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The map label for this gene is lytA [H]

Identifier: 169832688

GI number: 169832688

Start: 439430

End: 440449

Strand: Direct

Name: lytA [H]

Synonym: SPH_0484

Alternate gene names: 169832688

Gene position: 439430-440449 (Clockwise)

Preceding gene: 169832776

Following gene: 169833764

Centisome position: 19.57

GC content: 38.63

Gene sequence:

>1020_bases
ATGAAGCTTTTGAAAAAAATGATGCCAATCGCATTAGCAGTCTTTTTCTTTGGTTTGCTAGCGACAAATACGGTATTTGC
GAATACCACAGGTGGCCGATTTGTTGATAAGGATAATAGAAAATATTATGTAAAAGATGATCATAAAGCAATCTATTGGC
ATAAAATAGACGGTAAAACTTACTATTTTGGTGATATTGGAGAGATGGTTGTCGGTTGGCAATACTTAGAAATTCCTGGA
ACAGGTTATCGTGATAATTTATTCGATAATCAACCAGTTAATGAAATTGGCCTTCAGGAGAAGTGGTACTATTTTGGACA
AGATGGTGCTTTGCTAGAACAAACAGATAAACAAGTACTAGAGGCAAAAACGTCTGAAAATACAGGAAAAGTATACGGTG
AACAATATCCTCTATCTGCTGAAAAGAGAACTTATTATTTTGATAATAATTATGCTGTAAAGACAGGCTGGATTTATGAA
GAGGGTCATTGGTATTATTTAAATAAGCTAGGAAATTTTGGCGATGATTCTTACAATCCACTACCAATTGGTGAAGTTGC
TAAGGGTTGGACTCAAGATTTTCATGTTACTATTGACATTGATAGAAGCAAACCTGCTCCATGGTACTACCTAGATCCAA
CAACTGGTATTATGCAAACAGGTTGGCAATATCTAGGTAATAAGTGGTACTACCTCCGTTCCTCAGGAGCAATGGCCACT
GGCTGGTATCAGGAAGGTACCACTTGGTATTATTTAGACCACCCAAATGGCGATATGAAAACAGGTTGGCAAAACCTTGG
GAACAAATGGTACTATCTCCGTTCATCAGGAGCTATGGCAACTGGTTGGTATCAAGATGGTTCAACTTGGTACTACCTAA
ATGCAGGTAATGGAGACATGAAGACAGGTTGGTTCCAGGTCAATGGCAACTGGTACTATGCTTATAGCTCAGGTGCTTTG
GCAGTGAATACGACCGTAGATGGCTATTCTGTCAACTATAATGGCGAATGGGTTCGGTAA

Upstream 100 bases:

>100_bases
AGAAAAGCAGTTGCAGTTGTGTAACTGCTTTTTTGAGGAGTTTTTATATATTGACATACAATCTAGTTTTTACTACAATC
GTTTTAGGAGGATATATAAA

Downstream 100 bases:

>100_bases
TGACAGGGCGCTTATAATTATATTAGAACACTCGCTTAATCAAAGAAGTGACTTTGTTGTACTTGACCTGACGATTGGGG
AGATTAAAAGCATGTGAAAT

Product: choline-binding protein F

Products: NA

Alternate protein names: Cell wall hydrolase; Mucopeptide aminohydrolase; Murein hydrolase; N-acetylmuramoyl-L-alanine amidase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKLLKKMMPIALAVFFFGLLATNTVFANTTGGRFVDKDNRKYYVKDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPG
TGYRDNLFDNQPVNEIGLQEKWYYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIMQTGWQYLGNKWYYLRSSGAMAT
GWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGAL
AVNTTVDGYSVNYNGEWVR

Sequences:

>Translated_339_residues
MKLLKKMMPIALAVFFFGLLATNTVFANTTGGRFVDKDNRKYYVKDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPG
TGYRDNLFDNQPVNEIGLQEKWYYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIMQTGWQYLGNKWYYLRSSGAMAT
GWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGAL
AVNTTVDGYSVNYNGEWVR
>Mature_339_residues
MKLLKKMMPIALAVFFFGLLATNTVFANTTGGRFVDKDNRKYYVKDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPG
TGYRDNLFDNQPVNEIGLQEKWYYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIMQTGWQYLGNKWYYLRSSGAMAT
GWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGAL
AVNTTVDGYSVNYNGEWVR

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Autolysin strictly depends on the presence of choline-containing

COG id: COG5263

COG function: function code R; FOG: Glucan-binding domain (YG repeat)

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 6 cell wall-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002502
- InterPro:   IPR018337 [H]

Pfam domain/function: PF01510 Amidase_2; PF01473 CW_binding_1 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 39356; Mature: 39356

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLKKMMPIALAVFFFGLLATNTVFANTTGGRFVDKDNRKYYVKDDHKAIYWHKIDGKT
CCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCEEEEECCCEEEEEEEECCCE
YYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKWYYFGQDGALLEQTDKQVL
EEECCCCCHHCCEEEEEECCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCHHHHHHHHH
EAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYEEGHWYYLNKLGNFGDDSYNP
HHCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEECCCEEEEECCCCCCCCCCCC
LPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIMQTGWQYLGNKWYYLRSSGAMAT
CCHHHHHCCCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCCEEE
GWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGNGDM
EEEECCCEEEEEECCCCCCCHHHHHCCCEEEEEECCCCEEEEEEECCCEEEEEECCCCCC
KTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR
EEEEEEECCEEEEEEECCEEEEEEEECCEEEECCCCEEC
>Mature Secondary Structure
MKLLKKMMPIALAVFFFGLLATNTVFANTTGGRFVDKDNRKYYVKDDHKAIYWHKIDGKT
CCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCEEEEECCCEEEEEEEECCCE
YYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKWYYFGQDGALLEQTDKQVL
EEECCCCCHHCCEEEEEECCCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCHHHHHHHHH
EAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYEEGHWYYLNKLGNFGDDSYNP
HHCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEEECCCEEEEECCCCCCCCCCCC
LPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIMQTGWQYLGNKWYYLRSSGAMAT
CCHHHHHCCCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCCEEE
GWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGNGDM
EEEECCCEEEEEECCCCCCCHHHHHCCCEEEEEECCCCEEEEEEECCCEEEEEECCCCCC
KTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR
EEEEEEECCEEEEEEECCEEEEEEEECCEEEECCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2875013; 11463916 [H]