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The map label for this gene is nudK

Identifier: 170023632

GI number: 170023632

Start: 1532640

End: 1533236

Strand: Direct

Name: nudK

Synonym: YPK_1390

Alternate gene names: 170023632

Gene position: 1532640-1533236 (Clockwise)

Preceding gene: 170023631

Following gene: 170023633

Centisome position: 32.68

GC content: 47.07

Gene sequence:

>597_bases
ATGTCTGTCAAAATTGAAAATATACAGTGTGAATTGTTATCAAAGAACTGGTTTAAATTACACAAATACACCTTTGATTT
AAAAACAGATGAGGGAACCTCGGTACAACAAATCCGTGAAGTCTATGACCGGGGGAACGGTGCGACTATCTTGTTGTATA
ACCGCCAACAGGGCACGGTGGTGTTGATCGAACAATTCCGGATGCCAACCTATGTTAACGGCAATGCCAGCGGTATGTTG
CTGGAGGCGTGTGCCGGTTTACTGGATAACGATTCGCCAGAGGCGTGTATCCGCCGTGAAGCGATGGAAGAAACGGGTTA
TCAGGTTGATAAAGTACAAAAGCTGTTCGAGGCTTATATGTCGCCGGGGGGTGTGACTGAGCTGGTCTATTTCTTTGCGG
CTGAATATCACCCAGATCAAAAGATAACCGATGAGGTTGGGGTAGAGGACGAGGTCATTGAAGTCGTCGAATTGCCGTTC
CACGATGCTCTCGCGATGGTCGCGGATGGGCGAATTAAAGATGGTAAGACGATTATGTTGTTGCAGTATGCGCAGATTCA
TTTTTTCCCTTCGTCCTTGACGCCACAGCGGTGTTAG

Upstream 100 bases:

>100_bases
GAGTGATGATTAACGCCCTGTGGACTTTGCGTCGGCAGGGCGTTTTTACTGAGGTGTATGCTAGATTACGTTAATGATTA
TCAGGGCCAAAGAAGAGTCT

Downstream 100 bases:

>100_bases
CTGCGCTCACTTACCCGAATCGCCTTTCCCCTGCTTTTATATCTTATTGATCAATAAAACGTCAGTTAATAAAAATGTTA
CGCAGAGTATGGGCTGGTTC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSVKIENIQCELLSKNWFKLHKYTFDLKTDEGTSVQQIREVYDRGNGATILLYNRQQGTVVLIEQFRMPTYVNGNASGML
LEACAGLLDNDSPEACIRREAMEETGYQVDKVQKLFEAYMSPGGVTELVYFFAAEYHPDQKITDEVGVEDEVIEVVELPF
HDALAMVADGRIKDGKTIMLLQYAQIHFFPSSLTPQRC

Sequences:

>Translated_198_residues
MSVKIENIQCELLSKNWFKLHKYTFDLKTDEGTSVQQIREVYDRGNGATILLYNRQQGTVVLIEQFRMPTYVNGNASGML
LEACAGLLDNDSPEACIRREAMEETGYQVDKVQKLFEAYMSPGGVTELVYFFAAEYHPDQKITDEVGVEDEVIEVVELPF
HDALAMVADGRIKDGKTIMLLQYAQIHFFPSSLTPQRC
>Mature_197_residues
SVKIENIQCELLSKNWFKLHKYTFDLKTDEGTSVQQIREVYDRGNGATILLYNRQQGTVVLIEQFRMPTYVNGNASGMLL
EACAGLLDNDSPEACIRREAMEETGYQVDKVQKLFEAYMSPGGVTELVYFFAAEYHPDQKITDEVGVEDEVIEVVELPFH
DALAMVADGRIKDGKTIMLLQYAQIHFFPSSLTPQRC

Specific function: Catalyzes the hydrolysis of GDP-mannose

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1788810, Length=185, Percent_Identity=61.0810810810811, Blast_Score=238, Evalue=2e-64,
Organism=Escherichia coli, GI1789412, Length=190, Percent_Identity=30.5263157894737, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUDK_YERP3 (A7FG78)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400256.1
- ProteinModelPortal:   A7FG78
- SMR:   A7FG78
- STRING:   A7FG78
- GeneID:   5387095
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1276
- eggNOG:   COG0494
- HOGENOM:   HBG692398
- OMA:   WHVLRRT
- ProtClustDB:   CLSK889395
- BioCyc:   YPSE349747:YPSIP31758_1276-MONOMER
- InterPro:   IPR004385
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10
- TIGRFAMs:   TIGR00052

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: NA

Molecular weight: Translated: 22472; Mature: 22341

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKIENIQCELLSKNWFKLHKYTFDLKTDEGTSVQQIREVYDRGNGATILLYNRQQGTV
CCEEECCEEEEEECCCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCE
VLIEQFRMPTYVNGNASGMLLEACAGLLDNDSPEACIRREAMEETGYQVDKVQKLFEAYM
EEEEECCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHC
SPGGVTELVYFFAAEYHPDQKITDEVGVEDEVIEVVELPFHDALAMVADGRIKDGKTIML
CCCCHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEE
LQYAQIHFFPSSLTPQRC
EEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
SVKIENIQCELLSKNWFKLHKYTFDLKTDEGTSVQQIREVYDRGNGATILLYNRQQGTV
CEEECCEEEEEECCCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCE
VLIEQFRMPTYVNGNASGMLLEACAGLLDNDSPEACIRREAMEETGYQVDKVQKLFEAYM
EEEEECCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHC
SPGGVTELVYFFAAEYHPDQKITDEVGVEDEVIEVVELPFHDALAMVADGRIKDGKTIML
CCCCHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEE
LQYAQIHFFPSSLTPQRC
EEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA