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The map label for this gene is 169629311

Identifier: 169629311

GI number: 169629311

Start: 2247564

End: 2248949

Strand: Reverse

Name: 169629311

Synonym: MAB_2225c

Alternate gene names: NA

Gene position: 2248949-2247564 (Counterclockwise)

Preceding gene: 169629312

Following gene: 169629310

Centisome position: 44.38

GC content: 66.74

Gene sequence:

>1386_bases
ATGACACATTTTATCCGCGATGCGCCGCGCGCGCGAAGAGCATTGGGCGGTGTCGTCGCCGCAACGCTACTGGCGCTGTC
CCCCGTGGCAGCCCCTGTTGCCGGCGCAGTGATTCAGCCGGAAGCAGATCCCGCCGCGTTGCCCAAGGATTCGTCCCCCA
GCGCAACCGCGGGCATGCAATCGTCCGCGTGCAGCACCACGGTGTTACTGCCCGGCACGGGCACCAGCGGCAAGCCGTCG
CCAGAGTTCGAGGAGGCGTGGCGCTTTTCTCGCGGTGAGGGGCAGAGCGTCGCGATCATCGACACCGGCGTCAAACCCAG
TGCGCGACTGCACGTCGAACCCGGGGGCGATTATGTCCAGTCAACGGATGGGCTCACCGACTGCGACGGGCACGGAACCA
TGGTGGCCGGAATCATCGGTGCCCAGCCCGGGCCCGATGGATTCTCCGGTATCGCGCCCGCCGCCAAACTGATCTCGATC
CGCCAGGAGTCCTCCAAGTTCTCCCCACGACTCACCGCGGGAGGCGATCCGTCCACAAACGCCGCTACCCAGTACGTCAA
TACCCTGGCACGGTCCATCGTGCATGCCGCAAACCTCGGCGCCCGCGTGATCAACATTTCTTCGGCCGAGTGCGTTCCGG
CGGCCAAGCCCATTGACCAAGCCGCGCTTGGGGCGGCGTTGCGCTATGCGGTCGCCGAAAAGGACGCGGTCGTCGTGGCC
GCCGCGGGCAACACCAGCGGCGGCAGCGCCAACTGCCAACAGAATCCGTTGACCGGTTCGGGCGCCGACCCACGGAATTG
GTCTGGGGTGGAGTCGGTATCGGTGCCATCCTGGTGGCAGCCGTACGTGCTGTCGGTGGGTTCGGTGGGTATCGACGGAA
GCCCGTCGAAGTTCACCATGGCCGGGCCCTGGGTGGGCATTGCGGCAAATGGCGAGAACGTGACCTCGCTGTCCAACGAC
GCTGAGGGCGGTTTGGCCAACGGCATGATTGGCCAGAACGGAAAGCCGGTGCCCCTCTTCGGGACCAGCTATGCGACAGC
ATACGTAGCGGGTGTGGCTGCGCTGGTACGTAGCCGCTATCCCGAATTGACTGCACCGCAGGTTATTTCGCGGCTGCAAA
GAACAGCCCGAGACGCGGGCCGATCGCCGTCCAATCTGGTGGGAGCCGGAACGGTGGACCCGGTGGCCGCGCTTACCTGG
GAGGTCCCCGCGGACGGGAACGCATCTAGTGGCCCGGGCGCCCGTGCGGTCGTCCCCCCGCCCCCTCCCACCCCGGAAAA
TCCACTTCCCCGGCGGCTCGCCTTCCTGGGCGCCGGTGTATGCCTGATCGCGGTGGTCGTCGTCGCCGCGCTCAGCGCGC
GTCGCAGACAGGAGAGCACTGAGTGA

Upstream 100 bases:

>100_bases
CCAGCCGTCGGCTCCTCGGATTCCTCGCCTCGGGTATCGACGCCTCGCTGCTGCCGGTCATCGCGTACCTCACCGGACTG
TTCAGCTGGATCCTCAACCG

Downstream 100 bases:

>100_bases
GTACCCATGCGAGTAAGAAGTTCACGTTTTATCGACCACCCGTGCCTGGAACGCTGCGGCTGACACTGATCGCCACGCTG
GTTGCCGCGGGTGCTTTCGC

Product: peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MTHFIRDAPRARRALGGVVAATLLALSPVAAPVAGAVIQPEADPAALPKDSSPSATAGMQSSACSTTVLLPGTGTSGKPS
PEFEEAWRFSRGEGQSVAIIDTGVKPSARLHVEPGGDYVQSTDGLTDCDGHGTMVAGIIGAQPGPDGFSGIAPAAKLISI
RQESSKFSPRLTAGGDPSTNAATQYVNTLARSIVHAANLGARVINISSAECVPAAKPIDQAALGAALRYAVAEKDAVVVA
AAGNTSGGSANCQQNPLTGSGADPRNWSGVESVSVPSWWQPYVLSVGSVGIDGSPSKFTMAGPWVGIAANGENVTSLSND
AEGGLANGMIGQNGKPVPLFGTSYATAYVAGVAALVRSRYPELTAPQVISRLQRTARDAGRSPSNLVGAGTVDPVAALTW
EVPADGNASSGPGARAVVPPPPPTPENPLPRRLAFLGAGVCLIAVVVVAALSARRRQESTE

Sequences:

>Translated_461_residues
MTHFIRDAPRARRALGGVVAATLLALSPVAAPVAGAVIQPEADPAALPKDSSPSATAGMQSSACSTTVLLPGTGTSGKPS
PEFEEAWRFSRGEGQSVAIIDTGVKPSARLHVEPGGDYVQSTDGLTDCDGHGTMVAGIIGAQPGPDGFSGIAPAAKLISI
RQESSKFSPRLTAGGDPSTNAATQYVNTLARSIVHAANLGARVINISSAECVPAAKPIDQAALGAALRYAVAEKDAVVVA
AAGNTSGGSANCQQNPLTGSGADPRNWSGVESVSVPSWWQPYVLSVGSVGIDGSPSKFTMAGPWVGIAANGENVTSLSND
AEGGLANGMIGQNGKPVPLFGTSYATAYVAGVAALVRSRYPELTAPQVISRLQRTARDAGRSPSNLVGAGTVDPVAALTW
EVPADGNASSGPGARAVVPPPPPTPENPLPRRLAFLGAGVCLIAVVVVAALSARRRQESTE
>Mature_460_residues
THFIRDAPRARRALGGVVAATLLALSPVAAPVAGAVIQPEADPAALPKDSSPSATAGMQSSACSTTVLLPGTGTSGKPSP
EFEEAWRFSRGEGQSVAIIDTGVKPSARLHVEPGGDYVQSTDGLTDCDGHGTMVAGIIGAQPGPDGFSGIAPAAKLISIR
QESSKFSPRLTAGGDPSTNAATQYVNTLARSIVHAANLGARVINISSAECVPAAKPIDQAALGAALRYAVAEKDAVVVAA
AGNTSGGSANCQQNPLTGSGADPRNWSGVESVSVPSWWQPYVLSVGSVGIDGSPSKFTMAGPWVGIAANGENVTSLSNDA
EGGLANGMIGQNGKPVPLFGTSYATAYVAGVAALVRSRYPELTAPQVISRLQRTARDAGRSPSNLVGAGTVDPVAALTWE
VPADGNASSGPGARAVVPPPPPTPENPLPRRLAFLGAGVCLIAVVVVAALSARRRQESTE

Specific function: Shows keratinolytic activity [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 46513; Mature: 46381

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00137 SUBTILASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHFIRDAPRARRALGGVVAATLLALSPVAAPVAGAVIQPEADPAALPKDSSPSATAGMQ
CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCHHCCCC
SSACSTTVLLPGTGTSGKPSPEFEEAWRFSRGEGQSVAIIDTGVKPSARLHVEPGGDYVQ
CCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCCCCEEE
STDGLTDCDGHGTMVAGIIGAQPGPDGFSGIAPAAKLISIRQESSKFSPRLTAGGDPSTN
CCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCH
AATQYVNTLARSIVHAANLGARVINISSAECVPAAKPIDQAALGAALRYAVAEKDAVVVA
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
AAGNTSGGSANCQQNPLTGSGADPRNWSGVESVSVPSWWQPYVLSVGSVGIDGSPSKFTM
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEE
AGPWVGIAANGENVTSLSNDAEGGLANGMIGQNGKPVPLFGTSYATAYVAGVAALVRSRY
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCC
PELTAPQVISRLQRTARDAGRSPSNLVGAGTVDPVAALTWEVPADGNASSGPGARAVVPP
CCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCCEEECCC
PPPTPENPLPRRLAFLGAGVCLIAVVVVAALSARRRQESTE
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
THFIRDAPRARRALGGVVAATLLALSPVAAPVAGAVIQPEADPAALPKDSSPSATAGMQ
CCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCCCCHHCCCC
SSACSTTVLLPGTGTSGKPSPEFEEAWRFSRGEGQSVAIIDTGVKPSARLHVEPGGDYVQ
CCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCCCCEEE
STDGLTDCDGHGTMVAGIIGAQPGPDGFSGIAPAAKLISIRQESSKFSPRLTAGGDPSTN
CCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCH
AATQYVNTLARSIVHAANLGARVINISSAECVPAAKPIDQAALGAALRYAVAEKDAVVVA
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
AAGNTSGGSANCQQNPLTGSGADPRNWSGVESVSVPSWWQPYVLSVGSVGIDGSPSKFTM
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEE
AGPWVGIAANGENVTSLSNDAEGGLANGMIGQNGKPVPLFGTSYATAYVAGVAALVRSRY
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCC
PELTAPQVISRLQRTARDAGRSPSNLVGAGTVDPVAALTWEVPADGNASSGPGARAVVPP
CCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEEECCCCCCCCCCCCCEEECCC
PPPTPENPLPRRLAFLGAGVCLIAVVVVAALSARRRQESTE
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1369007; 11058132; 1370008 [H]