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The map label for this gene is mukE [H]

Identifier: 170024881

GI number: 170024881

Start: 2921880

End: 2922608

Strand: Reverse

Name: mukE [H]

Synonym: YPK_2656

Alternate gene names: 170024881

Gene position: 2922608-2921880 (Counterclockwise)

Preceding gene: 170024882

Following gene: 170024880

Centisome position: 62.32

GC content: 47.05

Gene sequence:

>729_bases
ATGTCATCAACAAATATTGAAGTAGTAATGCCCGTTAAGCTGGCTCAGGCATTAGCCAACACATTATTTCCGGCATTAGA
CAGCCAGTTACGTGCTGGCCGTCATATTGGTATTGATGAGTTGGATAATCATGCTTTTTTGATGGATTTTCAGGAGCAAC
TGGAAGAATTTTACGCTCGCTATAATGTCGAGTTAATCCGTGCGCCGGAAGGTTTCTTCTATTTGCGTCCTCGTTCAACC
ACGCTTATTCCGCGCTCAGTTTTATCTGAGTTGGATATGATGGTCGGCAAAATTCTCTGTTATCTCTACCTCAGCCCGGA
ACGGCTGGCTCATGAAGGTATCTTCTCTCAGCAAGAGCTGTACGAAGAGTTACTGAGCCTGGCCGATGAGAGCAAATTGC
TGAAGTTTGTTAACCAGCGCTCGACCGGGTCTGATTTGGATAAACAGAAGTTACAGGAAAAAGTCCGGACGTCACTTAAC
CGGCTGCGTCGGTTGGGCATGATTTATTTTATGGGCAACGACAGCACCAAGTTTCGCATCACTGAAGCGGTATTCCGTTT
TGGTGCGGATGTACGCAGCGGTGATGATCAACGTGAAGCCCAGCTACGCATGATCCGTGATGGCGAAGCCATGGCGGTAG
AAAATAGTCTGTCACTTCATGATGAAAGTGATGATGCTGATGTCACCATGGGCAATGCAGCGGACAGTGTAGAGGATGAA
CAGGAATGA

Upstream 100 bases:

>100_bases
GTCGACCAGGCTGTTCGCCTCGGTGTGGCCGAAGCCGATTTCTCAGGGTTGCCAGCCGAATGGTTAGCAATCAATGATTA
CGGAGCCAAGGTGCAGGCAC

Downstream 100 bases:

>100_bases
TTGAACGCGGTAAATTTCGCTCACTGACCTTAGTTAACTGGAATGGTTTCTTTGCCCGAACATTCGATCTTGATGAGCTG
GTAACAACCCTCTCCGGCGG

Product: condesin subunit E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSSTNIEVVMPVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQEQLEEFYARYNVELIRAPEGFFYLRPRST
TLIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSQQELYEELLSLADESKLLKFVNQRSTGSDLDKQKLQEKVRTSLN
RLRRLGMIYFMGNDSTKFRITEAVFRFGADVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMGNAADSVEDE
QE

Sequences:

>Translated_242_residues
MSSTNIEVVMPVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQEQLEEFYARYNVELIRAPEGFFYLRPRST
TLIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSQQELYEELLSLADESKLLKFVNQRSTGSDLDKQKLQEKVRTSLN
RLRRLGMIYFMGNDSTKFRITEAVFRFGADVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMGNAADSVEDE
QE
>Mature_241_residues
SSTNIEVVMPVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQEQLEEFYARYNVELIRAPEGFFYLRPRSTT
LIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSQQELYEELLSLADESKLLKFVNQRSTGSDLDKQKLQEKVRTSLNR
LRRLGMIYFMGNDSTKFRITEAVFRFGADVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMGNAADSVEDEQ
E

Specific function: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interactio

COG id: COG3095

COG function: function code D; Uncharacterized protein involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm, nucleoid. Note=Restricted to the nucleoid region (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mukE family [H]

Homologues:

Organism=Escherichia coli, GI226510932, Length=240, Percent_Identity=82.0833333333333, Blast_Score=405, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007385 [H]

Pfam domain/function: PF04288 MukE [H]

EC number: NA

Molecular weight: Translated: 27644; Mature: 27512

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTNIEVVMPVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQEQLEEFYAR
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHHHH
YNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSQQEL
CCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHH
YEELLSLADESKLLKFVNQRSTGSDLDKQKLQEKVRTSLNRLRRLGMIYFMGNDSTKFRI
HHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEHH
TEAVFRFGADVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMGNAADSVEDE
HHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCC
QE
CC
>Mature Secondary Structure 
SSTNIEVVMPVKLAQALANTLFPALDSQLRAGRHIGIDELDNHAFLMDFQEQLEEFYAR
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHHHH
YNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYLYLSPERLAHEGIFSQQEL
CCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHH
YEELLSLADESKLLKFVNQRSTGSDLDKQKLQEKVRTSLNRLRRLGMIYFMGNDSTKFRI
HHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEHH
TEAVFRFGADVRSGDDQREAQLRMIRDGEAMAVENSLSLHDESDDADVTMGNAADSVEDE
HHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCC
QE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]