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The map label for this gene is gltP [C]

Identifier: 169824116

GI number: 169824116

Start: 476685

End: 477965

Strand: Direct

Name: gltP [C]

Synonym: FMG_0419

Alternate gene names: 169824116

Gene position: 476685-477965 (Clockwise)

Preceding gene: 169824115

Following gene: 169824119

Centisome position: 26.52

GC content: 33.33

Gene sequence:

>1281_bases
ATGATTAAAAGCTTAATCGCTTTAGTTGTAGCTTTCGCATTATGCGTTGTCATTGATCGTTTGAAGAAAAAAGGTACTTC
ATTCATGATCAGAATTTTATTAGCTACAGCAATGGGTGCCATAGTAGGACTTATTTTTAAAGGAGCCACAGACTACGTAG
CAATATTTGGTCGTGTGTTTATTAGTTTATTACAAGCATTTGTAATTCCATTATTATTATTCTCAATTATAACTACAGTT
GCATCCTTGGAAAGCACAGAAAAATTAAGATCAACAGGAGGAAAGACAATTGGTATACTAGCTTTACACAATGTTTTAGC
TTCTGTTGCTGCACTAATTTTAGGTAAATTGGTTAATTTAGGGGTAAATGCAAATATTAAAATGGATGTTACTGATAAGG
TAAAAGAAGTTCCACCTTTCTCAGATGTATTTGTAAGTTTCTTCCCTAAAAACATTGTAGATAGTATGCTACATACTAAA
GTTGTTCCAATAGTCATTTTTGCTGTTATAATTGGTGTTACTGCATTAAAGTATTCGAATAAAGATGAAATTAAACCATT
TATGGATTTTACAGCAGCTGCTAACAAAGTAATGAACAAAGTAATTGGAGAAATCATAGAATTTACTCCATACGCAGTTC
TTTCATTATTAGCTCACCAAGTAGCTACTTTGGATTTATCATTTGTTGCATCATTATTATTCTTATTATTAATGGTTTAT
GTATGCTGTTTCTTCCACACATTCATAACTACGACAGTGATGTTAAAATTTATGGCACATGTCAATCCATTTAAGTTCCA
ACGTAAATTCTTCCCAGCATGGTTATTAGGATTTACAACTCAAAGTTCATTGGGAACTTTACCAGAAAACATTAGAGAAC
AAGAAAAAATGGGTGTTCCAACAGAAACTGCATCATTTGCAGGATCAATTGGTACTACATTTGGTATGCCAGGTTGTGCA
GCTGTATGGAATATTTTATTAGCGGTTTTCACAATAAACGCTCTTAATATTCCATTTACAATTACACAATATGTAATAAT
GGTATTTACTGCACTTCTTGCTTCTGCAGGAACAGTGGGGGTTCCAGGAACTGGTACTATGTTAAATGTAGCTTTATTTA
CAGCTATGGGATTACCTCTAGAAATGATTCTAGTACTAAGCCCAATCCAAGGCGTTGCTGATATGGCACGTACTTCAACT
AACGTTCACGCAGGTGGATCTACTGGTATTATAGTAGCAGCAATGCAACACGATTTAGATCTTGAAAAATATAATTCATA
A

Upstream 100 bases:

>100_bases
ATAAATTTTGTGAAAACGATACATCTAAATATAAATCATTGTCTATTATAAGACAATATGATAAGATTAGTTTGAAAAAA
ATTTAAAAGGAGATGTTGAT

Downstream 100 bases:

>100_bases
TTGATTTTAAATAGAGGCTTTTTGAATTTTCAAAATAGCTTCTATTTTTTTTTGAAATTATTAAATCTTATTTTTACAAA
AAACAAAGGATAGGCATTTG

Product: proton/sodium-glutamate symporter

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MIKSLIALVVAFALCVVIDRLKKKGTSFMIRILLATAMGAIVGLIFKGATDYVAIFGRVFISLLQAFVIPLLLFSIITTV
ASLESTEKLRSTGGKTIGILALHNVLASVAALILGKLVNLGVNANIKMDVTDKVKEVPPFSDVFVSFFPKNIVDSMLHTK
VVPIVIFAVIIGVTALKYSNKDEIKPFMDFTAAANKVMNKVIGEIIEFTPYAVLSLLAHQVATLDLSFVASLLFLLLMVY
VCCFFHTFITTTVMLKFMAHVNPFKFQRKFFPAWLLGFTTQSSLGTLPENIREQEKMGVPTETASFAGSIGTTFGMPGCA
AVWNILLAVFTINALNIPFTITQYVIMVFTALLASAGTVGVPGTGTMLNVALFTAMGLPLEMILVLSPIQGVADMARTST
NVHAGGSTGIIVAAMQHDLDLEKYNS

Sequences:

>Translated_426_residues
MIKSLIALVVAFALCVVIDRLKKKGTSFMIRILLATAMGAIVGLIFKGATDYVAIFGRVFISLLQAFVIPLLLFSIITTV
ASLESTEKLRSTGGKTIGILALHNVLASVAALILGKLVNLGVNANIKMDVTDKVKEVPPFSDVFVSFFPKNIVDSMLHTK
VVPIVIFAVIIGVTALKYSNKDEIKPFMDFTAAANKVMNKVIGEIIEFTPYAVLSLLAHQVATLDLSFVASLLFLLLMVY
VCCFFHTFITTTVMLKFMAHVNPFKFQRKFFPAWLLGFTTQSSLGTLPENIREQEKMGVPTETASFAGSIGTTFGMPGCA
AVWNILLAVFTINALNIPFTITQYVIMVFTALLASAGTVGVPGTGTMLNVALFTAMGLPLEMILVLSPIQGVADMARTST
NVHAGGSTGIIVAAMQHDLDLEKYNS
>Mature_426_residues
MIKSLIALVVAFALCVVIDRLKKKGTSFMIRILLATAMGAIVGLIFKGATDYVAIFGRVFISLLQAFVIPLLLFSIITTV
ASLESTEKLRSTGGKTIGILALHNVLASVAALILGKLVNLGVNANIKMDVTDKVKEVPPFSDVFVSFFPKNIVDSMLHTK
VVPIVIFAVIIGVTALKYSNKDEIKPFMDFTAAANKVMNKVIGEIIEFTPYAVLSLLAHQVATLDLSFVASLLFLLLMVY
VCCFFHTFITTTVMLKFMAHVNPFKFQRKFFPAWLLGFTTQSSLGTLPENIREQEKMGVPTETASFAGSIGTTFGMPGCA
AVWNILLAVFTINALNIPFTITQYVIMVFTALLASAGTVGVPGTGTMLNVALFTAMGLPLEMILVLSPIQGVADMARTST
NVHAGGSTGIIVAAMQHDLDLEKYNS

Specific function: This Carrier Protein Is Part Of The Na(+)-Independent, Binding-Protein-Independent Glutamate-Aspartate Transport System. [C]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI4827012, Length=265, Percent_Identity=29.4339622641509, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI40254478, Length=244, Percent_Identity=29.0983606557377, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI169790839, Length=253, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI66773030, Length=264, Percent_Identity=25.7575757575758, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI21314632, Length=413, Percent_Identity=23.4866828087167, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI194239697, Length=246, Percent_Identity=25.2032520325203, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI223468564, Length=251, Percent_Identity=23.9043824701195, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI223468566, Length=251, Percent_Identity=23.9043824701195, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1790514, Length=380, Percent_Identity=23.9473684210526, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1788024, Length=407, Percent_Identity=29.7297297297297, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789947, Length=410, Percent_Identity=22.1951219512195, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789473, Length=350, Percent_Identity=24.8571428571429, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71996953, Length=462, Percent_Identity=22.7272727272727, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17537407, Length=428, Percent_Identity=24.2990654205607, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71983106, Length=445, Percent_Identity=22.247191011236, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71983099, Length=445, Percent_Identity=22.247191011236, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193206654, Length=457, Percent_Identity=19.6936542669584, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193206505, Length=409, Percent_Identity=21.5158924205379, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17541374, Length=405, Percent_Identity=22.4691358024691, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24583025, Length=414, Percent_Identity=22.463768115942, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17137668, Length=414, Percent_Identity=22.463768115942, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24583023, Length=414, Percent_Identity=22.463768115942, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 45922; Mature: 45922

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKSLIALVVAFALCVVIDRLKKKGTSFMIRILLATAMGAIVGLIFKGATDYVAIFGRVF
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ISLLQAFVIPLLLFSIITTVASLESTEKLRSTGGKTIGILALHNVLASVAALILGKLVNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHC
GVNANIKMDVTDKVKEVPPFSDVFVSFFPKNIVDSMLHTKVVPIVIFAVIIGVTALKYSN
CCCCCEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KDEIKPFMDFTAAANKVMNKVIGEIIEFTPYAVLSLLAHQVATLDLSFVASLLFLLLMVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VCCFFHTFITTTVMLKFMAHVNPFKFQRKFFPAWLLGFTTQSSLGTLPENIREQEKMGVP
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHCCCC
TETASFAGSIGTTFGMPGCAAVWNILLAVFTINALNIPFTITQYVIMVFTALLASAGTVG
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
VPGTGTMLNVALFTAMGLPLEMILVLSPIQGVADMARTSTNVHAGGSTGIIVAAMQHDLD
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHCCC
LEKYNS
HHHCCC
>Mature Secondary Structure
MIKSLIALVVAFALCVVIDRLKKKGTSFMIRILLATAMGAIVGLIFKGATDYVAIFGRVF
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ISLLQAFVIPLLLFSIITTVASLESTEKLRSTGGKTIGILALHNVLASVAALILGKLVNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHC
GVNANIKMDVTDKVKEVPPFSDVFVSFFPKNIVDSMLHTKVVPIVIFAVIIGVTALKYSN
CCCCCEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KDEIKPFMDFTAAANKVMNKVIGEIIEFTPYAVLSLLAHQVATLDLSFVASLLFLLLMVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VCCFFHTFITTTVMLKFMAHVNPFKFQRKFFPAWLLGFTTQSSLGTLPENIREQEKMGVP
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHCCCC
TETASFAGSIGTTFGMPGCAAVWNILLAVFTINALNIPFTITQYVIMVFTALLASAGTVG
CCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
VPGTGTMLNVALFTAMGLPLEMILVLSPIQGVADMARTSTNVHAGGSTGIIVAAMQHDLD
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHCCC
LEKYNS
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]