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The map label for this gene is yclF [H]

Identifier: 170023905

GI number: 170023905

Start: 1849016

End: 1850554

Strand: Reverse

Name: yclF [H]

Synonym: YPK_1664

Alternate gene names: 170023905

Gene position: 1850554-1849016 (Counterclockwise)

Preceding gene: 170023906

Following gene: 170023901

Centisome position: 39.46

GC content: 51.01

Gene sequence:

>1539_bases
ATGCAAACTTCTGTTAACACTCAAGGCGGCCGCACATTTTTTGGCCACCCTTACCCGCTCAGCGGTCTATTTCTTTCCGA
AATGTGGGAGCGTTTCTCGTTCTACGGTATCCGTCCGTTATTAATTCTATTTATGGCGGCAGCGGTACTTGATGGTGGTA
TGGGCCTCCCCCGCGAGCAAGCCTCGGCTATTGTCGGGATCTTCGCGGGTAGTTTGTATTTAGCCGCATTACCCGGTGGC
TGGTTGGCCGATAACTGGCTAGGGCAGCAACGGGCTGTCTGGTATGGTTCTATTCTGGTTGCGCTGGGCCATCTGTCGAT
TGCGTTATCAGCTTGGTTCGGCAATGACCTGTTCTTTATTGGCCTGGCGTTTATCGTCCTGGGTACTGGCCTGTTTAAGA
CCTGTATCTCCGTCATGGTTGGGACCTTGTATAAGCCGGACGATACACGCCGCGACGGTGGTTTTTCACTGTTCTACATG
GGCATCAATATGGGGTCGTTTATCGCACCGCTGCTTTCTGGCTGGTTGCTAAAGACCCATGGCTGGCACTGGGGTTTTGG
TATCGGCGGAATTGGTATGCTCGTAGCATTGGTGATCTTCCGTTATTTCGCTGTCCCGGCCATGAAACGCTATGATGCCG
AAGTGGGGTTAGATTCAAGCTGGAATAGGCCTACCGTGCAACGTCAGGGCGTTGGCAAGTGGGTGAGTGCCATTATGCTG
TTGCTCGTGATTATAACGGCGCTGATTTCACAAGGGATCATCCCAGTTAACCCTGTGCTGATTGCCAGCGTGTTGGCCTA
TATTATTGCGGCCTCTGTAACCCTTTATTTTGTCTATCTATTTGCCTTTGCCAACATGAACCGCAAAGACCGAGCTCGCT
TGCTGGTTTGCTTTATTCTGTTGGTATCAGCCGCCTTCTTCTGGTCTGCTTTTGAGCAAAAACCCACCTCTTTTAACCTG
TTTGCCAATGACTATACCGACCGTATGGTAATGGGTTTTGAGATCCCGACCGTCTGGTTCCAGTCAATTAACGCCCTGTT
TATTATCTTGCTGGCTCCGGTCTTTAGCTGGGCCTGGCCTGCATTGGCGAAAAAGAAAATTCAGCCAAGCAGTATCACCA
AATTTGTTATTGGTATCTTATGCGCGGCCGCCGGTTTTGGTGTGATGATGCTGGCAGCACAGCATGTACTTAGCAGTGGT
GGTAGCGTTGGTGTTTCGCCACTCTGGTTGGTAATGAGTATCCTGCTGCTGACATTAGGGGAACTGTGCCTTAGCCCTAT
CGGGCTGGCAACCATAACATTATTGGCACCGGATAGAATGCGTGGCCAAGTGATGGGGCTTTGGTTCTGCGCCAGTTCGC
TTGGCAACCTGGCCGCAGGTTTGATTGGTGGCCATGTTAAGGCTGACCAACTTGATATGCTGCCAACCCTGTTTGCCCGT
TGCTCAATTGCGTTGGTCATTTGTGCTGCGATCCTGATATTACTCATCGTGCCAATTCGCCGCATGATGAATAACACGCA
GGGTAAGCAAGCGGCCTGA

Upstream 100 bases:

>100_bases
GTTGGTATTAACGCAATGCCGGAACCAATAAAGAGTAAACAATAAACACTCAGTGGTGGTTTATTCGCCTAATATTACGG
TGATTCTATGGGAAGACTTT

Downstream 100 bases:

>100_bases
TCAGTGATGAGCATTGATTGATTACTAACATTGATCAGTGATTAACGTTGACCAACTATTGGCTCTAATAACGTTTTGTA
ATAGCACAAATACCCGCGTT

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MQTSVNTQGGRTFFGHPYPLSGLFLSEMWERFSFYGIRPLLILFMAAAVLDGGMGLPREQASAIVGIFAGSLYLAALPGG
WLADNWLGQQRAVWYGSILVALGHLSIALSAWFGNDLFFIGLAFIVLGTGLFKTCISVMVGTLYKPDDTRRDGGFSLFYM
GINMGSFIAPLLSGWLLKTHGWHWGFGIGGIGMLVALVIFRYFAVPAMKRYDAEVGLDSSWNRPTVQRQGVGKWVSAIML
LLVIITALISQGIIPVNPVLIASVLAYIIAASVTLYFVYLFAFANMNRKDRARLLVCFILLVSAAFFWSAFEQKPTSFNL
FANDYTDRMVMGFEIPTVWFQSINALFIILLAPVFSWAWPALAKKKIQPSSITKFVIGILCAAAGFGVMMLAAQHVLSSG
GSVGVSPLWLVMSILLLTLGELCLSPIGLATITLLAPDRMRGQVMGLWFCASSLGNLAAGLIGGHVKADQLDMLPTLFAR
CSIALVICAAILILLIVPIRRMMNNTQGKQAA

Sequences:

>Translated_512_residues
MQTSVNTQGGRTFFGHPYPLSGLFLSEMWERFSFYGIRPLLILFMAAAVLDGGMGLPREQASAIVGIFAGSLYLAALPGG
WLADNWLGQQRAVWYGSILVALGHLSIALSAWFGNDLFFIGLAFIVLGTGLFKTCISVMVGTLYKPDDTRRDGGFSLFYM
GINMGSFIAPLLSGWLLKTHGWHWGFGIGGIGMLVALVIFRYFAVPAMKRYDAEVGLDSSWNRPTVQRQGVGKWVSAIML
LLVIITALISQGIIPVNPVLIASVLAYIIAASVTLYFVYLFAFANMNRKDRARLLVCFILLVSAAFFWSAFEQKPTSFNL
FANDYTDRMVMGFEIPTVWFQSINALFIILLAPVFSWAWPALAKKKIQPSSITKFVIGILCAAAGFGVMMLAAQHVLSSG
GSVGVSPLWLVMSILLLTLGELCLSPIGLATITLLAPDRMRGQVMGLWFCASSLGNLAAGLIGGHVKADQLDMLPTLFAR
CSIALVICAAILILLIVPIRRMMNNTQGKQAA
>Mature_512_residues
MQTSVNTQGGRTFFGHPYPLSGLFLSEMWERFSFYGIRPLLILFMAAAVLDGGMGLPREQASAIVGIFAGSLYLAALPGG
WLADNWLGQQRAVWYGSILVALGHLSIALSAWFGNDLFFIGLAFIVLGTGLFKTCISVMVGTLYKPDDTRRDGGFSLFYM
GINMGSFIAPLLSGWLLKTHGWHWGFGIGGIGMLVALVIFRYFAVPAMKRYDAEVGLDSSWNRPTVQRQGVGKWVSAIML
LLVIITALISQGIIPVNPVLIASVLAYIIAASVTLYFVYLFAFANMNRKDRARLLVCFILLVSAAFFWSAFEQKPTSFNL
FANDYTDRMVMGFEIPTVWFQSINALFIILLAPVFSWAWPALAKKKIQPSSITKFVIGILCAAAGFGVMMLAAQHVLSSG
GSVGVSPLWLVMSILLLTLGELCLSPIGLATITLLAPDRMRGQVMGLWFCASSLGNLAAGLIGGHVKADQLDMLPTLFAR
CSIALVICAAILILLIVPIRRMMNNTQGKQAA

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=205, Percent_Identity=32.6829268292683, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4827008, Length=219, Percent_Identity=31.0502283105023, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI226371748, Length=198, Percent_Identity=30.3030303030303, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI1789911, Length=520, Percent_Identity=29.0384615384615, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI1787922, Length=499, Percent_Identity=28.4569138276553, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI1790572, Length=483, Percent_Identity=28.7784679089027, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI1786927, Length=458, Percent_Identity=29.9126637554585, Blast_Score=181, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71987453, Length=411, Percent_Identity=27.007299270073, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17569141, Length=380, Percent_Identity=24.7368421052632, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28571102, Length=205, Percent_Identity=29.7560975609756, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571100, Length=205, Percent_Identity=29.7560975609756, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28571098, Length=205, Percent_Identity=29.7560975609756, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24639585, Length=200, Percent_Identity=31, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24639583, Length=200, Percent_Identity=31, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24639581, Length=200, Percent_Identity=31, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 55686; Mature: 55686

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50850 MFS ; PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]