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The map label for this gene is eryA [H]

Identifier: 169629343

GI number: 169629343

Start: 2292487

End: 2297532

Strand: Direct

Name: eryA [H]

Synonym: MAB_2257

Alternate gene names: 169629343

Gene position: 2292487-2297532 (Clockwise)

Preceding gene: 169629342

Following gene: 169629344

Centisome position: 45.24

GC content: 64.74

Gene sequence:

>5046_bases
GTGACCGTGGAGATGGATGCACCGACCACCGAGACAGGGCTGGCCGATATTGCCATCGTCGGGATGCAGTGCCGCTTCGC
CGGAGCCGATGACGTCGACAAGTACTGGTCGCTACTTTCGGAAAAACGAGAAGGAGCACGATCTTTGGATGGGCTGGCGG
CGGCGCCCGGGTGGGTGCGCCGCGAGGCCGCTATTGACGGAATCGAACTCTTCGACGCCACATTCTTCGGTTACCCGCCG
GCCGAGGCCGCGATGATCGATCCGCAGCATCGGCTCTTCCTCGAGTGCGCTTACCACGTGTTCGAGCAGGCCGGCTACGA
CCCGGATCGCTACGAGGGACTGGTCGGGGTATACGCGGGCTCCGGACAATCGAGCTACCTCATCGCCAATGTGCTTCCCC
ATCTGGGTGTCAGTCCTTCTTCGGCAGATGCATTGCCGGCCGGATTCGCCAATTCGCCGGGGTCGCTTCCCGGCCGAGTC
TCCTACCATCTGAATCTGACCGGTCCGAGTATTGCGGTCAGCACGGCATGTTCGACGTCGCTCGTGGCGGTACACCTGGC
ATGTCAGGAACTGCTGGACTATCGATGTGACCTGGCTTTGGCCGGTGGAGTGAGCTTGAATCCTCACCCGGGCAAGGGTT
ATCGACACACACCTAACGGGCCGCTCTCTCCTGATGGCCGGTGCCGGGCCTTCGATGCCGCCGCGGCAGGCATGTTTCCA
GGTGACGGCGTGGGAGTTGTGCTGCTCAAGCGTCTGTCCGACGCGCTGGCCGATGGCGACCGAATCCGGGCCGTTGTCAA
GGGAAGCGCGGTCAACAACGACGGACGGCACAAGACCGGGTTCACCGCCCCCAGTGTCACTGCCCAGAGCGAGGTCATCA
TGGCGGCGCACGCGGTTGCCGGGGTAGAGGCGAGTTCGATCGGCATGGTCGAGGCACATGGGACGGGTACGCCGGTGGGC
GATCCCATCGAAGTGGCGGCGCTGACCAAGGCGTTCCGGGAATCCACTGATCGGACTGGCTACTGCATGCTGGGCTCCGC
CAAGACGAATATCGGTCATACCGACACCGCAGCCGGGGTGGCGGGGCTCATCAAGGCCGTGCTGTCCATCGAGCATGGCG
TAATACCCGCGAATCTGCACTACAGCGCCGAGAATCCGCTGCTGGACCTGGCCGGTAGTCCGTTCCGCGTGGCGGCCGAC
ACTGTGGACTGGCCCGAGGGAGACGGACCGCGCCGCGCTGGTGTGAGCGCCTTCGGGATCGGCGGCACCAACGCGCACGT
GGTGCTGGAACAGGCACCGGATCACGTCGAGGCTGAGTCCCCCGGGACCGATGGCGGCCTCGAGTCCTTGCTGGTTTTGT
CGGCCGCCACCCCGTCAGCGCTGGACCAACAAGCCAAGCAACTGGCCGATTATGTCCGTAGCAATAGTGAAGTCGATCCA
GCAGATGTTGCCGACACTCTGCAATGGGGCCGCCGAAAACTGCCCTATCGGCGTTCGGTGGTGTGTGGGTCGGCGAAGCA
GGCGGTGTCGCTGCTGACGGCTCCTGCGCAGGCGACCCGCGCTAGTGACGGAGCGGTACCGCTGGTTTTGTTGTTGCCGG
GAGGCGGGGCGCAGTACGTCGGGATGGGCCGTGGACTTTACGAAACCGAGGAGGTCTTCCGGTCGTCGATCGATCAGTGC
GCTCAGATCCTGGTGCAGCACTGCGATATCGACCTGCGCAGCCATCTATATGGGGACGGGGGGCTCGATGAGCAGCGGCT
CGATGTCGTCTTCCCGGCCGTGGTGGCCACCGAGTACGCACTGGCGACTCAGCTTGCGGCCTGGGGGCTGACACCGAACG
CGATGCTCGGGCACAGCCTCGGCGAATACACAGCGGCATGCCTGTCCGGCGTAATCGATATTGATCAAGTCCTGCCGCTG
GTTTCGGCGCGCGGACGGTTGTTCGCCCGAATGGGTGGTGCCACGACGAGCATCCTGTTGCCGACAGCCGATGTCACGCC
GTTGTTGAGCGGTCGGCTCGTTGTTTCCGGTATCACCGACGCATCCTCGTGCACCGTTTCCGGACCAGCTGCCGAAATTG
GGGCACTGGAACAGGAATTGGAAATACGTGGCGTGCAATTCCAGCGCGTGCGGGTATCGATGGCCGTGCATTCTCCAGAG
TTGGACCCCGTGCTCGGCGAGTTCGCGGATATCTTGGCCGGTGTTACGCTGCGCCCGCCGCGAGTACCGTACCTATCGAA
TGTCACGGGTACCTGGATCCGGCCGGAAGAGGCGATCGATCCGGGTTACTGGATCAGGCACAGCCGTGAGCCGGTGCAAT
TGGCCGCGGGATTCGGTGAGCTGGCCGGCTTACCAGATGCCGTCCTGCTGGAGGTTGGCCCCGGCCAGACTTTGACCAGA
CTTGCCCAGCCGCAAGGTGACGCCTCATTCGCGGCTTTCGCCACGATGCGGCACCGCGACGACCGGCGGAGCGACCGGCG
CGCATTGCTTGCGGCCGTGGGAAAGGCATGGGAGTACGGCGTCGACATCGACTGGAGCCTGTTCTCGGGCGGCCGGCGTC
CGGCACGTGTCGAACTGCCGGGCTATCCCTTCGAGCGGCAGCGATACTGGATCGCCCCGTCCGACGGTATACAGCCGATC
GCCAGTCCAGAGGCGACTGTCCCGGTGTGGCGCAGCACCACACCGGTGATTCCCGCTGCGGAGTTGCCCACGGCGCGTTG
GCTGGTTCTGGTCGGCGAGGGGACGGAGGCTCGTCAGTTCGCCGCCGAGTTCGCCGAAACAATCGGCACCGCTGTCGATC
TGCTGGAGCCGGGGCTGGCACCCGCCTCGGGCGAATACGAGCACGTGGTCTTCCTTGGCGATGCCCACGCAGCGAGGATT
GACCGCGATCGGTACGCGCAATTGGTGGATGCCGTGGATGTCGCGGGTTCAGGGGTGTCGGTGCACGTGTGCCTGTCCAA
CGCCTTCGATGTCACCGGGGCAGAAGAGCTCGATGCCCGCCAATGGCTCGCGTTCGGCGCGGCCCAATGGCTACGGCGTA
GCGCCGAAGCGCGCACCGTGGATGTGGTGGACATGGACCGGCCTGATGTTCGAACGCTGATTGCGGAACTCTCCGTGCCC
GGCGTCAATCGGACGGTCGCCTATCGCAACGGGCGACGCTGGATCCTGGACGGCGAGCCCGTCCAGGGGACCGCGGCAGC
GTGGTCGAACGCCGCTGCAGACTTGCGTGGAGAGTCGATTGAGGTTGGGGCCGTCCAGGGATCGGCATCGGCGTCGAATG
CGCTGGACGACTTGTGCACCCGGCACGTATGTGCGCACTTGCGAAGCGCGGGTGTAGCCCTGACACCAGGAGCCGAGTTC
TCACGCGCCGAGTTGATTGCCCGACTGGGAGTGGTGCCGGACTACCACAAGATGGTGGACGCGTTTATCCGCATTTTGAG
CGAGGACGGAATCGTTGCCAGCGAGAACGGCAGGCTGCGGGTCCTCAAGGAGGCACCTACGGCCGTGCCAGACCTCGGGC
GCTGGTGCGCCGACCATCCCGAGCTGGCGTCATGGGCCCAGCTACTCGACCAATGCGTCGGGGGATATGACGACGTCCTG
CGTGGGCGGATTGCCGGCAATGAGGTCGTCACGCCGGGCGGGGATGACGGTCTGTATCGGACCGTTACCGAACAACGCAT
CGTGCACAGCGATTTCGCTACATACCGCGACTTGATCGGCAGGACGCTCGCCGGGCTGGCCGTGAACGCCTCCCCGGCGC
GACCGCTGCGCGTTCTTGAAATCGGTGCGGGCCGAGGTTATTTGACGTGGCCGGTGATTCATGCGCTGCGCGGCCTGCCG
CCCGGCGCGGTGGAATACCACGTCACCGATATCGGCCGGTCCTTTGTGGTGGCCGCTCAGCAGCAGGCCGAATCGGAGGG
GCTGGATTTCGTACGCTTCGCCGCGCTCGATATTGTCGCGGATCCGGCCGGACAGAGTGTGCCGCTCGATGCGTTCGACG
TCGTCCTGGCGTTCAATGTGTTGCATGTGGCACCGGACCTGACTGGCGCTATTCGCAATACCGCCGCATTCACCGCCCCC
GGCGGCCTGGTGTTCATACTGGAAGCCACGTGTGAAGGGCGCGGCGACTCACTGATCGATCCGCTGTTGACCGGTTGGCT
CGATTTCGACGACGACATGCGGACCGATTCACCGCTGGTGGCGCCGCAGCAGTGGGCGGCGTTGCTTGACGCCAACGGAT
TCGCCGGTTCGACCATCTATGACTCCGGTCCGGCAGGTGACCATGCGCTGATTATCGCCGAACGTCCGGAGCCGGTGCGC
ACTCTGCATCCGGACTTCGATCGGGCGGTCGCCGCGATCGAGGAGATCGCGGCATCGGAACCGTCGGCGCAACGCATGAT
GCTTACCGGGCCGGGCACGGAATCCATCGACGCCGCGATGACCGAGGCGTACGCCCATGGCACCCTCGCGGTCCGATACC
GGGCCGGTGTCGCGGACTGGACCTTTGTCGACAGTTCGGCCTGCGGCGCGAGCGCGGTGACGCCAGACCGATTGGCCGAG
GTACTCACCGCGCCCGCGGTGCCCGCGATAGCACTGTGTGGTCCGACGGCCACAGCGGCACACGAGGGGCAGGAATCGGT
ACCGATGCCGAAGGAATCGGCATCGGCGAACTCGTCATTCAATCAGCGGCCGACACTCGCGACGGAGTACTGCGCACCCC
GTTCGGAACTGGAGGAACGCATCGCCGCCATCTGGAGGCGTTTCTTCGGCTACGACCGCATCGGCGTAAACGACCGCTTC
CTCGAACTCGGTGGTGAGTCGTTACTGGCCATGCAGATTGCCGCCGAACAACGCAATGCGCTAGGGATCGAAGTAAGCAT
GCGGCAATTGCTCGAATCTACAACCGTGGCCGATATCGCCGCAGCCATGACGAATGTGCCGACGAAACAAGACGCTTCAA
CTCCGCCCACACCGCCCGCACGTCGCGGACGTGCCGCGCGGCGTACCGCGGACGGCGTCATACTGCTTGAGGGAGTGCAC
GAGTGA

Upstream 100 bases:

>100_bases
TATCGGTAGCCGAACTCTGGGACCAGGGCGCGACCCTCGCCGATCTTGCCGAATTGGTAGAGCGCCGTGCCATCAACAGC
AAGGTGGGAGAACAACTTAA

Downstream 100 bases:

>100_bases
CAGCCGTCGACTACCGTCCCGCACCTGAGTCGGGTGAGGAGATCATTCTCTTCCGGGCGTCCTTCGCGCAGCAGCGCATG
TGGTTCCTGAGTCGGCTGGA

Product: polyketide synthase

Products: NA

Alternate protein names: 6-deoxyerythronolide B synthase I; DEBS 1; ORF 1 [H]

Number of amino acids: Translated: 1681; Mature: 1680

Protein sequence:

>1681_residues
MTVEMDAPTTETGLADIAIVGMQCRFAGADDVDKYWSLLSEKREGARSLDGLAAAPGWVRREAAIDGIELFDATFFGYPP
AEAAMIDPQHRLFLECAYHVFEQAGYDPDRYEGLVGVYAGSGQSSYLIANVLPHLGVSPSSADALPAGFANSPGSLPGRV
SYHLNLTGPSIAVSTACSTSLVAVHLACQELLDYRCDLALAGGVSLNPHPGKGYRHTPNGPLSPDGRCRAFDAAAAGMFP
GDGVGVVLLKRLSDALADGDRIRAVVKGSAVNNDGRHKTGFTAPSVTAQSEVIMAAHAVAGVEASSIGMVEAHGTGTPVG
DPIEVAALTKAFRESTDRTGYCMLGSAKTNIGHTDTAAGVAGLIKAVLSIEHGVIPANLHYSAENPLLDLAGSPFRVAAD
TVDWPEGDGPRRAGVSAFGIGGTNAHVVLEQAPDHVEAESPGTDGGLESLLVLSAATPSALDQQAKQLADYVRSNSEVDP
ADVADTLQWGRRKLPYRRSVVCGSAKQAVSLLTAPAQATRASDGAVPLVLLLPGGGAQYVGMGRGLYETEEVFRSSIDQC
AQILVQHCDIDLRSHLYGDGGLDEQRLDVVFPAVVATEYALATQLAAWGLTPNAMLGHSLGEYTAACLSGVIDIDQVLPL
VSARGRLFARMGGATTSILLPTADVTPLLSGRLVVSGITDASSCTVSGPAAEIGALEQELEIRGVQFQRVRVSMAVHSPE
LDPVLGEFADILAGVTLRPPRVPYLSNVTGTWIRPEEAIDPGYWIRHSREPVQLAAGFGELAGLPDAVLLEVGPGQTLTR
LAQPQGDASFAAFATMRHRDDRRSDRRALLAAVGKAWEYGVDIDWSLFSGGRRPARVELPGYPFERQRYWIAPSDGIQPI
ASPEATVPVWRSTTPVIPAAELPTARWLVLVGEGTEARQFAAEFAETIGTAVDLLEPGLAPASGEYEHVVFLGDAHAARI
DRDRYAQLVDAVDVAGSGVSVHVCLSNAFDVTGAEELDARQWLAFGAAQWLRRSAEARTVDVVDMDRPDVRTLIAELSVP
GVNRTVAYRNGRRWILDGEPVQGTAAAWSNAAADLRGESIEVGAVQGSASASNALDDLCTRHVCAHLRSAGVALTPGAEF
SRAELIARLGVVPDYHKMVDAFIRILSEDGIVASENGRLRVLKEAPTAVPDLGRWCADHPELASWAQLLDQCVGGYDDVL
RGRIAGNEVVTPGGDDGLYRTVTEQRIVHSDFATYRDLIGRTLAGLAVNASPARPLRVLEIGAGRGYLTWPVIHALRGLP
PGAVEYHVTDIGRSFVVAAQQQAESEGLDFVRFAALDIVADPAGQSVPLDAFDVVLAFNVLHVAPDLTGAIRNTAAFTAP
GGLVFILEATCEGRGDSLIDPLLTGWLDFDDDMRTDSPLVAPQQWAALLDANGFAGSTIYDSGPAGDHALIIAERPEPVR
TLHPDFDRAVAAIEEIAASEPSAQRMMLTGPGTESIDAAMTEAYAHGTLAVRYRAGVADWTFVDSSACGASAVTPDRLAE
VLTAPAVPAIALCGPTATAAHEGQESVPMPKESASANSSFNQRPTLATEYCAPRSELEERIAAIWRRFFGYDRIGVNDRF
LELGGESLLAMQIAAEQRNALGIEVSMRQLLESTTVADIAAAMTNVPTKQDASTPPTPPARRGRAARRTADGVILLEGVH
E

Sequences:

>Translated_1681_residues
MTVEMDAPTTETGLADIAIVGMQCRFAGADDVDKYWSLLSEKREGARSLDGLAAAPGWVRREAAIDGIELFDATFFGYPP
AEAAMIDPQHRLFLECAYHVFEQAGYDPDRYEGLVGVYAGSGQSSYLIANVLPHLGVSPSSADALPAGFANSPGSLPGRV
SYHLNLTGPSIAVSTACSTSLVAVHLACQELLDYRCDLALAGGVSLNPHPGKGYRHTPNGPLSPDGRCRAFDAAAAGMFP
GDGVGVVLLKRLSDALADGDRIRAVVKGSAVNNDGRHKTGFTAPSVTAQSEVIMAAHAVAGVEASSIGMVEAHGTGTPVG
DPIEVAALTKAFRESTDRTGYCMLGSAKTNIGHTDTAAGVAGLIKAVLSIEHGVIPANLHYSAENPLLDLAGSPFRVAAD
TVDWPEGDGPRRAGVSAFGIGGTNAHVVLEQAPDHVEAESPGTDGGLESLLVLSAATPSALDQQAKQLADYVRSNSEVDP
ADVADTLQWGRRKLPYRRSVVCGSAKQAVSLLTAPAQATRASDGAVPLVLLLPGGGAQYVGMGRGLYETEEVFRSSIDQC
AQILVQHCDIDLRSHLYGDGGLDEQRLDVVFPAVVATEYALATQLAAWGLTPNAMLGHSLGEYTAACLSGVIDIDQVLPL
VSARGRLFARMGGATTSILLPTADVTPLLSGRLVVSGITDASSCTVSGPAAEIGALEQELEIRGVQFQRVRVSMAVHSPE
LDPVLGEFADILAGVTLRPPRVPYLSNVTGTWIRPEEAIDPGYWIRHSREPVQLAAGFGELAGLPDAVLLEVGPGQTLTR
LAQPQGDASFAAFATMRHRDDRRSDRRALLAAVGKAWEYGVDIDWSLFSGGRRPARVELPGYPFERQRYWIAPSDGIQPI
ASPEATVPVWRSTTPVIPAAELPTARWLVLVGEGTEARQFAAEFAETIGTAVDLLEPGLAPASGEYEHVVFLGDAHAARI
DRDRYAQLVDAVDVAGSGVSVHVCLSNAFDVTGAEELDARQWLAFGAAQWLRRSAEARTVDVVDMDRPDVRTLIAELSVP
GVNRTVAYRNGRRWILDGEPVQGTAAAWSNAAADLRGESIEVGAVQGSASASNALDDLCTRHVCAHLRSAGVALTPGAEF
SRAELIARLGVVPDYHKMVDAFIRILSEDGIVASENGRLRVLKEAPTAVPDLGRWCADHPELASWAQLLDQCVGGYDDVL
RGRIAGNEVVTPGGDDGLYRTVTEQRIVHSDFATYRDLIGRTLAGLAVNASPARPLRVLEIGAGRGYLTWPVIHALRGLP
PGAVEYHVTDIGRSFVVAAQQQAESEGLDFVRFAALDIVADPAGQSVPLDAFDVVLAFNVLHVAPDLTGAIRNTAAFTAP
GGLVFILEATCEGRGDSLIDPLLTGWLDFDDDMRTDSPLVAPQQWAALLDANGFAGSTIYDSGPAGDHALIIAERPEPVR
TLHPDFDRAVAAIEEIAASEPSAQRMMLTGPGTESIDAAMTEAYAHGTLAVRYRAGVADWTFVDSSACGASAVTPDRLAE
VLTAPAVPAIALCGPTATAAHEGQESVPMPKESASANSSFNQRPTLATEYCAPRSELEERIAAIWRRFFGYDRIGVNDRF
LELGGESLLAMQIAAEQRNALGIEVSMRQLLESTTVADIAAAMTNVPTKQDASTPPTPPARRGRAARRTADGVILLEGVH
E
>Mature_1680_residues
TVEMDAPTTETGLADIAIVGMQCRFAGADDVDKYWSLLSEKREGARSLDGLAAAPGWVRREAAIDGIELFDATFFGYPPA
EAAMIDPQHRLFLECAYHVFEQAGYDPDRYEGLVGVYAGSGQSSYLIANVLPHLGVSPSSADALPAGFANSPGSLPGRVS
YHLNLTGPSIAVSTACSTSLVAVHLACQELLDYRCDLALAGGVSLNPHPGKGYRHTPNGPLSPDGRCRAFDAAAAGMFPG
DGVGVVLLKRLSDALADGDRIRAVVKGSAVNNDGRHKTGFTAPSVTAQSEVIMAAHAVAGVEASSIGMVEAHGTGTPVGD
PIEVAALTKAFRESTDRTGYCMLGSAKTNIGHTDTAAGVAGLIKAVLSIEHGVIPANLHYSAENPLLDLAGSPFRVAADT
VDWPEGDGPRRAGVSAFGIGGTNAHVVLEQAPDHVEAESPGTDGGLESLLVLSAATPSALDQQAKQLADYVRSNSEVDPA
DVADTLQWGRRKLPYRRSVVCGSAKQAVSLLTAPAQATRASDGAVPLVLLLPGGGAQYVGMGRGLYETEEVFRSSIDQCA
QILVQHCDIDLRSHLYGDGGLDEQRLDVVFPAVVATEYALATQLAAWGLTPNAMLGHSLGEYTAACLSGVIDIDQVLPLV
SARGRLFARMGGATTSILLPTADVTPLLSGRLVVSGITDASSCTVSGPAAEIGALEQELEIRGVQFQRVRVSMAVHSPEL
DPVLGEFADILAGVTLRPPRVPYLSNVTGTWIRPEEAIDPGYWIRHSREPVQLAAGFGELAGLPDAVLLEVGPGQTLTRL
AQPQGDASFAAFATMRHRDDRRSDRRALLAAVGKAWEYGVDIDWSLFSGGRRPARVELPGYPFERQRYWIAPSDGIQPIA
SPEATVPVWRSTTPVIPAAELPTARWLVLVGEGTEARQFAAEFAETIGTAVDLLEPGLAPASGEYEHVVFLGDAHAARID
RDRYAQLVDAVDVAGSGVSVHVCLSNAFDVTGAEELDARQWLAFGAAQWLRRSAEARTVDVVDMDRPDVRTLIAELSVPG
VNRTVAYRNGRRWILDGEPVQGTAAAWSNAAADLRGESIEVGAVQGSASASNALDDLCTRHVCAHLRSAGVALTPGAEFS
RAELIARLGVVPDYHKMVDAFIRILSEDGIVASENGRLRVLKEAPTAVPDLGRWCADHPELASWAQLLDQCVGGYDDVLR
GRIAGNEVVTPGGDDGLYRTVTEQRIVHSDFATYRDLIGRTLAGLAVNASPARPLRVLEIGAGRGYLTWPVIHALRGLPP
GAVEYHVTDIGRSFVVAAQQQAESEGLDFVRFAALDIVADPAGQSVPLDAFDVVLAFNVLHVAPDLTGAIRNTAAFTAPG
GLVFILEATCEGRGDSLIDPLLTGWLDFDDDMRTDSPLVAPQQWAALLDANGFAGSTIYDSGPAGDHALIIAERPEPVRT
LHPDFDRAVAAIEEIAASEPSAQRMMLTGPGTESIDAAMTEAYAHGTLAVRYRAGVADWTFVDSSACGASAVTPDRLAEV
LTAPAVPAIALCGPTATAAHEGQESVPMPKESASANSSFNQRPTLATEYCAPRSELEERIAAIWRRFFGYDRIGVNDRFL
ELGGESLLAMQIAAEQRNALGIEVSMRQLLESTTVADIAAAMTNVPTKQDASTPPTPPARRGRAARRTADGVILLEGVHE

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=859, Percent_Identity=28.8707799767171, Blast_Score=267, Evalue=7e-71,
Organism=Homo sapiens, GI8923559, Length=279, Percent_Identity=29.3906810035842, Blast_Score=86, Evalue=3e-16,
Organism=Escherichia coli, GI1787337, Length=289, Percent_Identity=28.719723183391, Blast_Score=88, Evalue=4e-18,
Organism=Escherichia coli, GI1788663, Length=385, Percent_Identity=26.2337662337662, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17550940, Length=862, Percent_Identity=26.1020881670534, Blast_Score=271, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI212642053, Length=916, Percent_Identity=26.7467248908297, Blast_Score=263, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI71983541, Length=302, Percent_Identity=30.1324503311258, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71983535, Length=269, Percent_Identity=31.2267657992565, Blast_Score=94, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6320904, Length=275, Percent_Identity=26.5454545454545, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581345, Length=819, Percent_Identity=28.5714285714286, Blast_Score=256, Evalue=8e-68,
Organism=Drosophila melanogaster, GI221330659, Length=796, Percent_Identity=29.2713567839196, Blast_Score=249, Evalue=9e-66,
Organism=Drosophila melanogaster, GI19920632, Length=796, Percent_Identity=29.2713567839196, Blast_Score=249, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24644341, Length=285, Percent_Identity=28.4210526315789, Blast_Score=79, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR013968
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.94 [H]

Molecular weight: Translated: 177738; Mature: 177606

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50075 ACP_DOMAIN ; PS00098 THIOLASE_1 ; PS00606 B_KETOACYL_SYNTHASE ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVEMDAPTTETGLADIAIVGMQCRFAGADDVDKYWSLLSEKREGARSLDGLAAAPGWVR
CEEECCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
REAAIDGIELFDATFFGYPPAEAAMIDPQHRLFLECAYHVFEQAGYDPDRYEGLVGVYAG
HHHHCCCHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEC
SGQSSYLIANVLPHLGVSPSSADALPAGFANSPGSLPGRVSYHLNLTGPSIAVSTACSTS
CCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEHHHHHH
LVAVHLACQELLDYRCDLALAGGVSLNPHPGKGYRHTPNGPLSPDGRCRAFDAAAAGMFP
HHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCC
GDGVGVVLLKRLSDALADGDRIRAVVKGSAVNNDGRHKTGFTAPSVTAQSEVIMAAHAVA
CCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GVEASSIGMVEAHGTGTPVGDPIEVAALTKAFRESTDRTGYCMLGSAKTNIGHTDTAAGV
CCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHH
AGLIKAVLSIEHGVIPANLHYSAENPLLDLAGSPFRVAADTVDWPEGDGPRRAGVSAFGI
HHHHHHHHHHHCCCEECEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEC
GGTNAHVVLEQAPDHVEAESPGTDGGLESLLVLSAATPSALDQQAKQLADYVRSNSEVDP
CCCCEEEEEECCCCCCCCCCCCCCCCHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCH
ADVADTLQWGRRKLPYRRSVVCGSAKQAVSLLTAPAQATRASDGAVPLVLLLPGGGAQYV
HHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHCCHHHHCCCCCCCEEEEEECCCCCEEE
GMGRGLYETEEVFRSSIDQCAQILVQHCDIDLRSHLYGDGGLDEQRLDVVFPAVVATEYA
ECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LATQLAAWGLTPNAMLGHSLGEYTAACLSGVIDIDQVLPLVSARGRLFARMGGATTSILL
HHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHCCCEEECCCCCCEEEEE
PTADVTPLLSGRLVVSGITDASSCTVSGPAAEIGALEQELEIRGVQFQRVRVSMAVHSPE
ECCCCCHHHCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCC
LDPVLGEFADILAGVTLRPPRVPYLSNVTGTWIRPEEAIDPGYWIRHSREPVQLAAGFGE
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCHHHCCCCHHHCCCCCCHHHHCCCHH
LAGLPDAVLLEVGPGQTLTRLAQPQGDASFAAFATMRHRDDRRSDRRALLAAVGKAWEYG
HHCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VDIDWSLFSGGRRPARVELPGYPFERQRYWIAPSDGIQPIASPEATVPVWRSTTPVIPAA
CCCEEHHHCCCCCCEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCC
ELPTARWLVLVGEGTEARQFAAEFAETIGTAVDLLEPGLAPASGEYEHVVFLGDAHAARI
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHC
DRDRYAQLVDAVDVAGSGVSVHVCLSNAFDVTGAEELDARQWLAFGAAQWLRRSAEARTV
CHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
DVVDMDRPDVRTLIAELSVPGVNRTVAYRNGRRWILDGEPVQGTAAAWSNAAADLRGESI
EEEECCCCHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCCCHHHHHCCCHHHCCCCEE
EVGAVQGSASASNALDDLCTRHVCAHLRSAGVALTPGAEFSRAELIARLGVVPDYHKMVD
EEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHCCCCCHHHHHH
AFIRILSEDGIVASENGRLRVLKEAPTAVPDLGRWCADHPELASWAQLLDQCVGGYDDVL
HHHHHHHCCCEEECCCCCEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCHHHHH
RGRIAGNEVVTPGGDDGLYRTVTEQRIVHSDFATYRDLIGRTLAGLAVNASPARPLRVLE
HCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCEEEEE
IGAGRGYLTWPVIHALRGLPPGAVEYHVTDIGRSFVVAAQQQAESEGLDFVRFAALDIVA
ECCCCCEEHHHHHHHHHCCCCCCEEEEEECCCCHHEEHHHHHHHHCCCCCHHHHHHHHEE
DPAGQSVPLDAFDVVLAFNVLHVAPDLTGAIRNTAAFTAPGGLVFILEATCEGRGDSLID
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCEEECCCCEEEEEEECCCCCCCHHHH
PLLTGWLDFDDDMRTDSPLVAPQQWAALLDANGFAGSTIYDSGPAGDHALIIAERPEPVR
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
TLHPDFDRAVAAIEEIAASEPSAQRMMLTGPGTESIDAAMTEAYAHGTLAVRYRAGVADW
CCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCCE
TFVDSSACGASAVTPDRLAEVLTAPAVPAIALCGPTATAAHEGQESVPMPKESASANSSF
EEECCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCCCCCCCCCCCCCCCC
NQRPTLATEYCAPRSELEERIAAIWRRFFGYDRIGVNDRFLELGGESLLAMQIAAEQRNA
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEEHHHHHHCCC
LGIEVSMRQLLESTTVADIAAAMTNVPTKQDASTPPTPPARRGRAARRTADGVILLEGVH
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCHHHHCCCCEEEEECCC
E
C
>Mature Secondary Structure 
TVEMDAPTTETGLADIAIVGMQCRFAGADDVDKYWSLLSEKREGARSLDGLAAAPGWVR
EEECCCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
REAAIDGIELFDATFFGYPPAEAAMIDPQHRLFLECAYHVFEQAGYDPDRYEGLVGVYAG
HHHHCCCHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEC
SGQSSYLIANVLPHLGVSPSSADALPAGFANSPGSLPGRVSYHLNLTGPSIAVSTACSTS
CCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEHHHHHH
LVAVHLACQELLDYRCDLALAGGVSLNPHPGKGYRHTPNGPLSPDGRCRAFDAAAAGMFP
HHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHCCCCC
GDGVGVVLLKRLSDALADGDRIRAVVKGSAVNNDGRHKTGFTAPSVTAQSEVIMAAHAVA
CCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
GVEASSIGMVEAHGTGTPVGDPIEVAALTKAFRESTDRTGYCMLGSAKTNIGHTDTAAGV
CCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHH
AGLIKAVLSIEHGVIPANLHYSAENPLLDLAGSPFRVAADTVDWPEGDGPRRAGVSAFGI
HHHHHHHHHHHCCCEECEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEC
GGTNAHVVLEQAPDHVEAESPGTDGGLESLLVLSAATPSALDQQAKQLADYVRSNSEVDP
CCCCEEEEEECCCCCCCCCCCCCCCCHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCH
ADVADTLQWGRRKLPYRRSVVCGSAKQAVSLLTAPAQATRASDGAVPLVLLLPGGGAQYV
HHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHCCHHHHCCCCCCCEEEEEECCCCCEEE
GMGRGLYETEEVFRSSIDQCAQILVQHCDIDLRSHLYGDGGLDEQRLDVVFPAVVATEYA
ECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LATQLAAWGLTPNAMLGHSLGEYTAACLSGVIDIDQVLPLVSARGRLFARMGGATTSILL
HHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHCCCEEECCCCCCEEEEE
PTADVTPLLSGRLVVSGITDASSCTVSGPAAEIGALEQELEIRGVQFQRVRVSMAVHSPE
ECCCCCHHHCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCC
LDPVLGEFADILAGVTLRPPRVPYLSNVTGTWIRPEEAIDPGYWIRHSREPVQLAAGFGE
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCHHHCCCCHHHCCCCCCHHHHCCCHH
LAGLPDAVLLEVGPGQTLTRLAQPQGDASFAAFATMRHRDDRRSDRRALLAAVGKAWEYG
HHCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VDIDWSLFSGGRRPARVELPGYPFERQRYWIAPSDGIQPIASPEATVPVWRSTTPVIPAA
CCCEEHHHCCCCCCEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCC
ELPTARWLVLVGEGTEARQFAAEFAETIGTAVDLLEPGLAPASGEYEHVVFLGDAHAARI
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHC
DRDRYAQLVDAVDVAGSGVSVHVCLSNAFDVTGAEELDARQWLAFGAAQWLRRSAEARTV
CHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
DVVDMDRPDVRTLIAELSVPGVNRTVAYRNGRRWILDGEPVQGTAAAWSNAAADLRGESI
EEEECCCCHHHHHHHHHCCCCCCEEEEEECCCEEEECCCCCCCHHHHHCCCHHHCCCCEE
EVGAVQGSASASNALDDLCTRHVCAHLRSAGVALTPGAEFSRAELIARLGVVPDYHKMVD
EEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHCCCCCHHHHHH
AFIRILSEDGIVASENGRLRVLKEAPTAVPDLGRWCADHPELASWAQLLDQCVGGYDDVL
HHHHHHHCCCEEECCCCCEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHCCCHHHHH
RGRIAGNEVVTPGGDDGLYRTVTEQRIVHSDFATYRDLIGRTLAGLAVNASPARPLRVLE
HCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCEEEEE
IGAGRGYLTWPVIHALRGLPPGAVEYHVTDIGRSFVVAAQQQAESEGLDFVRFAALDIVA
ECCCCCEEHHHHHHHHHCCCCCCEEEEEECCCCHHEEHHHHHHHHCCCCCHHHHHHHHEE
DPAGQSVPLDAFDVVLAFNVLHVAPDLTGAIRNTAAFTAPGGLVFILEATCEGRGDSLID
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCEEECCCCEEEEEEECCCCCCCHHHH
PLLTGWLDFDDDMRTDSPLVAPQQWAALLDANGFAGSTIYDSGPAGDHALIIAERPEPVR
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
TLHPDFDRAVAAIEEIAASEPSAQRMMLTGPGTESIDAAMTEAYAHGTLAVRYRAGVADW
CCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCCCCE
TFVDSSACGASAVTPDRLAEVLTAPAVPAIALCGPTATAAHEGQESVPMPKESASANSSF
EEECCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHCCCCCCCCCCCCCCCCCCCC
NQRPTLATEYCAPRSELEERIAAIWRRFFGYDRIGVNDRFLELGGESLLAMQIAAEQRNA
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEEEHHHHHHCCC
LGIEVSMRQLLESTTVADIAAAMTNVPTKQDASTPPTPPARRGRAARRTADGVILLEGVH
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCHHHHCCCCEEEEECCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2024119; 8386127 [H]