Click here to switch to the map view.

The map label for this gene is cobK [H]

Identifier: 169629283

GI number: 169629283

Start: 2211809

End: 2212537

Strand: Direct

Name: cobK [H]

Synonym: MAB_2197

Alternate gene names: 169629283

Gene position: 2211809-2212537 (Clockwise)

Preceding gene: 169629282

Following gene: 169629287

Centisome position: 43.65

GC content: 65.16

Gene sequence:

>729_bases
TTGATCCTCGGGGGCTCGGCGGAAGCACGCGAGTTGGCCGAGCGGCTAGCACCCCGATTCGACGTCACCACCTCCCTCGC
GGGACGTGTGAACAACCCCGCGGTCCCCGCCGGTGCGCTGCGGATCGGTGGTTTTGGTGGCGAGGTGGGATTGCGGAAAT
GGTTGTTGGACAACGCTATTGATGCAGTGGTAGATGCCACACACCCGTTTGCGGCGACGATCACCGAGAACGCGGCGGCC
GCGTGCGCGCGGCTGGGCATCCCTCATCTCATCGTGCGGCGTCCACCGTGGCCGGCCGGGGATGCCACCGTGGTGAGCTC
GGCTGCCGAGGCCAAGGATGCGGTGGTGGCGCAGGGCTTCTCGCGAGTGTTTCTCACGTCCGGACGCTCCAGCGTCGGGG
CTTTCCTGTTCTCGGATGCCTGGTTTCTGATCCGGGTGGTGGAGCCGATGTCCGCCGACGAGCTACCCGAAAGACACCAC
CTGCTGTTGTCACGCGGGCCCTACACGGTCGCCGAGGAAACCGAGCTGATGCGCCAATACGAGATCGAGGTTCTGGTCAC
CAAGAACAGTGGTGGCACCATGACCTCGGCCAAGTTGGAAGCGGCAGCGGCGCTGGGCATTCCCGTCGTGATGATTGACA
GGCCCGCGTTGCCGGAGAACGTGTCCACCGTGTCCACCGTGGATGCGGCGCAGCAATGGGTTACCGAGCGGGATAACGCC
GGGGTGTAA

Upstream 100 bases:

>100_bases
TAGGCAAGGTGCTTGCGGCAGAGGGGTTTACCGATAGCTATCTGTATTCCTCGGGACGTCGGAGAGGGGCTTCGCACTGA
TGCCAGCACTAAGGAGAGTC

Downstream 100 bases:

>100_bases
AGACCTGCGGGCCAGAATCGGTGTCGTGCCATTGGGTCTGCGACGAGCCGATGATCAGTAGGGTACGCATGTCCACCACG
GTGGGGTCGAGCTCGCCCAG

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MILGGSAEARELAERLAPRFDVTTSLAGRVNNPAVPAGALRIGGFGGEVGLRKWLLDNAIDAVVDATHPFAATITENAAA
ACARLGIPHLIVRRPPWPAGDATVVSSAAEAKDAVVAQGFSRVFLTSGRSSVGAFLFSDAWFLIRVVEPMSADELPERHH
LLLSRGPYTVAEETELMRQYEIEVLVTKNSGGTMTSAKLEAAAALGIPVVMIDRPALPENVSTVSTVDAAQQWVTERDNA
GV

Sequences:

>Translated_242_residues
MILGGSAEARELAERLAPRFDVTTSLAGRVNNPAVPAGALRIGGFGGEVGLRKWLLDNAIDAVVDATHPFAATITENAAA
ACARLGIPHLIVRRPPWPAGDATVVSSAAEAKDAVVAQGFSRVFLTSGRSSVGAFLFSDAWFLIRVVEPMSADELPERHH
LLLSRGPYTVAEETELMRQYEIEVLVTKNSGGTMTSAKLEAAAALGIPVVMIDRPALPENVSTVSTVDAAQQWVTERDNA
GV
>Mature_242_residues
MILGGSAEARELAERLAPRFDVTTSLAGRVNNPAVPAGALRIGGFGGEVGLRKWLLDNAIDAVVDATHPFAATITENAAA
ACARLGIPHLIVRRPPWPAGDATVVSSAAEAKDAVVAQGFSRVFLTSGRSSVGAFLFSDAWFLIRVVEPMSADELPERHH
LLLSRGPYTVAEETELMRQYEIEVLVTKNSGGTMTSAKLEAAAALGIPVVMIDRPALPENVSTVSTVDAAQQWVTERDNA
GV

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 25581; Mature: 25581

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGGSAEARELAERLAPRFDVTTSLAGRVNNPAVPAGALRIGGFGGEVGLRKWLLDNAI
CEECCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHH
DAVVDATHPFAATITENAAAACARLGIPHLIVRRPPWPAGDATVVSSAAEAKDAVVAQGF
HHHHCCCCCCEEEHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
SRVFLTSGRSSVGAFLFSDAWFLIRVVEPMSADELPERHHLLLSRGPYTVAEETELMRQY
HHEEEECCCCHHHHHHHHHHEEEEEEECCCCCCCCCCHHHEEEECCCCCHHHHHHHHHHE
EIEVLVTKNSGGTMTSAKLEAAAALGIPVVMIDRPALPENVSTVSTVDAAQQWVTERDNA
EEEEEEEECCCCCEEHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCC
GV
CC
>Mature Secondary Structure
MILGGSAEARELAERLAPRFDVTTSLAGRVNNPAVPAGALRIGGFGGEVGLRKWLLDNAI
CEECCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHH
DAVVDATHPFAATITENAAAACARLGIPHLIVRRPPWPAGDATVVSSAAEAKDAVVAQGF
HHHHCCCCCCEEEHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCC
SRVFLTSGRSSVGAFLFSDAWFLIRVVEPMSADELPERHHLLLSRGPYTVAEETELMRQY
HHEEEECCCCHHHHHHHHHHEEEEEEECCCCCCCCCCHHHEEEECCCCCHHHHHHHHHHE
EIEVLVTKNSGGTMTSAKLEAAAALGIPVVMIDRPALPENVSTVSTVDAAQQWVTERDNA
EEEEEEEECCCCCEEHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCC
GV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]