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The map label for this gene is cscR [H]

Identifier: 170023965

GI number: 170023965

Start: 1912121

End: 1913167

Strand: Reverse

Name: cscR [H]

Synonym: YPK_1724

Alternate gene names: 170023965

Gene position: 1913167-1912121 (Counterclockwise)

Preceding gene: 170023966

Following gene: 170023963

Centisome position: 40.8

GC content: 49.0

Gene sequence:

>1047_bases
ATGGTCTCACTGAAAGAAGTGGCAAATCTAGCCTCTGTTTCATTAATGACCGCATCTCGAGCGATTAATAGCCCAGAGCA
ACTGCGGCCGGAAACGTATCAGCGAGTGATGCAGGCGATTGAATCCCTGAATTATGTGCCTGATTTTGCAGCCCGTAAGA
TGCGCGGCCACGCCACCAAAACATCAACCCTGGCAGTACTCGCCTGGGATACGGCGACCACACCGTTCTCAGTTGAAATA
TTGCTCTCCATTGAGTTAACTGCCCGAGAGTTTGGCTGGAACAGCTTTTTAGTGAACCTAACCTCACGCGAGGACAGCCA
ACGGGCGCTTAACCAACTACTCGCCCAACGGCCCGATGGCATTATTTTTACCGCTATGGGGCTACGTCAGGTCACCATTC
CCGAGCGATTTCGGGATAAAAACATTGTTCTCGCTAATTGCGTCAGTGAAAGCCATTCAATTCCTAGCTACATTCCCGAT
GATTTTGATGGTCAATATCAAGCCATGAAGTTGCTGCTGCAACGCGGATATCAGCGGCCTTTGTGTCTTTATCTGCCGGA
GTGTACCTTGGCAGGCAAGGCCCGGCGGGCAGGGGTAGAAAAAGCCTGGCAGGAATCTGCATTACCAACAGAGCAACTCA
ATCAGTGCCATATAGCGTGGGGAGATGAACATTATCAGGATGTCATTCCGCTATTGGAACGCCATTGCCCTAAGGGAAAA
CCTAATTTTGATGTGTTAATTTGCGGCGATGACCGTATCGCATTTTTGGCCTATCAGGTTTTACTGGCCAAAGGTGTGGT
AATTCCACAACAGGTTGCGGTGATCGGCTATGGCGATATGGTTGGTATTGGTGAATTGTATCTACCACCACTGACCACAG
TACAACTCCCCTATTATGATATTGGTCGTCAAGCTGCCCTCCATTTAATAAGAGGACGTGAATCGCGGGCAATACATCGG
TTACCCTGCCCACTACTAGAACGGGGATCCATCCGTGACTCAATGCCTAAAACTGTGTGCCTCTTTTCAGTAAACAGCGA
TAAATAG

Upstream 100 bases:

>100_bases
TTGATAGATAATAGTGATATCACTACAACTATAAAATGAGAGCAACAGCATCACCCATGACAATATAATTACCCTGCCAG
CCTAATCCAGGAGGTACGTA

Downstream 100 bases:

>100_bases
CGCTCATGGATGCATGCTAAGGACTGATCACTGCGGAGCAGAGTGGCAAGAACGGGGCTGCGTTATACGGGGAAGCACGC
CATAAATAGTATAAACTTCA

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Csc operon regulatory protein [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATKTSTLAVLAWDTATTPFSVEI
LLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDGIIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPD
DFDGQYQAMKLLLQRGYQRPLCLYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGIGELYLPPLTTVQLPYYDIGRQAALHLIRGRESRAIHR
LPCPLLERGSIRDSMPKTVCLFSVNSDK

Sequences:

>Translated_348_residues
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATKTSTLAVLAWDTATTPFSVEI
LLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDGIIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPD
DFDGQYQAMKLLLQRGYQRPLCLYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGIGELYLPPLTTVQLPYYDIGRQAALHLIRGRESRAIHR
LPCPLLERGSIRDSMPKTVCLFSVNSDK
>Mature_348_residues
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATKTSTLAVLAWDTATTPFSVEI
LLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDGIIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPD
DFDGQYQAMKLLLQRGYQRPLCLYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGIGELYLPPLTTVQLPYYDIGRQAALHLIRGRESRAIHR
LPCPLLERGSIRDSMPKTVCLFSVNSDK

Specific function: Repressor for the csc operon. Binds D-fructose as an inducer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=338, Percent_Identity=26.0355029585799, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790194, Length=334, Percent_Identity=26.6467065868263, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787948, Length=348, Percent_Identity=27.5862068965517, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790715, Length=325, Percent_Identity=25.5384615384615, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1786540, Length=347, Percent_Identity=26.2247838616715, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789068, Length=308, Percent_Identity=28.2467532467532, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789202, Length=306, Percent_Identity=25.8169934640523, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787580, Length=331, Percent_Identity=22.9607250755287, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38998; Mature: 38998

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATK
CCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
TSTLAVLAWDTATTPFSVEILLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDG
CCEEEEEEECCCCCCEEEEEEEEEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCC
IIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPDDFDGQYQAMKLLLQRGYQRP
EEEEECCCEEECCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
LCLYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
EEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHCCCEEEEECCHHHHHHHHHHHHHCCCCC
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGIGELYLPPLTTVQLPYYD
CCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEECCCCCEEECCHHH
IGRQAALHLIRGRESRAIHRLPCPLLERGSIRDSMPKTVCLFSVNSDK
HHHHHHHHHHHCCCCCCHHCCCCCHHCCCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MVSLKEVANLASVSLMTASRAINSPEQLRPETYQRVMQAIESLNYVPDFAARKMRGHATK
CCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
TSTLAVLAWDTATTPFSVEILLSIELTAREFGWNSFLVNLTSREDSQRALNQLLAQRPDG
CCEEEEEEECCCCCCEEEEEEEEEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCC
IIFTAMGLRQVTIPERFRDKNIVLANCVSESHSIPSYIPDDFDGQYQAMKLLLQRGYQRP
EEEEECCCEEECCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
LCLYLPECTLAGKARRAGVEKAWQESALPTEQLNQCHIAWGDEHYQDVIPLLERHCPKGK
EEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHCCCEEEEECCHHHHHHHHHHHHHCCCCC
PNFDVLICGDDRIAFLAYQVLLAKGVVIPQQVAVIGYGDMVGIGELYLPPLTTVQLPYYD
CCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEECCCCCEEECCHHH
IGRQAALHLIRGRESRAIHRLPCPLLERGSIRDSMPKTVCLFSVNSDK
HHHHHHHHHHHCCCCCCHHCCCCCHHCCCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA