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The map label for this gene is cdd

Identifier: 170024786

GI number: 170024786

Start: 2810384

End: 2811268

Strand: Direct

Name: cdd

Synonym: YPK_2561

Alternate gene names: 170024786

Gene position: 2810384-2811268 (Clockwise)

Preceding gene: 170024785

Following gene: 170024787

Centisome position: 59.93

GC content: 50.17

Gene sequence:

>885_bases
ATGCAAGCACGTTTTCACACCTCTTGGGCTGAGTTACCCGCCTCATTACAATTCGCACTAGAACCTATTCTGAGCGCAGA
AAACTTCCCTGCTATGCTGACCGCTGAGCAAGTGAAAACAGTAAAAAATATCAGTGGCCTGGATGATGATGCCTTGGCTT
TTGCCTTGTTACCGCTAGCAACCGCTTGTGCGCTTACGCCTATATCCCATTTTAATGTGGGTGCCATTGCCCGTGGAAAA
AGTGGTAACTTTTATTTCGGTGCCAATATGGAGTTCCGTGGTGTACCACTGCAACAGACGATCCACGCCGAGCAATGCGC
GGTAACCCATGCCTGGCTGCGTGGTGAAACCAATCTGGTTGCGATCACTGTCAATTACACGCCATGTGGCCATTGCCGCC
AATTTATGAATGAATTGAACAGTGGGTCTGAATTACATATTCATCTACCTGGCCGCCCGCCATCAACACTGGGCCAATAT
TTACCAGACTCTTTTGGACCAACAGATTTAGCGATCACAACACTTTTGATGGACCCCGTGAATCACGGTTACACGCTAGC
AGAAACCGATCCCCTTACGCAGGCAGCGTTAAATGCTGCAAATCATAGCCATGCGCCATACAGCCAATCCCACAGTGGTG
TGGCACTAGAAACCACCAATGGAAAAATTTATGCTGGCCGTTATGCTGAAAATGCCGCCTTTAACCCTAGCCTGCCCCCC
CTGCAAGCCGCGCTAATCTTGGCCAATATCACCGGTGAGAATTGTGCGTCGATCCGCCGCGCTGTACTGGTTGAAGGCCA
TAACGCAGTCACGAGCCAGTGGGATACAACCTTGGCGACATTGAACGCCTTGGGCTGTTCAGCGGTAAAACGCGTGACGT
TTTAA

Upstream 100 bases:

>100_bases
ATTTTAATTACATGAATTTCATAAATAACGAGATATAAATCACAATTACAGGTTTCCAATCTGCCTAGACTAGTCTCCTG
CGACTACTGGAGAGAACCTT

Downstream 100 bases:

>100_bases
TACCATAACAACTTATTGATGGTCGGGGTTAGGCGACTAGCCCCCCTCCCCACAATCAAGCATGGCGATATGAAAACACT
GGAAATCTCTTTCACAGCGA

Product: cytidine deaminase

Products: NA

Alternate protein names: Cytidine aminohydrolase; CDA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MQARFHTSWAELPASLQFALEPILSAENFPAMLTAEQVKTVKNISGLDDDALAFALLPLATACALTPISHFNVGAIARGK
SGNFYFGANMEFRGVPLQQTIHAEQCAVTHAWLRGETNLVAITVNYTPCGHCRQFMNELNSGSELHIHLPGRPPSTLGQY
LPDSFGPTDLAITTLLMDPVNHGYTLAETDPLTQAALNAANHSHAPYSQSHSGVALETTNGKIYAGRYAENAAFNPSLPP
LQAALILANITGENCASIRRAVLVEGHNAVTSQWDTTLATLNALGCSAVKRVTF

Sequences:

>Translated_294_residues
MQARFHTSWAELPASLQFALEPILSAENFPAMLTAEQVKTVKNISGLDDDALAFALLPLATACALTPISHFNVGAIARGK
SGNFYFGANMEFRGVPLQQTIHAEQCAVTHAWLRGETNLVAITVNYTPCGHCRQFMNELNSGSELHIHLPGRPPSTLGQY
LPDSFGPTDLAITTLLMDPVNHGYTLAETDPLTQAALNAANHSHAPYSQSHSGVALETTNGKIYAGRYAENAAFNPSLPP
LQAALILANITGENCASIRRAVLVEGHNAVTSQWDTTLATLNALGCSAVKRVTF
>Mature_294_residues
MQARFHTSWAELPASLQFALEPILSAENFPAMLTAEQVKTVKNISGLDDDALAFALLPLATACALTPISHFNVGAIARGK
SGNFYFGANMEFRGVPLQQTIHAEQCAVTHAWLRGETNLVAITVNYTPCGHCRQFMNELNSGSELHIHLPGRPPSTLGQY
LPDSFGPTDLAITTLLMDPVNHGYTLAETDPLTQAALNAANHSHAPYSQSHSGVALETTNGKIYAGRYAENAAFNPSLPP
LQAALILANITGENCASIRRAVLVEGHNAVTSQWDTTLATLNALGCSAVKRVTF

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family

Homologues:

Organism=Escherichia coli, GI1788465, Length=292, Percent_Identity=65.0684931506849, Blast_Score=352, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDD_YERP3 (A7FJK3)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001401431.1
- ProteinModelPortal:   A7FJK3
- SMR:   A7FJK3
- STRING:   A7FJK3
- GeneID:   5387826
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_2462
- eggNOG:   COG0295
- HOGENOM:   HBG591160
- OMA:   NRSHAPY
- ProtClustDB:   PRK09027
- BioCyc:   YPSE349747:YPSIP31758_2462-MONOMER
- HAMAP:   MF_01558
- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013171
- InterPro:   IPR006263
- InterPro:   IPR016193
- InterPro:   IPR020797
- PIRSF:   PIRSF006334
- TIGRFAMs:   TIGR01355

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF08211 dCMP_cyt_deam_2; SSF53927 Cytidine_deaminase-like

EC number: =3.5.4.5

Molecular weight: Translated: 31477; Mature: 31477

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: ACT_SITE 104-104

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQARFHTSWAELPASLQFALEPILSAENFPAMLTAEQVKTVKNISGLDDDALAFALLPLA
CCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHH
TACALTPISHFNVGAIARGKSGNFYFGANMEFRGVPLQQTIHAEQCAVTHAWLRGETNLV
HHHHHCCCCCCCCCEEEECCCCCEEEECCCEECCCCHHHHHHHHHHHHHHHHHCCCCCEE
AITVNYTPCGHCRQFMNELNSGSELHIHLPGRPPSTLGQYLPDSFGPTDLAITTLLMDPV
EEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCC
NHGYTLAETDPLTQAALNAANHSHAPYSQSHSGVALETTNGKIYAGRYAENAAFNPSLPP
CCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCH
LQAALILANITGENCASIRRAVLVEGHNAVTSQWDTTLATLNALGCSAVKRVTF
HHEEEEEEECCCCHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQARFHTSWAELPASLQFALEPILSAENFPAMLTAEQVKTVKNISGLDDDALAFALLPLA
CCCCCCCHHHHCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHH
TACALTPISHFNVGAIARGKSGNFYFGANMEFRGVPLQQTIHAEQCAVTHAWLRGETNLV
HHHHHCCCCCCCCCEEEECCCCCEEEECCCEECCCCHHHHHHHHHHHHHHHHHCCCCCEE
AITVNYTPCGHCRQFMNELNSGSELHIHLPGRPPSTLGQYLPDSFGPTDLAITTLLMDPV
EEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCC
NHGYTLAETDPLTQAALNAANHSHAPYSQSHSGVALETTNGKIYAGRYAENAAFNPSLPP
CCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCH
LQAALILANITGENCASIRRAVLVEGHNAVTSQWDTTLATLNALGCSAVKRVTF
HHEEEEEEECCCCHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA