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The map label for this gene is wrbA [H]

Identifier: 170024588

GI number: 170024588

Start: 2597370

End: 2597969

Strand: Direct

Name: wrbA [H]

Synonym: YPK_2363

Alternate gene names: 170024588

Gene position: 2597370-2597969 (Clockwise)

Preceding gene: 170024586

Following gene: 170024594

Centisome position: 55.39

GC content: 51.33

Gene sequence:

>600_bases
ATGGCGAAAATTTTAGTACTCTATTATTCCATGTATGGGCATATCGAAACACTTGCTGGCGCGATTGCCGAAGGTGCCAG
AAAAGTCAGTGGCGTTGATGTCACCATAAAACGAGTACCTGAAACCATGCCAGCCGAAGCTTTCGCTAAAGCAGGTGGAA
AAACAAACCAACAAGCGCCAGTCGCTACACCACACGAACTGGCCGATTATGATGGCATTATTTTCGGTACACCGACTCGC
TTTGGCAACATGTCCGGGCAGATGCGGACCTTCCTCGACCAGACTGGTGGGTTATGGGCATCGGGTGCACTGTATGGCAA
AGTGGCCAGCGTATTCGCCTCCACCGGGACAGGCGGAGGACAAGAACACACCATCACTTCAACCTGGACCACTCTGGCCC
ATCACGGTTTTATCATTGTTCCAATCGGTTATGGTGCCAAAGAGTTATTTGATGTCTCGCAGACTCGTGGTGGTACACCT
TATGGCGCAACGACAATTGCCGGAGGTGACGGTTCCCGTCAGCCAAGCGCTGAAGAATTGGCGATAGCCCGTTTCCAAGG
TGAACATGTAGCGAAAATTACGGCCAAGCTGAAGGGTTGA

Upstream 100 bases:

>100_bases
CAGCCTGTGCTGATTAGCTTATGGTTAATAGGTGTCATTAGCCGCGACGACTAATGACATCATCAGCCTTATTCAATAAA
TTTGATTGGAGCACCGCGAG

Downstream 100 bases:

>100_bases
TCATAAAGAAATGACAATGAACACGACGCCATAAAAGAATGTAGACGTCATAAAAAGCACCGCGCGATGATGGCGGTGCT
GTATTTTAAGCTTCGAGCAA

Product: TrpR binding protein WrbA

Products: NA

Alternate protein names: Trp repressor-binding protein [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MAKILVLYYSMYGHIETLAGAIAEGARKVSGVDVTIKRVPETMPAEAFAKAGGKTNQQAPVATPHELADYDGIIFGTPTR
FGNMSGQMRTFLDQTGGLWASGALYGKVASVFASTGTGGGQEHTITSTWTTLAHHGFIIVPIGYGAKELFDVSQTRGGTP
YGATTIAGGDGSRQPSAEELAIARFQGEHVAKITAKLKG

Sequences:

>Translated_199_residues
MAKILVLYYSMYGHIETLAGAIAEGARKVSGVDVTIKRVPETMPAEAFAKAGGKTNQQAPVATPHELADYDGIIFGTPTR
FGNMSGQMRTFLDQTGGLWASGALYGKVASVFASTGTGGGQEHTITSTWTTLAHHGFIIVPIGYGAKELFDVSQTRGGTP
YGATTIAGGDGSRQPSAEELAIARFQGEHVAKITAKLKG
>Mature_198_residues
AKILVLYYSMYGHIETLAGAIAEGARKVSGVDVTIKRVPETMPAEAFAKAGGKTNQQAPVATPHELADYDGIIFGTPTRF
GNMSGQMRTFLDQTGGLWASGALYGKVASVFASTGTGGGQEHTITSTWTTLAHHGFIIVPIGYGAKELFDVSQTRGGTPY
GATTIAGGDGSRQPSAEELAIARFQGEHVAKITAKLKG

Specific function: Seems to enhance the formation and/or stability of noncovalent complexes between the trp repressor protein and operator-bearing DNA [H]

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787239, Length=199, Percent_Identity=82.4120603015075, Blast_Score=338, Evalue=1e-94,
Organism=Saccharomyces cerevisiae, GI6320235, Length=199, Percent_Identity=46.2311557788945, Blast_Score=176, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6319849, Length=201, Percent_Identity=45.771144278607, Blast_Score=170, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6319526, Length=202, Percent_Identity=37.6237623762376, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025 [H]

Pfam domain/function: PF03358 FMN_red [H]

EC number: NA

Molecular weight: Translated: 20808; Mature: 20677

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKILVLYYSMYGHIETLAGAIAEGARKVSGVDVTIKRVPETMPAEAFAKAGGKTNQQAP
CCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCC
VATPHELADYDGIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKVASVFASTGTGGG
CCCCHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCCCEECCHHHHHHHHHHHHCCCCCC
QEHTITSTWTTLAHHGFIIVPIGYGAKELFDVSQTRGGTPYGATTIAGGDGSRQPSAEEL
CCCEEHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHH
AIARFQGEHVAKITAKLKG
HHHHHCCCCEEEEEEECCC
>Mature Secondary Structure 
AKILVLYYSMYGHIETLAGAIAEGARKVSGVDVTIKRVPETMPAEAFAKAGGKTNQQAP
CEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCC
VATPHELADYDGIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKVASVFASTGTGGG
CCCCHHHHCCCCEEEECCCCCCCCCCHHHHHHHHCCCCEECCHHHHHHHHHHHHCCCCCC
QEHTITSTWTTLAHHGFIIVPIGYGAKELFDVSQTRGGTPYGATTIAGGDGSRQPSAEEL
CCCEEHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHH
AIARFQGEHVAKITAKLKG
HHHHHCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA