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The map label for this gene is ywbI [H]

Identifier: 169629324

GI number: 169629324

Start: 2264064

End: 2264933

Strand: Direct

Name: ywbI [H]

Synonym: MAB_2238

Alternate gene names: 169629324

Gene position: 2264064-2264933 (Clockwise)

Preceding gene: 169629321

Following gene: 169629325

Centisome position: 44.68

GC content: 66.21

Gene sequence:

>870_bases
ATGGAGATTCACCAGCTGCGCTATCTGCTGGCGGTGGCCGACACATCGAGCTTCACGAAGGCGGCCGCCGCATTGCATGT
CGCCCAACCCGGCGTGAGCGCCCAAATCCGGCTTCTGGAACGCGAACTGGGGCAGGACTTGTTCGATCGATCGGGGCGCC
AAGTCCGGCTTACCGATGCCGGCAAGGCGGTGATTCCCTACGCGCGAGCCGCGCTCGCCGCTGTGGACGGTGTGCGTGAG
GCGGCTGACGAGATCGGCGGACTCATCCGGGGGCATATCGCATTCGGAACCGTGACATCACACGGCGCAGATCTCTCCTC
ATTGCTTTCGGCGTTTCATCGTGACCATCCCGCCATCTCGATCACCCTCACCGAAGCCGGGTGCGAGGAGCTTGTTGCCG
GGCTGCGCGAGGGCCGGCTGGACGGAGCGATCGTGGCCCTGGGGGCACAACGGCTCGCGGGGCTGGGTCTACAAGTCATT
GACGACCAACCCTTGGTGGCGGCGGTCGCGGCCGATGATCTGTTGGCGACACGGCGCACGATCACGCTGCAAAGATTGTG
CGAGCACACCCTGATCTGCCTGCCCACCGGTAGTGGCGTTCGGTCCATCCTGGAGTCCGAATGCCGGTCGCTCGGGCTCA
GCCCGAATGTGGCCTTTGAAGCGAGTTCGCCGCGAGCCTTGGTAAGTCTCGTAGAACAGGGCCTCGGCATCGCGGTGGTG
CCTGCTCCATACGTGCGAAACCGGGCCGGGGTGCTGGCATTGGACATCCGGCCCGCGCTGCGCGGGCGGCTGGCATTGGC
ATGGCGCCTTGACGGTCCGGTCGGTCCGGCGGCGCGCGCCTTTCTGGAGCGCGCTCGCGCCGTTCTCTGA

Upstream 100 bases:

>100_bases
ACCACGATCGATGTCTTGTCTGTGCTCATATGTTCCAGCATCGGAGGAGGCGGTTCAGAAGTCCAAGATCTATTGGTTAG
TAGACCTATAACCTGTACTT

Downstream 100 bases:

>100_bases
CCGCGGTTCCGATCACCCTGAATGCAACCCGGCGCCGGACGCCATGGTGGCGCAATGGCCCACTCGGGGTGGTGCGCAGC
AGGTCGCAGGTGGTGTGCAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MEIHQLRYLLAVADTSSFTKAAAALHVAQPGVSAQIRLLERELGQDLFDRSGRQVRLTDAGKAVIPYARAALAAVDGVRE
AADEIGGLIRGHIAFGTVTSHGADLSSLLSAFHRDHPAISITLTEAGCEELVAGLREGRLDGAIVALGAQRLAGLGLQVI
DDQPLVAAVAADDLLATRRTITLQRLCEHTLICLPTGSGVRSILESECRSLGLSPNVAFEASSPRALVSLVEQGLGIAVV
PAPYVRNRAGVLALDIRPALRGRLALAWRLDGPVGPAARAFLERARAVL

Sequences:

>Translated_289_residues
MEIHQLRYLLAVADTSSFTKAAAALHVAQPGVSAQIRLLERELGQDLFDRSGRQVRLTDAGKAVIPYARAALAAVDGVRE
AADEIGGLIRGHIAFGTVTSHGADLSSLLSAFHRDHPAISITLTEAGCEELVAGLREGRLDGAIVALGAQRLAGLGLQVI
DDQPLVAAVAADDLLATRRTITLQRLCEHTLICLPTGSGVRSILESECRSLGLSPNVAFEASSPRALVSLVEQGLGIAVV
PAPYVRNRAGVLALDIRPALRGRLALAWRLDGPVGPAARAFLERARAVL
>Mature_289_residues
MEIHQLRYLLAVADTSSFTKAAAALHVAQPGVSAQIRLLERELGQDLFDRSGRQVRLTDAGKAVIPYARAALAAVDGVRE
AADEIGGLIRGHIAFGTVTSHGADLSSLLSAFHRDHPAISITLTEAGCEELVAGLREGRLDGAIVALGAQRLAGLGLQVI
DDQPLVAAVAADDLLATRRTITLQRLCEHTLICLPTGSGVRSILESECRSLGLSPNVAFEASSPRALVSLVEQGLGIAVV
PAPYVRNRAGVLALDIRPALRGRLALAWRLDGPVGPAARAFLERARAVL

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=292, Percent_Identity=32.1917808219178, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI157672245, Length=285, Percent_Identity=34.0350877192982, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787879, Length=290, Percent_Identity=30.6896551724138, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367136, Length=249, Percent_Identity=28.9156626506024, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787530, Length=243, Percent_Identity=27.5720164609054, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=24.9134948096886, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787806, Length=273, Percent_Identity=27.4725274725275, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788887, Length=293, Percent_Identity=30.3754266211604, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=28.1746031746032, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788748, Length=296, Percent_Identity=25, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790208, Length=262, Percent_Identity=27.4809160305344, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=31.7241379310345, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790262, Length=291, Percent_Identity=26.4604810996564, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788481, Length=236, Percent_Identity=25.4237288135593, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788296, Length=253, Percent_Identity=26.4822134387352, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30409; Mature: 30409

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIHQLRYLLAVADTSSFTKAAAALHVAQPGVSAQIRLLERELGQDLFDRSGRQVRLTDA
CCHHHHEEHHHEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHCCCCEEEEECC
GKAVIPYARAALAAVDGVREAADEIGGLIRGHIAFGTVTSHGADLSSLLSAFHRDHPAIS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCEEE
ITLTEAGCEELVAGLREGRLDGAIVALGAQRLAGLGLQVIDDQPLVAAVAADDLLATRRT
EEEECCCHHHHHHHHHHCCCCCCEEEHHHHHHHCCCEEEECCCCEEEEHHHHHHHHHHHH
ITLQRLCEHTLICLPTGSGVRSILESECRSLGLSPNVAFEASSPRALVSLVEQGLGIAVV
HHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCCEEEE
PAPYVRNRAGVLALDIRPALRGRLALAWRLDGPVGPAARAFLERARAVL
CCHHHCCCCCEEEEECCHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIHQLRYLLAVADTSSFTKAAAALHVAQPGVSAQIRLLERELGQDLFDRSGRQVRLTDA
CCHHHHEEHHHEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHCCCCEEEEECC
GKAVIPYARAALAAVDGVREAADEIGGLIRGHIAFGTVTSHGADLSSLLSAFHRDHPAIS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCEEE
ITLTEAGCEELVAGLREGRLDGAIVALGAQRLAGLGLQVIDDQPLVAAVAADDLLATRRT
EEEECCCHHHHHHHHHHCCCCCCEEEHHHHHHHCCCEEEECCCCEEEEHHHHHHHHHHHH
ITLQRLCEHTLICLPTGSGVRSILESECRSLGLSPNVAFEASSPRALVSLVEQGLGIAVV
HHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCCEEEE
PAPYVRNRAGVLALDIRPALRGRLALAWRLDGPVGPAARAFLERARAVL
CCHHHCCCCCEEEEECCHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]