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The map label for this gene is msbB [H]

Identifier: 167623745

GI number: 167623745

Start: 2171709

End: 2172647

Strand: Direct

Name: msbB [H]

Synonym: Shal_1815

Alternate gene names: 167623745

Gene position: 2171709-2172647 (Clockwise)

Preceding gene: 167623744

Following gene: 167623755

Centisome position: 41.55

GC content: 43.98

Gene sequence:

>939_bases
TTGTCTAGAAAGCCGAAATATTTTGACCGACGTTTTAGCTTTAGCCTGTTACACCCAAGATATTGGCTAACCTGGATCGC
GATTTTAGTGTTGCTAATATTTGGTCTTATGCCTGCTTGGCTTAGAGACCCTATTGCCCGCACACTTGCTATACTTGTGA
TGAAAATTGCTAAGAAGCCGATTAATGTTGCAAGGGCAAATTTAACCACCTGCTTTCCTGAAAAGTCCCATGACGAGATT
GAAGCGTTAGTAAAAGATAACGTTGAAAACTTTGTGATGATTTTATTGGCTCAATCTGAGCTACTTGCTAAATCTCGCGC
GAATATGAGACGTCGTGTACAGCTGCATGGATTTGAGCATGTAGAAAAGGCACGTGCTGCAGGTCAGCCAGTGATTTTTA
TCATGCCGCACGTGTGGGGAATTGAGTATGCTGGTCTTAGGCTTAATCTTGACCTGCCTATGGTATCGATGGCAAAAGCC
CATAAAAATGATCTGTTTAACTGGTTCAATAATCGCATGAGAAGCTCCCAAGGCGGAAACATCTACATGCGTGAAGCAGG
GATCAGAGCTTTGCTTTCGGAGTTAAAGCAAGGCAACAGCTTCTTTTATCTACCTGATGAAGATCTTGGTCGTGATAAGA
GTGTGTTTGCGCCGTTTCTGGGGACCACTAAGGCAACCTTGCCCGTTGTTGGCCGTTTAGCTCAGGCGGGTAACGCACAA
GTTATGCCGGTAAAGATTGGTTATGATCAAGTTAAGCGCCGTTTTGATCTAACGGTTATGCCTGCAATTGATCCAGAGAC
GATGCAAGGTAAAGAGAATGAAGCTATCGCCTTAAACAAGGCGGTTGAGCAGGTTATTCTAGCTTACCCGGAGCAGTATA
TGTGGTTCTTAAAAGTGCTTAAGACTCGTCCAGAAGGTGAGCCATCGATCTATAAATAA

Upstream 100 bases:

>100_bases
AAGAGGCTAACGCAAAGAAGTAATTGCTTTAGCATCATAATGAAGAGGCCACTCAATCGAGTGGCTTTTTCTGTTTCCAT
TTGCTGTAGAGGTTTTATTC

Downstream 100 bases:

>100_bases
CCTAGTGAGCGAAAATCTATCGCTCGCTAATGGATTTTTACTGAATAGATGTTGCTCCACAAAAAAGCCGCAATGGATAT
TGCGGCTTTTCTATGGCAAT

Product: lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSRKPKYFDRRFSFSLLHPRYWLTWIAILVLLIFGLMPAWLRDPIARTLAILVMKIAKKPINVARANLTTCFPEKSHDEI
EALVKDNVENFVMILLAQSELLAKSRANMRRRVQLHGFEHVEKARAAGQPVIFIMPHVWGIEYAGLRLNLDLPMVSMAKA
HKNDLFNWFNNRMRSSQGGNIYMREAGIRALLSELKQGNSFFYLPDEDLGRDKSVFAPFLGTTKATLPVVGRLAQAGNAQ
VMPVKIGYDQVKRRFDLTVMPAIDPETMQGKENEAIALNKAVEQVILAYPEQYMWFLKVLKTRPEGEPSIYK

Sequences:

>Translated_312_residues
MSRKPKYFDRRFSFSLLHPRYWLTWIAILVLLIFGLMPAWLRDPIARTLAILVMKIAKKPINVARANLTTCFPEKSHDEI
EALVKDNVENFVMILLAQSELLAKSRANMRRRVQLHGFEHVEKARAAGQPVIFIMPHVWGIEYAGLRLNLDLPMVSMAKA
HKNDLFNWFNNRMRSSQGGNIYMREAGIRALLSELKQGNSFFYLPDEDLGRDKSVFAPFLGTTKATLPVVGRLAQAGNAQ
VMPVKIGYDQVKRRFDLTVMPAIDPETMQGKENEAIALNKAVEQVILAYPEQYMWFLKVLKTRPEGEPSIYK
>Mature_311_residues
SRKPKYFDRRFSFSLLHPRYWLTWIAILVLLIFGLMPAWLRDPIARTLAILVMKIAKKPINVARANLTTCFPEKSHDEIE
ALVKDNVENFVMILLAQSELLAKSRANMRRRVQLHGFEHVEKARAAGQPVIFIMPHVWGIEYAGLRLNLDLPMVSMAKAH
KNDLFNWFNNRMRSSQGGNIYMREAGIRALLSELKQGNSFFYLPDEDLGRDKSVFAPFLGTTKATLPVVGRLAQAGNAQV
MPVKIGYDQVKRRFDLTVMPAIDPETMQGKENEAIALNKAVEQVILAYPEQYMWFLKVLKTRPEGEPSIYK

Specific function: Transfers myristate or laurate, activated on ACP, to (KDO)2-(lauroyl)-lipid IVA [H]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI1788161, Length=302, Percent_Identity=34.1059602649007, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI87082094, Length=310, Percent_Identity=30.9677419354839, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787292, Length=304, Percent_Identity=28.9473684210526, Blast_Score=144, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011921 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 35734; Mature: 35602

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKPKYFDRRFSFSLLHPRYWLTWIAILVLLIFGLMPAWLRDPIARTLAILVMKIAKKP
CCCCCCHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCC
INVARANLTTCFPEKSHDEIEALVKDNVENFVMILLAQSELLAKSRANMRRRVQLHGFEH
HHHHHCCHHEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VEKARAAGQPVIFIMPHVWGIEYAGLRLNLDLPMVSMAKAHKNDLFNWFNNRMRSSQGGN
HHHHHHCCCCEEEEECCCCCCEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
IYMREAGIRALLSELKQGNSFFYLPDEDLGRDKSVFAPFLGTTKATLPVVGRLAQAGNAQ
EEEEHHHHHHHHHHHHCCCCEEECCCHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCE
VMPVKIGYDQVKRRFDLTVMPAIDPETMQGKENEAIALNKAVEQVILAYPEQYMWFLKVL
EEEEECCHHHHHHHHCEEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
KTRPEGEPSIYK
HCCCCCCCCCCC
>Mature Secondary Structure 
SRKPKYFDRRFSFSLLHPRYWLTWIAILVLLIFGLMPAWLRDPIARTLAILVMKIAKKP
CCCCCHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCC
INVARANLTTCFPEKSHDEIEALVKDNVENFVMILLAQSELLAKSRANMRRRVQLHGFEH
HHHHHCCHHEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VEKARAAGQPVIFIMPHVWGIEYAGLRLNLDLPMVSMAKAHKNDLFNWFNNRMRSSQGGN
HHHHHHCCCCEEEEECCCCCCEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
IYMREAGIRALLSELKQGNSFFYLPDEDLGRDKSVFAPFLGTTKATLPVVGRLAQAGNAQ
EEEEHHHHHHHHHHHHCCCCEEECCCHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCE
VMPVKIGYDQVKRRFDLTVMPAIDPETMQGKENEAIALNKAVEQVILAYPEQYMWFLKVL
EEEEECCHHHHHHHHCEEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
KTRPEGEPSIYK
HCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]