| Definition | Yersinia pseudotuberculosis YPIII chromosome, complete genome. |
|---|---|
| Accession | NC_010465 |
| Length | 4,689,441 |
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The map label for this gene is tibA [H]
Identifier: 170023638
GI number: 170023638
Start: 1538953
End: 1541232
Strand: Reverse
Name: tibA [H]
Synonym: YPK_1396
Alternate gene names: 170023638
Gene position: 1541232-1538953 (Counterclockwise)
Preceding gene: 170023639
Following gene: 170023635
Centisome position: 32.87
GC content: 44.52
Gene sequence:
>2280_bases TTGAACACCAATAGTAAAAAAACCTACCTTAGCATTGCTATTTCATCCATTCTTTACGCCTCAACAGCAATGAACGCAAA CGCCGATTCATGTACTGATTATACTGTCACTGATATTTGTGAGCAGAGTAAATATGGTGCGGGTGAATTTCATAATATTA AGCTGGGTGATGGTGTCACTGCTGGTAGCGAAGATCACCATTTTGTCTTTAATGGTGAAGGATATGAATTATACAATTCT AACGCGAATTTCTCTGCTCAAATTGCCTCAGGTACCATTCGCTATACCGAAGTGAACAACAGTCACTTTACTGTAAACGC TCACCATTTTCCGGATGATACCATCTATGCCGGCCGTGCAGAAAATACCACATTGAATGATAGCCTGATGTGGGTGGCAA CATCGGCTGATCAGACACTGGCTAAAGGTAATTCAATGGTCGTTGTTTCCACCCAAATGGCCATGGTTGATCAAATTTTT GTTACGACGTTGAATGATGGTAGCCTTCCATTTGATCCCGTCATTACCAATAGCCGCTATGAAGATACGTCATATGAAAT GTTATGGGGTATGAAAAACGAGGCAAAAGGGTGGGATACCAAAGCCACATCGCATGACTCCGTATTTGTTGATGCCAGCA AACAGTCTATCGAAGCCAATGGTCACAGTATTGGTGCCACATTTTATGGTAGGGCCACTCAGGTGGTCAAAGCTGGCGGT GAGTCACAGGATACCCACTTATTTGATCACAGTTATTCCTGGGTATATGCCGAGGCTAAATTAACCGGTCTGACGGAGGT TAATGACGCTGCCACTGTCTATCTGAATGCCGCAGCAACTCAAGGTGCTTACGCTGAGAATGTCGTTCTCAACGGCGAAG ATACAACATTGATGGTGCGCGCGAGTCTGGATAACAATGCCTATGCCACGGTGGATAACCTAATATTGAATGGCGGTGAA GTGGTTTTCCAGCAGAGCTCTGGCGACCAATATGCTTCATTAAACATCGGCACACTTTCCGGCTCGGGCTCCTTCCTATT CAATACCTCTATTGCTGAGGGGAAAGGAAACTTCGTGACTATCGCCAATGCCAGTGGGGAACATAAGGTGATAGTTAACG ACTCTGGCCATGAGATCACCTCACCTGATATGACCACATTGGACTTGATTCACGATCTCAGTGGTGATGCAACATTCACA CTGGCCTCTATTTCTGGAGCTAACATCATTGAAGTCGATGGCGGCACTTACGTATATAGCTTGAATACCTGGGATAATTC CGCACGAGCTGGCGGAAATCTGTGGTATTTAGGCTCAGGTTTGAATACAGGCACTGAGCTTGAACCCGAACCTGAAGAGA AAACAACCCCGTCAACGGATGCGGTGTTGAGTATGGCCTCATCCAACCAGTTTATTTTCGATGGTGAAATGCAAAATCTG CGTTTTCGTAAAGGGGATTTAAATAATAATAAAGGTGATGGCGCCAGTGTTTGGGGGCGTTATTTAACCAACAATACTCG GGTCAATGCTGCTCATGATGCCGCTTACCGTTTGCAGCAAGATGGCTTTGAAATTGGTGCTGATAAAGTGCTGGAAATGT CTTCAGGCCAATTAGTCTTGGGCGGTTTTACCTCTTATAGCAATAACCGAGTGAAACATGCTCGTGGTGGGAACAGTACG GTTGATAGTTATAGCTTGGGTGCCTACGGCACTTATTTCGATAACAGTGGTTATTATGTCGATGCCGTCGTTAAAGCCAA CCGTTTTAAAAACTCACTGAATGCCCATATGACCAACGGCGGTTCGGTACAAAGTGATTATAACCAGAATGCAATCGGTG GCTCACTGGAAGCCGGTTATCACTACAGCCTGTCTAATAATTGGTTCGTAGAGCCTTATGTTCGCACCAGCTATTACACG GCACAGGATAAAGATATTGCGCTGAATAATGGCATGACAGCGAATATTGATAATAACCGCTCAGCTAAAGGTGAAATAGG TACACATCTGGGAACGAAGATTGACCTGAATAATGGGGCTATCATCCGCCCTTATGCCAAAGTCGCTATTGAACGAGAGT TCATCAAATCAAATACCGTGACGATCAATCAGGTTAACGACTTTAATAATGATTTATCAGGACATACCGCGAAGTATGGT TTAGGCATGGATATCAACCTGACGAAACAGACTTCCGTTTATGCCGAAGCCAATTACCGCAACGGGACTCATGTGGAGTC ACCTATCATGGCTAATATCGGTTTCCGGATTAATTTCTAA
Upstream 100 bases:
>100_bases ATTAATTAATCATCATTAATGAGCAATGTAAAATCATAGCGTATCAATGTGGAATACGTAAATTTAATGAAATTAAAAAA TAAATTGGAGTATTGTTACA
Downstream 100 bases:
>100_bases AGAACATACCAGATGAGTGGTTTCCCGCGATAATGCGGGAGACCATTTTTTTGCTCAATAGATTAAACATGTCTACCCAC GTTACTTCGAGCTACATCTT
Product: outer membrane autotransporter
Products: NA
Alternate protein names: Glycoprotein TibA [H]
Number of amino acids: Translated: 759; Mature: 759
Protein sequence:
>759_residues MNTNSKKTYLSIAISSILYASTAMNANADSCTDYTVTDICEQSKYGAGEFHNIKLGDGVTAGSEDHHFVFNGEGYELYNS NANFSAQIASGTIRYTEVNNSHFTVNAHHFPDDTIYAGRAENTTLNDSLMWVATSADQTLAKGNSMVVVSTQMAMVDQIF VTTLNDGSLPFDPVITNSRYEDTSYEMLWGMKNEAKGWDTKATSHDSVFVDASKQSIEANGHSIGATFYGRATQVVKAGG ESQDTHLFDHSYSWVYAEAKLTGLTEVNDAATVYLNAAATQGAYAENVVLNGEDTTLMVRASLDNNAYATVDNLILNGGE VVFQQSSGDQYASLNIGTLSGSGSFLFNTSIAEGKGNFVTIANASGEHKVIVNDSGHEITSPDMTTLDLIHDLSGDATFT LASISGANIIEVDGGTYVYSLNTWDNSARAGGNLWYLGSGLNTGTELEPEPEEKTTPSTDAVLSMASSNQFIFDGEMQNL RFRKGDLNNNKGDGASVWGRYLTNNTRVNAAHDAAYRLQQDGFEIGADKVLEMSSGQLVLGGFTSYSNNRVKHARGGNST VDSYSLGAYGTYFDNSGYYVDAVVKANRFKNSLNAHMTNGGSVQSDYNQNAIGGSLEAGYHYSLSNNWFVEPYVRTSYYT AQDKDIALNNGMTANIDNNRSAKGEIGTHLGTKIDLNNGAIIRPYAKVAIEREFIKSNTVTINQVNDFNNDLSGHTAKYG LGMDINLTKQTSVYAEANYRNGTHVESPIMANIGFRINF
Sequences:
>Translated_759_residues MNTNSKKTYLSIAISSILYASTAMNANADSCTDYTVTDICEQSKYGAGEFHNIKLGDGVTAGSEDHHFVFNGEGYELYNS NANFSAQIASGTIRYTEVNNSHFTVNAHHFPDDTIYAGRAENTTLNDSLMWVATSADQTLAKGNSMVVVSTQMAMVDQIF VTTLNDGSLPFDPVITNSRYEDTSYEMLWGMKNEAKGWDTKATSHDSVFVDASKQSIEANGHSIGATFYGRATQVVKAGG ESQDTHLFDHSYSWVYAEAKLTGLTEVNDAATVYLNAAATQGAYAENVVLNGEDTTLMVRASLDNNAYATVDNLILNGGE VVFQQSSGDQYASLNIGTLSGSGSFLFNTSIAEGKGNFVTIANASGEHKVIVNDSGHEITSPDMTTLDLIHDLSGDATFT LASISGANIIEVDGGTYVYSLNTWDNSARAGGNLWYLGSGLNTGTELEPEPEEKTTPSTDAVLSMASSNQFIFDGEMQNL RFRKGDLNNNKGDGASVWGRYLTNNTRVNAAHDAAYRLQQDGFEIGADKVLEMSSGQLVLGGFTSYSNNRVKHARGGNST VDSYSLGAYGTYFDNSGYYVDAVVKANRFKNSLNAHMTNGGSVQSDYNQNAIGGSLEAGYHYSLSNNWFVEPYVRTSYYT AQDKDIALNNGMTANIDNNRSAKGEIGTHLGTKIDLNNGAIIRPYAKVAIEREFIKSNTVTINQVNDFNNDLSGHTAKYG LGMDINLTKQTSVYAEANYRNGTHVESPIMANIGFRINF >Mature_759_residues MNTNSKKTYLSIAISSILYASTAMNANADSCTDYTVTDICEQSKYGAGEFHNIKLGDGVTAGSEDHHFVFNGEGYELYNS NANFSAQIASGTIRYTEVNNSHFTVNAHHFPDDTIYAGRAENTTLNDSLMWVATSADQTLAKGNSMVVVSTQMAMVDQIF VTTLNDGSLPFDPVITNSRYEDTSYEMLWGMKNEAKGWDTKATSHDSVFVDASKQSIEANGHSIGATFYGRATQVVKAGG ESQDTHLFDHSYSWVYAEAKLTGLTEVNDAATVYLNAAATQGAYAENVVLNGEDTTLMVRASLDNNAYATVDNLILNGGE VVFQQSSGDQYASLNIGTLSGSGSFLFNTSIAEGKGNFVTIANASGEHKVIVNDSGHEITSPDMTTLDLIHDLSGDATFT LASISGANIIEVDGGTYVYSLNTWDNSARAGGNLWYLGSGLNTGTELEPEPEEKTTPSTDAVLSMASSNQFIFDGEMQNL RFRKGDLNNNKGDGASVWGRYLTNNTRVNAAHDAAYRLQQDGFEIGADKVLEMSSGQLVLGGFTSYSNNRVKHARGGNST VDSYSLGAYGTYFDNSGYYVDAVVKANRFKNSLNAHMTNGGSVQSDYNQNAIGGSLEAGYHYSLSNNWFVEPYVRTSYYT AQDKDIALNNGMTANIDNNRSAKGEIGTHLGTKIDLNNGAIIRPYAKVAIEREFIKSNTVTINQVNDFNNDLSGHTAKYG LGMDINLTKQTSVYAEANYRNGTHVESPIMANIGFRINF
Specific function: Mediates both adhesion to and invasion of human intestine epithelial cells. Also mediates bacterial cell aggregation via intercellular TibA-TibA interaction. Enhances biofilm formation [H]
COG id: COG3468
COG function: function code MU; Type V secretory pathway, adhesin AidA
Gene ontology:
Cell location: Adhesin/invasin TibA translocator:Cell outer membrane; Multi-pass membrane protein (Potential). Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 autotransporter (TC 1.B.12) domain [H]
Homologues:
Organism=Escherichia coli, GI87082145, Length=556, Percent_Identity=31.8345323741007, Blast_Score=211, Evalue=2e-55, Organism=Escherichia coli, GI1787452, Length=483, Percent_Identity=25.4658385093168, Blast_Score=85, Evalue=2e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005546 - InterPro: IPR006315 - InterPro: IPR012332 - InterPro: IPR011050 - InterPro: IPR004899 - InterPro: IPR003991 [H]
Pfam domain/function: PF03797 Autotransporter; PF03212 Pertactin [H]
EC number: NA
Molecular weight: Translated: 82122; Mature: 82122
Theoretical pI: Translated: 4.58; Mature: 4.58
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNTNSKKTYLSIAISSILYASTAMNANADSCTDYTVTDICEQSKYGAGEFHNIKLGDGVT CCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCC AGSEDHHFVFNGEGYELYNSNANFSAQIASGTIRYTEVNNSHFTVNAHHFPDDTIYAGRA CCCCCCEEEECCCCEEEECCCCCEEEEEECCEEEEEEECCCEEEEEEEECCCCCEEECCC ENTTLNDSLMWVATSADQTLAKGNSMVVVSTQMAMVDQIFVTTLNDGSLPFDPVITNSRY CCCEECCCEEEEEECCCHHHHCCCCEEEEEEHHHEEEEEEEEEECCCCCCCCCEECCCCC EDTSYEMLWGMKNEAKGWDTKATSHDSVFVDASKQSIEANGHSIGATFYGRATQVVKAGG CCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCEEEEEEECCEEEEEECCC ESQDTHLFDHSYSWVYAEAKLTGLTEVNDAATVYLNAAATQGAYAENVVLNGEDTTLMVR CCCCCEEEECCCEEEEEEEEEECCEECCCCEEEEEECCCCCCCCCCEEEECCCCCEEEEE ASLDNNAYATVDNLILNGGEVVFQQSSGDQYASLNIGTLSGSGSFLFNTSIAEGKGNFVT EECCCCCEEEEEHEEECCCEEEEEECCCCCEEEEEEEEECCCCCEEEEEEEECCCCCEEE IANASGEHKVIVNDSGHEITSPDMTTLDLIHDLSGDATFTLASISGANIIEVDGGTYVYS EECCCCCEEEEECCCCCEECCCCCCHHHHHHHCCCCCEEEEEEECCCCEEEECCCEEEEE LNTWDNSARAGGNLWYLGSGLNTGTELEPEPEEKTTPSTDAVLSMASSNQFIFDGEMQNL EECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHEEEECCCCCEEEECCCCCC RFRKGDLNNNKGDGASVWGRYLTNNTRVNAAHDAAYRLQQDGFEIGADKVLEMSSGQLVL EEECCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCCEEEECCCCEEE GGFTSYSNNRVKHARGGNSTVDSYSLGAYGTYFDNSGYYVDAVVKANRFKNSLNAHMTNG EEEECCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCEEEEEEEECHHHHCCCCEEECCC GSVQSDYNQNAIGGSLEAGYHYSLSNNWFVEPYVRTSYYTAQDKDIALNNGMTANIDNNR CCCCCCCCCCCCCCCCCCCEEEECCCCEEECCEEEEEEEECCCCCEEECCCEEEECCCCC SAKGEIGTHLGTKIDLNNGAIIRPYAKVAIEREFIKSNTVTINQVNDFNNDLSGHTAKYG CCCCCCCCCCCCEEECCCCCEECCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEE LGMDINLTKQTSVYAEANYRNGTHVESPIMANIGFRINF CCEEEEECCCCEEEEEECCCCCCCCCCCEEEECCEEEEC >Mature Secondary Structure MNTNSKKTYLSIAISSILYASTAMNANADSCTDYTVTDICEQSKYGAGEFHNIKLGDGVT CCCCCCEEEEEEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCC AGSEDHHFVFNGEGYELYNSNANFSAQIASGTIRYTEVNNSHFTVNAHHFPDDTIYAGRA CCCCCCEEEECCCCEEEECCCCCEEEEEECCEEEEEEECCCEEEEEEEECCCCCEEECCC ENTTLNDSLMWVATSADQTLAKGNSMVVVSTQMAMVDQIFVTTLNDGSLPFDPVITNSRY CCCEECCCEEEEEECCCHHHHCCCCEEEEEEHHHEEEEEEEEEECCCCCCCCCEECCCCC EDTSYEMLWGMKNEAKGWDTKATSHDSVFVDASKQSIEANGHSIGATFYGRATQVVKAGG CCCCEEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCEEEEEEECCEEEEEECCC ESQDTHLFDHSYSWVYAEAKLTGLTEVNDAATVYLNAAATQGAYAENVVLNGEDTTLMVR CCCCCEEEECCCEEEEEEEEEECCEECCCCEEEEEECCCCCCCCCCEEEECCCCCEEEEE ASLDNNAYATVDNLILNGGEVVFQQSSGDQYASLNIGTLSGSGSFLFNTSIAEGKGNFVT EECCCCCEEEEEHEEECCCEEEEEECCCCCEEEEEEEEECCCCCEEEEEEEECCCCCEEE IANASGEHKVIVNDSGHEITSPDMTTLDLIHDLSGDATFTLASISGANIIEVDGGTYVYS EECCCCCEEEEECCCCCEECCCCCCHHHHHHHCCCCCEEEEEEECCCCEEEECCCEEEEE LNTWDNSARAGGNLWYLGSGLNTGTELEPEPEEKTTPSTDAVLSMASSNQFIFDGEMQNL EECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHEEEECCCCCEEEECCCCCC RFRKGDLNNNKGDGASVWGRYLTNNTRVNAAHDAAYRLQQDGFEIGADKVLEMSSGQLVL EEECCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCCEEEECCCCEEE GGFTSYSNNRVKHARGGNSTVDSYSLGAYGTYFDNSGYYVDAVVKANRFKNSLNAHMTNG EEEECCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCEEEEEEEECHHHHCCCCEEECCC GSVQSDYNQNAIGGSLEAGYHYSLSNNWFVEPYVRTSYYTAQDKDIALNNGMTANIDNNR CCCCCCCCCCCCCCCCCCCEEEECCCCEEECCEEEEEEEECCCCCEEECCCEEEECCCCC SAKGEIGTHLGTKIDLNNGAIIRPYAKVAIEREFIKSNTVTINQVNDFNNDLSGHTAKYG CCCCCCCCCCCCEEECCCCCEECCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEE LGMDINLTKQTSVYAEANYRNGTHVESPIMANIGFRINF CCEEEEECCCCEEEEEECCCCCCCCCCCEEEECCEEEEC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10417177 [H]