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The map label for this gene is nuoG [H]

Identifier: 169629226

GI number: 169629226

Start: 2151128

End: 2153506

Strand: Direct

Name: nuoG [H]

Synonym: MAB_2140

Alternate gene names: 169629226

Gene position: 2151128-2153506 (Clockwise)

Preceding gene: 169629225

Following gene: 169629227

Centisome position: 42.45

GC content: 66.83

Gene sequence:

>2379_bases
ATGACCGCGGTACAGCCAGACACCGATCTGGTCACCGTCAACATCGACGGAACCGATATCTCGGTTCCCAAGGGCACCCT
GGTCATCCGTGCCGCCGAACTCATCGGTGTGCAGATTCCCAGGTTCTGCGATCACCCGTTGCTCGATCCCGTCGGCGCGT
GCCGTCAATGCCTCGTGGAGGTGGAGGGGCAGCGTAAGCCGTTGGCGGCATGTACCACCACCGTCGCCGACGAGATGGTG
GTGCGCACACAGATCACCTCTGCGGCCGCGCAGCGGGCGCAGAGCGGCGTGATGGAATTGCTGCTGATCAATCACCCTTT
GGATTGTCCTGTTTGCGACAAGGGCGGAGAGTGCCCGCTGCAGAACCAGGCGATGTCCACCGGTCGCGCTGAAACCCGGT
TCACCGAGGCCAAACGCACTTTCCCTAAGCCGATTCCGCTGTCCACCGAGGTGCTGCTGGACAGGGAGCGATGTGTGCTG
TGCGCGCGCTGCACCCGGTTTTCCCAACAAGTCGCCGGTGATCCGTTCATCGAGCTGCTGGAACGTGGTGCGCTGCAACA
GGTTGGCATCGCCAGCGATGAGCCCTTCCAGTCGTACTTCTCCGGCAATACCGTGCAGATCTGCCCCGTAGGTGCGCTTA
CCGGCGCTGCGTACAGATTTCGGGCCCGCCCGTTTGATTTGGTTTCCACGCCGAGCGTGTGTGAGCACTGTGCCAGCGGA
TGCGCACAGCGCACCGACCATCGGCGGGGCAAGGTGCTACGGCGCCTGGCCGGTGACGATCCCGAGGTCAACGAAGAATG
GAACTGCGATAAGGGACGCTGGGCGTTCACCTATGCCACGGCGGGCGACCGCATCACCGAACCGATGGTCCGCGACGAGC
ACGGAAAGCTCGTGGCGGTGTCGTGGCCGCAGGCGCTTGACGCCGCGGCGCGGGGCTTGGCGCATGCGGGAGCCAACACC
GGGGTGCTTGCCGGCGGACGGCTGACGGTCGAAGATGCCTACGCCTACGTCAAGTTCGCACGCATGGTGTTGGGCACCAA
CAACATCGACTTCCGGGCTCGCGCGCACAGCATGGAAGAGGCGGCCTTCCTCGGTTCGGTGGTCGCCGGTCGAGGGATGT
CCCAGACCTATGCGGCGTTGGAGTCGGCGCCGGCGGTCTTGCTGGCGGGATTCGAGCCGGAGGAGGAATCGCCCGTCGTC
TTCCTGCGGCTGCGTAAGGGAGTGCGCAAGCGGGGGCTCAAGGTGCTCACCATCGCGCCTTGGGTGAGTCGTGGATCTAC
CAAGCTATCTGCCGAGGTGCTTGTCGTGGCCCCCGGAACAGAGCCGGAAACCATTGCGGGTCTTGCGGGTTCTGAGCTGC
TGCGGCAGCCGGGAGCGGTGATCATGGTGGGGGAGCGGCTCGCGTCGGCGCCGGGCGCGTTGTCGGCGGCAGCGCAGCTG
GCCGACAAGACGGGCGCCGCCTTGGTGTGGGTTCCGCGCCGGGCGGGCGAGCGCGGGGCCTTGGAGGCCGGGGCACTGCC
GCGCCTGCTGCCGGGCGCACATCCGGTAGCGGACAGCACGGCACGTCGCGCTATCGCCGAGAAATGGGGAGTAATCGCAT
TGCCCGACAAGCCCGGGCTGGATGCCGCCGGCATGCTGGACCCGGGAAGCGGTCTCGATGCCTTCCTTGTCGGCGGGGTC
GAACTGGCCGATCTGCCGTATCCCGCCGCTGCCATAGGCGCTCTCAAGACGGCATTCGTGGTGAGCCTGGAGATGCGCCA
TGGGGCCGTCACCGAACTCGCCGATGTCGTGCTCCCGATCGCGGCCGTCGCGGAGAAGTCCGGCAGTTTCCTGAACTGGG
AAGGCCGGCTGCGCCCGTTCCGCACCACCCTGGAGACCAGCGATGCCTTGGACGACCTCCGGGTGCTTGCCGCGCTTTCA
CAGCGGATGGATCGCCCGATTGGCCTGAACCACGCGAACCAGGCGCTTGCCGAGCTCGCGGACATCGGTCCGTGGGAAGG
AGCACGGGAAACGCCGGGCGCGGTGCGTGCCGCCGGCAGGCCGCAGCCCGAAGCGGGAGAGGCGGTATTGGCCTCGTGGC
GGCTCCTGCTCGATATCGGCCGGCTGCAGGACGGCGAGCCGTACCTCGCCGGGACGGCACACGAGGCCCAGGTCCTGCTG
TCCGAGGCGACGGCCAACGAAATCGGGGCGGCCGAAGGTGAATCGGTGACCGTACGCAGCCTGTCGGAATCGATCCGGGG
CGCAATTACCCTGCCGCTGAGGATAACCGAGATGCCGGACCGGGTGGTCTGGGTGCCCATGCGCTCGACGGGGTCGGAGC
TTCATCAGCAACTTGGCCCGGCGCTCGGCCAAGTGGTGAGAATCGAGGTGGCCCCGTGA

Upstream 100 bases:

>100_bases
TGTCCTCCCTGAAATACTTCCGCACCGAATACGAGGCCCACCTGGACAACGGGTGCCCCTTTGATCCGGCGGCCAGCACC
GTATTCGGGGAGGTGTCCGC

Downstream 100 bases:

>100_bases
CCGGCAGGACCGACCTTTCACAATTCGGGATCGACCCGTTATGGCTGGTCCTTGTGAAATGCGTGGCGGTATTCGCCTTT
CTGGTTCTCACTGTGCTCAT

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 792; Mature: 791

Protein sequence:

>792_residues
MTAVQPDTDLVTVNIDGTDISVPKGTLVIRAAELIGVQIPRFCDHPLLDPVGACRQCLVEVEGQRKPLAACTTTVADEMV
VRTQITSAAAQRAQSGVMELLLINHPLDCPVCDKGGECPLQNQAMSTGRAETRFTEAKRTFPKPIPLSTEVLLDRERCVL
CARCTRFSQQVAGDPFIELLERGALQQVGIASDEPFQSYFSGNTVQICPVGALTGAAYRFRARPFDLVSTPSVCEHCASG
CAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFTYATAGDRITEPMVRDEHGKLVAVSWPQALDAAARGLAHAGANT
GVLAGGRLTVEDAYAYVKFARMVLGTNNIDFRARAHSMEEAAFLGSVVAGRGMSQTYAALESAPAVLLAGFEPEEESPVV
FLRLRKGVRKRGLKVLTIAPWVSRGSTKLSAEVLVVAPGTEPETIAGLAGSELLRQPGAVIMVGERLASAPGALSAAAQL
ADKTGAALVWVPRRAGERGALEAGALPRLLPGAHPVADSTARRAIAEKWGVIALPDKPGLDAAGMLDPGSGLDAFLVGGV
ELADLPYPAAAIGALKTAFVVSLEMRHGAVTELADVVLPIAAVAEKSGSFLNWEGRLRPFRTTLETSDALDDLRVLAALS
QRMDRPIGLNHANQALAELADIGPWEGARETPGAVRAAGRPQPEAGEAVLASWRLLLDIGRLQDGEPYLAGTAHEAQVLL
SEATANEIGAAEGESVTVRSLSESIRGAITLPLRITEMPDRVVWVPMRSTGSELHQQLGPALGQVVRIEVAP

Sequences:

>Translated_792_residues
MTAVQPDTDLVTVNIDGTDISVPKGTLVIRAAELIGVQIPRFCDHPLLDPVGACRQCLVEVEGQRKPLAACTTTVADEMV
VRTQITSAAAQRAQSGVMELLLINHPLDCPVCDKGGECPLQNQAMSTGRAETRFTEAKRTFPKPIPLSTEVLLDRERCVL
CARCTRFSQQVAGDPFIELLERGALQQVGIASDEPFQSYFSGNTVQICPVGALTGAAYRFRARPFDLVSTPSVCEHCASG
CAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFTYATAGDRITEPMVRDEHGKLVAVSWPQALDAAARGLAHAGANT
GVLAGGRLTVEDAYAYVKFARMVLGTNNIDFRARAHSMEEAAFLGSVVAGRGMSQTYAALESAPAVLLAGFEPEEESPVV
FLRLRKGVRKRGLKVLTIAPWVSRGSTKLSAEVLVVAPGTEPETIAGLAGSELLRQPGAVIMVGERLASAPGALSAAAQL
ADKTGAALVWVPRRAGERGALEAGALPRLLPGAHPVADSTARRAIAEKWGVIALPDKPGLDAAGMLDPGSGLDAFLVGGV
ELADLPYPAAAIGALKTAFVVSLEMRHGAVTELADVVLPIAAVAEKSGSFLNWEGRLRPFRTTLETSDALDDLRVLAALS
QRMDRPIGLNHANQALAELADIGPWEGARETPGAVRAAGRPQPEAGEAVLASWRLLLDIGRLQDGEPYLAGTAHEAQVLL
SEATANEIGAAEGESVTVRSLSESIRGAITLPLRITEMPDRVVWVPMRSTGSELHQQLGPALGQVVRIEVAP
>Mature_791_residues
TAVQPDTDLVTVNIDGTDISVPKGTLVIRAAELIGVQIPRFCDHPLLDPVGACRQCLVEVEGQRKPLAACTTTVADEMVV
RTQITSAAAQRAQSGVMELLLINHPLDCPVCDKGGECPLQNQAMSTGRAETRFTEAKRTFPKPIPLSTEVLLDRERCVLC
ARCTRFSQQVAGDPFIELLERGALQQVGIASDEPFQSYFSGNTVQICPVGALTGAAYRFRARPFDLVSTPSVCEHCASGC
AQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFTYATAGDRITEPMVRDEHGKLVAVSWPQALDAAARGLAHAGANTG
VLAGGRLTVEDAYAYVKFARMVLGTNNIDFRARAHSMEEAAFLGSVVAGRGMSQTYAALESAPAVLLAGFEPEEESPVVF
LRLRKGVRKRGLKVLTIAPWVSRGSTKLSAEVLVVAPGTEPETIAGLAGSELLRQPGAVIMVGERLASAPGALSAAAQLA
DKTGAALVWVPRRAGERGALEAGALPRLLPGAHPVADSTARRAIAEKWGVIALPDKPGLDAAGMLDPGSGLDAFLVGGVE
LADLPYPAAAIGALKTAFVVSLEMRHGAVTELADVVLPIAAVAEKSGSFLNWEGRLRPFRTTLETSDALDDLRVLAALSQ
RMDRPIGLNHANQALAELADIGPWEGARETPGAVRAAGRPQPEAGEAVLASWRLLLDIGRLQDGEPYLAGTAHEAQVLLS
EATANEIGAAEGESVTVRSLSESIRGAITLPLRITEMPDRVVWVPMRSTGSELHQQLGPALGQVVRIEVAP

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton transloca

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=666, Percent_Identity=32.8828828828829, Blast_Score=284, Evalue=3e-76,
Organism=Escherichia coli, GI145693161, Length=412, Percent_Identity=31.5533980582524, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI3868721, Length=512, Percent_Identity=24.8046875, Blast_Score=103, Evalue=6e-23,
Organism=Escherichia coli, GI1788534, Length=222, Percent_Identity=25.2252252252252, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17565758, Length=680, Percent_Identity=32.9411764705882, Blast_Score=269, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI32566231, Length=631, Percent_Identity=34.0729001584786, Blast_Score=264, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI193209088, Length=260, Percent_Identity=43.0769230769231, Blast_Score=196, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24640559, Length=675, Percent_Identity=33.7777777777778, Blast_Score=270, Evalue=4e-72,
Organism=Drosophila melanogaster, GI24640557, Length=675, Percent_Identity=33.7777777777778, Blast_Score=270, Evalue=4e-72,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574 [H]

Pfam domain/function: PF00111 Fer2; PF00384 Molybdopterin; PF01568 Molydop_binding; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 84090; Mature: 83959

