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The map label for this gene is prcA

Identifier: 169629259

GI number: 169629259

Start: 2187544

End: 2188326

Strand: Direct

Name: prcA

Synonym: MAB_2173

Alternate gene names: 169629259

Gene position: 2187544-2188326 (Clockwise)

Preceding gene: 169629258

Following gene: 169629260

Centisome position: 43.17

GC content: 65.39

Gene sequence:

>783_bases
ATGACCTTTCCGTACTACGCCTCGGTCGAGCAGCTCATGCGCGACCGTTCGGAATTGGCGCGCAAGGGCATCAGCCGGGG
CCGTTCGGTAGTGGCACTGACCTATACCGACGGGGTGTTGTTCGTCGCCGAGAACCCATCGAACTCGCTGCAGAAAGTCA
GTGAGGTCTATGACCGGGTGGGCTTCGCCGCGGTCGGAAAGTTCAATGAGTTCGACCGGCTGCGCCGCGGTGGTATTCAG
TGGGCCGATATGCGTGGCTACGCGTACGACCGCCGCGATGTGAGCGGGCGGCAACTGGCCAACATCTATGCCGAGGCATT
GGGCACCATTTTCAACGAGCAGGCCAAGCCCTACGAGGTCGAGCTGTGCGTCGGCGAGGTGGCCCACTATGGTCGCGACA
CCGAGCCGGTGCTGTACCGGATCACCTATGACGGGTCGATCGCCGACGAGCCGCACTGGGTGGTGATGGGCGGAAACACC
GAGCCCGTGATCAACTCGCTCAAGGAGAGCTACGTCGAGGACTCCGCGCTCAAGGATGCGGTGGGTTTCGCGGTGAAGGC
ACTGCAGGCGGGGACAGCCGGCGCCAACGGCTCCGAGGGCAGGGCGCTGGGCGGACTCGAGGTCGCGGTACTGGAGCAGA
GTCGTCCGCGCCGGGCCTTCCGGCGGATCAAGGGCGCCGCGCTGGAAGCGCTGTTGCCCGAGGATTTCTCGCCGGGACAG
ACCGAGGGCGGGGGCGACCCCGCACCGGAATCCGGCGATTCCAAGGACGCCAAGGACAACTAG

Upstream 100 bases:

>100_bases
TCCCCGAGGCCGATATCGAGAGGATCGCGCGCGAAGTCATCGCGAAGCGGACCGAGGCGGCACGGGAAGAAGCTGACTTG
CGTGAATCGGGTGGTGACTC

Downstream 100 bases:

>100_bases
CTCTTTCACACGCCGACACCAACGCGCTAGTCACCGGGCACTTATCCACAGCCTGAAAAATGACGGAACCGCCGGGGTAT
ACCGGCGGTCCTACCTGCTA

Product: proteasome (alpha subunit) PrcA

Products: NA

Alternate protein names: 20S proteasome alpha subunit; Proteasome core protein PrcA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MTFPYYASVEQLMRDRSELARKGISRGRSVVALTYTDGVLFVAENPSNSLQKVSEVYDRVGFAAVGKFNEFDRLRRGGIQ
WADMRGYAYDRRDVSGRQLANIYAEALGTIFNEQAKPYEVELCVGEVAHYGRDTEPVLYRITYDGSIADEPHWVVMGGNT
EPVINSLKESYVEDSALKDAVGFAVKALQAGTAGANGSEGRALGGLEVAVLEQSRPRRAFRRIKGAALEALLPEDFSPGQ
TEGGGDPAPESGDSKDAKDN

Sequences:

>Translated_260_residues
MTFPYYASVEQLMRDRSELARKGISRGRSVVALTYTDGVLFVAENPSNSLQKVSEVYDRVGFAAVGKFNEFDRLRRGGIQ
WADMRGYAYDRRDVSGRQLANIYAEALGTIFNEQAKPYEVELCVGEVAHYGRDTEPVLYRITYDGSIADEPHWVVMGGNT
EPVINSLKESYVEDSALKDAVGFAVKALQAGTAGANGSEGRALGGLEVAVLEQSRPRRAFRRIKGAALEALLPEDFSPGQ
TEGGGDPAPESGDSKDAKDN
>Mature_259_residues
TFPYYASVEQLMRDRSELARKGISRGRSVVALTYTDGVLFVAENPSNSLQKVSEVYDRVGFAAVGKFNEFDRLRRGGIQW
ADMRGYAYDRRDVSGRQLANIYAEALGTIFNEQAKPYEVELCVGEVAHYGRDTEPVLYRITYDGSIADEPHWVVMGGNTE
PVINSLKESYVEDSALKDAVGFAVKALQAGTAGANGSEGRALGGLEVAVLEQSRPRRAFRRIKGAALEALLPEDFSPGQT
EGGGDPAPESGDSKDAKDN

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1A family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PSA_MYCA9 (B1MAI3)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001702908.1
- ProteinModelPortal:   B1MAI3
- SMR:   B1MAI3
- EnsemblBacteria:   EBMYCT00000008897
- GeneID:   5964686
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_2173
- GeneTree:   EBGT00050000016603
- HOGENOM:   HBG292323
- OMA:   AVGKYNE
- ProtClustDB:   CLSK872007
- BioCyc:   MABS561007:MAB_2173-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00289_B
- InterPro:   IPR022296
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03691

Pfam domain/function: PF00227 Proteasome

EC number: =3.4.25.1

Molecular weight: Translated: 28340; Mature: 28209

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00388 PROTEASOME_A_1; PS51475 PROTEASOME_A_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFPYYASVEQLMRDRSELARKGISRGRSVVALTYTDGVLFVAENPSNSLQKVSEVYDRV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCEEEEEECCCHHHHHHHHHHHHH
GFAAVGKFNEFDRLRRGGIQWADMRGYAYDRRDVSGRQLANIYAEALGTIFNEQAKPYEV
CHHHHCCCHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
ELCVGEVAHYGRDTEPVLYRITYDGSIADEPHWVVMGGNTEPVINSLKESYVEDSALKDA
EHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
VGFAVKALQAGTAGANGSEGRALGGLEVAVLEQSRPRRAFRRIKGAALEALLPEDFSPGQ
HHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC
TEGGGDPAPESGDSKDAKDN
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TFPYYASVEQLMRDRSELARKGISRGRSVVALTYTDGVLFVAENPSNSLQKVSEVYDRV
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCEEEEEECCCHHHHHHHHHHHHH
GFAAVGKFNEFDRLRRGGIQWADMRGYAYDRRDVSGRQLANIYAEALGTIFNEQAKPYEV
CHHHHCCCHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
ELCVGEVAHYGRDTEPVLYRITYDGSIADEPHWVVMGGNTEPVINSLKESYVEDSALKDA
EHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
VGFAVKALQAGTAGANGSEGRALGGLEVAVLEQSRPRRAFRRIKGAALEALLPEDFSPGQ
HHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC
TEGGGDPAPESGDSKDAKDN
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA