170025003

Centisome position: 65.45

GC content: 50.27

Gene sequence:

>744_bases
ATGCGGTTATATCAGGAAGTGGGCAGCCAACTGCGGGAAGCGATTGTCAGTGGGCGATACTCAGTGGGCGATCGTTTACC
ACCGGAGCGTGATATTGCCGAAAATTTCAGTGTCAGCCGTAGTGTGGTGCGTGAAGCCCTGATTATGCTCGAGCTGGAGA
AGCTGGTAGAAGTACGCAAAGGCTCCGGTGTTTACGTGGTGAATGTGCCCACGATGTCGCTTAATGGTGAGTCGGCTACG
TCAATCGATAGTGGCTACGGCCCGTTTGAACTGCTACAAGCCCGGCAATTGTTAGAGAGCGAAGTCGCGGCTTTTGCCGC
AATGCAAGCCACCAAAGCCGATATCATTAAAATGCGTAATGCTATTGAGCAGGGAAAAGCCGCACTGACGGCTGGCGCGA
TAGATGAAAGCGCTGATGAGTTGTTTCATTGTTTGTTAGCGCAATCGACACAAAATAGTGTGCTGGCCAATATGGTTGCG
CAGACCTGGCAAGTCCGGAAAAGTAGTGCAATGTGGCAGGGGGCGCATAGTCATACCGCCGATTTTAGCTACCGTTGGCA
ATGGTTGGATGATCACCAAAAAATCTTGCAAGCCGTGCTTCGCCGCGACAGTAAAGCCGCTAAGCAGGCCATGTGGCAGC
ATTTGGAGAATGTAAAATTGAAGTTGCTGGAGATCTCTGATGCTGACCATCCAGATTTTGATGGCTACTTATTTGAGTCT
GCGCCATATCAGATTGAAGAGTAA

Upstream 100 bases:

>100_bases
TTGTTTGACCACATGATATACTCGACGCCATTCATACACCCTTTTGGTCAGATCAATTTGGTATTTTCTACGCCAATGTC
TGATGCAGGAAATTAAGGTT

Downstream 100 bases:

>100_bases
AAGATAACGTAAAAACCAACCGTAGTCGCACCAAGAGTACTAACGTCAACAGAACTAATATCAACAGAACTAAACGCCAA
CAATACCGATGAGCTGAATA

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MRLYQEVGSQLREAIVSGRYSVGDRLPPERDIAENFSVSRSVVREALIMLELEKLVEVRKGSGVYVVNVPTMSLNGESAT
SIDSGYGPFELLQARQLLESEVAAFAAMQATKADIIKMRNAIEQGKAALTAGAIDESADELFHCLLAQSTQNSVLANMVA
QTWQVRKSSAMWQGAHSHTADFSYRWQWLDDHQKILQAVLRRDSKAAKQAMWQHLENVKLKLLEISDADHPDFDGYLFES
APYQIEE

Sequences:

>Translated_247_residues
MRLYQEVGSQLREAIVSGRYSVGDRLPPERDIAENFSVSRSVVREALIMLELEKLVEVRKGSGVYVVNVPTMSLNGESAT
SIDSGYGPFELLQARQLLESEVAAFAAMQATKADIIKMRNAIEQGKAALTAGAIDESADELFHCLLAQSTQNSVLANMVA
QTWQVRKSSAMWQGAHSHTADFSYRWQWLDDHQKILQAVLRRDSKAAKQAMWQHLENVKLKLLEISDADHPDFDGYLFES
APYQIEE
>Mature_247_residues
MRLYQEVGSQLREAIVSGRYSVGDRLPPERDIAENFSVSRSVVREALIMLELEKLVEVRKGSGVYVVNVPTMSLNGESAT
SIDSGYGPFELLQARQLLESEVAAFAAMQATKADIIKMRNAIEQGKAALTAGAIDESADELFHCLLAQSTQNSVLANMVA
QTWQVRKSSAMWQGAHSHTADFSYRWQWLDDHQKILQAVLRRDSKAAKQAMWQHLENVKLKLLEISDADHPDFDGYLFES
APYQIEE

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=243, Percent_Identity=51.8518518518518, Blast_Score=254, Evalue=4e-69,
Organism=Escherichia coli, GI87082208, Length=243, Percent_Identity=48.1481481481481, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1790032, Length=229, Percent_Identity=29.2576419213974, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789353, Length=240, Percent_Identity=27.5, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994955, Length=225, Percent_Identity=25.3333333333333, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789621, Length=226, Percent_Identity=28.3185840707965, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786303, Length=156, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27675; Mature: 27675

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLYQEVGSQLREAIVSGRYSVGDRLPPERDIAENFSVSRSVVREALIMLELEKLVEVRK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSGVYVVNVPTMSLNGESATSIDSGYGPFELLQARQLLESEVAAFAAMQATKADIIKMRN
CCCEEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIEQGKAALTAGAIDESADELFHCLLAQSTQNSVLANMVAQTWQVRKSSAMWQGAHSHTA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DFSYRWQWLDDHQKILQAVLRRDSKAAKQAMWQHLENVKLKLLEISDADHPDFDGYLFES
CCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEECC
APYQIEE
CCCCCCC
>Mature Secondary Structure
MRLYQEVGSQLREAIVSGRYSVGDRLPPERDIAENFSVSRSVVREALIMLELEKLVEVRK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSGVYVVNVPTMSLNGESATSIDSGYGPFELLQARQLLESEVAAFAAMQATKADIIKMRN
CCCEEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIEQGKAALTAGAIDESADELFHCLLAQSTQNSVLANMVAQTWQVRKSSAMWQGAHSHTA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DFSYRWQWLDDHQKILQAVLRRDSKAAKQAMWQHLENVKLKLLEISDADHPDFDGYLFES
CCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCEEECC
APYQIEE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]