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The map label for this gene is cysQ [H]

Identifier: 167623454

GI number: 167623454

Start: 1839228

End: 1840013

Strand: Direct

Name: cysQ [H]

Synonym: Shal_1523

Alternate gene names: 167623454

Gene position: 1839228-1840013 (Clockwise)

Preceding gene: 167623453

Following gene: 167623455

Centisome position: 35.19

GC content: 48.22

Gene sequence:

>786_bases
TTGAGCCATATATTTAAACAGGAGTGGTTAGAGCCGCTGCTCGATATTGCGACTGAAGCGGGCGATGCCATTATGGCTAT
CTATGAGAAAGAAGATCTAGGACTGGAGGTTAAGGCCGATGACAGTCCCGTTACTGCCGCAGATCTTACCAGTCATAGAG
TGATTATTGAAAAGCTGGCACAATTGACCCCCAATATCCCTGTATTGTCAGAAGAATCGACAGATATCGATTGGCAGCAG
AGACGTCATTGGCAATCATATTGGTTGATTGACCCACTTGATGGCACCAAAGAGTTTATTAAGCGTAATGGCGAGTTTAC
CGTCAATATCGCCTTTATCCATCATAATAGAGCGGTCGCGGGGGTGGTTTACGCGCCAGTGCTCGATAAGTGTTTCTTTG
GTGTACACGACCTTGGAGCGTGGTTAATTCAGGGAGGCAATAAGAGAAAACTAACTAAAGCGCATAAGCCTAAGGCAATC
CCGAGGATTGTCGGTAGTCGCTCTCATGCAAGCCCGGGGTTAGAAGCGTATCTGCAAGAGATTGGCGAGCACGAGATGAA
AAGCGTTGGCAGTTCGCTAAAGTTTTGTTTGCTGGCAGAAGGAGAGGCAGATATTTACCCTCGCTTGGGCCTAACCAGTG
AGTGGGATACCGCCGCGGCGCAGGCGGTGTTAGAGAGTGCTGGCGGCCGCGTACTGCAATATGACACAAACCTTCCTCTG
AATTACAATCAAAAGAGTGACATTCTGAACCCCTATTTTATCGCTTACGCTCCCCATTGGGATTAG

Upstream 100 bases:

>100_bases
TCTGTTTTCGACATTAAATGATTATTTGGTTATTAATTTTTATCGTTAAATGCTGGCATAATGAATCTATAACCTTCGTA
AATTATAGAGATAACTTACA

Downstream 100 bases:

>100_bases
GCTAGGGGAGAGTGCTGCGAACATTCGCGGGCTTAAAAAAGTTGTGCTTTGGTCGGATCTAAATATTCAAAAAATTAATA
ATAACTTTGGAGGGCAAACA

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSHIFKQEWLEPLLDIATEAGDAIMAIYEKEDLGLEVKADDSPVTAADLTSHRVIIEKLAQLTPNIPVLSEESTDIDWQQ
RRHWQSYWLIDPLDGTKEFIKRNGEFTVNIAFIHHNRAVAGVVYAPVLDKCFFGVHDLGAWLIQGGNKRKLTKAHKPKAI
PRIVGSRSHASPGLEAYLQEIGEHEMKSVGSSLKFCLLAEGEADIYPRLGLTSEWDTAAAQAVLESAGGRVLQYDTNLPL
NYNQKSDILNPYFIAYAPHWD

Sequences:

>Translated_261_residues
MSHIFKQEWLEPLLDIATEAGDAIMAIYEKEDLGLEVKADDSPVTAADLTSHRVIIEKLAQLTPNIPVLSEESTDIDWQQ
RRHWQSYWLIDPLDGTKEFIKRNGEFTVNIAFIHHNRAVAGVVYAPVLDKCFFGVHDLGAWLIQGGNKRKLTKAHKPKAI
PRIVGSRSHASPGLEAYLQEIGEHEMKSVGSSLKFCLLAEGEADIYPRLGLTSEWDTAAAQAVLESAGGRVLQYDTNLPL
NYNQKSDILNPYFIAYAPHWD
>Mature_260_residues
SHIFKQEWLEPLLDIATEAGDAIMAIYEKEDLGLEVKADDSPVTAADLTSHRVIIEKLAQLTPNIPVLSEESTDIDWQQR
RHWQSYWLIDPLDGTKEFIKRNGEFTVNIAFIHHNRAVAGVVYAPVLDKCFFGVHDLGAWLIQGGNKRKLTKAHKPKAIP
RIVGSRSHASPGLEAYLQEIGEHEMKSVGSSLKFCLLAEGEADIYPRLGLTSEWDTAAAQAVLESAGGRVLQYDTNLPLN
YNQKSDILNPYFIAYAPHWD

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI221625487, Length=253, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI5031789, Length=253, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7657236, Length=237, Percent_Identity=28.2700421940928, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1790659, Length=246, Percent_Identity=50, Blast_Score=222, Evalue=2e-59,
Organism=Escherichia coli, GI1788882, Length=240, Percent_Identity=28.75, Blast_Score=81, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71995897, Length=268, Percent_Identity=26.1194029850746, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71995905, Length=268, Percent_Identity=26.1194029850746, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24651149, Length=242, Percent_Identity=27.6859504132231, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24664922, Length=260, Percent_Identity=24.6153846153846, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24664926, Length=242, Percent_Identity=25.2066115702479, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29233; Mature: 29102

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHIFKQEWLEPLLDIATEAGDAIMAIYEKEDLGLEVKADDSPVTAADLTSHRVIIEKLA
CCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
QLTPNIPVLSEESTDIDWQQRRHWQSYWLIDPLDGTKEFIKRNGEFTVNIAFIHHNRAVA
HHCCCCCEECCCCCCCCHHHHHHHHHEEEEECCCCHHHHHHCCCCEEEEEEEEECCCCCH
GVVYAPVLDKCFFGVHDLGAWLIQGGNKRKLTKAHKPKAIPRIVGSRSHASPGLEAYLQE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHH
IGEHEMKSVGSSLKFCLLAEGEADIYPRLGLTSEWDTAAAQAVLESAGGRVLQYDTNLPL
HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCC
NYNQKSDILNPYFIAYAPHWD
CCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
SHIFKQEWLEPLLDIATEAGDAIMAIYEKEDLGLEVKADDSPVTAADLTSHRVIIEKLA
CCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
QLTPNIPVLSEESTDIDWQQRRHWQSYWLIDPLDGTKEFIKRNGEFTVNIAFIHHNRAVA
HHCCCCCEECCCCCCCCHHHHHHHHHEEEEECCCCHHHHHHCCCCEEEEEEEEECCCCCH
GVVYAPVLDKCFFGVHDLGAWLIQGGNKRKLTKAHKPKAIPRIVGSRSHASPGLEAYLQE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHH
IGEHEMKSVGSSLKFCLLAEGEADIYPRLGLTSEWDTAAAQAVLESAGGRVLQYDTNLPL
HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCC
NYNQKSDILNPYFIAYAPHWD
CCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]