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The map label for this gene is acr1 [H]

Identifier: 169629626

GI number: 169629626

Start: 2588315

End: 2589292

Strand: Reverse

Name: acr1 [H]

Synonym: MAB_2540c

Alternate gene names: 169629626

Gene position: 2589292-2588315 (Counterclockwise)

Preceding gene: 169629627

Following gene: 169629625

Centisome position: 51.1

GC content: 62.47

Gene sequence:

>978_bases
ATGTCAACGGTTTTGCCCTCTGGGCCGTCCCCTGTCGTACACCATCCGCTGGCACGCGCCGCGGCGTATCTGATCGGTCC
GCGTGGCCTGCGCGGCACGGAGCGATTACGAAGCGAAGTCGCGGGCAAGATAGTCGTCATCACAGGCGCCTCCTACGGAT
TGGGTGCCGCCACCGCTGAGCTCTTCGCGCAGGCAGGTGCTCAGGTGGTGCTGGCCGCGCGCTCTCTCGAGCAGCTTCGG
CTGGTCGCCGCCGGTATCGCTGAAAAAGGCGGCGAGGCAGCGGTTTACCGACTGGACTTGACCTCCGAGGAATCGATCAC
CGAATTCACGGAGGCGGTTCTGCACGACTTCGGCGAGGTCGACTATCTCATCCACAATGCCGGGAAGTCCTTGCGCCGGT
CGATACACCTTTCCTATGACAGACCCAAAGATGTCAATGCGACGTCCGGCGCCAACTACGTGGGTCCCATGCGGCTCACC
CTGGCACTGCTGCCCGGGATGCGCGCTCGCGGAAGCGGGCACATCGTGAATGTGTCGACAGTCGGCGTGATGTTTGGTGT
GGTGCCCAAGTGGGGCTTTTATCTATCTTCCAAAGCGGCGTTCGATATCTGGATGCGTGCGGTCGGAATGGAAGCTCGCG
GCGACGGCGTCACTCTGACCACGTTCTACGCCGGACTCATGCATACACGGATGAGTGCCCCGAGCCGCTGGATGCGGTTG
CTTCCCGGCCAGACACCACTGGATGCCGCAAAGGTGTTAGCCCGTGCCGTGGTAGACAAGCCGCGAACGCTGACTCCGGC
CTATGGACACCCGTTTGCGATATTGGCTCCGGTGCTGCGCTTTCCGCTGGAACCGATCCTCGGTTTCGTCTATCGCCGGC
TGGGCGATACCCAGGCTTCACTGGCGCGGGTAACGGCCGGACAATCGACCACCACGCGCATTGACGCCCCGGAAAGGATC
GGCGTACATGCCGAATAA

Upstream 100 bases:

>100_bases
TCGAGGCAGTGTTGCCCGACGCCCGGCTGTTGTCTGTGTTCGCCGACCCGGCTTCGCTCATTCCTGTAACCAACAACACC
CAATAGTCGAAAGCACCAAG

Downstream 100 bases:

>100_bases
CCTGCGCGAGAGCCTGCGGCAGTGGGGTGCTGCGATACCTGCTGCCGTTACCTCGGGCGCCTTTACTCCGGTGAGCCCCC
GCGCCCTGGCCTCGCTGGTC

Product: putative Short-chain dehydrogenase/reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSTVLPSGPSPVVHHPLARAAAYLIGPRGLRGTERLRSEVAGKIVVITGASYGLGAATAELFAQAGAQVVLAARSLEQLR
LVAAGIAEKGGEAAVYRLDLTSEESITEFTEAVLHDFGEVDYLIHNAGKSLRRSIHLSYDRPKDVNATSGANYVGPMRLT
LALLPGMRARGSGHIVNVSTVGVMFGVVPKWGFYLSSKAAFDIWMRAVGMEARGDGVTLTTFYAGLMHTRMSAPSRWMRL
LPGQTPLDAAKVLARAVVDKPRTLTPAYGHPFAILAPVLRFPLEPILGFVYRRLGDTQASLARVTAGQSTTTRIDAPERI
GVHAE

Sequences:

>Translated_325_residues
MSTVLPSGPSPVVHHPLARAAAYLIGPRGLRGTERLRSEVAGKIVVITGASYGLGAATAELFAQAGAQVVLAARSLEQLR
LVAAGIAEKGGEAAVYRLDLTSEESITEFTEAVLHDFGEVDYLIHNAGKSLRRSIHLSYDRPKDVNATSGANYVGPMRLT
LALLPGMRARGSGHIVNVSTVGVMFGVVPKWGFYLSSKAAFDIWMRAVGMEARGDGVTLTTFYAGLMHTRMSAPSRWMRL
LPGQTPLDAAKVLARAVVDKPRTLTPAYGHPFAILAPVLRFPLEPILGFVYRRLGDTQASLARVTAGQSTTTRIDAPERI
GVHAE
>Mature_324_residues
STVLPSGPSPVVHHPLARAAAYLIGPRGLRGTERLRSEVAGKIVVITGASYGLGAATAELFAQAGAQVVLAARSLEQLRL
VAAGIAEKGGEAAVYRLDLTSEESITEFTEAVLHDFGEVDYLIHNAGKSLRRSIHLSYDRPKDVNATSGANYVGPMRLTL
ALLPGMRARGSGHIVNVSTVGVMFGVVPKWGFYLSSKAAFDIWMRAVGMEARGDGVTLTTFYAGLMHTRMSAPSRWMRLL
PGQTPLDAAKVLARAVVDKPRTLTPAYGHPFAILAPVLRFPLEPILGFVYRRLGDTQASLARVTAGQSTTTRIDAPERIG
VHAE

Specific function: Catalyzes the NADPH-dependent reduction of long chain acyl-CoA to the corresponding aldehyde [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=289, Percent_Identity=34.6020761245675, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI157739938, Length=263, Percent_Identity=29.277566539924, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI7706318, Length=148, Percent_Identity=35.8108108108108, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI166795268, Length=233, Percent_Identity=30.4721030042918, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI186928839, Length=224, Percent_Identity=30.8035714285714, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI210032110, Length=254, Percent_Identity=27.9527559055118, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI225579078, Length=209, Percent_Identity=27.7511961722488, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI7657478, Length=180, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI226371731, Length=209, Percent_Identity=28.2296650717703, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI142976729, Length=164, Percent_Identity=31.7073170731707, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786701, Length=263, Percent_Identity=28.5171102661597, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787335, Length=193, Percent_Identity=29.0155440414508, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787905, Length=150, Percent_Identity=30, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI2367175, Length=239, Percent_Identity=27.6150627615063, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787820, Length=141, Percent_Identity=31.2056737588652, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=196, Percent_Identity=30.1020408163265, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=196, Percent_Identity=30.1020408163265, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=204, Percent_Identity=33.8235294117647, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=211, Percent_Identity=29.3838862559242, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=202, Percent_Identity=29.2079207920792, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=199, Percent_Identity=31.6582914572864, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=203, Percent_Identity=29.064039408867, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=213, Percent_Identity=28.169014084507, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71997402, Length=297, Percent_Identity=29.2929292929293, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=197, Percent_Identity=29.4416243654822, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=200, Percent_Identity=28.5, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=204, Percent_Identity=29.9019607843137, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=215, Percent_Identity=28.8372093023256, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=217, Percent_Identity=27.1889400921659, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=190, Percent_Identity=27.8947368421053, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=198, Percent_Identity=29.7979797979798, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=250, Percent_Identity=26, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=194, Percent_Identity=28.8659793814433, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=195, Percent_Identity=27.6923076923077, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=251, Percent_Identity=27.4900398406374, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=195, Percent_Identity=28.2051282051282, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=269, Percent_Identity=28.996282527881, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21358495, Length=204, Percent_Identity=35.2941176470588, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24647946, Length=206, Percent_Identity=30.5825242718447, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45553409, Length=201, Percent_Identity=31.3432835820896, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647948, Length=201, Percent_Identity=31.3432835820896, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=194, Percent_Identity=30.9278350515464, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644339, Length=198, Percent_Identity=32.3232323232323, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI23397609, Length=195, Percent_Identity=32.3076923076923, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571526, Length=199, Percent_Identity=29.6482412060301, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24640492, Length=240, Percent_Identity=26.25, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24640442, Length=217, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584752, Length=251, Percent_Identity=27.4900398406374, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34766; Mature: 34634

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVLPSGPSPVVHHPLARAAAYLIGPRGLRGTERLRSEVAGKIVVITGASYGLGAATAE
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHH
LFAQAGAQVVLAARSLEQLRLVAAGIAEKGGEAAVYRLDLTSEESITEFTEAVLHDFGEV
HHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHH
DYLIHNAGKSLRRSIHLSYDRPKDVNATSGANYVGPMRLTLALLPGMRARGSGHIVNVST
HHHHHHHCHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEHHH
VGVMFGVVPKWGFYLSSKAAFDIWMRAVGMEARGDGVTLTTFYAGLMHTRMSAPSRWMRL
HHHHHHHHCCCCCEECCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHH
LPGQTPLDAAKVLARAVVDKPRTLTPAYGHPFAILAPVLRFPLEPILGFVYRRLGDTQAS
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
LARVTAGQSTTTRIDAPERIGVHAE
HHHHHCCCCCCEECCCCHHCCCCCC
>Mature Secondary Structure 
STVLPSGPSPVVHHPLARAAAYLIGPRGLRGTERLRSEVAGKIVVITGASYGLGAATAE
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHH
LFAQAGAQVVLAARSLEQLRLVAAGIAEKGGEAAVYRLDLTSEESITEFTEAVLHDFGEV
HHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCHH
DYLIHNAGKSLRRSIHLSYDRPKDVNATSGANYVGPMRLTLALLPGMRARGSGHIVNVST
HHHHHHHCHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEHHH
VGVMFGVVPKWGFYLSSKAAFDIWMRAVGMEARGDGVTLTTFYAGLMHTRMSAPSRWMRL
HHHHHHHHCCCCCEECCCHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHH
LPGQTPLDAAKVLARAVVDKPRTLTPAYGHPFAILAPVLRFPLEPILGFVYRRLGDTQAS
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHH
LARVTAGQSTTTRIDAPERIGVHAE
HHHHHCCCCCCEECCCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA