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The map label for this gene is hisE

Identifier: 169629217

GI number: 169629217

Start: 2144264

End: 2144527

Strand: Direct

Name: hisE

Synonym: MAB_2131

Alternate gene names: 169629217

Gene position: 2144264-2144527 (Clockwise)

Preceding gene: 169629216

Following gene: 169629218

Centisome position: 42.32

GC content: 63.64

Gene sequence:

>264_bases
GTGAAGACCTTCGATGAGCTGTTCGCTGAGCTCAGTGATCGCGCCAAGACCCGCCCCGAGGGGAGCGGTACCGTTGCCGC
TCTCGACGCCGGGGTGCACACCCTGGGCAAGAAACTGCTCGAAGAGGCGGGTGAGGTGTGGCTGGCTGCTGAGCACGAGA
GTGACGAATCGCTTGCCGAAGAGGTGAGCCAGTTGCTCTATTGGGCGCAGGTGCTGCTGATCGCGCGCGGCCTCACCCTC
GACGACGTCTACCGAAAGCTCTGA

Upstream 100 bases:

>100_bases
TCCGTGCGCGACCTGCGGGATGCCCACGCCGACGTGCTCGCCGCGACCACCTGCAAACCCATATGACTCGCCGGGCAGGG
TCGTGACAGAATCGCCACCC

Downstream 100 bases:

>100_bases
GATGACCAGTACCAACGGTGCTCTGCGCGTCGCGGTCCCCAACAAGGGGGCGCTCAGTGAAGCCGCATCGGAAATCCTGT
CCGAGGCGGGCTATCGGCGG

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH

Number of amino acids: Translated: 87; Mature: 87

Protein sequence:

>87_residues
MKTFDELFAELSDRAKTRPEGSGTVAALDAGVHTLGKKLLEEAGEVWLAAEHESDESLAEEVSQLLYWAQVLLIARGLTL
DDVYRKL

Sequences:

>Translated_87_residues
MKTFDELFAELSDRAKTRPEGSGTVAALDAGVHTLGKKLLEEAGEVWLAAEHESDESLAEEVSQLLYWAQVLLIARGLTL
DDVYRKL
>Mature_87_residues
MKTFDELFAELSDRAKTRPEGSGTVAALDAGVHTLGKKLLEEAGEVWLAAEHESDESLAEEVSQLLYWAQVLLIARGLTL
DDVYRKL

Specific function: Unknown

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HIS2_MYCA9 (B1MPG1)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001702866.1
- ProteinModelPortal:   B1MPG1
- SMR:   B1MPG1
- EnsemblBacteria:   EBMYCT00000008963
- GeneID:   5964644
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_2131
- GeneTree:   EBGT00050000017721
- HOGENOM:   HBG646527
- OMA:   VWMAAEY
- BioCyc:   MABS561007:MAB_2131-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01020
- InterPro:   IPR008179
- InterPro:   IPR021130
- TIGRFAMs:   TIGR03188

Pfam domain/function: PF01503 PRA-PH

EC number: =3.6.1.31

Molecular weight: Translated: 9617; Mature: 9617

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFDELFAELSDRAKTRPEGSGTVAALDAGVHTLGKKLLEEAGEVWLAAEHESDESLAE
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHH
EVSQLLYWAQVLLIARGLTLDDVYRKL
HHHHHHHHHHHHHHHCCCCHHHHHHHC
>Mature Secondary Structure
MKTFDELFAELSDRAKTRPEGSGTVAALDAGVHTLGKKLLEEAGEVWLAAEHESDESLAE
CCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHH
EVSQLLYWAQVLLIARGLTLDDVYRKL
HHHHHHHHHHHHHHHCCCCHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA