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The map label for this gene is ligA [H]

Identifier: 167623672

GI number: 167623672

Start: 2087765

End: 2088652

Strand: Direct

Name: ligA [H]

Synonym: Shal_1741

Alternate gene names: 167623672

Gene position: 2087765-2088652 (Clockwise)

Preceding gene: 167623668

Following gene: 167623674

Centisome position: 39.94

GC content: 44.71

Gene sequence:

>888_bases
ATGGCCATGTTCACGATACGACTCCCTTCTTTAATCGCTAGCCTAATAGTGGCTTGTCTCTTTATTACAAACTATTCCTT
TGCGACATCCGCTGAAATCCCGCCAAACAATACTGATAAACCGTCAATCCAGTTAGCCTCTACAACCACGCAGCCAATGG
TCAATATCTCGGGCTACTTGGTCAGTGAAAAGCTAGACGGTGTGAGGGGATATTGGGATGGAAAAGCAATGTACAGTCGC
TCAGGCAGGTTGATTAATCTGCCGGCTTGGTTTATTGAGGGCTTTCCTGAGTTTCCTTTAGACGGTGAGTTATGGATTGA
GCGGGGGACGTTTGAGCAAGTATCGGCAACCGTTAGAAAAACCAAGGCCTCTGACGCTGAATGGGCCAAAGTTCGTTTTT
GGGTCTTTGATCTTCCGGATGATCCCAATATATTTGAATTGCGATATTACAGAGCGACAAAAGTACTGCAAGGTGTCAGT
CCATTTTTAGCCGTTATTAGGCAATATACATTGAGCAGCAATCAAGCATTAGATAGCCAGTTACAAGGCATTATTGCTGA
CAACGGTGAAGGTTTGATGTTACACAAGAAAACCGCCTTGTATAAAGCTGGCCGCAGTAAAGACATCGTTAAGCTTAAAC
CGTTTTATGATGCCGAAGCGGTAGTGGTTGCGCATACTTCAGGTAAAGGAAAGTTTAGCGGTATGTTGGGGGCTTTGGTG
GTAAAAAATGAGCAGGGAAAAGTGTTTAACTTAGGTTCTGGTTTCACACAGGAACAAAGGCTGGACCCACCTAAGATAGG
TAGCCAAGTGACCTACAAATACTATGGGCTAACTCAAAAAGGTACGCCAAGGTTCGCGAGCTTTTTGCGGGTGAGGCAAT
CTCAATAA

Upstream 100 bases:

>100_bases
TTGTGCAGACGAATATGGCGTAGAGCAGGAAATAGGGCTAGGCTTACTTCGTGGTGCACAGGATGTGCAAACTAACGTTG
AAAAACAGCTGCAAGGAGCA

Downstream 100 bases:

>100_bases
CAGATAAGTGAGATAACAGATAAGTGAGATAATAGGGCTTGGCTAAAAAATGATGATTAAAGGGCTTAACGAAGCAAAGC
CAATGGCGAGTTACTATAAA

Product: DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MAMFTIRLPSLIASLIVACLFITNYSFATSAEIPPNNTDKPSIQLASTTTQPMVNISGYLVSEKLDGVRGYWDGKAMYSR
SGRLINLPAWFIEGFPEFPLDGELWIERGTFEQVSATVRKTKASDAEWAKVRFWVFDLPDDPNIFELRYYRATKVLQGVS
PFLAVIRQYTLSSNQALDSQLQGIIADNGEGLMLHKKTALYKAGRSKDIVKLKPFYDAEAVVVAHTSGKGKFSGMLGALV
VKNEQGKVFNLGSGFTQEQRLDPPKIGSQVTYKYYGLTQKGTPRFASFLRVRQSQ

Sequences:

>Translated_295_residues
MAMFTIRLPSLIASLIVACLFITNYSFATSAEIPPNNTDKPSIQLASTTTQPMVNISGYLVSEKLDGVRGYWDGKAMYSR
SGRLINLPAWFIEGFPEFPLDGELWIERGTFEQVSATVRKTKASDAEWAKVRFWVFDLPDDPNIFELRYYRATKVLQGVS
PFLAVIRQYTLSSNQALDSQLQGIIADNGEGLMLHKKTALYKAGRSKDIVKLKPFYDAEAVVVAHTSGKGKFSGMLGALV
VKNEQGKVFNLGSGFTQEQRLDPPKIGSQVTYKYYGLTQKGTPRFASFLRVRQSQ
>Mature_294_residues
AMFTIRLPSLIASLIVACLFITNYSFATSAEIPPNNTDKPSIQLASTTTQPMVNISGYLVSEKLDGVRGYWDGKAMYSRS
GRLINLPAWFIEGFPEFPLDGELWIERGTFEQVSATVRKTKASDAEWAKVRFWVFDLPDDPNIFELRYYRATKVLQGVSP
FLAVIRQYTLSSNQALDSQLQGIIADNGEGLMLHKKTALYKAGRSKDIVKLKPFYDAEAVVVAHTSGKGKFSGMLGALVV
KNEQGKVFNLGSGFTQEQRLDPPKIGSQVTYKYYGLTQKGTPRFASFLRVRQSQ

Specific function: Catalyzes efficient strand joining on a single nicked DNA [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 32906; Mature: 32775

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMFTIRLPSLIASLIVACLFITNYSFATSAEIPPNNTDKPSIQLASTTTQPMVNISGYL
CEEEEEEHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEECCCCCCEEEECEEE
VSEKLDGVRGYWDGKAMYSRSGRLINLPAWFIEGFPEFPLDGELWIERGTFEQVSATVRK
EECCCCCCCCEECCCHHCCCCCCEEECCHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHH
TKASDAEWAKVRFWVFDLPDDPNIFELRYYRATKVLQGVSPFLAVIRQYTLSSNQALDSQ
HCCCCCCEEEEEEEEEECCCCCCEEEEEEHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHH
LQGIIADNGEGLMLHKKTALYKAGRSKDIVKLKPFYDAEAVVVAHTSGKGKFSGMLGALV
HCEEEEECCCEEEEEEHHHHHHCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCEEEEEE
VKNEQGKVFNLGSGFTQEQRLDPPKIGSQVTYKYYGLTQKGTPRFASFLRVRQSQ
EECCCCCEEECCCCCCHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AMFTIRLPSLIASLIVACLFITNYSFATSAEIPPNNTDKPSIQLASTTTQPMVNISGYL
EEEEEEHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEECCCCCCEEEECEEE
VSEKLDGVRGYWDGKAMYSRSGRLINLPAWFIEGFPEFPLDGELWIERGTFEQVSATVRK
EECCCCCCCCEECCCHHCCCCCCEEECCHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHH
TKASDAEWAKVRFWVFDLPDDPNIFELRYYRATKVLQGVSPFLAVIRQYTLSSNQALDSQ
HCCCCCCEEEEEEEEEECCCCCCEEEEEEHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHH
LQGIIADNGEGLMLHKKTALYKAGRSKDIVKLKPFYDAEAVVVAHTSGKGKFSGMLGALV
HCEEEEECCCEEEEEEHHHHHHCCCCCCEEEECCCCCCCEEEEEEECCCCCCCCEEEEEE
VKNEQGKVFNLGSGFTQEQRLDPPKIGSQVTYKYYGLTQKGTPRFASFLRVRQSQ
EECCCCCEEECCCCCCHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550458; 7542800; 9060431 [H]