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The map label for this gene is putA [H]

Identifier: 170024594

GI number: 170024594

Start: 2603785

End: 2607756

Strand: Direct

Name: putA [H]

Synonym: YPK_2369

Alternate gene names: 170024594

Gene position: 2603785-2607756 (Clockwise)

Preceding gene: 170024588

Following gene: 170024596

Centisome position: 55.52

GC content: 52.74

Gene sequence:

>3972_bases
ATGGCGAGTACCACAATGGGCGTAAAGCTTGATGAAGCAACACGAGACCGCATCAAGAGTGCAGCACAACGTATTGACCG
CACACCACACTGGCTCATTAAACAGGCTATTTTCAACTACTTAGAAAAACTGGAAAGTAACAGTGAATTGCCAGAACTGG
CAACAACAAGTTCACTCTCTCTGCAAGACACAGAAGATGCTATACCGCAACTCACTGAAAACACTCATCAGCCATTCTTG
GATTTTGCGGAACACGTGCTCCCGCAGTCGGTTACCCGTGCCGCCATTACTGCGGCTTATCGTCGCCCAGAAACCGAAGC
GATCCCCATGTTATTGGAACAAGCACGCCTACCCGCAGATTTAGCGCAAGCAACACATAAACTGGCCTATTCCATTGCTG
AAAAACTGCGTAATCAAAAAAGTGCCCATGGCCGCGCGGGCATGGTACAGGGATTGCTGCAAGAGTTCTCACTCTCTTCA
CAGGAAGGCGTGGCATTGATGTGTCTGGCTGAAGCCCTACTACGTATTCCTGACAAGCCAACCCGCGATGCACTGATCCG
CGATAAAATTAGCAACGGCAACTGGCATTCGCATCTGGGACGTAGCCCGTCAATGTTTGTCAATGCAGCCACTTGGGGCC
TGCTATTTACTGGCCGCCTAGTCTCTACCCATAACGAAGCCAAACTCTCCGGCTCACTGAACCGAATTATCGGTAAAGGG
GGTGAGCCGTTGATTCGTAAAGGCGTCGATATGGCGATGCGCTTGATGGGCGAGCAATTCGTCACCGGTGAAACCATTTC
GGAAGCATTGGCAAATGCCCGTAAATTAGAAGATAAAGGGTTCCGCTACTCTTACGATATGCTGGGCGAAGCGGCATTAA
CTGAAGCAGATGCACAGGCTTACCTACTCTCTTACCAACAGGCAATTCATGCCATTGGTAAAGCCTCAAATGGCCGTGGT
ATTTACGAAGGCCCGGGGATTTCAATCAAACTTTCCGCCCTACACCCCCGTTATAGCCGTGCGCAATATGAGCGAGTGAT
GGACGAGTTATACCCGCGTCTGTTATCGCTAACATTACAGGCCCGTCAGTATGATATCGGTATCAATATTGATGCCGAGG
AGGCTGATCGTCTGGAAATCTCTCTCGACCTGTTGGAGAGGCTGTGCTTCGAACCCCAATTGGCAGGTTGGAATGGCATT
GGTTTTGTTATTCAGGCATACCAAAAGCGTTGTCCGTCCACTATTGATGCCGTGATTGATATGGCACAACGTAGCCGCCG
CCGTCTGATGATTCGCCTCGTCAAAGGGGCGTATTGGGACAGCGAAATTAAACGTGCTCAAATTGACGGGTTGGAAGGAT
ACCCGGTTTATACTCGTAAGGTTTATACCGATGTGTCCTATCTGGCCTGCGCCCGCAAATTATTGGCTGTTCCAAACCTG
ATCTATCCGCAATTTGCGACGCATAATGCGCATACTCTGTCAGCGATTTACCACCTTGCCGGGCAAAATTACTACCCCGG
CCAGTATGAGTTCCAATGCCTACACGGCATGGGGGAGCCACTGTATGAGCAAGTGGTCGGGAAAGTTGCCGAGGGTAAGC
TCAACCGCCCATGCCGTATTTATGCTCCGGTCGGTACCCATGAAACATTGCTGGCTTACCTTGTGCGCCGTTTGTTGGAA
AACGGTGCCAACACCTCGTTTGTCAATCGTATCGCTGATGCCACATTACCCCTTGATGAACTGGTTGCGGACCCGGTCAG
TGCGGTAGAAGCCATGGCGGCGGCTGAAGGTCAACTTGGTTTACCTCATCCGCGTATCCCTTTACCACGTGAGCTGTTTG
GTAAAGATCGCGCCAACTCCAGCGGGGTGGATCTTGCCAACGAACACCGCCTTGCGTCGCTCTCCAGCGCGTTGCTGGCC
AGTGCCAGCCAGGTATGGCGTGCGGAGCCCGTCATTGATGCAGAGCAGGACAACGGTGACGCGCTACCGGTTATCAACCC
GGCAGAACCTGCCGATGTGGTTGGCTATGTCCGCGAGGCAACCGAAGGTGAAGTTAGCCGTGCATTGGATGCTGCCGCCC
GTGCTGGCACTATCTGGTTTGCCACCCCCCCGGCTGAACGGGCTGCTATCTTAATCCGCGCCGCTGAGTTGATGGAAAAT
CAGATGCAAACGCTGATGGGAATACTGGTGCGTGAGGCGGGTAAAACCTTCAGTAATGCCATCGCCGAAGTCCGTGAAGC
CGTGGACTTCTTGCATTATTACGCCGGTATAGTCAGGGATAACTTCGCCAATGATAGCCATCGCCCGCTCGGCCCGGTTG
TTTGTATCAGTCCGTGGAACTTCCCACTGGCAATCTTTACCGGTCAGGTTGCCGCCGCGTTAGCAGCAGGCAACAGTGTT
TTGGCAAAACCAGCGGAACAAACACCACTCATTGCCGCACAGGCCGTGCGTATTCTGCTGGACGCAGGCATCCCACAGGG
TGTTCTGCAATTGCTACCTGGCCGCGGTGACAGTGTTGGCGCGCTACTGGTTAATGATGCCCGTGTGCGTGCAGTGATGT
TTACCGGTTCTACCGAAGTAGCCACTATTTTACAACGTAGTATCGCAGGCCGTCTTGATCCACAGGGGCGTCCAACACCG
CTGATCGCGGAAACCGGTGGCCTGAATGCGATGATTGTTGACTCTTCGGCACTGACTGAACAAGTTGTGACCGATGTTGT
CGCCTCTGCCTTTGACAGTGCAGGCCAGCGTTGTTCTGCCCTGCGTATTCTCTGCATTCAGGATGATGTCGCTGAACATA
CGCTGCAAATGTTGCGTGGTGCCATGGCGGAATGCCGGATGGGCAATCCAGAACGCCTGTCTACGGATATTGGTCCCGTT
ATCGACGCCGAAGCGAAAACTGGCATTGAGCGCCATATCCAAGCGATGCGAGCCAAAGGGCGTAAAGTTTATCAGGCAGC
CCGTACCAACAGCTTGGATGAGAAAGAGTGGCAACGTGGAACATTTATCAAACCGACCTTGATTGAATTGGACAGTTTTG
ATGAGCTGCAAAAAGAAGTTTTTGGCCCAGTGCTACATGTTGTACGCTTCCAGCGTCAGCATCTTAATGAGTTAGTCGAT
CAAATTAATGCATCTGGCTATGGCTTAACCTTGGGCATCCACACCCGTATTGATGAAACCATCGCCCGTGTCACTGAAAA
AGCAAAAGTAGGCAATCTCTACGTTAACCGTAATATGGTCGGTGCCGTTGTCGGTGTACAACCTTTTGGTGGCGAGGGGT
TATCAGGTACCGGTCCCAAAGCTGGCGGCCCATTGTATTTGTATCGCCTGCTGAGTAGCCGCCCAGACGACGCACTGGCC
AATACCCTGGCGCATCAGGATGGCGAACAGCAACAAAATGTTGCAGGCCGTGAAGCGCTGCTGACCGCTCACCGCGCGTT
CACTCAATGGGCCACGGAACAACAACATGATTCGCTGGCCACTCTCTGCCAACGCTATGCCTCTCTGGCACAAGGTGGAA
CCGTGCGGTTATTGCCAGGCCCGACCGGTGAGCGCAATACCTATGCCCTGCTGCCTCGTGAGCGAGTCCTTTGTCTTGCC
GATACCGAAAGCGATACTCTTACGCAGTTGGCTGCGGTGTTGGCGACCGGGAGCCAGGTTCTATGGCCGGAGAATGACGT
ACAGAAAGCACTGTTGCCTCAATTGCCTACTGAAGTGCAATCGCGGATCACCCTTACCCACGATTGGCAAACCGCTAACA
TCACCTTCGATGCCGTTATCTATCACGGCGATGCGGATCAACTACGCACGCTATGTGAGCAGGTTGCGCAAATTGATGGC
CCCATTGTCTCTGTACAAGGCTTCGCTCGTGGTGAAACCAATATCCTGCTGGAACGCTTATTAATTGAGCATTCATTGAG
TGTCAATACAGCTGCCGCTGGTGGCAACGCCAGTCTGATGACTATCGGCTAG

Upstream 100 bases:

>100_bases
TCAATCACCGCCAGATTTAACGTGGTTGCACAAAGTTGCAACATGCCTGATATTGTCAGAAATAAAATCATAATTCCCCT
TATCAAAGGAGACGAGCGAC

Downstream 100 bases:

>100_bases
ATTTATTTCTGTCAAAACGAAAGCCACTCCACACTGAACTGACCCCATAAAGTTGGACGGTTTATCAATTAAGGCCCTTC
GGGGCCTTTTGCCAACCAAC

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1323; Mature: 1322

Protein sequence:

>1323_residues
MASTTMGVKLDEATRDRIKSAAQRIDRTPHWLIKQAIFNYLEKLESNSELPELATTSSLSLQDTEDAIPQLTENTHQPFL
DFAEHVLPQSVTRAAITAAYRRPETEAIPMLLEQARLPADLAQATHKLAYSIAEKLRNQKSAHGRAGMVQGLLQEFSLSS
QEGVALMCLAEALLRIPDKPTRDALIRDKISNGNWHSHLGRSPSMFVNAATWGLLFTGRLVSTHNEAKLSGSLNRIIGKG
GEPLIRKGVDMAMRLMGEQFVTGETISEALANARKLEDKGFRYSYDMLGEAALTEADAQAYLLSYQQAIHAIGKASNGRG
IYEGPGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLQARQYDIGINIDAEEADRLEISLDLLERLCFEPQLAGWNGI
GFVIQAYQKRCPSTIDAVIDMAQRSRRRLMIRLVKGAYWDSEIKRAQIDGLEGYPVYTRKVYTDVSYLACARKLLAVPNL
IYPQFATHNAHTLSAIYHLAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVAEGKLNRPCRIYAPVGTHETLLAYLVRRLLE
NGANTSFVNRIADATLPLDELVADPVSAVEAMAAAEGQLGLPHPRIPLPRELFGKDRANSSGVDLANEHRLASLSSALLA
SASQVWRAEPVIDAEQDNGDALPVINPAEPADVVGYVREATEGEVSRALDAAARAGTIWFATPPAERAAILIRAAELMEN
QMQTLMGILVREAGKTFSNAIAEVREAVDFLHYYAGIVRDNFANDSHRPLGPVVCISPWNFPLAIFTGQVAAALAAGNSV
LAKPAEQTPLIAAQAVRILLDAGIPQGVLQLLPGRGDSVGALLVNDARVRAVMFTGSTEVATILQRSIAGRLDPQGRPTP
LIAETGGLNAMIVDSSALTEQVVTDVVASAFDSAGQRCSALRILCIQDDVAEHTLQMLRGAMAECRMGNPERLSTDIGPV
IDAEAKTGIERHIQAMRAKGRKVYQAARTNSLDEKEWQRGTFIKPTLIELDSFDELQKEVFGPVLHVVRFQRQHLNELVD
QINASGYGLTLGIHTRIDETIARVTEKAKVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLSSRPDDALA
NTLAHQDGEQQQNVAGREALLTAHRAFTQWATEQQHDSLATLCQRYASLAQGGTVRLLPGPTGERNTYALLPRERVLCLA
DTESDTLTQLAAVLATGSQVLWPENDVQKALLPQLPTEVQSRITLTHDWQTANITFDAVIYHGDADQLRTLCEQVAQIDG
PIVSVQGFARGETNILLERLLIEHSLSVNTAAAGGNASLMTIG

Sequences:

>Translated_1323_residues
MASTTMGVKLDEATRDRIKSAAQRIDRTPHWLIKQAIFNYLEKLESNSELPELATTSSLSLQDTEDAIPQLTENTHQPFL
DFAEHVLPQSVTRAAITAAYRRPETEAIPMLLEQARLPADLAQATHKLAYSIAEKLRNQKSAHGRAGMVQGLLQEFSLSS
QEGVALMCLAEALLRIPDKPTRDALIRDKISNGNWHSHLGRSPSMFVNAATWGLLFTGRLVSTHNEAKLSGSLNRIIGKG
GEPLIRKGVDMAMRLMGEQFVTGETISEALANARKLEDKGFRYSYDMLGEAALTEADAQAYLLSYQQAIHAIGKASNGRG
IYEGPGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLQARQYDIGINIDAEEADRLEISLDLLERLCFEPQLAGWNGI
GFVIQAYQKRCPSTIDAVIDMAQRSRRRLMIRLVKGAYWDSEIKRAQIDGLEGYPVYTRKVYTDVSYLACARKLLAVPNL
IYPQFATHNAHTLSAIYHLAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVAEGKLNRPCRIYAPVGTHETLLAYLVRRLLE
NGANTSFVNRIADATLPLDELVADPVSAVEAMAAAEGQLGLPHPRIPLPRELFGKDRANSSGVDLANEHRLASLSSALLA
SASQVWRAEPVIDAEQDNGDALPVINPAEPADVVGYVREATEGEVSRALDAAARAGTIWFATPPAERAAILIRAAELMEN
QMQTLMGILVREAGKTFSNAIAEVREAVDFLHYYAGIVRDNFANDSHRPLGPVVCISPWNFPLAIFTGQVAAALAAGNSV
LAKPAEQTPLIAAQAVRILLDAGIPQGVLQLLPGRGDSVGALLVNDARVRAVMFTGSTEVATILQRSIAGRLDPQGRPTP
LIAETGGLNAMIVDSSALTEQVVTDVVASAFDSAGQRCSALRILCIQDDVAEHTLQMLRGAMAECRMGNPERLSTDIGPV
IDAEAKTGIERHIQAMRAKGRKVYQAARTNSLDEKEWQRGTFIKPTLIELDSFDELQKEVFGPVLHVVRFQRQHLNELVD
QINASGYGLTLGIHTRIDETIARVTEKAKVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLSSRPDDALA
NTLAHQDGEQQQNVAGREALLTAHRAFTQWATEQQHDSLATLCQRYASLAQGGTVRLLPGPTGERNTYALLPRERVLCLA
DTESDTLTQLAAVLATGSQVLWPENDVQKALLPQLPTEVQSRITLTHDWQTANITFDAVIYHGDADQLRTLCEQVAQIDG
PIVSVQGFARGETNILLERLLIEHSLSVNTAAAGGNASLMTIG
>Mature_1322_residues
ASTTMGVKLDEATRDRIKSAAQRIDRTPHWLIKQAIFNYLEKLESNSELPELATTSSLSLQDTEDAIPQLTENTHQPFLD
FAEHVLPQSVTRAAITAAYRRPETEAIPMLLEQARLPADLAQATHKLAYSIAEKLRNQKSAHGRAGMVQGLLQEFSLSSQ
EGVALMCLAEALLRIPDKPTRDALIRDKISNGNWHSHLGRSPSMFVNAATWGLLFTGRLVSTHNEAKLSGSLNRIIGKGG
EPLIRKGVDMAMRLMGEQFVTGETISEALANARKLEDKGFRYSYDMLGEAALTEADAQAYLLSYQQAIHAIGKASNGRGI
YEGPGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLQARQYDIGINIDAEEADRLEISLDLLERLCFEPQLAGWNGIG
FVIQAYQKRCPSTIDAVIDMAQRSRRRLMIRLVKGAYWDSEIKRAQIDGLEGYPVYTRKVYTDVSYLACARKLLAVPNLI
YPQFATHNAHTLSAIYHLAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVAEGKLNRPCRIYAPVGTHETLLAYLVRRLLEN
GANTSFVNRIADATLPLDELVADPVSAVEAMAAAEGQLGLPHPRIPLPRELFGKDRANSSGVDLANEHRLASLSSALLAS
ASQVWRAEPVIDAEQDNGDALPVINPAEPADVVGYVREATEGEVSRALDAAARAGTIWFATPPAERAAILIRAAELMENQ
MQTLMGILVREAGKTFSNAIAEVREAVDFLHYYAGIVRDNFANDSHRPLGPVVCISPWNFPLAIFTGQVAAALAAGNSVL
AKPAEQTPLIAAQAVRILLDAGIPQGVLQLLPGRGDSVGALLVNDARVRAVMFTGSTEVATILQRSIAGRLDPQGRPTPL
IAETGGLNAMIVDSSALTEQVVTDVVASAFDSAGQRCSALRILCIQDDVAEHTLQMLRGAMAECRMGNPERLSTDIGPVI
DAEAKTGIERHIQAMRAKGRKVYQAARTNSLDEKEWQRGTFIKPTLIELDSFDELQKEVFGPVLHVVRFQRQHLNELVDQ
INASGYGLTLGIHTRIDETIARVTEKAKVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLSSRPDDALAN
TLAHQDGEQQQNVAGREALLTAHRAFTQWATEQQHDSLATLCQRYASLAQGGTVRLLPGPTGERNTYALLPRERVLCLAD
TESDTLTQLAAVLATGSQVLWPENDVQKALLPQLPTEVQSRITLTHDWQTANITFDAVIYHGDADQLRTLCEQVAQIDGP
IVSVQGFARGETNILLERLLIEHSLSVNTAAAGGNASLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777724, Length=512, Percent_Identity=28.90625, Blast_Score=190, Evalue=1e-47,
Organism=Homo sapiens, GI25777730, Length=458, Percent_Identity=31.2227074235808, Blast_Score=189, Evalue=1e-47,
Organism=Homo sapiens, GI21361176, Length=465, Percent_Identity=29.4623655913978, Blast_Score=184, Evalue=5e-46,
Organism=Homo sapiens, GI153266822, Length=465, Percent_Identity=28.1720430107527, Blast_Score=175, Evalue=3e-43,
Organism=Homo sapiens, GI25777732, Length=459, Percent_Identity=29.6296296296296, Blast_Score=174, Evalue=6e-43,
Organism=Homo sapiens, GI25777736, Length=483, Percent_Identity=28.5714285714286, Blast_Score=170, Evalue=1e-41,
Organism=Homo sapiens, GI25777734, Length=483, Percent_Identity=28.5714285714286, Blast_Score=170, Evalue=1e-41,
Organism=Homo sapiens, GI238859541, Length=483, Percent_Identity=28.5714285714286, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI25777728, Length=415, Percent_Identity=29.3975903614458, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI21614513, Length=423, Percent_Identity=28.8416075650118, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI4507229, Length=491, Percent_Identity=29.938900203666, Blast_Score=159, Evalue=3e-38,
Organism=Homo sapiens, GI238814322, Length=514, Percent_Identity=25.875486381323, Blast_Score=155, Evalue=4e-37,
Organism=Homo sapiens, GI12007648, Length=463, Percent_Identity=28.0777537796976, Blast_Score=154, Evalue=8e-37,
Organism=Homo sapiens, GI25777721, Length=504, Percent_Identity=29.1666666666667, Blast_Score=150, Evalue=1e-35,
Organism=Homo sapiens, GI115387104, Length=450, Percent_Identity=25.7777777777778, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI188035924, Length=505, Percent_Identity=27.1287128712871, Blast_Score=144, Evalue=8e-34,
Organism=Homo sapiens, GI310128103, Length=505, Percent_Identity=27.1287128712871, Blast_Score=143, Evalue=1e-33,
Organism=Homo sapiens, GI310128093, Length=505, Percent_Identity=26.7326732673267, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI25777726, Length=512, Percent_Identity=26.3671875, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI11095441, Length=425, Percent_Identity=25.8823529411765, Blast_Score=137, Evalue=9e-32,
Organism=Homo sapiens, GI310128091, Length=391, Percent_Identity=28.3887468030691, Blast_Score=125, Evalue=4e-28,
Organism=Homo sapiens, GI71773324, Length=369, Percent_Identity=27.9132791327913, Blast_Score=110, Evalue=7e-24,
Organism=Homo sapiens, GI4502043, Length=441, Percent_Identity=28.3446712018141, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI238814371, Length=441, Percent_Identity=28.3446712018141, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI25952152, Length=272, Percent_Identity=30.5147058823529, Blast_Score=103, Evalue=8e-22,
Organism=Homo sapiens, GI206597441, Length=342, Percent_Identity=27.4853801169591, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI206597439, Length=342, Percent_Identity=27.4853801169591, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI22907049, Length=342, Percent_Identity=27.4853801169591, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI310128087, Length=325, Percent_Identity=28.3076923076923, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI73695881, Length=335, Percent_Identity=26.865671641791, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI73695879, Length=335, Percent_Identity=26.865671641791, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI310128089, Length=329, Percent_Identity=27.355623100304, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI4557303, Length=339, Percent_Identity=24.4837758112094, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI73466520, Length=339, Percent_Identity=24.4837758112094, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI310128095, Length=317, Percent_Identity=27.4447949526814, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI310128101, Length=221, Percent_Identity=28.5067873303167, Blast_Score=84, Evalue=1e-15,
Organism=Homo sapiens, GI310128099, Length=221, Percent_Identity=28.5067873303167, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI301500698, Length=465, Percent_Identity=23.4408602150538, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI310128097, Length=264, Percent_Identity=28.030303030303, Blast_Score=81, Evalue=7e-15,
Organism=Homo sapiens, GI223972651, Length=426, Percent_Identity=26.9953051643192, Blast_Score=72, Evalue=5e-12,
Organism=Escherichia coli, GI1787250, Length=1323, Percent_Identity=79.3650793650794, Blast_Score=2137, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=473, Percent_Identity=30.6553911205074, Blast_Score=190, Evalue=5e-49,
Organism=Escherichia coli, GI1787684, Length=479, Percent_Identity=30.2713987473904, Blast_Score=170, Evalue=6e-43,
Organism=Escherichia coli, GI1787715, Length=455, Percent_Identity=31.4285714285714, Blast_Score=169, Evalue=1e-42,
Organism=Escherichia coli, GI1786504, Length=461, Percent_Identity=27.114967462039, Blast_Score=156, Evalue=7e-39,
Organism=Escherichia coli, GI87082295, Length=435, Percent_Identity=29.1954022988506, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1787558, Length=416, Percent_Identity=29.8076923076923, Blast_Score=152, Evalue=2e-37,
Organism=Escherichia coli, GI1788042, Length=448, Percent_Identity=30.1339285714286, Blast_Score=149, Evalue=1e-36,
Organism=Escherichia coli, GI87081896, Length=468, Percent_Identity=27.991452991453, Blast_Score=145, Evalue=2e-35,
Organism=Escherichia coli, GI87081926, Length=453, Percent_Identity=28.0353200883002, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI1787653, Length=392, Percent_Identity=22.7040816326531, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25144435, Length=462, Percent_Identity=29.4372294372294, Blast_Score=175, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17562198, Length=534, Percent_Identity=28.4644194756554, Blast_Score=173, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17534447, Length=462, Percent_Identity=30.3030303030303, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI115534176, Length=437, Percent_Identity=30.8924485125858, Blast_Score=169, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI32564736, Length=412, Percent_Identity=29.3689320388349, Blast_Score=163, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI133930964, Length=467, Percent_Identity=28.2655246252677, Blast_Score=162, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25143874, Length=437, Percent_Identity=27.6887871853547, Blast_Score=160, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI25143876, Length=437, Percent_Identity=27.6887871853547, Blast_Score=160, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI115532534, Length=349, Percent_Identity=31.8051575931232, Blast_Score=154, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71986308, Length=468, Percent_Identity=26.2820512820513, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17534119, Length=465, Percent_Identity=26.8817204301075, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI32564151, Length=425, Percent_Identity=27.2941176470588, Blast_Score=127, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17551164, Length=442, Percent_Identity=25.3393665158371, Blast_Score=126, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71995606, Length=457, Percent_Identity=25.601750547046, Blast_Score=126, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71995613, Length=417, Percent_Identity=24.9400479616307, Blast_Score=119, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17564084, Length=338, Percent_Identity=26.6272189349112, Blast_Score=97, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71990744, Length=305, Percent_Identity=27.8688524590164, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25146391, Length=342, Percent_Identity=25.1461988304094, Blast_Score=96, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25146394, Length=342, Percent_Identity=25.4385964912281, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32566756, Length=342, Percent_Identity=25.1461988304094, Blast_Score=95, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321826, Length=514, Percent_Identity=30.5447470817121, Blast_Score=189, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6325196, Length=468, Percent_Identity=31.4102564102564, Blast_Score=184, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6320917, Length=456, Percent_Identity=31.359649122807, Blast_Score=184, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6324950, Length=454, Percent_Identity=28.6343612334802, Blast_Score=182, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6323821, Length=467, Percent_Identity=28.2655246252677, Blast_Score=158, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6323822, Length=465, Percent_Identity=27.0967741935484, Blast_Score=155, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6319478, Length=482, Percent_Identity=27.1784232365145, Blast_Score=144, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6321828, Length=534, Percent_Identity=22.8464419475655, Blast_Score=111, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6323757, Length=331, Percent_Identity=25.0755287009063, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281362580, Length=454, Percent_Identity=29.295154185022, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI62472918, Length=454, Percent_Identity=29.295154185022, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI62472926, Length=454, Percent_Identity=29.295154185022, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI62472936, Length=454, Percent_Identity=29.295154185022, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI21356737, Length=454, Percent_Identity=29.295154185022, Blast_Score=176, Evalue=1e-43,
Organism=Drosophila melanogaster, GI20129399, Length=467, Percent_Identity=29.1220556745182, Blast_Score=175, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24650465, Length=462, Percent_Identity=26.8398268398268, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24585660, Length=484, Percent_Identity=26.8595041322314, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24668425, Length=452, Percent_Identity=27.8761061946903, Blast_Score=154, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24668417, Length=452, Percent_Identity=27.8761061946903, Blast_Score=154, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24668413, Length=452, Percent_Identity=27.8761061946903, Blast_Score=154, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24666674, Length=451, Percent_Identity=26.8292682926829, Blast_Score=137, Evalue=7e-32,
Organism=Drosophila melanogaster, GI28571806, Length=510, Percent_Identity=25.4901960784314, Blast_Score=136, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571802, Length=510, Percent_Identity=25.4901960784314, Blast_Score=136, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571800, Length=510, Percent_Identity=25.4901960784314, Blast_Score=136, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571798, Length=510, Percent_Identity=25.4901960784314, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571796, Length=510, Percent_Identity=25.4901960784314, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571794, Length=510, Percent_Identity=25.4901960784314, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28574525, Length=463, Percent_Identity=26.3498920086393, Blast_Score=125, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24638878, Length=436, Percent_Identity=25, Blast_Score=111, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24638876, Length=436, Percent_Identity=25, Blast_Score=111, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281360301, Length=431, Percent_Identity=28.0742459396752, Blast_Score=107, Evalue=7e-23,
Organism=Drosophila melanogaster, GI281360299, Length=435, Percent_Identity=28.0459770114943, Blast_Score=107, Evalue=7e-23,
Organism=Drosophila melanogaster, GI281360297, Length=435, Percent_Identity=28.0459770114943, Blast_Score=107, Evalue=7e-23,
Organism=Drosophila melanogaster, GI281360295, Length=435, Percent_Identity=28.0459770114943, Blast_Score=107, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24586250, Length=435, Percent_Identity=28.0459770114943, Blast_Score=107, Evalue=7e-23,
Organism=Drosophila melanogaster, GI281360303, Length=431, Percent_Identity=26.6821345707657, Blast_Score=103, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45552499, Length=435, Percent_Identity=26.6666666666667, Blast_Score=103, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 144385; Mature: 144254

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTTMGVKLDEATRDRIKSAAQRIDRTPHWLIKQAIFNYLEKLESNSELPELATTSSLS
CCCCCCCCEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCC
LQDTEDAIPQLTENTHQPFLDFAEHVLPQSVTRAAITAAYRRPETEAIPMLLEQARLPAD
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHH
LAQATHKLAYSIAEKLRNQKSAHGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCC
TRDALIRDKISNGNWHSHLGRSPSMFVNAATWGLLFTGRLVSTHNEAKLSGSLNRIIGKG
CHHHHHHHHCCCCCCHHHCCCCCCCEEEHHHHHHHHCCHHHCCCCHHHHHCCHHHHHCCC
GEPLIRKGVDMAMRLMGEQFVTGETISEALANARKLEDKGFRYSYDMLGEAALTEADAQA
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHH
YLLSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLQ
HHHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
ARQYDIGINIDAEEADRLEISLDLLERLCFEPQLAGWNGIGFVIQAYQKRCPSTIDAVID
HHEEEEEEECCCCCCCHHEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
MAQRSRRRLMIRLVKGAYWDSEIKRAQIDGLEGYPVYTRKVYTDVSYLACARKLLAVPNL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCH
IYPQFATHNAHTLSAIYHLAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVAEGKLNRPCRI
HCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEE
YAPVGTHETLLAYLVRRLLENGANTSFVNRIADATLPLDELVADPVSAVEAMAAAEGQLG
EECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHCCCCCC
LPHPRIPLPRELFGKDRANSSGVDLANEHRLASLSSALLASASQVWRAEPVIDAEQDNGD
CCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ALPVINPAEPADVVGYVREATEGEVSRALDAAARAGTIWFATPPAERAAILIRAAELMEN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHH
QMQTLMGILVREAGKTFSNAIAEVREAVDFLHYYAGIVRDNFANDSHRPLGPVVCISPWN
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCC
FPLAIFTGQVAAALAAGNSVLAKPAEQTPLIAAQAVRILLDAGIPQGVLQLLPGRGDSVG
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCC
ALLVNDARVRAVMFTGSTEVATILQRSIAGRLDPQGRPTPLIAETGGLNAMIVDSSALTE
EEEEECCEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEECCHHHHH
QVVTDVVASAFDSAGQRCSALRILCIQDDVAEHTLQMLRGAMAECRMGNPERLSTDIGPV
HHHHHHHHHHHHHHCCCHHHEEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
IDAEAKTGIERHIQAMRAKGRKVYQAARTNSLDEKEWQRGTFIKPTLIELDSFDELQKEV
CCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHCCCCCCCHHEECCCHHHHHHHH
FGPVLHVVRFQRQHLNELVDQINASGYGLTLGIHTRIDETIARVTEKAKVGNLYVNRNMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEECCCEE
GAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLSSRPDDALANTLAHQDGEQQQNVAGREAL
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHH
LTAHRAFTQWATEQQHDSLATLCQRYASLAQGGTVRLLPGPTGERNTYALLPRERVLCLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEECCCCCEEEEE
DTESDTLTQLAAVLATGSQVLWPENDVQKALLPQLPTEVQSRITLTHDWQTANITFDAVI
CCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHCCCHHHHHCEEEEECCEEEEEEEEEEE
YHGDADQLRTLCEQVAQIDGPIVSVQGFARGETNILLERLLIEHSLSVNTAAAGGNASLM
EECCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCEEE
TIG
EEC
>Mature Secondary Structure 
ASTTMGVKLDEATRDRIKSAAQRIDRTPHWLIKQAIFNYLEKLESNSELPELATTSSLS
CCCCCCCEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCC
LQDTEDAIPQLTENTHQPFLDFAEHVLPQSVTRAAITAAYRRPETEAIPMLLEQARLPAD
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHH
LAQATHKLAYSIAEKLRNQKSAHGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKP
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCC
TRDALIRDKISNGNWHSHLGRSPSMFVNAATWGLLFTGRLVSTHNEAKLSGSLNRIIGKG
CHHHHHHHHCCCCCCHHHCCCCCCCEEEHHHHHHHHCCHHHCCCCHHHHHCCHHHHHCCC
GEPLIRKGVDMAMRLMGEQFVTGETISEALANARKLEDKGFRYSYDMLGEAALTEADAQA
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHH
YLLSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYERVMDELYPRLLSLTLQ
HHHHHHHHHHHHCCCCCCCCCEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
ARQYDIGINIDAEEADRLEISLDLLERLCFEPQLAGWNGIGFVIQAYQKRCPSTIDAVID
HHEEEEEEECCCCCCCHHEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHH
MAQRSRRRLMIRLVKGAYWDSEIKRAQIDGLEGYPVYTRKVYTDVSYLACARKLLAVPNL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCH
IYPQFATHNAHTLSAIYHLAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVAEGKLNRPCRI
HCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEE
YAPVGTHETLLAYLVRRLLENGANTSFVNRIADATLPLDELVADPVSAVEAMAAAEGQLG
EECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHCCCCCC
LPHPRIPLPRELFGKDRANSSGVDLANEHRLASLSSALLASASQVWRAEPVIDAEQDNGD
CCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
ALPVINPAEPADVVGYVREATEGEVSRALDAAARAGTIWFATPPAERAAILIRAAELMEN
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHH
QMQTLMGILVREAGKTFSNAIAEVREAVDFLHYYAGIVRDNFANDSHRPLGPVVCISPWN
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCC
FPLAIFTGQVAAALAAGNSVLAKPAEQTPLIAAQAVRILLDAGIPQGVLQLLPGRGDSVG
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCC
ALLVNDARVRAVMFTGSTEVATILQRSIAGRLDPQGRPTPLIAETGGLNAMIVDSSALTE
EEEEECCEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCEEEEECCHHHHH
QVVTDVVASAFDSAGQRCSALRILCIQDDVAEHTLQMLRGAMAECRMGNPERLSTDIGPV
HHHHHHHHHHHHHHCCCHHHEEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
IDAEAKTGIERHIQAMRAKGRKVYQAARTNSLDEKEWQRGTFIKPTLIELDSFDELQKEV
CCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHCCCCCCCHHEECCCHHHHHHHH
FGPVLHVVRFQRQHLNELVDQINASGYGLTLGIHTRIDETIARVTEKAKVGNLYVNRNMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEECCCEE
GAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLSSRPDDALANTLAHQDGEQQQNVAGREAL
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHH
LTAHRAFTQWATEQQHDSLATLCQRYASLAQGGTVRLLPGPTGERNTYALLPRERVLCLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEECCCCCEEEEE
DTESDTLTQLAAVLATGSQVLWPENDVQKALLPQLPTEVQSRITLTHDWQTANITFDAVI
CCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHCCCHHHHHCEEEEECCEEEEEEEEEEE
YHGDADQLRTLCEQVAQIDGPIVSVQGFARGETNILLERLLIEHSLSVNTAAAGGNASLM
EECCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCEEE
TIG
EEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]