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The map label for this gene is potC [H]

Identifier: 169824262

GI number: 169824262

Start: 627236

End: 628009

Strand: Direct

Name: potC [H]

Synonym: FMG_0565

Alternate gene names: 169824262

Gene position: 627236-628009 (Clockwise)

Preceding gene: 169824261

Following gene: 169824263

Centisome position: 34.89

GC content: 32.56

Gene sequence:

>774_bases
ATGAAAGAATTTTTCAAGAAATTTTATTTAGCATTGGTATTTTTATTCCTTTACGGACCAATTGCTGTTTTGATGGTATT
TTCATTTAACGATTCTCGTTTGAAAGGAAGCTGGGTTGGATTTACTTTCAAATGGTACAAGGAATTATTGCACAATGAAG
AAATCTTGTCATCATTTAAAACGACTATTTTGATTGCCATACTAGCAACAATAATCGCTACAATTTTGGGAACGATAGCT
GCAATAGGAATTTATTATTTAAGAGGATACAAAAAATCTTTGCTTTTAAATATGAATTATCTTCCGGTTTTAAATCCTGA
TATCGTGACAGCGGTTGGCCTAATGGTAATATTTAACTTGATGAATTTTCCATTTGGATTTTTTACAATGTTGTTGTCAC
ATATAACATTTACAACACCTTATGTAATACTTGCTGTGTTGCCGAAATTAGCACAAATGAATAAATTTTTGCCAGAGGCT
GCGATGGATATGGGAGCAACTCCATTCTACACTTTGAGAAAAGTTGTATTGCCAGAAATTAAAACAGGAGTTTTTTCGGG
AAGTTTGTTGGCATTTACACTTAGCATAGATGATTTTGTAATCAGTTTCTTCACGACAGGTCACGGCGTATCAAATCTTT
CAGTTACAGTGTACTCTATGGCGAAAAAAGGTGTTAATCCAGCAATTAATGCTTTAAGCACAATTATGTTTTTGGTAATG
GTTATTCTATTGTTGATTCTTCACAAGAGAACAAATCTATTGGAGGAGTTATAA

Upstream 100 bases:

>100_bases
AGGATAGCTGGAAATTGGCATTACGGTAGTGCAATTTCTGTAGTACTTATAATTATGATTTTAATTTCATTAGCTTTTAC
GAATGAGAAGGGAGAATAAA

Downstream 100 bases:

>100_bases
TATGAAGAAAATTTTATTATTTTTATTAACTATATTGGTTTTGACTTCTTGCTCCAAGGATGAATCGAATGTCTTGTATG
TGTACAATTGGGGAGAGTAC

Product: spermidine/putrescine ABC transporter permease

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKEFFKKFYLALVFLFLYGPIAVLMVFSFNDSRLKGSWVGFTFKWYKELLHNEEILSSFKTTILIAILATIIATILGTIA
AIGIYYLRGYKKSLLLNMNYLPVLNPDIVTAVGLMVIFNLMNFPFGFFTMLLSHITFTTPYVILAVLPKLAQMNKFLPEA
AMDMGATPFYTLRKVVLPEIKTGVFSGSLLAFTLSIDDFVISFFTTGHGVSNLSVTVYSMAKKGVNPAINALSTIMFLVM
VILLLILHKRTNLLEEL

Sequences:

>Translated_257_residues
MKEFFKKFYLALVFLFLYGPIAVLMVFSFNDSRLKGSWVGFTFKWYKELLHNEEILSSFKTTILIAILATIIATILGTIA
AIGIYYLRGYKKSLLLNMNYLPVLNPDIVTAVGLMVIFNLMNFPFGFFTMLLSHITFTTPYVILAVLPKLAQMNKFLPEA
AMDMGATPFYTLRKVVLPEIKTGVFSGSLLAFTLSIDDFVISFFTTGHGVSNLSVTVYSMAKKGVNPAINALSTIMFLVM
VILLLILHKRTNLLEEL
>Mature_257_residues
MKEFFKKFYLALVFLFLYGPIAVLMVFSFNDSRLKGSWVGFTFKWYKELLHNEEILSSFKTTILIAILATIIATILGTIA
AIGIYYLRGYKKSLLLNMNYLPVLNPDIVTAVGLMVIFNLMNFPFGFFTMLLSHITFTTPYVILAVLPKLAQMNKFLPEA
AMDMGATPFYTLRKVVLPEIKTGVFSGSLLAFTLSIDDFVISFFTTGHGVSNLSVTVYSMAKKGVNPAINALSTIMFLVM
VILLLILHKRTNLLEEL

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=220, Percent_Identity=40.9090909090909, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1787081, Length=243, Percent_Identity=37.4485596707819, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1787714, Length=207, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788764, Length=206, Percent_Identity=25.7281553398058, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28877; Mature: 28877

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKEFFKKFYLALVFLFLYGPIAVLMVFSFNDSRLKGSWVGFTFKWYKELLHNEEILSSFK
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHH
TTILIAILATIIATILGTIAAIGIYYLRGYKKSLLLNMNYLPVLNPDIVTAVGLMVIFNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
MNFPFGFFTMLLSHITFTTPYVILAVLPKLAQMNKFLPEAAMDMGATPFYTLRKVVLPEI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KTGVFSGSLLAFTLSIDDFVISFFTTGHGVSNLSVTVYSMAKKGVNPAINALSTIMFLVM
HHHHCCCHHHHEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VILLLILHKRTNLLEEL
HHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]