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The map label for this gene is eryA [H]

Identifier: 169629342

GI number: 169629342

Start: 2288717

End: 2292490

Strand: Direct

Name: eryA [H]

Synonym: MAB_2256

Alternate gene names: 169629342

Gene position: 2288717-2292490 (Clockwise)

Preceding gene: 169629341

Following gene: 169629343

Centisome position: 45.17

GC content: 63.62

Gene sequence:

>3774_bases
ATGCAGCACTCTTCAACAGCGGCGGAACTTCAGCGCAAATGGCTGCGGGGGGGAGCTTTCGAACCCGATCGGCATCCCGC
GTTGGTGGTGTTCCCGCATGCGGGCGGTGGAGCGACCTTCTACCGCTCGTGGTTGACCAATCCGGATTTCTCGGTGCATG
TCGTGCAGTATCCGGGGCGCGAGGACCGAATTTCCGAACAACTACCGTCGAGTCTGGGCGCGCTCGCCGACGGTGTGGCT
GAGGCGTTGTTGACCGTGGGCGATCGGCCGCTTTATCTGTTCGGCCACAGCATGGGAGCACTGGTGGCCTTTGAGGTCGC
GCGGCGGTTGGAGACGGCGGACAGATTTCGGCAGCTCCGGTTATGTGTCTCCTCGTACACGGCGCCGCACCTGGTCCGTA
GCCGCGGATTACGGGACATGGATGATGAAGCGTTCGTCGCGTACGGACGTTCGGCCACGGGCGAGGTGAGCGCCGCCACG
GGTGAAGCCAGCGCGTTCGATGTAACGGCGCTGCGTGATCTGGTCGTTGCGGGTCTGCGGGCAGATTTTCACCTCGTCGA
GCAATACCGGGCAGAGCCGAAACCTCCAGTGGATGCACCGATTCTCGCGCTGTGGGGCGATGATGAAGCGATCGATCCAG
CGGATATGGATCTTTGGGCCGACGTGACACGAGGTGGCTATCGATCGGCGACCTTTCCTGGCGGACATTTCTACCTCGCC
GCCGAGCGGGACGCGGTTCTGGAGACCGTGCGCCAGTGGTGGGCAGAACTCGACGGCGAGTCGGAAGCCAGTGAGGTCCA
CGAGGTTCGGGACGACGACGTGGCGGTGATCGGAATCGCTGCCCGGGTGCCCGGTGCCGCCAGTCTCGACGAGTTCTGGA
CGAATCTTTGTGCGGGAGAGGAATCCCTCACTCGGTTCACTGATGAGGAACTGCTGTCGGCGGGTGTCACGCCCGAGGAA
CTTCGCGATCCGCGATTGGTGCGGGTTCGGCCGATTCTGGCCGATGTGGCCGACTTCGATACCAAGTTTTTCGGATATGC
TCCTAGCGAGGCGCGCTCAATTGATCCGCAGCAGCGGCTCTTCCTCGAATGCGCTTGGGAAGCCGTCGAATCGGCAGGTT
ATGACCTGCAGCGGTACGACGGCTCGGTCGGTGTGTTCGGAGGCAGTGCCGGTTCGACGTACTACAGGGCAGTCCTGTCA
ACGGATTACGGAAATCTCAACGGAACCGAATATCTGCAGACCGCGCTGGCTACCGAGAACGATTTCCTGGCGCCCCGCGT
CTCCTACAAGCTGAATTTGCGCGGTCCCAGTATCTCGTTGGGCACGGGTTGCTCTACCTCGCTGGTTGCCATTCACCTTG
CGGTACAGAGTGTTTTGACCGGTGAATCTGACATGGCACTGGCCGGTGGCGCCTCCATCACCTTTCCGCAGACTGCCGGA
TATGTGGCTACCGAGAGCGGAGCCATTTCCACGTCCGGTCGGTGCCGGGCATTTGACGCGTCCGCCGACGGCACGTTGGT
CGGTGACGGCATCGGCATAGTCCTGCTCAAACGTGCGTCAAACGCTGTCGCGGACGGTGATTCGATACTGGGAATTATCA
GGGGAACCGCCGTCAACAACGATGGCGGAAACAAGGCCGGCTTTGCGGCGCCCAGTATCAGTGGTCAGGTTGAGGTCATC
ACGGAGGCGCTGGCGGTAGCCGAGGTGCCGGCACAGACTGTCGATTATGTGGAGACACACGGCACCGGTACGCCCCTGGG
CGACCCGATCGAGATCGCCGCTTTGCACAAAGCCTTTCGCGAAGCCGGGGACACGCGAACACAGGCCTGCCGGCTCGGCA
CACTGAAGCCGAATATCGGACACACGGGACCTGCGTCCGGAGTCCTCGCCCTTATCAAGGTCTTGCTGGCGTTTCAGCAC
CGGATGTATCCGCCCGCCGCCAACTTCACGGCGCCCAACCCGCAGATCGAATTCTCAAAGAGCCCCTTCTACGTGGGGAC
GAGGCTGCGGCGCTGGAATGCACCGGGCGGAAAGCCGCGTCGCGCGGGTGTCAGTTCGTACAGCATGGGCGGTACCAATG
CCCATGCCGTACTGCAGGAACCGCCGCGTGCCGAGCTGCCTCCCAAGTCTCAAGAGGGCGCGCACCTGCTGGTGCTCTCT
GCACGCACCGCTCCGGCTCTCGAGGCCGCCCGGAAGAATCTGGCGCACCATCTGGCACGGCATCCCGAACAAGATCTGGC
AGCTGTTGCCGCCACATTGCGTCTGGGGCGGCGAGCTTTCAGCCATCGGTTCGCCGCGGTATGCGCGGACAGGCCCGAGG
CGCTACAGGTGCTCGAAGGCACAGGGCATGCTCCATTTCGGACCGGCACCGCCGCGGACAAGCCCCGGCCGGTTGTGTTT
CTGTTTCCTGGGCAGGGCAGCCAGTTCAGTGGCATGGGCGAACAGCTGTACACGACGTCGTCCATGTACCGCAGGCACAT
CGATGAGTGCGCAACTCTGTTCGAGCCGTTGATCGGGGTGGATCTGCGCACGATGTTGTGTGCCGAGGGAGATGAGGCCA
CGGACGCGGCGCTCATGCAGACTCGCCTGACACAGCCCGCGCTGTTCACGGTCGGATACGCGCTTTCCCAGCTCCTCGGT
GCATGGGGTGTGCAACCCGTCGCCATGCTCGGCCACAGCATCGGTGAGCTGGTCGCCGCCTGCGCTGCCGGAGTATTCAC
GATCGAGGAGGCAGTTCAGCTGGCGGCACGGCGCGGTGACCTGATCCAGCAGTGCCCATCCGGCGCGATGGCCGCGGTCG
GCGGGTCACTCGAGGTCGTTTCCGCGCTGCTGCCCGAAGGAGTGTCGGTGGCCGCTGTCAACGGCCCGGAGCAAATCGTT
GTCGCCGGCAGGGAAGAGGGGATCGAGGCACTCCTGAGTACGGGAGCGAATGTGGGTGTGCGTTGTACCCGCCTACCGGT
GAATCGGGGCTTCCACTCCGCGCTGGTGGACCCGGCGGTCAGCAGTTTCTCGGCCGCCGTGGCGCGGATGCGGTTACAAC
AGCCGCAGGTCCCATTCATATCTAATGTGACGGGTACCTGGATCACCGGGGCGCAGGCTACCGAACCCGAGTACTGGGGT
CGGCAGCTGCGTGAGACGGTGCAGTTCGCGCGCGGCCTGACCACGCTGTGTGCCGAGTACCCGGACGCGCTGCTTGTCGA
GGTCGGTCCCGGTCATACCCTGCGTGGCATTGTTGCCGCGAATACGCCGGCATCCGAAGTTGTTTCGATGCTGGGCGATC
GGACCGGCGACAGTGCGACCGTCGCCTTGGCGGCAGCCGGGCGCTTGTGGGCGGGTGGCGCCGAGCTGGCATGGCAGCAC
TTCGGCGCATCACGGCCACGGGTACCCTTGCCCACCTATCCTTTTGAACGGGAGCGGTTGTGGATGAGTCCGCCGCGTTC
TGTTCTCGACAAACCGGTGCAGGCACCCATTGCGCCCGCTGTGCAGGTGCCGTTGGTGACCGCGTCCACCCAGACCGATG
TACCGGATGCGGCTGTGGTGGAACAGATCTGGTGCGAGGCCCTTGGGGTACCGAGTGTTGAGTCAGACGACAACTTCTTC
GACCTGGGGGGTGATTCCCTGATCGCGGCTCGCGTCGTCACGGCGATAGGGGAGCGCTGCCACATCAAGGTATCGGTAGC
CGAACTCTGGGACCAGGGCGCGACCCTCGCCGATCTTGCCGAATTGGTAGAGCGCCGTGCCATCAACAGCAAGGTGGGAG
AACAACTTAAGTGA

Upstream 100 bases:

>100_bases
ACGGCGGCGGGCTCGTCGCCGCGCGCACTCGAGCCGAGCGTGGGCGTGATGCCCGGGCTCAGCGTCTATCACAGCAACGG
CAAAGGCGGTAGATCCAGTG

Downstream 100 bases:

>100_bases
CCGTGGAGATGGATGCACCGACCACCGAGACAGGGCTGGCCGATATTGCCATCGTCGGGATGCAGTGCCGCTTCGCCGGA
GCCGATGACGTCGACAAGTA

Product: polyketide synthase

Products: NA

Alternate protein names: 6-deoxyerythronolide B synthase I; DEBS 1; ORF 1 [H]

Number of amino acids: Translated: 1257; Mature: 1257

Protein sequence:

>1257_residues
MQHSSTAAELQRKWLRGGAFEPDRHPALVVFPHAGGGATFYRSWLTNPDFSVHVVQYPGREDRISEQLPSSLGALADGVA
EALLTVGDRPLYLFGHSMGALVAFEVARRLETADRFRQLRLCVSSYTAPHLVRSRGLRDMDDEAFVAYGRSATGEVSAAT
GEASAFDVTALRDLVVAGLRADFHLVEQYRAEPKPPVDAPILALWGDDEAIDPADMDLWADVTRGGYRSATFPGGHFYLA
AERDAVLETVRQWWAELDGESEASEVHEVRDDDVAVIGIAARVPGAASLDEFWTNLCAGEESLTRFTDEELLSAGVTPEE
LRDPRLVRVRPILADVADFDTKFFGYAPSEARSIDPQQRLFLECAWEAVESAGYDLQRYDGSVGVFGGSAGSTYYRAVLS
TDYGNLNGTEYLQTALATENDFLAPRVSYKLNLRGPSISLGTGCSTSLVAIHLAVQSVLTGESDMALAGGASITFPQTAG
YVATESGAISTSGRCRAFDASADGTLVGDGIGIVLLKRASNAVADGDSILGIIRGTAVNNDGGNKAGFAAPSISGQVEVI
TEALAVAEVPAQTVDYVETHGTGTPLGDPIEIAALHKAFREAGDTRTQACRLGTLKPNIGHTGPASGVLALIKVLLAFQH
RMYPPAANFTAPNPQIEFSKSPFYVGTRLRRWNAPGGKPRRAGVSSYSMGGTNAHAVLQEPPRAELPPKSQEGAHLLVLS
ARTAPALEAARKNLAHHLARHPEQDLAAVAATLRLGRRAFSHRFAAVCADRPEALQVLEGTGHAPFRTGTAADKPRPVVF
LFPGQGSQFSGMGEQLYTTSSMYRRHIDECATLFEPLIGVDLRTMLCAEGDEATDAALMQTRLTQPALFTVGYALSQLLG
AWGVQPVAMLGHSIGELVAACAAGVFTIEEAVQLAARRGDLIQQCPSGAMAAVGGSLEVVSALLPEGVSVAAVNGPEQIV
VAGREEGIEALLSTGANVGVRCTRLPVNRGFHSALVDPAVSSFSAAVARMRLQQPQVPFISNVTGTWITGAQATEPEYWG
RQLRETVQFARGLTTLCAEYPDALLVEVGPGHTLRGIVAANTPASEVVSMLGDRTGDSATVALAAAGRLWAGGAELAWQH
FGASRPRVPLPTYPFERERLWMSPPRSVLDKPVQAPIAPAVQVPLVTASTQTDVPDAAVVEQIWCEALGVPSVESDDNFF
DLGGDSLIAARVVTAIGERCHIKVSVAELWDQGATLADLAELVERRAINSKVGEQLK

Sequences:

>Translated_1257_residues
MQHSSTAAELQRKWLRGGAFEPDRHPALVVFPHAGGGATFYRSWLTNPDFSVHVVQYPGREDRISEQLPSSLGALADGVA
EALLTVGDRPLYLFGHSMGALVAFEVARRLETADRFRQLRLCVSSYTAPHLVRSRGLRDMDDEAFVAYGRSATGEVSAAT
GEASAFDVTALRDLVVAGLRADFHLVEQYRAEPKPPVDAPILALWGDDEAIDPADMDLWADVTRGGYRSATFPGGHFYLA
AERDAVLETVRQWWAELDGESEASEVHEVRDDDVAVIGIAARVPGAASLDEFWTNLCAGEESLTRFTDEELLSAGVTPEE
LRDPRLVRVRPILADVADFDTKFFGYAPSEARSIDPQQRLFLECAWEAVESAGYDLQRYDGSVGVFGGSAGSTYYRAVLS
TDYGNLNGTEYLQTALATENDFLAPRVSYKLNLRGPSISLGTGCSTSLVAIHLAVQSVLTGESDMALAGGASITFPQTAG
YVATESGAISTSGRCRAFDASADGTLVGDGIGIVLLKRASNAVADGDSILGIIRGTAVNNDGGNKAGFAAPSISGQVEVI
TEALAVAEVPAQTVDYVETHGTGTPLGDPIEIAALHKAFREAGDTRTQACRLGTLKPNIGHTGPASGVLALIKVLLAFQH
RMYPPAANFTAPNPQIEFSKSPFYVGTRLRRWNAPGGKPRRAGVSSYSMGGTNAHAVLQEPPRAELPPKSQEGAHLLVLS
ARTAPALEAARKNLAHHLARHPEQDLAAVAATLRLGRRAFSHRFAAVCADRPEALQVLEGTGHAPFRTGTAADKPRPVVF
LFPGQGSQFSGMGEQLYTTSSMYRRHIDECATLFEPLIGVDLRTMLCAEGDEATDAALMQTRLTQPALFTVGYALSQLLG
AWGVQPVAMLGHSIGELVAACAAGVFTIEEAVQLAARRGDLIQQCPSGAMAAVGGSLEVVSALLPEGVSVAAVNGPEQIV
VAGREEGIEALLSTGANVGVRCTRLPVNRGFHSALVDPAVSSFSAAVARMRLQQPQVPFISNVTGTWITGAQATEPEYWG
RQLRETVQFARGLTTLCAEYPDALLVEVGPGHTLRGIVAANTPASEVVSMLGDRTGDSATVALAAAGRLWAGGAELAWQH
FGASRPRVPLPTYPFERERLWMSPPRSVLDKPVQAPIAPAVQVPLVTASTQTDVPDAAVVEQIWCEALGVPSVESDDNFF
DLGGDSLIAARVVTAIGERCHIKVSVAELWDQGATLADLAELVERRAINSKVGEQLK
>Mature_1257_residues
MQHSSTAAELQRKWLRGGAFEPDRHPALVVFPHAGGGATFYRSWLTNPDFSVHVVQYPGREDRISEQLPSSLGALADGVA
EALLTVGDRPLYLFGHSMGALVAFEVARRLETADRFRQLRLCVSSYTAPHLVRSRGLRDMDDEAFVAYGRSATGEVSAAT
GEASAFDVTALRDLVVAGLRADFHLVEQYRAEPKPPVDAPILALWGDDEAIDPADMDLWADVTRGGYRSATFPGGHFYLA
AERDAVLETVRQWWAELDGESEASEVHEVRDDDVAVIGIAARVPGAASLDEFWTNLCAGEESLTRFTDEELLSAGVTPEE
LRDPRLVRVRPILADVADFDTKFFGYAPSEARSIDPQQRLFLECAWEAVESAGYDLQRYDGSVGVFGGSAGSTYYRAVLS
TDYGNLNGTEYLQTALATENDFLAPRVSYKLNLRGPSISLGTGCSTSLVAIHLAVQSVLTGESDMALAGGASITFPQTAG
YVATESGAISTSGRCRAFDASADGTLVGDGIGIVLLKRASNAVADGDSILGIIRGTAVNNDGGNKAGFAAPSISGQVEVI
TEALAVAEVPAQTVDYVETHGTGTPLGDPIEIAALHKAFREAGDTRTQACRLGTLKPNIGHTGPASGVLALIKVLLAFQH
RMYPPAANFTAPNPQIEFSKSPFYVGTRLRRWNAPGGKPRRAGVSSYSMGGTNAHAVLQEPPRAELPPKSQEGAHLLVLS
ARTAPALEAARKNLAHHLARHPEQDLAAVAATLRLGRRAFSHRFAAVCADRPEALQVLEGTGHAPFRTGTAADKPRPVVF
LFPGQGSQFSGMGEQLYTTSSMYRRHIDECATLFEPLIGVDLRTMLCAEGDEATDAALMQTRLTQPALFTVGYALSQLLG
AWGVQPVAMLGHSIGELVAACAAGVFTIEEAVQLAARRGDLIQQCPSGAMAAVGGSLEVVSALLPEGVSVAAVNGPEQIV
VAGREEGIEALLSTGANVGVRCTRLPVNRGFHSALVDPAVSSFSAAVARMRLQQPQVPFISNVTGTWITGAQATEPEYWG
RQLRETVQFARGLTTLCAEYPDALLVEVGPGHTLRGIVAANTPASEVVSMLGDRTGDSATVALAAAGRLWAGGAELAWQH
FGASRPRVPLPTYPFERERLWMSPPRSVLDKPVQAPIAPAVQVPLVTASTQTDVPDAAVVEQIWCEALGVPSVESDDNFF
DLGGDSLIAARVVTAIGERCHIKVSVAELWDQGATLADLAELVERRAINSKVGEQLK

Specific function: Fatty acid biosynthesis. [C]

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=869, Percent_Identity=29.3440736478711, Blast_Score=289, Evalue=1e-77,
Organism=Homo sapiens, GI89257335, Length=224, Percent_Identity=32.5892857142857, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI8923559, Length=281, Percent_Identity=26.6903914590747, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI8922871, Length=194, Percent_Identity=32.4742268041237, Blast_Score=79, Evalue=4e-14,
Organism=Escherichia coli, GI1787334, Length=292, Percent_Identity=31.8493150684932, Blast_Score=103, Evalue=7e-23,
Organism=Escherichia coli, GI1788663, Length=232, Percent_Identity=30.1724137931034, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1787337, Length=251, Percent_Identity=28.2868525896414, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17550940, Length=865, Percent_Identity=28.4393063583815, Blast_Score=301, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI212642053, Length=721, Percent_Identity=30.0970873786408, Blast_Score=296, Evalue=6e-80,
Organism=Caenorhabditis elegans, GI71983541, Length=285, Percent_Identity=26.3157894736842, Blast_Score=87, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71983535, Length=272, Percent_Identity=26.1029411764706, Blast_Score=80, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320904, Length=450, Percent_Identity=24, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI221330659, Length=867, Percent_Identity=28.4890426758939, Blast_Score=274, Evalue=3e-73,
Organism=Drosophila melanogaster, GI19920632, Length=867, Percent_Identity=28.4890426758939, Blast_Score=273, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24581345, Length=896, Percent_Identity=27.5669642857143, Blast_Score=261, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24644341, Length=447, Percent_Identity=27.5167785234899, Blast_Score=97, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24665753, Length=318, Percent_Identity=28.3018867924528, Blast_Score=70, Evalue=1e-11,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR013968
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.94 [H]

Molecular weight: Translated: 133708; Mature: 133708

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHSSTAAELQRKWLRGGAFEPDRHPALVVFPHAGGGATFYRSWLTNPDFSVHVVQYPGR
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCEEEEEECCCC
EDRISEQLPSSLGALADGVAEALLTVGDRPLYLFGHSMGALVAFEVARRLETADRFRQLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LCVSSYTAPHLVRSRGLRDMDDEAFVAYGRSATGEVSAATGEASAFDVTALRDLVVAGLR
HHHHHCCCHHHHHHCCCCCCCCCHHEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHH
ADFHLVEQYRAEPKPPVDAPILALWGDDEAIDPADMDLWADVTRGGYRSATFPGGHFYLA
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEE
AERDAVLETVRQWWAELDGESEASEVHEVRDDDVAVIGIAARVPGAASLDEFWTNLCAGE
ECHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCH
ESLTRFTDEELLSAGVTPEELRDPRLVRVRPILADVADFDTKFFGYAPSEARSIDPQQRL
HHHHHHCHHHHHHCCCCHHHHCCCCEEEEHHHHHHHHHHCCHHCCCCCCHHCCCCHHHHH
FLECAWEAVESAGYDLQRYDGSVGVFGGSAGSTYYRAVLSTDYGNLNGTEYLQTALATEN
HHHHHHHHHHHCCCCHHHCCCCEEEECCCCCCHHEEHEEECCCCCCCCHHHHHHHHHCCC
DFLAPRVSYKLNLRGPSISLGTGCSTSLVAIHLAVQSVLTGESDMALAGGASITFPQTAG
CCCCCCEEEEEEECCCCEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCEEECCCCCC
YVATESGAISTSGRCRAFDASADGTLVGDGIGIVLLKRASNAVADGDSILGIIRGTAVNN
EEEECCCCCCCCCCEEEEECCCCCCEEECCCEEEEEECCCCCCCCCCCEEEEEEEEEECC
DGGNKAGFAAPSISGQVEVITEALAVAEVPAQTVDYVETHGTGTPLGDPIEIAALHKAFR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
EAGDTRTQACRLGTLKPNIGHTGPASGVLALIKVLLAFQHRMYPPAANFTAPNPQIEFSK
HCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECC
SPFYVGTRLRRWNAPGGKPRRAGVSSYSMGGTNAHAVLQEPPRAELPPKSQEGAHLLVLS
CCEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCEEEEEE
ARTAPALEAARKNLAHHLARHPEQDLAAVAATLRLGRRAFSHRFAAVCADRPEALQVLEG
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
TGHAPFRTGTAADKPRPVVFLFPGQGSQFSGMGEQLYTTSSMYRRHIDECATLFEPLIGV
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DLRTMLCAEGDEATDAALMQTRLTQPALFTVGYALSQLLGAWGVQPVAMLGHSIGELVAA
CHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
CAAGVFTIEEAVQLAARRGDLIQQCPSGAMAAVGGSLEVVSALLPEGVSVAAVNGPEQIV
HHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHCCCHHHHHHHHCCCCCEEEEECCCCEEE
VAGREEGIEALLSTGANVGVRCTRLPVNRGFHSALVDPAVSSFSAAVARMRLQQPQVPFI
EECCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SNVTGTWITGAQATEPEYWGRQLRETVQFARGLTTLCAEYPDALLVEVGPGHTLRGIVAA
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEC
NTPASEVVSMLGDRTGDSATVALAAAGRLWAGGAELAWQHFGASRPRVPLPTYPFERERL
CCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCE
WMSPPRSVLDKPVQAPIAPAVQVPLVTASTQTDVPDAAVVEQIWCEALGVPSVESDDNFF
ECCCCHHHHCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEE
DLGGDSLIAARVVTAIGERCHIKVSVAELWDQGATLADLAELVERRAINSKVGEQLK
ECCCCHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQHSSTAAELQRKWLRGGAFEPDRHPALVVFPHAGGGATFYRSWLTNPDFSVHVVQYPGR
CCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCEEEEEECCCC
EDRISEQLPSSLGALADGVAEALLTVGDRPLYLFGHSMGALVAFEVARRLETADRFRQLR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LCVSSYTAPHLVRSRGLRDMDDEAFVAYGRSATGEVSAATGEASAFDVTALRDLVVAGLR
HHHHHCCCHHHHHHCCCCCCCCCHHEEECCCCCCCCEECCCCCCHHHHHHHHHHHHHHHH
ADFHLVEQYRAEPKPPVDAPILALWGDDEAIDPADMDLWADVTRGGYRSATFPGGHFYLA
HHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEEEE
AERDAVLETVRQWWAELDGESEASEVHEVRDDDVAVIGIAARVPGAASLDEFWTNLCAGE
ECHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCH
ESLTRFTDEELLSAGVTPEELRDPRLVRVRPILADVADFDTKFFGYAPSEARSIDPQQRL
HHHHHHCHHHHHHCCCCHHHHCCCCEEEEHHHHHHHHHHCCHHCCCCCCHHCCCCHHHHH
FLECAWEAVESAGYDLQRYDGSVGVFGGSAGSTYYRAVLSTDYGNLNGTEYLQTALATEN
HHHHHHHHHHHCCCCHHHCCCCEEEECCCCCCHHEEHEEECCCCCCCCHHHHHHHHHCCC
DFLAPRVSYKLNLRGPSISLGTGCSTSLVAIHLAVQSVLTGESDMALAGGASITFPQTAG
CCCCCCEEEEEEECCCCEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCEEECCCCCC
YVATESGAISTSGRCRAFDASADGTLVGDGIGIVLLKRASNAVADGDSILGIIRGTAVNN
EEEECCCCCCCCCCEEEEECCCCCCEEECCCEEEEEECCCCCCCCCCCEEEEEEEEEECC
DGGNKAGFAAPSISGQVEVITEALAVAEVPAQTVDYVETHGTGTPLGDPIEIAALHKAFR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
EAGDTRTQACRLGTLKPNIGHTGPASGVLALIKVLLAFQHRMYPPAANFTAPNPQIEFSK
HCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECC
SPFYVGTRLRRWNAPGGKPRRAGVSSYSMGGTNAHAVLQEPPRAELPPKSQEGAHLLVLS
CCEEECCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCEEEEEE
ARTAPALEAARKNLAHHLARHPEQDLAAVAATLRLGRRAFSHRFAAVCADRPEALQVLEG
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
TGHAPFRTGTAADKPRPVVFLFPGQGSQFSGMGEQLYTTSSMYRRHIDECATLFEPLIGV
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DLRTMLCAEGDEATDAALMQTRLTQPALFTVGYALSQLLGAWGVQPVAMLGHSIGELVAA
CHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
CAAGVFTIEEAVQLAARRGDLIQQCPSGAMAAVGGSLEVVSALLPEGVSVAAVNGPEQIV
HHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHCCCHHHHHHHHCCCCCEEEEECCCCEEE
VAGREEGIEALLSTGANVGVRCTRLPVNRGFHSALVDPAVSSFSAAVARMRLQQPQVPFI
EECCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SNVTGTWITGAQATEPEYWGRQLRETVQFARGLTTLCAEYPDALLVEVGPGHTLRGIVAA
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEC
NTPASEVVSMLGDRTGDSATVALAAAGRLWAGGAELAWQHFGASRPRVPLPTYPFERERL
CCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCE
WMSPPRSVLDKPVQAPIAPAVQVPLVTASTQTDVPDAAVVEQIWCEALGVPSVESDDNFF
ECCCCHHHHCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEE
DLGGDSLIAARVVTAIGERCHIKVSVAELWDQGATLADLAELVERRAINSKVGEQLK
ECCCCHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2024119; 8386127 [H]