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The map label for this gene is sigK [H]

Identifier: 169629249

GI number: 169629249

Start: 2178058

End: 2178540

Strand: Direct

Name: sigK [H]

Synonym: MAB_2163

Alternate gene names: 169629249

Gene position: 2178058-2178540 (Clockwise)

Preceding gene: 169629248

Following gene: 169629250

Centisome position: 42.98

GC content: 65.84

Gene sequence:

>483_bases
ATGAGGGCCTTTTACGACGAGTACGCCGGCCCGTTGCACCGTTATGTCATGCATCTGACCCACGACTCGGCGCTCGCGGA
AGACATCGTGCAGGAGGTGCTGCTGCGCGCCTGGCGCCATCCGACGCTGGTGAATCAGACCGAAGGATCAGCGCGGGCCT
GGTTGTTCACGGTGGCCCACAATCTGGTCCGCGACAACGCGCGCAGCTCGCGCTTCCGCAGCGAGATAGCGACCGCCGAG
ACGCCCGAGTTCGCCTCCCCGGATCAGGTGGACGCCACGTTGGACGCATGGCTGGTCGCCGAGGCGCTGCGCACCTTGTC
CACCGACCATCGCGCCGTCATCCTGCGCGCCTACTACCGCGGGAGCTCGGTCGCCGACATATCCGCTGAGCTGGGGGTGC
CGGAGGGCACCGTCAAATCACGCCTTCACTATGGTGTGCGCGCACTTCGGTTGTCGCTGCAGGAAATGGGGGTCACGCGA
TGA

Upstream 100 bases:

>100_bases
CGATGATGCGCGTGCAAGCGGCTCATCCCAACCCGACACTCTTCGCGCAAGCGGCTCATCCCAACCCGACACTCTTCGCG
CAAGCGGCTCATCGTCGCTG

Downstream 100 bases:

>100_bases
CTATCGAACATGTCTATGCCGACTGGGACGCCGCGTATGTACTCGGCGCGTTGTCGTCGACCGAACGGCGTGAATACGAG
CAGCATCTGGTCGATTGCGT

Product: ECF subfamily RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-K factor [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MRAFYDEYAGPLHRYVMHLTHDSALAEDIVQEVLLRAWRHPTLVNQTEGSARAWLFTVAHNLVRDNARSSRFRSEIATAE
TPEFASPDQVDATLDAWLVAEALRTLSTDHRAVILRAYYRGSSVADISAELGVPEGTVKSRLHYGVRALRLSLQEMGVTR

Sequences:

>Translated_160_residues
MRAFYDEYAGPLHRYVMHLTHDSALAEDIVQEVLLRAWRHPTLVNQTEGSARAWLFTVAHNLVRDNARSSRFRSEIATAE
TPEFASPDQVDATLDAWLVAEALRTLSTDHRAVILRAYYRGSSVADISAELGVPEGTVKSRLHYGVRALRLSLQEMGVTR
>Mature_160_residues
MRAFYDEYAGPLHRYVMHLTHDSALAEDIVQEVLLRAWRHPTLVNQTEGSARAWLFTVAHNLVRDNARSSRFRSEIATAE
TPEFASPDQVDATLDAWLVAEALRTLSTDHRAVILRAYYRGSSVADISAELGVPEGTVKSRLHYGVRALRLSLQEMGVTR

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR007627
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 18004; Mature: 18004

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFYDEYAGPLHRYVMHLTHDSALAEDIVQEVLLRAWRHPTLVNQTEGSARAWLFTVAH
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
NLVRDNARSSRFRSEIATAETPEFASPDQVDATLDAWLVAEALRTLSTDHRAVILRAYYR
HHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEHHHHHC
GSSVADISAELGVPEGTVKSRLHYGVRALRLSLQEMGVTR
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRAFYDEYAGPLHRYVMHLTHDSALAEDIVQEVLLRAWRHPTLVNQTEGSARAWLFTVAH
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
NLVRDNARSSRFRSEIATAETPEFASPDQVDATLDAWLVAEALRTLSTDHRAVILRAYYR
HHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHEEHHHHHC
GSSVADISAELGVPEGTVKSRLHYGVRALRLSLQEMGVTR
CCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]