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The map label for this gene is obgE

Identifier: 169628702

GI number: 169628702

Start: 1642155

End: 1643603

Strand: Direct

Name: obgE

Synonym: MAB_1612

Alternate gene names: 169628702

Gene position: 1642155-1643603 (Clockwise)

Preceding gene: 169628701

Following gene: 169628703

Centisome position: 32.41

GC content: 65.84

Gene sequence:

>1449_bases
ATGCCTCGTTTTGTTGATCGCGTTGTCATCCACGCCAAGGCAGGTACCGGCGGTCACGGCTGCGCTTCGGTGCACCGCGA
AAAGTTCAAGCCCCTTGGCGGGCCCGACGGGGGTAACGGCGGACGCGGCGGCAGCGTGATCCTCGAAGTAGACCCGCAGG
TACATACCCTGCTGGACTTCCACTTCCATCCGCACCTACAGGCGCCCAACGGTACCCAGGGCATGGGGGGCCACCGCAAC
GGCGCCAACGGTGATGATCTGATCCTCAAGGTGCCCGACGGTACCGTCGTGCTCGACGATGACGGCCGCATCCTCGCCGA
TTTGGTCGGCGCGGGGGCGCGTTTTGATGCCGCCGCCGGTGGCCGGGGCGGACTGGGCAACGCGGCGTTGGCATCCCGCG
CGCGCAAGGCACCCGGTTTTGCCTTGCTCGGCGAGGCCGGAGCCGAAGTAGACCTCACTCTCGAACTGAAAACTGTCGCC
GATGTGGGGCTGGTCGGTTTTCCCTCGGCAGGGAAATCCTCTCTGGTCTCGGTGCTTTCGGCCGCCAAGCCGAAGATCGC
CGACTATCCGTTCACGACATTGGTGCCCAATCTCGGGGTGGTGACCACGGGCGAGAACTCCTTCGTGATGGCCGATGTGC
CCGGACTTATTCCCGGCGCCGCCGAAGGGCGCGGACTGGGGCTGGAATTTCTGCGCCATATCGAGCGCTGCGCCGTGCTG
GTCCACGTTGTCGACTGTGCGACGCTCGAACCCGGCCGTGACCCGGTCTCCGATATCGACGCACTGGAAAATGAGTTGGC
GCGGTACCAACCCACGTTGCAAGACGACTCCGTGCTCGGCGACCTGGCCGACCGGCCGCGTGCGGTGGTGCTCAACAAGG
TGGACGTACCCGAGGCCGACGAGCTTGCCGACTTTGTCACCGAAGAGGTTTCCCAGCGTGGCTGGCCCGTCTTCAAGGTG
TCCACGCTGACCCGGGACGGACTGCGGCCGTTGACTTTCGCGCTGTGGGAGATGATCGTGGCGGCCCGCGCGGCCCGCCC
CGAACCCGTGAAGACCCGCCCGGTGATTCGGCCCATTCCCGTCGATGAGAGCGGGTTCACCGTTTCTGCGGACCCGCAGA
ATCCGGGTGGCTTTGTGGTGCGTGGTGTGCGCCCCGAGCGCTGGATTCGACAGACCAACTTCGAAAACGACGAAGCCGTG
GGCTATTTGGGCGATCGATTGGCACGTCTGGGTGTCGAAGACGAGCTGCTCAAACTCGGGGCGGAGCCCGGCTGTGCGGT
CACCATCGGCGATATGACATTCGACTGGGAGCCGCAGACGCCGGCGGGTGTCGACGTGACCATGAGCGGACGCGGTACCG
ACGCGCGCATCGACAAGACAGATCGGGTGGGTGCGGCCGAGCGCCGCCAGGCCAGGCGAGTGCGACGTGGGCAGGTGGAG
CCGGAGTGA

Upstream 100 bases:

>100_bases
GGCGTGGTCGCCGGGTCGTCAACATCCTCCCGGTCGACGCTTAATTTGTTGTTCAGTGTCCGGCCTTGACCGAACACTGA
ACAGTTGAAGGAGGCTCCAA

Downstream 100 bases:

>100_bases
ATCCAGGTGCGCAGGCGCGTGAGGCCATTCGCTCGGCGCGCACCGTCGTGGTGAAGGTCGGCACCGCCGCACTCACCGAT
GAGACGGGGACCTTCAGTGC

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MPRFVDRVVIHAKAGTGGHGCASVHREKFKPLGGPDGGNGGRGGSVILEVDPQVHTLLDFHFHPHLQAPNGTQGMGGHRN
GANGDDLILKVPDGTVVLDDDGRILADLVGAGARFDAAAGGRGGLGNAALASRARKAPGFALLGEAGAEVDLTLELKTVA
DVGLVGFPSAGKSSLVSVLSAAKPKIADYPFTTLVPNLGVVTTGENSFVMADVPGLIPGAAEGRGLGLEFLRHIERCAVL
VHVVDCATLEPGRDPVSDIDALENELARYQPTLQDDSVLGDLADRPRAVVLNKVDVPEADELADFVTEEVSQRGWPVFKV
STLTRDGLRPLTFALWEMIVAARAARPEPVKTRPVIRPIPVDESGFTVSADPQNPGGFVVRGVRPERWIRQTNFENDEAV
GYLGDRLARLGVEDELLKLGAEPGCAVTIGDMTFDWEPQTPAGVDVTMSGRGTDARIDKTDRVGAAERRQARRVRRGQVE
PE

Sequences:

>Translated_482_residues
MPRFVDRVVIHAKAGTGGHGCASVHREKFKPLGGPDGGNGGRGGSVILEVDPQVHTLLDFHFHPHLQAPNGTQGMGGHRN
GANGDDLILKVPDGTVVLDDDGRILADLVGAGARFDAAAGGRGGLGNAALASRARKAPGFALLGEAGAEVDLTLELKTVA
DVGLVGFPSAGKSSLVSVLSAAKPKIADYPFTTLVPNLGVVTTGENSFVMADVPGLIPGAAEGRGLGLEFLRHIERCAVL
VHVVDCATLEPGRDPVSDIDALENELARYQPTLQDDSVLGDLADRPRAVVLNKVDVPEADELADFVTEEVSQRGWPVFKV
STLTRDGLRPLTFALWEMIVAARAARPEPVKTRPVIRPIPVDESGFTVSADPQNPGGFVVRGVRPERWIRQTNFENDEAV
GYLGDRLARLGVEDELLKLGAEPGCAVTIGDMTFDWEPQTPAGVDVTMSGRGTDARIDKTDRVGAAERRQARRVRRGQVE
PE
>Mature_481_residues
PRFVDRVVIHAKAGTGGHGCASVHREKFKPLGGPDGGNGGRGGSVILEVDPQVHTLLDFHFHPHLQAPNGTQGMGGHRNG
ANGDDLILKVPDGTVVLDDDGRILADLVGAGARFDAAAGGRGGLGNAALASRARKAPGFALLGEAGAEVDLTLELKTVAD
VGLVGFPSAGKSSLVSVLSAAKPKIADYPFTTLVPNLGVVTTGENSFVMADVPGLIPGAAEGRGLGLEFLRHIERCAVLV
HVVDCATLEPGRDPVSDIDALENELARYQPTLQDDSVLGDLADRPRAVVLNKVDVPEADELADFVTEEVSQRGWPVFKVS
TLTRDGLRPLTFALWEMIVAARAARPEPVKTRPVIRPIPVDESGFTVSADPQNPGGFVVRGVRPERWIRQTNFENDEAVG
YLGDRLARLGVEDELLKLGAEPGCAVTIGDMTFDWEPQTPAGVDVTMSGRGTDARIDKTDRVGAAERRQARRVRRGQVEP
E

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=336, Percent_Identity=42.2619047619048, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI111955139, Length=237, Percent_Identity=37.9746835443038, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI111955063, Length=149, Percent_Identity=39.5973154362416, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI58761500, Length=182, Percent_Identity=27.4725274725275, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4557537, Length=189, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1789574, Length=362, Percent_Identity=42.5414364640884, Blast_Score=228, Evalue=5e-61,
Organism=Escherichia coli, GI1787454, Length=129, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=341, Percent_Identity=38.1231671554252, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17552324, Length=334, Percent_Identity=28.1437125748503, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17509631, Length=134, Percent_Identity=32.089552238806, Blast_Score=75, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321962, Length=203, Percent_Identity=34.4827586206897, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6319281, Length=108, Percent_Identity=38.8888888888889, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321649, Length=138, Percent_Identity=31.8840579710145, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI20129375, Length=320, Percent_Identity=39.0625, Blast_Score=158, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24585318, Length=237, Percent_Identity=37.1308016877637, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24640873, Length=231, Percent_Identity=26.4069264069264, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640877, Length=231, Percent_Identity=26.4069264069264, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640875, Length=231, Percent_Identity=26.4069264069264, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17981711, Length=107, Percent_Identity=36.4485981308411, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_MYCA9 (B1MMY5)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001702351.1
- ProteinModelPortal:   B1MMY5
- SMR:   B1MMY5
- EnsemblBacteria:   EBMYCT00000005264
- GeneID:   5967437
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_1612
- GeneTree:   EBGT00050000015858
- HOGENOM:   HBG716038
- OMA:   PTRQAPN
- ProtClustDB:   PRK12296
- BioCyc:   MABS561007:MAB_1612-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 51100; Mature: 50969

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFVDRVVIHAKAGTGGHGCASVHREKFKPLGGPDGGNGGRGGSVILEVDPQVHTLLDF
CCCHHCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEE
HFHPHLQAPNGTQGMGGHRNGANGDDLILKVPDGTVVLDDDGRILADLVGAGARFDAAAG
ECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHCCCCCCCCCCC
GRGGLGNAALASRARKAPGFALLGEAGAEVDLTLELKTVADVGLVGFPSAGKSSLVSVLS
CCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEHHCCCEEECCCCCHHHHHHHHH
AAKPKIADYPFTTLVPNLGVVTTGENSFVMADVPGLIPGAAEGRGLGLEFLRHIERCAVL
HCCCCCCCCCHHHHCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
VHVVDCATLEPGRDPVSDIDALENELARYQPTLQDDSVLGDLADRPRAVVLNKVDVPEAD
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEECCCCCCHH
ELADFVTEEVSQRGWPVFKVSTLTRDGLRPLTFALWEMIVAARAARPEPVKTRPVIRPIP
HHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEECCC
VDESGFTVSADPQNPGGFVVRGVRPERWIRQTNFENDEAVGYLGDRLARLGVEDELLKLG
CCCCCCEEECCCCCCCCEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHC
AEPGCAVTIGDMTFDWEPQTPAGVDVTMSGRGTDARIDKTDRVGAAERRQARRVRRGQVE
CCCCCEEEECCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PE
CC
>Mature Secondary Structure 
PRFVDRVVIHAKAGTGGHGCASVHREKFKPLGGPDGGNGGRGGSVILEVDPQVHTLLDF
CCHHCEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEE
HFHPHLQAPNGTQGMGGHRNGANGDDLILKVPDGTVVLDDDGRILADLVGAGARFDAAAG
ECCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHCCCCCCCCCCC
GRGGLGNAALASRARKAPGFALLGEAGAEVDLTLELKTVADVGLVGFPSAGKSSLVSVLS
CCCCCCHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEHHCCCEEECCCCCHHHHHHHHH
AAKPKIADYPFTTLVPNLGVVTTGENSFVMADVPGLIPGAAEGRGLGLEFLRHIERCAVL
HCCCCCCCCCHHHHCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
VHVVDCATLEPGRDPVSDIDALENELARYQPTLQDDSVLGDLADRPRAVVLNKVDVPEAD
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEECCCCCCHH
ELADFVTEEVSQRGWPVFKVSTLTRDGLRPLTFALWEMIVAARAARPEPVKTRPVIRPIP
HHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEECCC
VDESGFTVSADPQNPGGFVVRGVRPERWIRQTNFENDEAVGYLGDRLARLGVEDELLKLG
CCCCCCEEECCCCCCCCEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHC
AEPGCAVTIGDMTFDWEPQTPAGVDVTMSGRGTDARIDKTDRVGAAERRQARRVRRGQVE
CCCCCEEEECCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA