Click here to switch to the map view.

The map label for this gene is fabD [H]

Identifier: 167623706

GI number: 167623706

Start: 2127670

End: 2128596

Strand: Direct

Name: fabD [H]

Synonym: Shal_1776

Alternate gene names: 167623706

Gene position: 2127670-2128596 (Clockwise)

Preceding gene: 167623705

Following gene: 167623707

Centisome position: 40.71

GC content: 45.42

Gene sequence:

>927_bases
ATGGAAAATACTGCTTTTGTATTCCCTGGACAAGGTTCTCAAGCATTGGGTATGTTAGCTGAGCTAGCACAAAACAATGC
TATCATTACAGAAACCTTTGCCCAAGCAAGCAGCACGCTTGGATATGATTTATGGGAGCTTGTACAACAAGGTCCTGTTG
AAACATTAAATGAAACGGATAAAACTCAGCCTGCTTTATTAGCGGCGAGTGTGGCTGTTTATCGTGCTTACTTAGCATCT
GGCAAGGCTATGCCTTCAGTGATGGCAGGCCATAGTTTAGGCGAGTACTCCGCACTCGTATGTGCTGGAGTGATTGATTT
TGAAGCGGCAATTAAATTAGTTGAGCTTCGTGGTCAGCTAATGCAGCAAGCGGTACCTGCGGGTACTGGTGCCATGTTTG
CGATTATTGGCTTAGATAACGACGCCATTGCTAAAGCATGTGAAGAGGCATCTGAAGGCGATGTGGTGAGCCCTGTTAAC
TATAACAGTCCAGGCCAAGTGGTTATCGCAGGTGAAAAAGCGGCTGTTGAGCGCGCTGCTGCACTGTGCAAAGCCAATGG
CGCAAAGATGGCCGTTGCATTGCCAGTAAGTGTGCCATCTCACTGCCAGTTAATGAAGCCTGCTGCCGATAAACTCGCAG
TTGCACTAGAATCAATTGAGTTCAGCGAACCTTCAGTAAAAGTGATTAATAATGTTGATGTTGCGAGTCCAACTTCAGCG
GCAGAAATTAAAGATGCATTAGTTCGTCAACTCTACTGTCCTGTGCGTTGGTCAGAAACTGTTGAGCTAATGGCTTCTGA
AGGTGTGACTAATTTGTTTGAAATGGGACCTGGTAAAGTATTAACAGGCCTGACAAAACGTATTAATCGCTCGCTTTCAG
CACAAGCTGTAAACGATGTAGCATCATTAACGGCGTTGACCGAATAA

Upstream 100 bases:

>100_bases
TAGTTCGTTTTTAATCGTCTTAGATAAAGTCATAGATATAGTCTTTGATAAAGTCTTATTGATAACAGTCAAAAGATGTT
GATTTAAAAGGGTGAAAAAT

Downstream 100 bases:

>100_bases
GGAAATCTGATGAGTATAAGTTTTGACCTGACTGGTAAAGTTGCTTTAGTTACTGGCGCTAGTCGTGGAATTGGGCGTGC
GGTCGCAGAAACTCTCGTTT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MENTAFVFPGQGSQALGMLAELAQNNAIITETFAQASSTLGYDLWELVQQGPVETLNETDKTQPALLAASVAVYRAYLAS
GKAMPSVMAGHSLGEYSALVCAGVIDFEAAIKLVELRGQLMQQAVPAGTGAMFAIIGLDNDAIAKACEEASEGDVVSPVN
YNSPGQVVIAGEKAAVERAAALCKANGAKMAVALPVSVPSHCQLMKPAADKLAVALESIEFSEPSVKVINNVDVASPTSA
AEIKDALVRQLYCPVRWSETVELMASEGVTNLFEMGPGKVLTGLTKRINRSLSAQAVNDVASLTALTE

Sequences:

>Translated_308_residues
MENTAFVFPGQGSQALGMLAELAQNNAIITETFAQASSTLGYDLWELVQQGPVETLNETDKTQPALLAASVAVYRAYLAS
GKAMPSVMAGHSLGEYSALVCAGVIDFEAAIKLVELRGQLMQQAVPAGTGAMFAIIGLDNDAIAKACEEASEGDVVSPVN
YNSPGQVVIAGEKAAVERAAALCKANGAKMAVALPVSVPSHCQLMKPAADKLAVALESIEFSEPSVKVINNVDVASPTSA
AEIKDALVRQLYCPVRWSETVELMASEGVTNLFEMGPGKVLTGLTKRINRSLSAQAVNDVASLTALTE
>Mature_308_residues
MENTAFVFPGQGSQALGMLAELAQNNAIITETFAQASSTLGYDLWELVQQGPVETLNETDKTQPALLAASVAVYRAYLAS
GKAMPSVMAGHSLGEYSALVCAGVIDFEAAIKLVELRGQLMQQAVPAGTGAMFAIIGLDNDAIAKACEEASEGDVVSPVN
YNSPGQVVIAGEKAAVERAAALCKANGAKMAVALPVSVPSHCQLMKPAADKLAVALESIEFSEPSVKVINNVDVASPTSA
AEIKDALVRQLYCPVRWSETVELMASEGVTNLFEMGPGKVLTGLTKRINRSLSAQAVNDVASLTALTE

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=308, Percent_Identity=34.7402597402597, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI27477045, Length=110, Percent_Identity=43.6363636363636, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=66.5584415584416, Blast_Score=398, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=28.7162162162162, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=291, Percent_Identity=29.2096219931272, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24665753, Length=315, Percent_Identity=32.0634920634921, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32116; Mature: 32116

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTAFVFPGQGSQALGMLAELAQNNAIITETFAQASSTLGYDLWELVQQGPVETLNETD
CCCCEEEECCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCHHHHHHHHCCCCHHHCCCC
KTQPALLAASVAVYRAYLASGKAMPSVMAGHSLGEYSALVCAGVIDFEAAIKLVELRGQL
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMFAIIGLDNDAIAKACEEASEGDVVSPVNYNSPGQVVIAGEKAAVERAA
HHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEECCCCCCCCCCEEEECCHHHHHHHH
ALCKANGAKMAVALPVSVPSHCQLMKPAADKLAVALESIEFSEPSVKVINNVDVASPTSA
HHHHCCCCEEEEEEECCCCCHHHHHCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHH
AEIKDALVRQLYCPVRWSETVELMASEGVTNLFEMGPGKVLTGLTKRINRSLSAQAVNDV
HHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLTALTE
HHHHHCCC
>Mature Secondary Structure
MENTAFVFPGQGSQALGMLAELAQNNAIITETFAQASSTLGYDLWELVQQGPVETLNETD
CCCCEEEECCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHCCHHHHHHHHCCCCHHHCCCC
KTQPALLAASVAVYRAYLASGKAMPSVMAGHSLGEYSALVCAGVIDFEAAIKLVELRGQL
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMFAIIGLDNDAIAKACEEASEGDVVSPVNYNSPGQVVIAGEKAAVERAA
HHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCEECCCCCCCCCCEEEECCHHHHHHHH
ALCKANGAKMAVALPVSVPSHCQLMKPAADKLAVALESIEFSEPSVKVINNVDVASPTSA
HHHHCCCCEEEEEEECCCCCHHHHHCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHH
AEIKDALVRQLYCPVRWSETVELMASEGVTNLFEMGPGKVLTGLTKRINRSLSAQAVNDV
HHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLTALTE
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]