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The map label for this gene is hmsF [H]

Identifier: 170024469

GI number: 170024469

Start: 2484259

End: 2486280

Strand: Reverse

Name: hmsF [H]

Synonym: YPK_2240

Alternate gene names: 170024469

Gene position: 2486280-2484259 (Counterclockwise)

Preceding gene: 170024470

Following gene: 170024468

Centisome position: 53.02

GC content: 47.58

Gene sequence:

>2022_bases
ATGGCGAAGCTATTAATTTTTATCAAATCGCTCATTGTTGGGATGATGATCGTGTCCACTATGGGGTGTGCGGAGAAGCC
AACGTTCGTTCCGCCTGCACAACGTGCATTGCCGCAAAGTGAAAGACCGTGGCAAAAGAATACATTTGTTGTGATTGCTT
ATCATGACGTTGAAGACGATTCAGCCGATCAACGCTATCTGTCGGTAAGAAGCAGCGCATTAAATGAGCAGTTCGTGTGG
TTGCGTGATAACGGTTACCACGTGGTTTCTGTTGATCAAATTTTGGCAGCCCGTAATGGTGGCCCTACATTGCCGGATAA
GGCGGTGCTCCTCACCTTTGACGATGGTTACAGCAGTTTTTATCGGCGCGTTTATCCCTTACTGAAAGCATACAAATGGA
GTGCCGTATTAGCGCCAGTGGGCACTTGGATTGATACCGCCACCGATAAAAAAGTGGATTTCGGTGGCTTGAGCACTGAT
CGGGATCGTTTTGCCACCTGGAAGCAGATTACTGAAATGTCTAAATCAGGGTTGGTTGAAATCGGGGCGCATACTTACGC
TTCTCACTATGGTGTGATTGCTAACCCACAGGGGAATACCGAACCGGCGGCGGCCAATCTGCAATATGATCCCAAAACAA
AACAGTATGAAACTGTTGAAGCCTTTAAGCAGCGAATGGAGAAAGACGTTGCGTTGATAACTCAGCGTATTGTCCAGGCA
ACAGGGAAACAACCACGGGTTTGGGTTTGGCCATACGGTGCGCCGAATGGTACGGTGCTAAATATTTTACGCCAGCATGG
TTATCAACTCGCCATGACCCTAGATCCTGGTGTGGCTAATATTAATGACTTGATGAATATACCGCGCATTTTAATCAGTA
ATAATCCGTCACTGAAGGACTTTGCCCTCACGGTTACCAGCGTGCAAGAAAAAAATATCATGCGGGTGGCGCATGTTGAT
TTGGATTATCTCTACGATCCAGACCCGGCTCAGGAAAAAGAGAATCTTGATAAGTTGGTTCAGCGAATTTCTGACCTACG
TGTCACTCACGTTTTCCTGCAAGCATTTTCTGATCCGAAGGGGGATGGCAACATTCGCCAGGTTTACTTCCCGAACCGTT
GGATCCCGATGCGTCAGGATTTGTTTAACCGGGTGGTATGGCAATTGGCTTCACGGCCTGATGTTGAAGTCTATGCCTGG
ATGCCGGTATTGGCGTTTGATATGGACCCGTCTTTACCTCGTATCACGCGTATTGACCCTAAAACCGGTAAAACGAGTAT
CGACCCAGATCAATATCGCCGTTTGTCACCTTTTAACCCTGAAGTAAGACAGCGCATTATTGATATCTATCGTGATATGG
CCTATAGCGCGCCGATTGACGGAATTATCTATCACGATGATGCGGTGATGTCTGATTTTGAAGATGCTTCCCCCGATGCT
ATCCGGGCCTATGAAAAAGCGGGCTTCCCTGGTTCGATTACCACGATACGCCAAGATCCAGAGATGATGCAGCGGTGGAC
TCGTTACAAGAGTAAGTATCTGATTGATTTTACTAATGAGTTGACCCGCGAAGTCCGTGATATCCGTGGCCCACAGGTAA
AATCGGCGCGTAATATTTTCGCTATGCCTATTTTAGAACCAGAAAGCGAAGCATGGTTTGCACAGAATCTTGATGATTTC
CTCGCTAACTATGATTGGGTCGCACCAATGGCCATGCCGTTAATGGAGAAAGTGCCGCTATCTGAATCTAATGAATGGTT
AGCGGAGCTAGTCAATAAAGTTGCGCAACGCCCCGGTGCTTTGGAGAAAACCGTGTTTGAACTGCAATCTAAGGACTGGA
CCCAACCTGAGGGCAATAACGCCATCAGCGGCCCAATACTGGCGGGATGGATGCGCCAGTTGCAGTTAAGTGGTGCGCAA
AGTTTTGGTTACTACCCGGATAACTTTATTACTGGCGAACCACCGCTAAAAGATGTCCGCCCTGTGCTGTCTTCTGCCTG
GTACCCTTTATATGATCGATAG

Upstream 100 bases:

>100_bases
TGTTGCTGTGGTTTATGACAAGCGTCCTTACGATGGTAAACGTGAGCACGATGTTACGCTTTCTTTCGATTTAAATTATC
GTTTTTAAGGGAATTGGACC

Downstream 100 bases:

>100_bases
AATTATTGCTTTACTCATCCTATGTCTGGTGCTGAGTATCCCTGCGGGAATGATTTTGCTCTTTACCGGCGATGTACTGC
TGAACTTTGTTTTCTTCTAT

Product: outer membrane N-deacetylase

Products: NA

Alternate protein names: PGA N-deacetylase; Poly-beta-1,6-GlcNAc N-deacetylase [H]

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MAKLLIFIKSLIVGMMIVSTMGCAEKPTFVPPAQRALPQSERPWQKNTFVVIAYHDVEDDSADQRYLSVRSSALNEQFVW
LRDNGYHVVSVDQILAARNGGPTLPDKAVLLTFDDGYSSFYRRVYPLLKAYKWSAVLAPVGTWIDTATDKKVDFGGLSTD
RDRFATWKQITEMSKSGLVEIGAHTYASHYGVIANPQGNTEPAAANLQYDPKTKQYETVEAFKQRMEKDVALITQRIVQA
TGKQPRVWVWPYGAPNGTVLNILRQHGYQLAMTLDPGVANINDLMNIPRILISNNPSLKDFALTVTSVQEKNIMRVAHVD
LDYLYDPDPAQEKENLDKLVQRISDLRVTHVFLQAFSDPKGDGNIRQVYFPNRWIPMRQDLFNRVVWQLASRPDVEVYAW
MPVLAFDMDPSLPRITRIDPKTGKTSIDPDQYRRLSPFNPEVRQRIIDIYRDMAYSAPIDGIIYHDDAVMSDFEDASPDA
IRAYEKAGFPGSITTIRQDPEMMQRWTRYKSKYLIDFTNELTREVRDIRGPQVKSARNIFAMPILEPESEAWFAQNLDDF
LANYDWVAPMAMPLMEKVPLSESNEWLAELVNKVAQRPGALEKTVFELQSKDWTQPEGNNAISGPILAGWMRQLQLSGAQ
SFGYYPDNFITGEPPLKDVRPVLSSAWYPLYDR

Sequences:

>Translated_673_residues
MAKLLIFIKSLIVGMMIVSTMGCAEKPTFVPPAQRALPQSERPWQKNTFVVIAYHDVEDDSADQRYLSVRSSALNEQFVW
LRDNGYHVVSVDQILAARNGGPTLPDKAVLLTFDDGYSSFYRRVYPLLKAYKWSAVLAPVGTWIDTATDKKVDFGGLSTD
RDRFATWKQITEMSKSGLVEIGAHTYASHYGVIANPQGNTEPAAANLQYDPKTKQYETVEAFKQRMEKDVALITQRIVQA
TGKQPRVWVWPYGAPNGTVLNILRQHGYQLAMTLDPGVANINDLMNIPRILISNNPSLKDFALTVTSVQEKNIMRVAHVD
LDYLYDPDPAQEKENLDKLVQRISDLRVTHVFLQAFSDPKGDGNIRQVYFPNRWIPMRQDLFNRVVWQLASRPDVEVYAW
MPVLAFDMDPSLPRITRIDPKTGKTSIDPDQYRRLSPFNPEVRQRIIDIYRDMAYSAPIDGIIYHDDAVMSDFEDASPDA
IRAYEKAGFPGSITTIRQDPEMMQRWTRYKSKYLIDFTNELTREVRDIRGPQVKSARNIFAMPILEPESEAWFAQNLDDF
LANYDWVAPMAMPLMEKVPLSESNEWLAELVNKVAQRPGALEKTVFELQSKDWTQPEGNNAISGPILAGWMRQLQLSGAQ
SFGYYPDNFITGEPPLKDVRPVLSSAWYPLYDR
>Mature_672_residues
AKLLIFIKSLIVGMMIVSTMGCAEKPTFVPPAQRALPQSERPWQKNTFVVIAYHDVEDDSADQRYLSVRSSALNEQFVWL
RDNGYHVVSVDQILAARNGGPTLPDKAVLLTFDDGYSSFYRRVYPLLKAYKWSAVLAPVGTWIDTATDKKVDFGGLSTDR
DRFATWKQITEMSKSGLVEIGAHTYASHYGVIANPQGNTEPAAANLQYDPKTKQYETVEAFKQRMEKDVALITQRIVQAT
GKQPRVWVWPYGAPNGTVLNILRQHGYQLAMTLDPGVANINDLMNIPRILISNNPSLKDFALTVTSVQEKNIMRVAHVDL
DYLYDPDPAQEKENLDKLVQRISDLRVTHVFLQAFSDPKGDGNIRQVYFPNRWIPMRQDLFNRVVWQLASRPDVEVYAWM
PVLAFDMDPSLPRITRIDPKTGKTSIDPDQYRRLSPFNPEVRQRIIDIYRDMAYSAPIDGIIYHDDAVMSDFEDASPDAI
RAYEKAGFPGSITTIRQDPEMMQRWTRYKSKYLIDFTNELTREVRDIRGPQVKSARNIFAMPILEPESEAWFAQNLDDFL
ANYDWVAPMAMPLMEKVPLSESNEWLAELVNKVAQRPGALEKTVFELQSKDWTQPEGNNAISGPILAGWMRQLQLSGAQS
FGYYPDNFITGEPPLKDVRPVLSSAWYPLYDR

Specific function: Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl- D-glucosamine (PGA), a biofilm adhesin polysaccharide. N- deacetylation promotes PGA export through the PgaA porin [H]

COG id: COG0726

COG function: function code G; Predicted xylanase/chitin deacetylase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide deacetylase family [H]

Homologues:

Organism=Escherichia coli, GI1787260, Length=662, Percent_Identity=48.6404833836858, Blast_Score=711, Evalue=0.0,
Organism=Escherichia coli, GI1786322, Length=272, Percent_Identity=25.7352941176471, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011330
- InterPro:   IPR002509 [H]

Pfam domain/function: PF01522 Polysacc_deac_1 [H]

EC number: NA

Molecular weight: Translated: 76714; Mature: 76583

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLLIFIKSLIVGMMIVSTMGCAEKPTFVPPAQRALPQSERPWQKNTFVVIAYHDVEDD
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCCCC
SADQRYLSVRSSALNEQFVWLRDNGYHVVSVDQILAARNGGPTLPDKAVLLTFDDGYSSF
CHHHHHHHHHHHHCCCCEEEEECCCEEEEEHHHHHHHCCCCCCCCCCEEEEEECCCHHHH
YRRVYPLLKAYKWSAVLAPVGTWIDTATDKKVDFGGLSTDRDRFATWKQITEMSKSGLVE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
IGAHTYASHYGVIANPQGNTEPAAANLQYDPKTKQYETVEAFKQRMEKDVALITQRIVQA
ECCHHHHHCCCEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TGKQPRVWVWPYGAPNGTVLNILRQHGYQLAMTLDPGVANINDLMNIPRILISNNPSLKD
CCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCEEEECCCCCCCC
FALTVTSVQEKNIMRVAHVDLDYLYDPDPAQEKENLDKLVQRISDLRVTHVFLQAFSDPK
EEEEEEHHHHCCCEEEEECCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDGNIRQVYFPNRWIPMRQDLFNRVVWQLASRPDVEVYAWMPVLAFDMDPSLPRITRIDP
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECEEEEECCCCCCCCEEECCC
KTGKTSIDPDQYRRLSPFNPEVRQRIIDIYRDMAYSAPIDGIIYHDDAVMSDFEDASPDA
CCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHCCCCCCCHH
IRAYEKAGFPGSITTIRQDPEMMQRWTRYKSKYLIDFTNELTREVRDIRGPQVKSARNIF
HHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCEEEEHHHHHHHHHHHCCCCCCCCCCCEE
AMPILEPESEAWFAQNLDDFLANYDWVAPMAMPLMEKVPLSESNEWLAELVNKVAQRPGA
EEEEECCCCCHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCH
LEKTVFELQSKDWTQPEGNNAISGPILAGWMRQLQLSGAQSFGYYPDNFITGEPPLKDVR
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
PVLSSAWYPLYDR
HHHHHCCCCCCCC
>Mature Secondary Structure 
AKLLIFIKSLIVGMMIVSTMGCAEKPTFVPPAQRALPQSERPWQKNTFVVIAYHDVEDD
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCCCC
SADQRYLSVRSSALNEQFVWLRDNGYHVVSVDQILAARNGGPTLPDKAVLLTFDDGYSSF
CHHHHHHHHHHHHCCCCEEEEECCCEEEEEHHHHHHHCCCCCCCCCCEEEEEECCCHHHH
YRRVYPLLKAYKWSAVLAPVGTWIDTATDKKVDFGGLSTDRDRFATWKQITEMSKSGLVE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
IGAHTYASHYGVIANPQGNTEPAAANLQYDPKTKQYETVEAFKQRMEKDVALITQRIVQA
ECCHHHHHCCCEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TGKQPRVWVWPYGAPNGTVLNILRQHGYQLAMTLDPGVANINDLMNIPRILISNNPSLKD
CCCCCEEEEECCCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCEEEECCCCCCCC
FALTVTSVQEKNIMRVAHVDLDYLYDPDPAQEKENLDKLVQRISDLRVTHVFLQAFSDPK
EEEEEEHHHHCCCEEEEECCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDGNIRQVYFPNRWIPMRQDLFNRVVWQLASRPDVEVYAWMPVLAFDMDPSLPRITRIDP
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECEEEEECCCCCCCCEEECCC
KTGKTSIDPDQYRRLSPFNPEVRQRIIDIYRDMAYSAPIDGIIYHDDAVMSDFEDASPDA
CCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHCCCCCCCHH
IRAYEKAGFPGSITTIRQDPEMMQRWTRYKSKYLIDFTNELTREVRDIRGPQVKSARNIF
HHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCEEEEHHHHHHHHHHHCCCCCCCCCCCEE
AMPILEPESEAWFAQNLDDFLANYDWVAPMAMPLMEKVPLSESNEWLAELVNKVAQRPGA
EEEEECCCCCHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCH
LEKTVFELQSKDWTQPEGNNAISGPILAGWMRQLQLSGAQSFGYYPDNFITGEPPLKDVR
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
PVLSSAWYPLYDR
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]