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVQPDTDLVTVNIDGTDISVPKGTLVIRAAELIGVQIPRFCDHPLLDPVGACRQCLVE
CCCCCCCCCEEEEEECCCEEECCCCEEEEEEHHHHCCCCCHHCCCCCCCHHHHHHHHHHH
VEGQRKPLAACTTTVADEMVVRTQITSAAAQRAQSGVMELLLINHPLDCPVCDKGGECPL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHEECCCCCCCCCCCCCCCCC
QNQAMSTGRAETRFTEAKRTFPKPIPLSTEVLLDRERCVLCARCTRFSQQVAGDPFIELL
CHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHH
ERGALQQVGIASDEPFQSYFSGNTVQICPVGALTGAAYRFRARPFDLVSTPSVCEHCASG
HCCCHHHCCCCCCCCHHHHHCCCEEEEEECHHHCCCEEEEECCCCCCCCCHHHHHHHHHH
CAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFTYATAGDRITEPMVRDEHGKLVAV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEE
SWPQALDAAARGLAHAGANTGVLAGGRLTVEDAYAYVKFARMVLGTNNIDFRARAHSMEE
ECHHHHHHHHHHHHHCCCCCCEEECCEEEHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHH
AAFLGSVVAGRGMSQTYAALESAPAVLLAGFEPEEESPVVFLRLRKGVRKRGLKVLTIAP
HHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCCCCCCCEEEEHHHHHHHHCCCEEEEEEC
WVSRGSTKLSAEVLVVAPGTEPETIAGLAGSELLRQPGAVIMVGERLASAPGALSAAAQL
CCCCCCCEEEEEEEEECCCCCCHHHHCCCHHHHHHCCCCEEEECHHHCCCCCHHHHHHHH
ADKTGAALVWVPRRAGERGALEAGALPRLLPGAHPVADSTARRAIAEKWGVIALPDKPGL
HHCCCCEEEEEECCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCEEECCCCCCC
DAAGMLDPGSGLDAFLVGGVELADLPYPAAAIGALKTAFVVSLEMRHGAVTELADVVLPI
CCCCCCCCCCCCCEEEECCEEEECCCCCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHH
AAVAEKSGSFLNWEGRLRPFRTTLETSDALDDLRVLAALSQRMDRPIGLNHANQALAELA
HHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
DIGPWEGARETPGAVRAAGRPQPEAGEAVLASWRLLLDIGRLQDGEPYLAGTAHEAQVLL
HCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHH
SEATANEIGAAEGESVTVRSLSESIRGAITLPLRITEMPDRVVWVPMRSTGSELHQQLGP
HHHHHHHCCCCCCCCEEHHHHHHHHCCEEEEEEEEECCCCCEEEEECCCCHHHHHHHHCH
ALGQVVRIEVAP
HHCCEEEEEECC
>Mature Secondary Structure 
TAVQPDTDLVTVNIDGTDISVPKGTLVIRAAELIGVQIPRFCDHPLLDPVGACRQCLVE
CCCCCCCCEEEEEECCCEEECCCCEEEEEEHHHHCCCCCHHCCCCCCCHHHHHHHHHHH
VEGQRKPLAACTTTVADEMVVRTQITSAAAQRAQSGVMELLLINHPLDCPVCDKGGECPL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHEECCCCCCCCCCCCCCCCC
QNQAMSTGRAETRFTEAKRTFPKPIPLSTEVLLDRERCVLCARCTRFSQQVAGDPFIELL
CHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHH
ERGALQQVGIASDEPFQSYFSGNTVQICPVGALTGAAYRFRARPFDLVSTPSVCEHCASG
HCCCHHHCCCCCCCCHHHHHCCCEEEEEECHHHCCCEEEEECCCCCCCCCHHHHHHHHHH
CAQRTDHRRGKVLRRLAGDDPEVNEEWNCDKGRWAFTYATAGDRITEPMVRDEHGKLVAV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEE
SWPQALDAAARGLAHAGANTGVLAGGRLTVEDAYAYVKFARMVLGTNNIDFRARAHSMEE
ECHHHHHHHHHHHHHCCCCCCEEECCEEEHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHH
AAFLGSVVAGRGMSQTYAALESAPAVLLAGFEPEEESPVVFLRLRKGVRKRGLKVLTIAP
HHHHHHHHHCCCCHHHHHHHHCCCEEEEECCCCCCCCCEEEEHHHHHHHHCCCEEEEEEC
WVSRGSTKLSAEVLVVAPGTEPETIAGLAGSELLRQPGAVIMVGERLASAPGALSAAAQL
CCCCCCCEEEEEEEEECCCCCCHHHHCCCHHHHHHCCCCEEEECHHHCCCCCHHHHHHHH
ADKTGAALVWVPRRAGERGALEAGALPRLLPGAHPVADSTARRAIAEKWGVIALPDKPGL
HHCCCCEEEEEECCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCEEECCCCCCC
DAAGMLDPGSGLDAFLVGGVELADLPYPAAAIGALKTAFVVSLEMRHGAVTELADVVLPI
CCCCCCCCCCCCCEEEECCEEEECCCCCHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHH
AAVAEKSGSFLNWEGRLRPFRTTLETSDALDDLRVLAALSQRMDRPIGLNHANQALAELA
HHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
DIGPWEGARETPGAVRAAGRPQPEAGEAVLASWRLLLDIGRLQDGEPYLAGTAHEAQVLL
HCCCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHH
SEATANEIGAAEGESVTVRSLSESIRGAITLPLRITEMPDRVVWVPMRSTGSELHQQLGP
HHHHHHHCCCCCCCCEEHHHHHHHHCCEEEEEEEEECCCCCEEEEECCCCHHHHHHHHCH
ALGQVVRIEVAP
HHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]