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The map label for this gene is cobM [H]

Identifier: 169629282

GI number: 169629282

Start: 2210988

End: 2211788

Strand: Direct

Name: cobM [H]

Synonym: MAB_2196

Alternate gene names: 169629282

Gene position: 2210988-2211788 (Clockwise)

Preceding gene: 169629281

Following gene: 169629283

Centisome position: 43.63

GC content: 63.8

Gene sequence:

>801_bases
TTGGAGATCTCGTCTGCCCGTAGTTCAGTGGAGCACCGAAAAATCATGACCGTCTATTTCATCGGTGCCGGACCGGGCGC
GGCCGACCTCATCACGGTGCGTGGACAGCGGATCCTGCGGCAGTGCTCTGTGTGTCTGTATGCGGGATCGATCATGCCGG
ATGACCTGTTGGCGGAGTGCCCACCGGGAGCTCGCGTTGTCGACACCGGTCCGCTGACCCTGGACGCCATCATCGAGGAG
ATATCCGCGGCCGATGCGGAAGGATTAGATGTTGCCCGACTGCATTCCGGTGATCCTTCCCTCTACAGTGCGGTCGCCGA
ACAGTGTCGGCGGCTCGACGTGCTGGGTATCGATCATGAAATCGTGCCGGGTGTGCCGGCTTTCGCGGCAGCCGCTGCGG
CGCTGGGTACCGAACTCACCGTTCCGGGCGTCGCGCAGACGGTCACGATCACCCGCGTTTCGACGTTGTCCACCGCGATG
CCCGAGGGTGAGGATCTGCGCACGCTGGCCGCACCCGGGGCAACACTGGCATTGCACCTGGCGGCGGCCCAGATCGATAC
CGTGGCTGCCGATCTCGTCGCCGGGGGATATCCGTCCGATACTCCGGTCGCCGTGGTGGCCTACGCCAGCTGGCCCTCCG
AGACGATCCTGCGTGGCACCCTTGCCGACATAGCCGGGCAGCTGAAGGAGGCGGCTGTCACCAAGACTGCGGTCATTTTC
GTAGGCAAGGTGCTTGCGGCAGAGGGGTTTACCGATAGCTATCTGTATTCCTCGGGACGTCGGAGAGGGGCTTCGCACTG
A

Upstream 100 bases:

>100_bases
CGGAATCCGAAGCGTTGTTGCTGCGATGGTATTGCCGCTATGGGGGAGAGTTGCGCAGGTATCGTGTCGAAGACGCCGCC
CCGCTCGGAGGCTTCACCAG

Downstream 100 bases:

>100_bases
TGCCAGCACTAAGGAGAGTCTTGATCCTCGGGGGCTCGGCGGAAGCACGCGAGTTGGCCGAGCGGCTAGCACCCCGATTC
GACGTCACCACCTCCCTCGC

Product: precorrin-4 C11-methyltransferase CobM

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MEISSARSSVEHRKIMTVYFIGAGPGAADLITVRGQRILRQCSVCLYAGSIMPDDLLAECPPGARVVDTGPLTLDAIIEE
ISAADAEGLDVARLHSGDPSLYSAVAEQCRRLDVLGIDHEIVPGVPAFAAAAAALGTELTVPGVAQTVTITRVSTLSTAM
PEGEDLRTLAAPGATLALHLAAAQIDTVAADLVAGGYPSDTPVAVVAYASWPSETILRGTLADIAGQLKEAAVTKTAVIF
VGKVLAAEGFTDSYLYSSGRRRGASH

Sequences:

>Translated_266_residues
MEISSARSSVEHRKIMTVYFIGAGPGAADLITVRGQRILRQCSVCLYAGSIMPDDLLAECPPGARVVDTGPLTLDAIIEE
ISAADAEGLDVARLHSGDPSLYSAVAEQCRRLDVLGIDHEIVPGVPAFAAAAAALGTELTVPGVAQTVTITRVSTLSTAM
PEGEDLRTLAAPGATLALHLAAAQIDTVAADLVAGGYPSDTPVAVVAYASWPSETILRGTLADIAGQLKEAAVTKTAVIF
VGKVLAAEGFTDSYLYSSGRRRGASH
>Mature_266_residues
MEISSARSSVEHRKIMTVYFIGAGPGAADLITVRGQRILRQCSVCLYAGSIMPDDLLAECPPGARVVDTGPLTLDAIIEE
ISAADAEGLDVARLHSGDPSLYSAVAEQCRRLDVLGIDHEIVPGVPAFAAAAAALGTELTVPGVAQTVTITRVSTLSTAM
PEGEDLRTLAAPGATLALHLAAAQIDTVAADLVAGGYPSDTPVAVVAYASWPSETILRGTLADIAGQLKEAAVTKTAVIF
VGKVLAAEGFTDSYLYSSGRRRGASH

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=257, Percent_Identity=28.4046692607004, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 27440; Mature: 27440

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00839 SUMT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEISSARSSVEHRKIMTVYFIGAGPGAADLITVRGQRILRQCSVCLYAGSIMPDDLLAEC
CCCCHHHHHHHHEEEEEEEEEECCCCCHHEEEHHHHHHHHHHHHHHHCCCCCCHHHHHCC
PPGARVVDTGPLTLDAIIEEISAADAEGLDVARLHSGDPSLYSAVAEQCRRLDVLGIDHE
CCCCEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCH
IVPGVPAFAAAAAALGTELTVPGVAQTVTITRVSTLSTAMPEGEDLRTLAAPGATLALHL
HCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHHHCCCCCCCCHHHHCCCCHHHHHH
AAAQIDTVAADLVAGGYPSDTPVAVVAYASWPSETILRGTLADIAGQLKEAAVTKTAVIF
HHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGKVLAAEGFTDSYLYSSGRRRGASH
HHHHHHHCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEISSARSSVEHRKIMTVYFIGAGPGAADLITVRGQRILRQCSVCLYAGSIMPDDLLAEC
CCCCHHHHHHHHEEEEEEEEEECCCCCHHEEEHHHHHHHHHHHHHHHCCCCCCHHHHHCC
PPGARVVDTGPLTLDAIIEEISAADAEGLDVARLHSGDPSLYSAVAEQCRRLDVLGIDHE
CCCCEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCH
IVPGVPAFAAAAAALGTELTVPGVAQTVTITRVSTLSTAMPEGEDLRTLAAPGATLALHL
HCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHHHCCCCCCCCHHHHCCCCHHHHHH
AAAQIDTVAADLVAGGYPSDTPVAVVAYASWPSETILRGTLADIAGQLKEAAVTKTAVIF
HHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGKVLAAEGFTDSYLYSSGRRRGASH
HHHHHHHCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]