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The map label for this gene is sdaC [H]

Identifier: 167623811

GI number: 167623811

Start: 2258968

End: 2260260

Strand: Direct

Name: sdaC [H]

Synonym: Shal_1881

Alternate gene names: 167623811

Gene position: 2258968-2260260 (Clockwise)

Preceding gene: 167623810

Following gene: 167623812

Centisome position: 43.22

GC content: 45.55

Gene sequence:

>1293_bases
ATGGACTCTGTAATTAACAAAACTGAAAATGCCTCGGCACAAGTCAAGGTCAAATCAAGCTGGAGCAAGAGCGATACTCT
ATGGGTATTAGGGCTCTATGGTACGGCCGTGGGGGCTGGCACCCTTTTCCTGCCAATTAATGCGGCTCAAGGTGGCTTGA
TCCCTCTCATTATCATGGCACTGCTGGCACTGCCAATGACCTTCTTCGCTCATCGTGGATTGACCCGTTTTGTGTTATCG
GGTTCAAATCCAGAAGCTGGGATCACCGAAGTGGTAGAGGAGCATTTTGGCGTCGGTATGGGCAAGGTTATCACCTTACT
CTACTTCTTTGCTATCTACCCGATTTTGCTTGTCTACAGTGTTGCGCTTACCAATACTGTCGAAAGCTTTATGCAACATC
AGCTGAATATAGCACCGCCTAACCGCGCCACATTAGCCTTAATCTTGATTATTGGTTTGATCGCCGTGGTTCGCTTAGGT
GAGCAGTTAATTATCAAAGCGATGAGTGTGCTGGTTTTCCCATTCGTTGCCGTCCTCTTGCTGCTTTCCGTTTACCTAAT
TCCTTACTGGAACACGTCAATATTTAACAATGTGATGCCAGCAGATGGAGGAATAAGCACTATCTTAATGGCATTGTGGT
TAATACTGCCTGTGATGGTATTTTCATTTAATCACTCTCCGGTTATCTCCTCCTTTGCGGTCGATCGTAGGAAAGCTCAC
GGTGAAAATGCCGACAAACAGTGTTCACGGATCTTAGCGTTCAGCCATATCCTTATGGTTGTCACTGTGATGTTTTTCGT
ATTTAGTTGCGTATTTAGTTTATCTCCAGCCAATTTAGCAGAGGCGAAAGCGCAAAATGTGTCGATATTAACGTATCTGG
CAAACCATTTTGATACGCCGATTATCGCCTATGTCGCGCCAATTGTTGCGATCATCGCTATCACTAAGTCATTCTTTGGC
CACTATATCGGGGCGAGTGAAGGCTTTAATGGTTTAATCATCAAGGCTGCACGCGGCAAGGGAAAAGAGGTTAATCTTGT
CACTCTGAACCGTGTTACCGCAGGTTTTATGCTATTGACCACGTGGGCCGTAGCCACAATCAACCCGAATATTTTGGGAA
TGATTGAAAGCCTAGGTGGACCAATCATCGCGCTGCTGCTGTTTATTATGCCGATGTACGCCATCATGAAAGTGCCGGCG
ATGAAGCAATACTCGGGTGCCATAAGCAATGTTTTTGTGGTGATTATCGGATTGGTATCAATCTCGGCAATCTTCTATTC
ATTGGTGCAGTAA

Upstream 100 bases:

>100_bases
CGCCTATATGATGTGGCGATCTGGCTATGTGATGCGATTAAGCTATGTAAACAGAACCCTTAAAAGGTCATATAAGAGCC
GATTTAAGGAGATGTCCATT

Downstream 100 bases:

>100_bases
AACGACGAAGAGGGCAAGAGCCATTGGTTTTTGCTCTCTCTTCCTGCTTTTTCGCCTTCTGCTCACTGGCCGAGCCTGTT
CATTTTAAGCTGTACTTTTT

Product: putative serine transporter

Products: Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MDSVINKTENASAQVKVKSSWSKSDTLWVLGLYGTAVGAGTLFLPINAAQGGLIPLIIMALLALPMTFFAHRGLTRFVLS
GSNPEAGITEVVEEHFGVGMGKVITLLYFFAIYPILLVYSVALTNTVESFMQHQLNIAPPNRATLALILIIGLIAVVRLG
EQLIIKAMSVLVFPFVAVLLLLSVYLIPYWNTSIFNNVMPADGGISTILMALWLILPVMVFSFNHSPVISSFAVDRRKAH
GENADKQCSRILAFSHILMVVTVMFFVFSCVFSLSPANLAEAKAQNVSILTYLANHFDTPIIAYVAPIVAIIAITKSFFG
HYIGASEGFNGLIIKAARGKGKEVNLVTLNRVTAGFMLLTTWAVATINPNILGMIESLGGPIIALLLFIMPMYAIMKVPA
MKQYSGAISNVFVVIIGLVSISAIFYSLVQ

Sequences:

>Translated_430_residues
MDSVINKTENASAQVKVKSSWSKSDTLWVLGLYGTAVGAGTLFLPINAAQGGLIPLIIMALLALPMTFFAHRGLTRFVLS
GSNPEAGITEVVEEHFGVGMGKVITLLYFFAIYPILLVYSVALTNTVESFMQHQLNIAPPNRATLALILIIGLIAVVRLG
EQLIIKAMSVLVFPFVAVLLLLSVYLIPYWNTSIFNNVMPADGGISTILMALWLILPVMVFSFNHSPVISSFAVDRRKAH
GENADKQCSRILAFSHILMVVTVMFFVFSCVFSLSPANLAEAKAQNVSILTYLANHFDTPIIAYVAPIVAIIAITKSFFG
HYIGASEGFNGLIIKAARGKGKEVNLVTLNRVTAGFMLLTTWAVATINPNILGMIESLGGPIIALLLFIMPMYAIMKVPA
MKQYSGAISNVFVVIIGLVSISAIFYSLVQ
>Mature_430_residues
MDSVINKTENASAQVKVKSSWSKSDTLWVLGLYGTAVGAGTLFLPINAAQGGLIPLIIMALLALPMTFFAHRGLTRFVLS
GSNPEAGITEVVEEHFGVGMGKVITLLYFFAIYPILLVYSVALTNTVESFMQHQLNIAPPNRATLALILIIGLIAVVRLG
EQLIIKAMSVLVFPFVAVLLLLSVYLIPYWNTSIFNNVMPADGGISTILMALWLILPVMVFSFNHSPVISSFAVDRRKAH
GENADKQCSRILAFSHILMVVTVMFFVFSCVFSLSPANLAEAKAQNVSILTYLANHFDTPIIAYVAPIVAIIAITKSFFG
HYIGASEGFNGLIIKAARGKGKEVNLVTLNRVTAGFMLLTTWAVATINPNILGMIESLGGPIIALLLFIMPMYAIMKVPA
MKQYSGAISNVFVVIIGLVSISAIFYSLVQ

Specific function: Involved in the import of serine into the cell. May be required for phage C1 adsorption by interacting with DrcB. May also be involved in ampicillin sensitivity [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789160, Length=419, Percent_Identity=69.6897374701671, Blast_Score=593, Evalue=1e-171,
Organism=Escherichia coli, GI1789504, Length=435, Percent_Identity=49.8850574712644, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1789211, Length=411, Percent_Identity=36.9829683698297, Blast_Score=282, Evalue=4e-77,
Organism=Escherichia coli, GI145693183, Length=416, Percent_Identity=25, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789961, Length=404, Percent_Identity=25, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004694
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 46523; Mature: 46523

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSVINKTENASAQVKVKSSWSKSDTLWVLGLYGTAVGAGTLFLPINAAQGGLIPLIIMA
CCCHHCCCCCCCEEEEEECCCCCCCCEEEEEEHHHHHCCCEEEEEECCCCCCHHHHHHHH
LLALPMTFFAHRGLTRFVLSGSNPEAGITEVVEEHFGVGMGKVITLLYFFAIYPILLVYS
HHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VALTNTVESFMQHQLNIAPPNRATLALILIIGLIAVVRLGEQLIIKAMSVLVFPFVAVLL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSVYLIPYWNTSIFNNVMPADGGISTILMALWLILPVMVFSFNHSPVISSFAVDRRKAH
HHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
GENADKQCSRILAFSHILMVVTVMFFVFSCVFSLSPANLAEAKAQNVSILTYLANHFDTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHCCCH
IIAYVAPIVAIIAITKSFFGHYIGASEGFNGLIIKAARGKGKEVNLVTLNRVTAGFMLLT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEEEHHHHHHHHHHH
TWAVATINPNILGMIESLGGPIIALLLFIMPMYAIMKVPAMKQYSGAISNVFVVIIGLVS
HHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ISAIFYSLVQ
HHHHHHHHHC
>Mature Secondary Structure
MDSVINKTENASAQVKVKSSWSKSDTLWVLGLYGTAVGAGTLFLPINAAQGGLIPLIIMA
CCCHHCCCCCCCEEEEEECCCCCCCCEEEEEEHHHHHCCCEEEEEECCCCCCHHHHHHHH
LLALPMTFFAHRGLTRFVLSGSNPEAGITEVVEEHFGVGMGKVITLLYFFAIYPILLVYS
HHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VALTNTVESFMQHQLNIAPPNRATLALILIIGLIAVVRLGEQLIIKAMSVLVFPFVAVLL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSVYLIPYWNTSIFNNVMPADGGISTILMALWLILPVMVFSFNHSPVISSFAVDRRKAH
HHHHHHHCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
GENADKQCSRILAFSHILMVVTVMFFVFSCVFSLSPANLAEAKAQNVSILTYLANHFDTP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHCCCH
IIAYVAPIVAIIAITKSFFGHYIGASEGFNGLIIKAARGKGKEVNLVTLNRVTAGFMLLT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCEEEEEEEHHHHHHHHHHH
TWAVATINPNILGMIESLGGPIIALLLFIMPMYAIMKVPAMKQYSGAISNVFVVIIGLVS
HHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ISAIFYSLVQ
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]