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The map label for this gene is fabH [H]

Identifier: 170024446

GI number: 170024446

Start: 2455494

End: 2456501

Strand: Reverse

Name: fabH [H]

Synonym: YPK_2217

Alternate gene names: 170024446

Gene position: 2456501-2455494 (Counterclockwise)

Preceding gene: 170024448

Following gene: 170024445

Centisome position: 52.38

GC content: 51.19

Gene sequence:

>1008_bases
ATGTCGACATCATTAATTTCAGCACCTCATCTGGCGTTCAAAATTATCGCCACAGGGGTATCGTTACCCCCTGATAGGGT
GGAATCCTCGACGTTGGATCGTAAACTCAATAAGCCTGTCGGTTATGTAGAACAACGTTCTGGTGTCCGGCATCGTTATC
ATGCGACGGCAGATGCTAACCAAGCTGAGTTAGCGGCGGCAGCACTGCATGATGCCCTTGAGCGCCATGGGATCAATCCT
TCCTCAATCGATTTATTAATATCAGCCTCGGCTATTGCCTACCAGGCCCTACCGTGTACGGCGGTGCATATTCTCAAAAT
AGCGGGTCTGGCACCTCGCATTGCTGGGTTTGATATCAATAGCAGTTGCGTGAGCTTTATTTCCGCATTACAGGTGGCTG
CGGGGCTACTGAATGCCGGAACTTATCAGCGTATCGCTATTGTTTCAGCCGATCTGGCATCACGAGGTATTGACTGGAAT
GATGAGGAGTCTTCGCTGATCTTCGGTGATGGTGCCGCATGTGCCATTGTGGAACGAGGAGATGGCCGCAGTAGCATATT
AGCCAGTCTGGTTGAAATGTATCCTACGGGCAGTGAGTTATGTGAGATTCGGGCGGGGGGCACACGATGCAACCCTCGCT
CAGGTATGGATAACGACGATTTCTTATTTCATATGCAGGGCAAGAGGCTGTTCCGACAAGCCTCTGGTATCATTGAAGAT
TATTTCCAGCGGCTATTGGAAAAAAGTGGGCTGACATTAGCGGATATTGCCACGGTAATTCCGCATCAGGCGAGCCATTT
ATCGCTGGCGCATATGCGCAAACGCTTACATGTGCCAACAGATGTGCTGGTGGATATCTATCGAGATCATGGTAACCAGG
TGGCGGCATCGATACCAACTGCATTGCATGCCGCCGTGATGAGCGGGCGCTTTTCGCCGGGTAAACCGGTGATGCTTATT
GGTACCGCAGCAGGGTTGACGCTGGCGGGGATGGTTTTGCTGCCATGA

Upstream 100 bases:

>100_bases
TTTTCGTTCCCCAATAATTAGGGGCAGCCAAAGGGAGATTTCTCCCCAGCCACTCACTGGCACTTCACGTTTCAAGCGCT
AAAAAGGTATCTATCTTTCC

Downstream 100 bases:

>100_bases
GAGCCTTACGATCATGAAAGTCTTAGTGACAGGGGCAACCAGTGGATTGGGGCGCAACGCAGCACAATGGCTGTTGGAGG
CAGGGCACGAGGTTTATGCT

Product: beta-ketoacyl-acyl-carrier-protein synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSTSLISAPHLAFKIIATGVSLPPDRVESSTLDRKLNKPVGYVEQRSGVRHRYHATADANQAELAAAALHDALERHGINP
SSIDLLISASAIAYQALPCTAVHILKIAGLAPRIAGFDINSSCVSFISALQVAAGLLNAGTYQRIAIVSADLASRGIDWN
DEESSLIFGDGAACAIVERGDGRSSILASLVEMYPTGSELCEIRAGGTRCNPRSGMDNDDFLFHMQGKRLFRQASGIIED
YFQRLLEKSGLTLADIATVIPHQASHLSLAHMRKRLHVPTDVLVDIYRDHGNQVAASIPTALHAAVMSGRFSPGKPVMLI
GTAAGLTLAGMVLLP

Sequences:

>Translated_335_residues
MSTSLISAPHLAFKIIATGVSLPPDRVESSTLDRKLNKPVGYVEQRSGVRHRYHATADANQAELAAAALHDALERHGINP
SSIDLLISASAIAYQALPCTAVHILKIAGLAPRIAGFDINSSCVSFISALQVAAGLLNAGTYQRIAIVSADLASRGIDWN
DEESSLIFGDGAACAIVERGDGRSSILASLVEMYPTGSELCEIRAGGTRCNPRSGMDNDDFLFHMQGKRLFRQASGIIED
YFQRLLEKSGLTLADIATVIPHQASHLSLAHMRKRLHVPTDVLVDIYRDHGNQVAASIPTALHAAVMSGRFSPGKPVMLI
GTAAGLTLAGMVLLP
>Mature_334_residues
STSLISAPHLAFKIIATGVSLPPDRVESSTLDRKLNKPVGYVEQRSGVRHRYHATADANQAELAAAALHDALERHGINPS
SIDLLISASAIAYQALPCTAVHILKIAGLAPRIAGFDINSSCVSFISALQVAAGLLNAGTYQRIAIVSADLASRGIDWND
EESSLIFGDGAACAIVERGDGRSSILASLVEMYPTGSELCEIRAGGTRCNPRSGMDNDDFLFHMQGKRLFRQASGIIEDY
FQRLLEKSGLTLADIATVIPHQASHLSLAHMRKRLHVPTDVLVDIYRDHGNQVAASIPTALHAAVMSGRFSPGKPVMLIG
TAAGLTLAGMVLLP

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=314, Percent_Identity=27.7070063694268, Blast_Score=121, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35635; Mature: 35504

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSLISAPHLAFKIIATGVSLPPDRVESSTLDRKLNKPVGYVEQRSGVRHRYHATADAN
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCC
QAELAAAALHDALERHGINPSSIDLLISASAIAYQALPCTAVHILKIAGLAPRIAGFDIN
HHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHCCCCHHCCCCCC
SSCVSFISALQVAAGLLNAGTYQRIAIVSADLASRGIDWNDEESSLIFGDGAACAIVERG
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHCCCCCCCCCCCEEEECCCEEEEEECC
DGRSSILASLVEMYPTGSELCEIRAGGTRCNPRSGMDNDDFLFHMQGKRLFRQASGIIED
CCHHHHHHHHHHHCCCCHHHEEEECCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHH
YFQRLLEKSGLTLADIATVIPHQASHLSLAHMRKRLHVPTDVLVDIYRDHGNQVAASIPT
HHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEHHHHHH
ALHAAVMSGRFSPGKPVMLIGTAAGLTLAGMVLLP
HHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHEECC
>Mature Secondary Structure 
STSLISAPHLAFKIIATGVSLPPDRVESSTLDRKLNKPVGYVEQRSGVRHRYHATADAN
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCC
QAELAAAALHDALERHGINPSSIDLLISASAIAYQALPCTAVHILKIAGLAPRIAGFDIN
HHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHCCCCHHCCCCCC
SSCVSFISALQVAAGLLNAGTYQRIAIVSADLASRGIDWNDEESSLIFGDGAACAIVERG
HHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHCCCCCCCCCCCEEEECCCEEEEEECC
DGRSSILASLVEMYPTGSELCEIRAGGTRCNPRSGMDNDDFLFHMQGKRLFRQASGIIED
CCHHHHHHHHHHHCCCCHHHEEEECCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHH
YFQRLLEKSGLTLADIATVIPHQASHLSLAHMRKRLHVPTDVLVDIYRDHGNQVAASIPT
HHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEHHHHHH
ALHAAVMSGRFSPGKPVMLIGTAAGLTLAGMVLLP
HHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA