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The map label for this gene is pdxK [H]

Identifier: 169824119

GI number: 169824119

Start: 480538

End: 481323

Strand: Direct

Name: pdxK [H]

Synonym: FMG_0422

Alternate gene names: 169824119

Gene position: 480538-481323 (Clockwise)

Preceding gene: 169824116

Following gene: 169824120

Centisome position: 26.73

GC content: 32.82

Gene sequence:

>786_bases
ATGAAAGATATTTTATTAATCAACGATATGCCAGGATATGGGAGAGTCGCTCTTAGTTGTATGATTCCTGTGCTGAGTAA
TAAAGGAAAAAGCGTTTTTAATTTGCCAACAGCAGTTGTGAGTAACACATTGGATTATGGAAAATTTGCGATTTTAGATA
CAACAGAATACATGAAACAAGCGACAAAAGTTTGGGAGGAATTGGATTTTAGTTTTGATTTGATTGCTACTGGATTTTTG
AATAGCTTAGAACAAGTGGATATTATCAAAGATTTTATAGCTAAACAAAAAAACTCGCCAGAGGTCGTTGTCGATCCCAT
AATGGCAGACAATGGGAAACTCTACAACGGATTGAATGAGGACAATATTGAAAATTTTAGAAGACTAATCGACGTAGCTA
CAGTGATTATTCCAAACGAAACTGAAGCTAGAATGATTGCAAATATGATGAATGAACCTATAAATGATGTAGCCAAAAAG
CTTATAGAAATGGGAGCAAAATACGTTGTCATTACCAGTGCAGAAGAAAATAACGAGCATTTTGTTTTTTGTATGGATGA
AAATTTTGTATCAGATAAAATTTATTATGAATACATCAACACATCTTATGCAGGAACAGGGGATTTGTTCTCAGCGTTAT
TTATAAGCCAATATTCAGAAAACAAATCGATTTTTGATTCTGCAAAGTATGCAAGCTTGAAAACAACAGAACTGTTGAAA
CTTTCATTGGATATTAAAGACAAAGCTCGTGGTTTACCAATAGAAAGGTTTATAGATATTTTGTAA

Upstream 100 bases:

>100_bases
GAAATTATGAGGATTTAAAAGCCAAAAATCTACAAAATGATTAAGATTTATTTGATATACAAATATGATTTTAGTGTTAT
AATTAGATGGAGGAGAAAAC

Downstream 100 bases:

>100_bases
ACTGTAATTTTAAATAAATATAAGAAAATAATGAATATTACATTGTAAATTGTATATTCAATTGTTATAATGATATTGCA
TAAAAATATTAGGGGGATAA

Product: pyridoxal kinase

Products: NA

Alternate protein names: PN/PL/PM kinase; Pyridoxal kinase; Pyridoxamine kinase; Vitamin B6 kinase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKDILLINDMPGYGRVALSCMIPVLSNKGKSVFNLPTAVVSNTLDYGKFAILDTTEYMKQATKVWEELDFSFDLIATGFL
NSLEQVDIIKDFIAKQKNSPEVVVDPIMADNGKLYNGLNEDNIENFRRLIDVATVIIPNETEARMIANMMNEPINDVAKK
LIEMGAKYVVITSAEENNEHFVFCMDENFVSDKIYYEYINTSYAGTGDLFSALFISQYSENKSIFDSAKYASLKTTELLK
LSLDIKDKARGLPIERFIDIL

Sequences:

>Translated_261_residues
MKDILLINDMPGYGRVALSCMIPVLSNKGKSVFNLPTAVVSNTLDYGKFAILDTTEYMKQATKVWEELDFSFDLIATGFL
NSLEQVDIIKDFIAKQKNSPEVVVDPIMADNGKLYNGLNEDNIENFRRLIDVATVIIPNETEARMIANMMNEPINDVAKK
LIEMGAKYVVITSAEENNEHFVFCMDENFVSDKIYYEYINTSYAGTGDLFSALFISQYSENKSIFDSAKYASLKTTELLK
LSLDIKDKARGLPIERFIDIL
>Mature_261_residues
MKDILLINDMPGYGRVALSCMIPVLSNKGKSVFNLPTAVVSNTLDYGKFAILDTTEYMKQATKVWEELDFSFDLIATGFL
NSLEQVDIIKDFIAKQKNSPEVVVDPIMADNGKLYNGLNEDNIENFRRLIDVATVIIPNETEARMIANMMNEPINDVAKK
LIEMGAKYVVITSAEENNEHFVFCMDENFVSDKIYYEYINTSYAGTGDLFSALFISQYSENKSIFDSAKYASLKTTELLK
LSLDIKDKARGLPIERFIDIL

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxal, pyridoxine, and pyridoxamine as substrates [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788758, Length=254, Percent_Identity=29.9212598425197, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 29474; Mature: 29474

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDILLINDMPGYGRVALSCMIPVLSNKGKSVFNLPTAVVSNTLDYGKFAILDTTEYMKQ
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHCCCCCCCEEEEECHHHHHH
ATKVWEELDFSFDLIATGFLNSLEQVDIIKDFIAKQKNSPEVVVDPIMADNGKLYNGLNE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCEECCCCCEECCCCC
DNIENFRRLIDVATVIIPNETEARMIANMMNEPINDVAKKLIEMGAKYVVITSAEENNEH
CCHHHHHHHHHHHHEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCE
FVFCMDENFVSDKIYYEYINTSYAGTGDLFSALFISQYSENKSIFDSAKYASLKTTELLK
EEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHEEEE
LSLDIKDKARGLPIERFIDIL
EEECCHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MKDILLINDMPGYGRVALSCMIPVLSNKGKSVFNLPTAVVSNTLDYGKFAILDTTEYMKQ
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHCCCCCCCEEEEECHHHHHH
ATKVWEELDFSFDLIATGFLNSLEQVDIIKDFIAKQKNSPEVVVDPIMADNGKLYNGLNE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCEECCCCCEECCCCC
DNIENFRRLIDVATVIIPNETEARMIANMMNEPINDVAKKLIEMGAKYVVITSAEENNEH
CCHHHHHHHHHHHHEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCCCCCE
FVFCMDENFVSDKIYYEYINTSYAGTGDLFSALFISQYSENKSIFDSAKYASLKTTELLK
EEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHEEEE
LSLDIKDKARGLPIERFIDIL
EEECCHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA