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The map label for this gene is nuoC

Identifier: 169629222

GI number: 169629222

Start: 2147106

End: 2147792

Strand: Direct

Name: nuoC

Synonym: MAB_2136

Alternate gene names: 169629222

Gene position: 2147106-2147792 (Clockwise)

Preceding gene: 169629221

Following gene: 169629223

Centisome position: 42.37

GC content: 59.53

Gene sequence:

>687_bases
GTGACCGGCGGCGAGCAGAAACCGAATGAAATAATCGGGGTGCGGCGCGGGCTCTTTGGGGTGCGGGGGAGCGGCGACAC
ATCCGGCTACGGCGGTCTAGTCCAACCGATTTCCTTGCCGGTTAGCTCGAACCGTCCGTACGGCGGGTACTTCGACCAGG
TGGTCGACAGGCTGGAATCGGTTCTCGCAGAGCAGGAGAACGTTACCTACGCGGATGCTGTCGAAGGTGTGGTCGTGTAT
CGCGATCAACTGACCATTCACGTGAAAGCCGAGCATCTGGTTCAGGTCGCCCAATCGCTGCGCGATGATCCGCAACTGCG
CTTCGAGCTCAGTCTCGGTGTGAGCGGGGTGCACTATCCCGATGACTCTGCGCGGGAATTGCATGCCGTTTACCCGCTCA
TGTCCATCACCTGGAATCGCCGGATCATGCTGGAAGTAGCTGTACCGGAAAGCGATCCGCACATCCCTTCGCTCAATGCC
GTCTACCCGACCACGGATTGGCATGAACGCGAAACCTACGACTTCTTCGGAATCATCTTTGATGATCATCCCGCACTGAC
GCGCATACAGATGCCCGACGACTGGGACGGGCACCCGCAGCGCAAGGACTACCCGCTGGGTGGTGTGCCGGTCGAGTATC
ACGGAGCAACCATTGCACCGCCCGATCAGCGGAGGTCTTACAACTAA

Upstream 100 bases:

>100_bases
CGCACATGCCGCTCGGGGCCAATCGCGAGGAAGTCATCCGGGAGACCGAAGCCGCCGCATTGGCCGCGACGCCCACCATC
GAGATGAAGGGACTGCTGCG

Downstream 100 bases:

>100_bases
TGACAGCACAGCCCGAAATCCATCTCATGGCGGGTGGCCAGGACTGGGATGAGATTGTCACCGCCGCAGGGCAAGCCACC
GACGAACGGATCGTCGTCAA

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTGGEQKPNEIIGVRRGLFGVRGSGDTSGYGGLVQPISLPVSSNRPYGGYFDQVVDRLESVLAEQENVTYADAVEGVVVY
RDQLTIHVKAEHLVQVAQSLRDDPQLRFELSLGVSGVHYPDDSARELHAVYPLMSITWNRRIMLEVAVPESDPHIPSLNA
VYPTTDWHERETYDFFGIIFDDHPALTRIQMPDDWDGHPQRKDYPLGGVPVEYHGATIAPPDQRRSYN

Sequences:

>Translated_228_residues
MTGGEQKPNEIIGVRRGLFGVRGSGDTSGYGGLVQPISLPVSSNRPYGGYFDQVVDRLESVLAEQENVTYADAVEGVVVY
RDQLTIHVKAEHLVQVAQSLRDDPQLRFELSLGVSGVHYPDDSARELHAVYPLMSITWNRRIMLEVAVPESDPHIPSLNA
VYPTTDWHERETYDFFGIIFDDHPALTRIQMPDDWDGHPQRKDYPLGGVPVEYHGATIAPPDQRRSYN
>Mature_227_residues
TGGEQKPNEIIGVRRGLFGVRGSGDTSGYGGLVQPISLPVSSNRPYGGYFDQVVDRLESVLAEQENVTYADAVEGVVVYR
DQLTIHVKAEHLVQVAQSLRDDPQLRFELSLGVSGVHYPDDSARELHAVYPLMSITWNRRIMLEVAVPESDPHIPSLNAV
YPTTDWHERETYDFFGIIFDDHPALTRIQMPDDWDGHPQRKDYPLGGVPVEYHGATIAPPDQRRSYN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=127, Percent_Identity=33.8582677165354, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI145693162, Length=126, Percent_Identity=42.8571428571429, Blast_Score=104, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71990788, Length=127, Percent_Identity=34.6456692913386, Blast_Score=78, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32563621, Length=127, Percent_Identity=34.6456692913386, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24656494, Length=127, Percent_Identity=36.2204724409449, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_MYCA9 (B1MPG6)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001702871.1
- ProteinModelPortal:   B1MPG6
- SMR:   B1MPG6
- EnsemblBacteria:   EBMYCT00000006540
- GeneID:   5964649
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_2136
- GeneTree:   EBGT00050000017747
- HOGENOM:   HBG727675
- OMA:   VYPTNDW
- ProtClustDB:   PRK07785
- BioCyc:   MABS561007:MAB_2136-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 25570; Mature: 25439

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGGEQKPNEIIGVRRGLFGVRGSGDTSGYGGLVQPISLPVSSNRPYGGYFDQVVDRLES
CCCCCCCCHHHHHHHHCEEECCCCCCCCCCCCEECEEEEECCCCCCCCCHHHHHHHHHHH
VLAEQENVTYADAVEGVVVYRDQLTIHVKAEHLVQVAQSLRDDPQLRFELSLGVSGVHYP
HHHHCCCCCHHHHHCCEEEEEEEEEEEECHHHHHHHHHHHCCCCCEEEEEEECCCEEECC
DDSARELHAVYPLMSITWNRRIMLEVAVPESDPHIPSLNAVYPTTDWHERETYDFFGIIF
CCCHHHHHHHHHHHHEEECCEEEEEEECCCCCCCCCCCCEECCCCCCCCCCCEEEEEEEE
DDHPALTRIQMPDDWDGHPQRKDYPLGGVPVEYHGATIAPPDQRRSYN
CCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGGEQKPNEIIGVRRGLFGVRGSGDTSGYGGLVQPISLPVSSNRPYGGYFDQVVDRLES
CCCCCCCHHHHHHHHCEEECCCCCCCCCCCCEECEEEEECCCCCCCCCHHHHHHHHHHH
VLAEQENVTYADAVEGVVVYRDQLTIHVKAEHLVQVAQSLRDDPQLRFELSLGVSGVHYP
HHHHCCCCCHHHHHCCEEEEEEEEEEEECHHHHHHHHHHHCCCCCEEEEEEECCCEEECC
DDSARELHAVYPLMSITWNRRIMLEVAVPESDPHIPSLNAVYPTTDWHERETYDFFGIIF
CCCHHHHHHHHHHHHEEECCEEEEEEECCCCCCCCCCCCEECCCCCCCCCCCEEEEEEEE
DDHPALTRIQMPDDWDGHPQRKDYPLGGVPVEYHGATIAPPDQRRSYN
CCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA