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The map label for this gene is hsaA [H]

Identifier: 169627419

GI number: 169627419

Start: 317998

End: 319191

Strand: Direct

Name: hsaA [H]

Synonym: MAB_0315

Alternate gene names: 169627419

Gene position: 317998-319191 (Clockwise)

Preceding gene: 169627413

Following gene: 169627420

Centisome position: 6.28

GC content: 63.23

Gene sequence:

>1194_bases
ATGACGAGTTCGACAGCAGTGCAGCCAGATGCCGTACAGCGTGCGCGTGAGCTCGCTCCGGCGATCGCAGCCCGGGCGCT
GGAGGCCGAGCGGCTGCGTCGAATGCCCGATGAGACCATCGCCGAGTTGTCGCGATCGGGACTGTTCAGTTTGATGGCGC
CGCGGCGATACGGTGGCGATGAGGCAAGCCTGGAGACCTTGGTCGGTGCGGTCATCGAGGTGGGCAAGGTCTGTGGATCG
ACCGCCTGGACCTTCTGTATCTACGGGATTCACAACTGGCTGGCCGGACTGTTTCCCGAACAGTTGCAGGACGAGATGTT
CGGCTCGGTGCCCGCCGGCTCTCCCTTGCTGTTTCCGGGCAGCTGGTCGCCCTCGGGTATCGCCACCCCGGTCGAGGGCG
GCTACAAGATAACGGGGCGTTGGCAATTCGGCAGTGGTGTCTGGCACTCGTCGTGGGCGTCCGTCGCGGCAGTCGTCCAA
CACGAGGAGCCGCCGAAGTATCCGGACCTGCGTACCTTCATGATCCCCAGGTCTGATCTGGAGGTCATTGACACCTGGTT
TACTTCCGGCCTGCGAGGCACAGGAAGCATGGACATCGCGGTCAACGATGTCTTCGTTCCAGAGCACCGGGTGCAGGAAT
TCGGCCCACTGGCACGAGGGCAGTCGCCGTCCGCGGAGCTGCACGGTTCCGCTATTTACCGGATTCCGTTGTTCTGCGCC
TTGTCCAATGTCGCCGCCGCGCCTGCGGTGGGTATGGCTCTGGGCACGGTGGAGCTGTTCACCGAGAAGATCAAGACCCG
GGTGATGCGGTACTCGATGCAGGAACAGTCCAAGCTCGCTACGGCGCATAGACGGATGGGACATGTTGCGGCGCAAGCAG
AGTCGGCGCGCACCCTACTGCTACAGACCGTGCGTGACGTAGAGGACAAATTACGTTCCGGAGAGGGACTGACCACCGGG
GACCGGGTGGCGGTACGCCGCAACTGCGCCTACATCGTCGAGGTATGCAAGCAGGCCATCGGTGAGGCGGTTGAGGCGTG
TGGGGCCTCCGCGCAGTACGAGGATTCGCCGCTGCAGCGACACCTGCGCGACGTGAATACGTTGTCCACTCATGTTGTCT
ACGACACAGATTCGGCTTACGAGCTGTACGGGCGGGTGGAACTCGGGCTGCCGCCGGGATCCGTCGCGTTCTGA

Upstream 100 bases:

>100_bases
CATCACCACGCCGCCAAGGCTACATTAAACCTGAATCGTGATTCAGTTTCGGTCCGATCGCATGTCATCCACTAATGATT
GCGCAGGTTGCGAGGTTTTG

Downstream 100 bases:

>100_bases
TGGGTGTCGGCTCGTGAACGCTGGGATACCGGAGCTCACCGGGTTGCGTTGTGCGCTCGATGACCGGGTGCTGACGGTCC
TGTTCGATCACGGCCAGCTC

Product: hypothetical protein

Products: NA

Alternate protein names: 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione 4-hydroxylase [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MTSSTAVQPDAVQRARELAPAIAARALEAERLRRMPDETIAELSRSGLFSLMAPRRYGGDEASLETLVGAVIEVGKVCGS
TAWTFCIYGIHNWLAGLFPEQLQDEMFGSVPAGSPLLFPGSWSPSGIATPVEGGYKITGRWQFGSGVWHSSWASVAAVVQ
HEEPPKYPDLRTFMIPRSDLEVIDTWFTSGLRGTGSMDIAVNDVFVPEHRVQEFGPLARGQSPSAELHGSAIYRIPLFCA
LSNVAAAPAVGMALGTVELFTEKIKTRVMRYSMQEQSKLATAHRRMGHVAAQAESARTLLLQTVRDVEDKLRSGEGLTTG
DRVAVRRNCAYIVEVCKQAIGEAVEACGASAQYEDSPLQRHLRDVNTLSTHVVYDTDSAYELYGRVELGLPPGSVAF

Sequences:

>Translated_397_residues
MTSSTAVQPDAVQRARELAPAIAARALEAERLRRMPDETIAELSRSGLFSLMAPRRYGGDEASLETLVGAVIEVGKVCGS
TAWTFCIYGIHNWLAGLFPEQLQDEMFGSVPAGSPLLFPGSWSPSGIATPVEGGYKITGRWQFGSGVWHSSWASVAAVVQ
HEEPPKYPDLRTFMIPRSDLEVIDTWFTSGLRGTGSMDIAVNDVFVPEHRVQEFGPLARGQSPSAELHGSAIYRIPLFCA
LSNVAAAPAVGMALGTVELFTEKIKTRVMRYSMQEQSKLATAHRRMGHVAAQAESARTLLLQTVRDVEDKLRSGEGLTTG
DRVAVRRNCAYIVEVCKQAIGEAVEACGASAQYEDSPLQRHLRDVNTLSTHVVYDTDSAYELYGRVELGLPPGSVAF
>Mature_396_residues
TSSTAVQPDAVQRARELAPAIAARALEAERLRRMPDETIAELSRSGLFSLMAPRRYGGDEASLETLVGAVIEVGKVCGST
AWTFCIYGIHNWLAGLFPEQLQDEMFGSVPAGSPLLFPGSWSPSGIATPVEGGYKITGRWQFGSGVWHSSWASVAAVVQH
EEPPKYPDLRTFMIPRSDLEVIDTWFTSGLRGTGSMDIAVNDVFVPEHRVQEFGPLARGQSPSAELHGSAIYRIPLFCAL
SNVAAAPAVGMALGTVELFTEKIKTRVMRYSMQEQSKLATAHRRMGHVAAQAESARTLLLQTVRDVEDKLRSGEGLTTGD
RVAVRRNCAYIVEVCKQAIGEAVEACGASAQYEDSPLQRHLRDVNTLSTHVVYDTDSAYELYGRVELGLPPGSVAF

Specific function: Catalyzes the o-hydroxylation of 3-hydroxy-9,10- seconandrost-1,3,5(10)-triene-9,17-dione (3-HSA) to 3,4-dihydroxy- 9,10-seconandrost-1,3,5(10)-triene-9,17-dione (3,4-DHSA) in the catabolism of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FADH(2)-utilizing monooxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 43130; Mature: 42999

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSTAVQPDAVQRARELAPAIAARALEAERLRRMPDETIAELSRSGLFSLMAPRRYGGD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCCCCCC
EASLETLVGAVIEVGKVCGSTAWTFCIYGIHNWLAGLFPEQLQDEMFGSVPAGSPLLFPG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECC
SWSPSGIATPVEGGYKITGRWQFGSGVWHSSWASVAAVVQHEEPPKYPDLRTFMIPRSDL
CCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCH
EVIDTWFTSGLRGTGSMDIAVNDVFVPEHRVQEFGPLARGQSPSAELHGSAIYRIPLFCA
HHHHHHHHCCCCCCCCEEEEEEEEECCHHHHHHHCCHHCCCCCCCHHCCCCHHHHHHHHH
LSNVAAAPAVGMALGTVELFTEKIKTRVMRYSMQEQSKLATAHRRMGHVAAQAESARTLL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQTVRDVEDKLRSGEGLTTGDRVAVRRNCAYIVEVCKQAIGEAVEACGASAQYEDSPLQR
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
HLRDVNTLSTHVVYDTDSAYELYGRVELGLPPGSVAF
HHHHHHHHHEEEEECCCCCEEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
TSSTAVQPDAVQRARELAPAIAARALEAERLRRMPDETIAELSRSGLFSLMAPRRYGGD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCCCCCC
EASLETLVGAVIEVGKVCGSTAWTFCIYGIHNWLAGLFPEQLQDEMFGSVPAGSPLLFPG
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECC
SWSPSGIATPVEGGYKITGRWQFGSGVWHSSWASVAAVVQHEEPPKYPDLRTFMIPRSDL
CCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCH
EVIDTWFTSGLRGTGSMDIAVNDVFVPEHRVQEFGPLARGQSPSAELHGSAIYRIPLFCA
HHHHHHHHCCCCCCCCEEEEEEEEECCHHHHHHHCCHHCCCCCCCHHCCCCHHHHHHHHH
LSNVAAAPAVGMALGTVELFTEKIKTRVMRYSMQEQSKLATAHRRMGHVAAQAESARTLL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQTVRDVEDKLRSGEGLTTGDRVAVRRNCAYIVEVCKQAIGEAVEACGASAQYEDSPLQR
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
HLRDVNTLSTHVVYDTDSAYELYGRVELGLPPGSVAF
HHHHHHHHHEEEEECCCCCEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA